Clinical trials: Lenses
Cataract
Visual Outcome and Visual Quality After Bilateral Implantation of the AcrySof® IQ IOL Compared to MI60® and Tecnis® IOL
The objective of the study is to compare the visual outcomes of three aspheric monofocal intraocular lenses after cataract surgery - ACRYSOF® IQ, Tecnis® and Akreos® MI60.
- Trial name
- NCT00760058
- Testing
- AcrySof® IQ IOL, Tecnis® Aspheric intraocular lens, Akreos® MI60 intraocular lens
- Where
- United States
- Sponsor
- Alcon Research
Visual Acuity
The Effects of Contact Lenses With UV/HEV-Filter on Visual Function
This is a 2-phase, single-site, non-dispensing, randomized, controlled, double-masked, 2x2 crossover study to objectively measure potential benefits of a new UV/HEV filter using psychophysical testing techniques.
- Trial name
- NCT05601544
- Testing
- ACUVUE OASYS 1-Day, ACUVUE OASYS MAX 1-Day, ACUVUE OASYS Multifocal
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract
A Comparison of Visual Function After Bilateral Implantation of Presbyopia-Correcting Intraocular Lenses (IOLs)
The purpose of this study is to evaluate visual and refractive parameters in a series of subjects bilaterally implanted with presbyopia-correcting intraocular lenses (IOLs) during cataract surgery.
- Trial name
- NCT01257217
- Testing
- AcrySof® IQ ReSTOR® +3.0 D Multifocal IOL Model SN6AD1, AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric IOL Model SND1TT, Acri.LISA® 366D IOL
- Volunteers
- 31 people
- Sponsor
- Alcon Research
Cataract
Clinical Comparison of a Monofocal eDOF IOL With a Monofocal IOL
Post-market, prospective, randomized, single-masked, multi-center clinical study investigating the safety and effectiveness of the Monofocal Extended Depth of Focus Intraocular Lens (Mono-EDoF IOL) when compared to a Standard…
- Trial name
- MonoeDOF (NCT04631068)
- Testing
- Cataract surgery
- Where
- 3 sites in France, Portugal and 1 more
- Volunteers
- 65 people
- Sponsor
- Advanced Vision Science, Inc.
Visual Acuity
Clinical Evaluation of Senofilcon A Contact Lenses Using a Novel Manufacturing Technology
This study is a multi-site, randomized, double-masked, 2×2 crossover design, 1-week dispensing study. Subjects will wear bilaterally both Test and Control lenses in a random order for 1-week each as a daily disposable modality…
- Trial name
- NCT04531241
- Testing
- ACUVUE® OASYS 1-DAY
- Where
- 7 sites in United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Primary Open Angle Glaucoma
Safety & Effectiveness Study of the Hydrus Microstent for Lowering IOP in Glaucoma Patients Undergoing Cataract Surgery (HORIZON)
This clinical trial is a prospective, randomized, controlled, multicenter, study. After informed consent is obtained, patients will be evaluated for eligibility based on glaucoma severity, eye health, and visual acuity.
- Trial name
- NCT01539239
- Testing
- Hydrus Aqueous Implant, Cataract surgery
- Where
- 38 sites in United States, Canada and 7 more
- Volunteers
- 1,143 people
- Sponsor
- Ivantis, Inc.
Systemic Lupus Erythematosus
WEUKBRE5716: Steroid-related Damage in Systemic Lupus Erythematosus (Hopkins)
The study is designed to assess the association between steroid exposure and five potentially steroid-related adverse events within a cohort of individuals with systemic lupus erythematosus (SLE).
- Trial name
- NCT01616472
- Testing
- Cumulative corticosteroid exposure
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
Cataract
Prospective Clinical Trial of the LensAR Laser System
The LensAR Laser System is used to create an opening in the anterior capsule of the lens and fragments the cataractous lens. The study will evaluate clinical outcomes compared to the contra-lateral eye treated with conventional…
- Trial name
- NCT01014702
- Testing
- LensAR Laser System, Conventional phacoemulsification
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- LensAR Incorporated
Refractive Errors
Air Optix Plus HydraGlyde Multifocal Daily/Extended Wear Contact Lenses
The purpose of this Post-Market Clinical Follow-Up (PMCF) study is to assess long term performance and safety of Air Optix plus HydraGlyde Multifocal soft contact lenses in a real-world setting when worn as daily wear or extended…
- Trial name
- NCT05886894
- Testing
- Lotrafilcon B multifocal soft contact lenses, Comfilcon A multifocal soft contact lenses
- Where
- 8 sites in United States
- Volunteers
- 351 people
- Sponsor
- Alcon Research
Cataract in Child
FLACS in Pediatric Patients Using FEMTO LDV-Z8
This study is a single center prospective observational case series. The framework of this clinical investigation is post market clinical follow up of pediatric FLACS using the Femto LDV Z8.
- Trial name
- NCT05241756
- Testing
- FLACS using FEMTO LDV-Z8
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Ziemer Ophthalmic Systems AG
Myopia
Clinical Comparison of Silicone Hydrogel and HEMA-based Daily Disposable Contact Lenses
The purpose of this trial was to compare the performance of an investigational daily disposable contact lens to a commercially available daily disposable contact lens.
- Trial name
- NCT01362907
- Testing
- Delefilcon A contact lens, Etafilcon A contact lens
- Volunteers
- 40 people
- Sponsor
- CIBA VISION
Cataract
Post-Implant Performance of the EC-3 IOL
The purpose of this study is to obtain data on the performance of the EC-3 lens at an interval of two years (and beyond) from subjects who were implanted.
- Trial name
- NCT01333345
- Where
- 3 sites in United States, France
- Volunteers
- 100 people
- Sponsor
- Aaren Scientific Inc.
Cataract, Lens Opacities
Multicentric Clinical Study on Isatis TF Trifocal Intraocular Lens
The study will be a multicentric, prospective open-label ethics committee approved clinical study to investigate safety, visual outcomes, contrast sensitivity and rotational stability after bilateral implantation of Isatis TF IOL…
- Trial name
- NCT04465344
- Testing
- Implantation of trifocal IOL, Isatis TF (device under investigation), Implantation of monofocal IOL, Isatis (control device)
- Where
- 7 sites in Czechia, Spain
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Cutting Edge SAS
Primary Open Angle Glaucoma, Healthy Subjects
Efficacy of 24-hour Intraocular Pressure Fluctuation Recording With the SENSIMED Triggerfish Contact Lens Sensor
The objectives of this study are to assess the safety and effectiveness of the SENSIMED Triggerfish® (TF) device in continuous recording of relative fluctuation in intraocular pressure (IOP).
- Trial name
- NCT01390779
- Testing
- SENSIMED Triggerfish
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Sensimed AG
Cataract After
Patient Acceptability of Autonomous Telemedicine
Patients will have an automated call supervised by a human clinician to check how they are after uncomplicated cataract surgery as part of their standard of care.
- Trial name
- NCT04885868
- Testing
- This study assess acceptability of autonomous conversation as part of cataract surgery follow up.
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ufonia
Myopia
Controlling Myopia Progression With Soft Contact Lenses (Contact Lens Control)
This study is to investigate whether novel soft contact lens optical designs can slow myopia progression
- Trial name
- NCT01829191
- Testing
- Soft Contact Test Lens A, Soft Contact Test Lens C
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Contact Lens Dry Eye
A Four Week Study of Azithromycin Ophthalmic Solution, 1% Versus Rewetting Drops in Subjects With History and Current Complaint of Contact Lens-Related Dry Eye (CLDE)
The primary objective of this study is to compare the duration of subject reported comfortable contact lens daily wear time in subjects with a history and current complaint of CLDE during a 29-day treatment period of azithromycin…
- Trial name
- NCT01105624
- Testing
- azithromycin ophthalmic solution, 1%, Visine® for Contacts®
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Merck Sharp & Dohme LLC
Myopia, Hyperopia
One-month Clinical Evaluation of Oté Sensation Multi-Purpose Solution Care System
The purpose of this study is to evaluate the clinical performance of the contact lens care product Oté Sensation in a representative population of soft contact lens wearers.
- Trial name
- NCT03278223
- Testing
- Test solution, Control solution
- Where
- 11 sites in United States, United Kingdom
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- OTE North America
Myopia
Evaluation of the Performance of Different Daily Disposable Lens Designs in Habitual Soft Contact Lens Wearers
The main objective of the study is to refit existing soft lens wearers with two different daily disposable contact lens types, Lens A and Lens B, to determine their performance after one week of wear.
- Trial name
- NCT04668989
- Testing
- stenfilcon A - (Test lens), kalifilcon A - (Control Lens)
- Where
- 4 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
A Dispensing Clinical Trial of a Study Test Silicone Hydrogel Lens Against Control Lens Over 1 Week
This is a 1-week dispensing, double-masked, randomized, bilateral study comparing the test lens against the control lens.
- Trial name
- NCT02500368
- Testing
- silicone hydrogel lens (test), enfilcon A lens (control)
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- CooperVision, Inc.
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