Clinical trials: Lenses
Myopia
A Study to Evaluate the Performance of Two Designs of Soft Toric Lenses
The objective of the study is to evaluate the product performance of the Bausch + Lomb toric investigational contact lenses compared to the currently marketed PureVision toric contact lenses.
- Trial name
- NCT01309867
- Testing
- Investigational Toric Lens, PureVision Toric Lens
- Where
- United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Cataract
Influence of Clearing Open-capsule Device on Refractive Predictability in Cataract Patients
CleaRing is intended to reduce posterior capsular opacification in cataract patients. The device is intended to be implanted together with standard posterior chamber IOL during cataract surgery.
- Trial name
- NCT04838730
- Testing
- Surgical procedure
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hanita Lenses
Dry Eye
Study to Evaluate a Contact Lens Lubricating and Rewetting Drop
The objective of this study is to evaluate the product performance of investigational lubricating and rewetting drops.
- Trial name
- NCT01267656
- Testing
- Lubricating and Rewetting Drops, AMO Blink Contacts Lubricant Eye Drops
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Cataract, Presbyopia
Evaluation of Long-Term Clinical Acceptability and Satisfaction With the IC-8 Intraocular Lens
The purpose of this study is to evaluate the long-term clinical acceptability and overall satisfaction with the IC-8 IOL at least 12 months post-IOL implantation.
- Trial name
- NCT03314766
- Testing
- IC-8 IOL
- Where
- 7 sites in Germany, Italy and 2 more
- Volunteers
- 64 people
- Sponsor
- AcuFocus, Inc.
Purpura, Thrombocytopaenic, Idiopathic
LENS - Long-term Eltrombopag Observational Study
A long term observational ocular safety study in adults who have received study medication (either active drug or placebo) in a phase II or III clinical study evaluating eltrombopag.
- Trial name
- LENS (NCT00643929)
- Testing
- Eltrombopag
- Where
- 71 sites in United States, Australia and 19 more
- Volunteers
- 164 people
- Sponsor
- GlaxoSmithKline
Primary Open Angle Glaucoma
Safety & Effectiveness Study of the Hydrus Microstent for Lowering IOP in Glaucoma Patients Undergoing Cataract Surgery (HORIZON)
This clinical trial is a prospective, randomized, controlled, multicenter, study. After informed consent is obtained, patients will be evaluated for eligibility based on glaucoma severity, eye health, and visual acuity.
- Trial name
- NCT01539239
- Testing
- Hydrus Aqueous Implant, Cataract surgery
- Where
- 38 sites in United States, Canada and 7 more
- Volunteers
- 1,143 people
- Sponsor
- Ivantis, Inc.
Contact Lens Wear
A Study to Evaluate the Safety and Efficacy of Kalifilcon A Daily Disposable Contact Lens
This study is to evaluate the safety and efficacy of a new silicone hydrogel daily disposable contact lens, kalifilcon A compared to the Bausch + Lomb Biotrue ONE day® daily disposable contact lens when worn by current soft…
- Trial name
- NCT04158466
- Testing
- Kalifilcon A Daily Disposable Contact Lenses, Biotrue ONEday Daily Disposable Contact Lenses
- Where
- 16 sites in United States
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia
BIOCLEAN FIRST CARE EX in Combination With Biofinity Lens
To determine if patients are unreactive to the lens care solution / Biofinity combination.
- Trial name
- NCT02196766
- Testing
- Bioclean First Care EX / comfilcon A, Aosept Clearcare / comfilcon A
- Where
- 3 sites in Japan
- Volunteers
- 30 people
- Sponsor
- CooperVision, Inc.
Cataract
India PanOptix Post Marketing Study
The purpose of this Post Marketing Study is to study the safety and effectiveness of the ACRYSOF IQ PanOptix intraocular lens (IOL) in an Indian population.
- Trial name
- NCT03706066
- Testing
- Acrysof IQ PanOptix IOL, Cataract surgery
- Where
- 5 sites in India
- Volunteers
- 80 people
- Sponsor
- Alcon Research
Cataract, Lens Opacities
Clinical Study to Evaluate Clinical Outcomes of LuxSmart IOL as Compared With LuxGood IOL
This study is a multicentric, prospective, randomised, controlled, post-market clinical follow up (PMCF) study to investigate safety, visual outcomes and contrast sensitivity after bilateral implantation of either LuxSmart IOLs…
- Trial name
- NCT06105190
- Testing
- Implantation of premium monofocal IOL, LuxSmart (device under investigation), Implantation of monofocal IOL, LuxGood (control device)
- Where
- 8 sites in Austria, Czechia and 4 more
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Cutting Edge SAS
Myopia
Evaluation of Two Daily Disposable Contact Lenses.
The objective of this clinical study is to evaluate the product performance of SofLens daily disposable contact lenses packaged in the investigational Test solution versus SofLens daily disposable contact lenses packaged in…
- Trial name
- NCT01300065
- Testing
- Experimental- Soflens, Marketed - Soflens
- Where
- United States
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Cataract Senile
Evaluation of a Spherical Hydrophilic Acrylic Intraocular Lens
Evaluation of the clinical safety and effectiveness of hydrophilic acrylic intraocular lens
- Trial name
- NCT04998409
- Testing
- Monofocal lens
- Where
- Germany
- Volunteers
- 242 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract
Clinical Safety and Efficacy of CT ASPHINA 509 Lenses
Clinical safety and efficacy of CT ASPHINA 509 IOLs after implantation
- Trial name
- UVEA509 (NCT03145116)
- Testing
- CT ASPHINA 509
- Where
- Germany
- Volunteers
- 95 people
- Sponsor
- Carl Zeiss Meditec AG
Cosmetic Appearance
Cosmetic Contact Lenses Post-Market Clinical Follow-up Study
The purpose of this post-market study is to gather long term performance and safety data on FreshLook® One-day Colors cosmetic contact lenses and DAILIES FreshLook® ILLUMINATE cosmetic contact lenses in participants 12 years of…
- Trial name
- NCT06517316
- Testing
- Nelfilcon A plano cosmetic contact lenses
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Alcon Research
Cataract, Glaucoma
Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)
This trial is a randomized study to evaluate the Bimatoprost Implant System used in combination with the SpyGlass IOL to Timolol Ophthalmic Solution in participants with mild to moderate open-angle glaucoma or ocular hypertension…
- Conditions
- Cataract, Glaucoma, Ocular Hypertension
- Trial name
- NCT07218796
- Testing
- Bimatoprost Implant System, SpyGlass IOL, Timolol Maleate Ophthalmic Solution, 0.5%
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- SpyGlass Pharma, Inc.
Cataract
EDoF IOLs vs Monofocal IOL
prospective, comparative (3 arms), randomized, multicentric clinical trial
- Trial name
- NCT03172351
- Testing
- EDoF1, Monofocal, EDoF2
- Where
- Germany
- Volunteers
- 216 people
- Sponsor
- Carl Zeiss Meditec AG
Presbyopia, Refractive Error
Dispensing Study to Assess the Visual Performance of Optimised Prototype Contact Lenses
The aim of this study is to assess the visual performance of multiple optimised prototype soft contact lens designs compared to commercially available contact lenses.
- Trial name
- NCT02484586
- Testing
- Etafilcon A, Nelfilcon A, Nesofilcon A
- Where
- Australia
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Brien Holden Vision
Myopia
Lens Fitting Evaluation of CooperVision MyDay™ Compared With 1-DAY ACUVUE® TruEye® and DAILIES TOTAL1®
Lens Fitting Evaluation of CooperVision MyDay™ Compared with 1-DAY ACUVUE® TruEye® and DAILIES TOTAL1®
- Trial name
- NCT02341859
- Testing
- stenfilcon A, delefilcon A, narafilcon A
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- CooperVision, Inc.
Presbyopia
Multifocal Contact Lenses Fitting Methods Comparison
The purpose of this study was to compare the clinical performance of two fitting approaches for multifocal contact lenses.
- Trial name
- NCT05734846
- Testing
- Control Lenses (control fitting approach), Test Lenses (test fitting approach)
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- CooperVision, Inc.
Cataract
Safety and Effectiveness of a Multifocal Intraocular Lens (IOL)
To evaluate the safety and effectiveness of the ZM900 Tecnis Multifocal lens. Results from two studies (an original study with 125 multifocal and 123 monofocal subjects, protocol DIOL-101-TCNS, and an expansion study with 222…
- Trial name
- NCT00747565
- Testing
- Tecnis ZM900 Multifocal Intraocular Lens, CeeOn 911A monofocal IOL
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
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