Clinical trials: Lenses
Myopia
Dispensing Evaluation of Printed Etafilcon A With Polyvinylpyrrolidone (PVP)
The purpose of this study is to evaluate the lens fit (mechanical and cosmetic lens fit) of the printed etafilcon A with polyvinylpyrrolidone (PVP).
- Trial name
- NCT01180777
- Testing
- etafilcon A (A), etafilcon A (B), etafilcon A (C)
- Where
- 6 sites in United States
- Volunteers
- 95 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataracts, Meibomian Gland Dysfunction (MGD)
A Post-Market Evaluation of LipiFlow Treatment in Cataract Surgery Practice
This is a post-market, prospective, randomized, multi-center, bilateral, open-label, cross-over, comparative clinical study. Study group will undergo preoperative LipiFlow treatment and Control group will not receive preoperative…
- Trial name
- NCT03708367
- Testing
- LipiFlow Thermal Pulsation System
- Where
- 5 sites in United States
- Volunteers
- 117 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Refractive Errors
Clinical Evaluation of Two Monthly Contact Lenses
The purpose of this study is to explore overall vision with BIOFINITY® ENERGYS™ contact lenses as compared to BIOFINITY® contact lenses after one week of wear.
- Trial name
- NCT03459131
- Testing
- Comfilcon A with Digital Zone Optics™ contact lenses, Comfilcon A contact lenses
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Alcon Research
Cataract
Ocular Biodistribution Study for Topically Applied ESBA105
The purpose of this study is to determine whether ESBA105, a single-chain (scFv) antibody against TNF-alpha, efficiently penetrates into the anterior chamber and the vitreous body upon topical administration to the eye.
- Trial name
- NCT00820014
- Where
- 2 sites in Switzerland
- Volunteers
- 79 people
- Sponsor
- ESBATech AG
Aphakia, Corneal Astigmatism
Evaluation of the Safety and Performance of the HARMONI® Toric Lens
The purpose of this study was to evaluate the safety and effectiveness of the HARMONI® Modular Intraocular Lens System with a toric optic (HMTIOL) in subjects with pre-existing corneal astigmatism in need of cataract surgery.
- Conditions
- Aphakia, Corneal Astigmatism, Cataract
- Trial name
- NCT03050697
- Testing
- HARMONI® Modular Toric Intraocular Lens, Cataract extraction with intraocular lens (IOL) implantation
- Where
- New Zealand
- Volunteers
- 16 people
- Sponsor
- ClarVista Medical
Astigmatism, Myopia
Comparative Clinical Evaluation of Soft Toric Lens Designs
This study is evaluating the initial fit of toric contact lenses.
- Trial name
- NCT01552876
- Testing
- etafilcon A, nelfilcon A, Filcon II 3
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Clinical Evaluation of Daily Disposable Etafilcon A Cosmetic Contact Lenses (2022)
This is a multi-site, 4-visit, brand-masked, bilateral, 2x2 cross-over dispensing study to evaluate visual acuity.
- Trial name
- NCT05480514
- Testing
- TEST LENS, CONTROL LENS
- Where
- 2 sites in Hong Kong
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Astigmatism
A Clinical Comparison of Two Soft Toric Contact Lenses
The aim of this study is to compare the short-term clinical performance of two toric contact lenses.
- Trial name
- NCT06758089
- Testing
- Lens 1 (ocufilcon D), Lens 2 (somofilcon A)
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- CooperVision International Limited (CVIL)
Open-angle Glaucoma
Safety and Efficacy of the GTS400 Stent in Conjunction With Cataract
To evaluate the safety and efficacy of the Glaukos Trabecular Micro-Bypass Stent Model GTS400 in conjunction with cataract surgery, compared to cataract surgery only, in subjects with mild to moderate open angle glaucoma.
- Trial name
- NCT00721968
- Testing
- Glaucoma Stent Surgery (GTS400 Stent), cataract surgery alone
- Volunteers
- 62 people
- Sponsor
- Glaukos Corporation
Intraocular Lens Replacement, Intraoperative Floppy Iris Syndrome
Intraoperative Floppy Iris Syndrome Undergoing Intraocular Lens Replacement Surgery
The purpose of this study is to evaluate the effect of OMS302 on the signs of Intraoperative Floppy Iris Syndrome in patients at risk.
- Trial name
- NCT02093689
- Testing
- Part 1 OMS302, Part 2 OMS302
- Where
- 2 sites in Austria, Germany
- Volunteers
- 18 people
- Sponsor
- Omeros Corporation
Contact Lens Discomfort
Safety, Tolerability and Pharmacodynamics of AZR-MD-001 in Contact Lens Discomfort (CLD)
A two stage, multi-center, vehicle-controlled study to determine common symptoms in patients with Contact Lens Discomfort (CLD) in Stage 1 and to evaluate the safety, tolerability, and pharmacodynamics of AZR-MD-001 in Stage 2.
- Trial name
- NCT05548491
- Testing
- AZR-MD-001 ointment/semi-solid drug
- Where
- 2 sites in Australia
- Volunteers
- 67 people
- Sponsor
- Azura Ophthalmics
Glaucoma, Cataract
Observational Study to Evaluate Long Term Outcomes for Ocular Hypertension and Glaucoma Patients Treated With the SpyGlass Bimatoprost Implant System / IOL Combination
The goal of this clinical trial is to further observe and learn if the SpyGlass Pharma Bimatoprost Implant System / IOL Combination works to treat cataracts and either ocular hypertension or glaucoma.
- Conditions
- Glaucoma, Cataract, Ocular Hypertension
- Trial name
- NCT07154810
- Where
- Honduras
- Volunteers
- 23 people
- Sponsor
- SpyGlass Pharma, Inc.
Refractive Errors
Clinical Characterization of an Investigational Soft Silicone Hydrogel Contact Lens
The primary objective of this study is to evaluate the overall clinical performance of an investigational silicone hydrogel contact lens over 2 weeks of daily wear.
- Trial name
- NCT04631796
- Testing
- Lehfilcon A contact lenses, Multipurpose disinfection solution
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Alcon Research
Cataract, Astigmatism
Safety and Effectiveness of the Akreos Toric Intraocular Lens.
The purpose of this study is to evaluate the safety and effectiveness of the Akreos Toric IOL following cataract surgery.
- Trial name
- NCT00825513
- Testing
- Akreos Toric IOL, Akreos Advanced Optics Aspheric Intraocular Lens (Akreos AO)
- Where
- Sweden
- Volunteers
- 198 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Comparative Study of Two Marketed 1-day Soft Contact Lenses
This study is designed to evaluate ocufilcon D lens compared to ocufilcon B lens in a 1-week crossover, daily wear regimen.
- Trial name
- NCT01464255
- Testing
- ocufilcon D, ocufilcon B
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- CooperVision, Inc.
Myopia
Dispensing Evaluation of a Prototype Contact Lens and a Marketed Contact Lens
The purpose of this study is to compare visual acuity and redness of eyes between a prototype contact lens and an already marketed contact lens.
- Trial name
- NCT01094743
- Testing
- galyfilcon A prototype lens, lotrafilcon B lens
- Where
- 2 sites in United States
- Volunteers
- 52 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract
Acular LS vs. Nevanac in Post op Inflammation Following Cataract Surgery
The purpose of this study is to compare the clinical outcomes, safety and efficacy in patients randomized to receive either ketorolac or nepafanac following cataract surgery.
- Trial name
- NCT00348582
- Testing
- Ketorolac, Nepafenac
- Where
- United States
- Sponsor
- Innovative Medical
Cataract
A Study of Cataract Surgery With the Femtosecond Laser
The purpose of this study is to evaluate the feasibility of using the Femtosecond Laser System to perform surgical maneuvers during cataract extraction surgery.
- Trial name
- NCT00922571
- Testing
- FS Laser Surgery, FS Laser System
- Volunteers
- 100 people
- Sponsor
- Abbott Medical Optics
Cataract
Post-market Evaluation of Clinical Outcomes in China for the TECNIS Model ZMT
This is a prospective, multicenter, single-arm, open-label clinical study of the commercially available TECNIS Multifocal Toric 1-Piece IOL. The study will enroll up to 120 subjects from up to 8 sites in China.
- Trial name
- NCT04954898
- Testing
- Study Lens: TECNIS Multifocal Toric 1-piece lens, Model ZMT
- Where
- 7 sites in China
- Volunteers
- 102 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Refractive Ametropia
The Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses
The purpose of this study is to assess the clinical performance of two reusable silicone hydrogel contact lenses when worn on a daily wear basis.
- Trial name
- NCT05766787
- Testing
- Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
- Where
- 15 sites in United States
- Volunteers
- 190 people
- Sponsor
- Alcon Research
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