Clinical trials: Lenses
Cataract
Evaluation of Clinical Outcomes Following Implantation of a Sub-2mm Hydrophilic MICS Intraocular Lens
The objective of this study is to evaluate clinical outcomes following sub-2 mm micro-incision cataract surgery (MICS) and intraocular lens (IOL) implantation.
- Trial name
- NCT01615861
- Testing
- IOL implantation
- Where
- France
- Volunteers
- 103 people
- Sponsor
- Bausch & Lomb Incorporated
Keratitis; Infectious Disease (Manifestation)
Pseudomonal Type Three Secretion System and Contact Lens Associated Microbial Keratitis
Microbial infection of the cornea, also known as microbial keratitis, causes severe corneal inflammation that could result in permanent visual loss.
- Trial name
- NCT01925846
- Where
- Taiwan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Colonic Polyp
Extra Wide Field of View Lens Study
The goal of this observation study is to learn about the feasibility of a new colonoscope which provides the physician an extra-wide field of view during a screening colonoscopy.
- Trial name
- EFOV (NCT06483503)
- Testing
- EFOV Colonoscope
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pentax Medical
Cataract, Presbyopia
Retrospective Clinical Investigation of the Safety and Performance of 640PM Trifocal IOL Implantation in Patients With Cataract and/or Ametropia (Hyperopia, Myopia) and/or Presbyopia
The clinical investigation objective is to evaluate safety and performance outcomes of trifocal IOL implantation to improve vision in patients with cataract and/or ametropia (hyperopia, myopia) and/or presbyopia.
- Conditions
- Cataract, Presbyopia, Hyperopia, Myopia
- Trial name
- NCT05735990
- Testing
- Intraocular lens
- Where
- Spain
- Volunteers
- 21 people
- Sponsor
- Medicontur Medical Engineering Ltd
Accomodation
Effect of Biofeedback Training on Accommodation During Multifocal Lens Wear in Young Adults
This study will examine the accommodative behavior in young adults wearing multifocal soft contact lenses. undergoing myopia control treatments.
- Trial name
- NCT05684250
- Testing
- Auditory biofeedback training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Hyperopia
Pilot Dispensing Evaluation of a Plus Power Lens
The purpose of this study is to compare the performance of the ACUVUE® ADVANCE® Plus lenses against ACUVUE® ADVANCE® lenses in the plus power parameters.
- Trial name
- NCT01228591
- Testing
- Acuvue Advance Plus, Acuvue Advance
- Where
- 3 sites in United States
- Volunteers
- 38 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Wrinkles
Evaluation of the Safety and Efficacy of the Pico Laser With a Specialized Lens Array for the Treatment of Wrinkles
The purpose of this study is to evaluate the efficacy and safety of the treatment of wrinkles using the picosecond 755nm Alexandrite laser.
- Trial name
- NCT02091089
- Testing
- 755nm Alexandrite laser
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cynosure, Inc.
Contact Lens Discomfort
Neurolens and Contact Lens Discomfort
The objective of this study is to determine how neurolens® influences contact lens discomfort in uncomfortable myopic soft contact lenses wearers.
- Trial name
- NCT05801991
- Testing
- Neurolens
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Cataracts
Clinical Investigation of AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric Intraocular Lens (IOL)
The purpose of this study is to evaluate the safety and effectiveness of an investigational multifocal toric intraocular lens (IOL) compared to an FDA-approved multifocal IOL.
- Trial name
- NCT01424189
- Testing
- AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric IOL, AcrySof® ReSTOR® Multifocal IOL Model SA60D3
- Volunteers
- 677 people
- Sponsor
- Alcon Research
Cataract
Clinical Outcomes of Patients Bilaterally Implanted With the TECNIS® Symfony or TECNIS® Symfony Toric Extended Range of Vision IOL
In With increased patients' demand for a spectacle-free lifestyle and technological advancements, cataract surgery with multifocal intraocular lens (IOL) implantation has become an effective solution for correcting presbyopia in…
- Trial name
- NCT03997890
- Testing
- Cataract surgery with binocular implantation of either Symfony (ZXR00) or Symfony toric (ZXT) IOLs
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Yonsei University
Cataract, Retinitis Pigmentosa (RP)
Impact of Capsular Tension Ring on Intraocular Lens Position in Retinitis Pigmentosa Cataract Patients
This is a self-controlled randomized clinical trial to investigate the effect of capsular tension ring (CTR) implantation on intraocular lens (IOL) position in cataract patients with retinitis pigmentosa(RP).
- Trial name
- NCT07126470
- Testing
- CTR implantation
- Where
- 3 sites in China
- Volunteers
- 88 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Healthy
Clinical Performance of All-in-One Light Multi-purpose for Silicone Hydrogel Contact Lenses
A clinical trial was conducted to assess the safety and acceptability of the Sauflon Multipurpose Solution when used with four different silicone hydrogel contact lens brands and one conventional hydrogel control lens was…
- Trial name
- NCT01392937
- Testing
- All-in-One Light multipurpose, Aquify care
- Where
- United Kingdom
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Sauflon Pharmaceuticals Ltd
Pseudoaphakia
Characterization and Causative Factors of Negative Dysphotopsia
The present study is designed as an exploratory study, seeking to investigate the correlation of patient complaints to subjective or objective measurement methods.
- Trial name
- NDys (NCT04224129)
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Cataract, Refractive Error
A Comparative Study of TECNIS Symfony Plus IOL and a Trifocal IOL
This is a multicenter, prospective, randomized, subject- and evaluator-masked, bilateral-implant study conducted at up to 15 sites worldwide.
- Trial name
- NCT04156737
- Testing
- TECNIS Symfony plus IOL Model ZHR00V, Trifocal Intraocular lens
- Where
- 5 sites in New Zealand, Philippines and 1 more
- Volunteers
- 205 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Atrial Fibrillation
Clinical Characteristics and Prognostic Factors of Atrial Fibrillation at a Tertiary Center of Pakistan - From a South-Asian Lens - a Retrospective Study.
To evaluate the clinical characteristics and management purseued for atrial fibrillation in a tertiary care center of Pakistan. We aimed at looking baseline characteristics and associated co-morbid conditions and primary…
- Trial name
- NCT05082558
- Testing
- No intervention, as this was retrospective study.
- Where
- Pakistan
- Volunteers
- 651 people
- Sponsor
- Aga Khan University Hospital, Pakistan
Cataract
A Comparison of Aspheric Toric Intraocular Lens (IOL) Implantation Versus Aspheric Non-Toric Lens Implantation
The purpose of this study was to evaluate and compare uncorrected distance visual acuity measurement in pseudophakic subjects with bilateral implantation of an AcrySof IQ Toric Intraocular Lens (IOL) versus bilateral implantation…
- Trial name
- NCT01225926
- Testing
- Toric T3 - T9, IQ SN60WF
- Volunteers
- 24 people
- Sponsor
- Alcon Research
Cataracts
A Comparative Pilot Study Of High-Order Aberrations With Aspheric IOL Models SN60WF and ZCB00
The purpose of this study was to prospectively compare high-order aberrations between eyes implanted with the AcrySof® Natural IQ (SN60WF) intraocular lens (IOL) versus those implanted with the Tecnis ZCB00 IOL.
- Trial name
- NCT01105585
- Testing
- Tecnis 1-piece Aspheric Acrylic (ZCB00) IOL, AcrySof Natural IQ (SN60WF) IOL
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Alcon Research
Refractive Errors, Myopia
Clinical Performance Assessment of Two Silicone Hydrogel Daily Disposable Contact Lenses
The purpose of this study is to assess the overall clinical performance of a contact lens made with a modified manufacturing process.
- Trial name
- NCT05725317
- Testing
- LID220365 contact lens, LID006961 contact lens
- Where
- 7 sites in United States
- Volunteers
- 114 people
- Sponsor
- Alcon Research
Dry Eye
Investigating iLux Efficacy in Contact Lens Wearers With Evaporative Dry Eye Disease
The purpose of this clinical trial is to investigate the efficacy of a single iLux® treatment in symptomatic CL wearers who have DED (according to the TFOS DEWS II diagnostic criteria), of the evaporative dry eye disease subtype…
- Trial name
- SHEEPDOG (NCT04159935)
- Testing
- iLux® system
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Cataract, Corneal Astigmatism
Evaluation of the Rotational Stability of the Tecnis Toric II IOL
This is a prospective, multicenter, single-arm, open-label clinical study of the commercially available TECNIS Toric II IOL. The study will be conducted in up to 192 subjects needing unilateral or bilateral cataract surgery in up…
- Trial name
- STEELE (NCT04327518)
- Testing
- TECNIS® Toric II
- Where
- 7 sites in United States
- Volunteers
- 125 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
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