Clinical trials: Lenses
Cataracts Infantile, Subluxation of Lens
Anterior Versus Posterior Artisan Intraocular Lens Fixation in Aphakic Children With Insufficient Capsular Support.
The Artisan lens (Artisan Aphakic, Ophtec BV) is an iris- claw lens designed for implantation in children with insufficient capsular support.
- Conditions
- Cataracts Infantile, Subluxation of Lens, Intraocular Lens Complication, Corneal Endothelial Cell Loss
- Trial name
- NCT06396156
- Testing
- Anterior enclavation, Posterior enclavation
- Where
- 2 sites in Egypt
- Volunteers
- 32 people
- Sponsor
- Cairo University
Myopia
A Comparison of Silicone Hydrogel Contact Lenses: AIR OPTIX® COLORS Versus AIR OPTIX® AQUA
The purpose of this study was to compare the overall fit of AIR OPTIX® COLORS to AIR OPTIX® AQUA contact lenses.
- Trial name
- NCT01635920
- Testing
- Lotrafilcon B contact lens with color, Lotrafilcon B contact lens
- Volunteers
- 258 people
- Sponsor
- Alcon Research
Cataract, Intraocular Lenses
The Effect of Eye Exercises on Visual Function and Quality of Life After Multifocal Intraocular Lens Implantation
The goal of this clinical trial is to examine the effects of eye exercises on visual function and quality of life in cataract patients undergoing multifocal intraocular lens implantation.
- Trial name
- NCT05958459
- Testing
- Eye Exercise, no intervention
- Volunteers
- 60 people
- Sponsor
- Idrıs Dogan
Marfan Syndrome, Lens Subluxation or Dislocation
Surgical Treatment of Marfan Syndrome With Subluxation Lens
To analyze the postoperative visual effects, and to compare the safety and efficacy of different surgical treatment with of Marfan Syndrome with subluxation lens.
- Trial name
- NCT05578469
- Testing
- surgical treatment of Marfan Syndrome with subluxation lens
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cataract
A Clinical Study of the ACRYSOF® IQ EDF Intraocular Lens (IOL)
The purpose of the study is to demonstrate the safety and performance of the ACRYSOF® IQ EDF IOL.
- Trial name
- NCT03010254
- Testing
- ACRYSOF® IQ Extended Depth of Focus IOL, ACRYSOF® IQ Monofocal IOL, Cataract surgery
- Where
- 21 sites in Australia, Canada and 2 more
- Volunteers
- 322 people
- Sponsor
- Alcon Research
Contact Lens Wear
A Safety and Effectiveness Study of a New Preservative Free Rewetting Drop
The objective of this study is to evaluate the safety and effectiveness of lubricating and rewetting drop (Test) compared to OPTI-FREE® Replenish® Rewetting Drops (Control) when used by habitual contact lens wearers to…
- Trial name
- NCT04175340
- Testing
- BL-300-PFM04, OPTI-FREE
- Where
- 15 sites in United States
- Volunteers
- 369 people
- Sponsor
- Bausch & Lomb Incorporated
Presbyopia, Near Vision
The Impact of Light Conditions on the Efficacy of Multifocal Intraocular Lens Implantation in Activities of Daily Living
Primary objective of this study is to identify the optimal task lighting conditions (in terms of light intensity and light temperature) for 10 activities of daily living (ADLs) that require near or intermediate vision acuity in a…
- Conditions
- Presbyopia, Near Vision, Reading, Daily Activities
- Trial name
- NCT05359380
- Testing
- ADL performance
- Where
- Greece
- Volunteers
- 75 people
- Sponsor
- Democritus University of Thrace
Cataract
Multi-formula Optimization of Second Eye Refinement According to Direction of the Prediction Error of the First Eye
Prediction errors for the first (PE1) and second eyes (PE2) were obtained in the intra-ocular lens power calculation for 4 formulae (HofferQ, SRK II, SRK/T and Holladay 1).
- Trial name
- NCT02270879
- Testing
- Phacoemulsification cataract surgery
- Volunteers
- 156 people
- Sponsor
- Centro Hospitalar do Baixo Vouga
Myopia, Myopia Progression
Myopia Control Spectacle Lens Cessation Study
To quantify myopic progression (cycloplegic spherical equivalent refraction - cSER) following the cessation of use of specific spectacle lenses.
- Conditions
- Myopia, Myopia Progression, Juvenile Myopia
- Trial name
- BIRCH (NCT05893979)
- Testing
- Spectacle Lenses
- Where
- 8 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Cataract, Inflammation
Mapracorat Ophthalmic Suspension, 3% for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery
The objective of this clinical study is to compare the safety and efficacy of mapracorat ophthalmic suspension, 3% with its vehicle for the treatment of postoperative inflammation and pain following cataract surgery.
- Conditions
- Cataract, Inflammation, Surgery
- Trial name
- NCT01591161
- Testing
- Mapracorat
- Where
- United States
- Volunteers
- 369 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract
A Safety and Efficacy Study of a Dexamethasone Drug Delivery System for Postoperative Inflammation and Pain After Cataract Surgery
This is a safety and efficacy study of a Dexamethasone Drug Delivery System for anterior segment inflammation and pain following cataract extraction with lens implantation.
- Trial name
- NCT01605942
- Testing
- Dexamethasone Drug Delivery System
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Allergan
Visual Acuity
Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Hyperopic Population
This is a 6-visit, subject-masked, multi-site, 2×3 crossover dispensing trial that will last approximately 2 - 4 months.
- Trial name
- NCT04567186
- Testing
- Investigational senofilcon A C3 Multifocal Lens, delefilcon A Multifocal Lens
- Where
- 7 sites in United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Evaluation of Approved Contact Lenses
This is a prospective, randomized, controlled, subject-masked, bilateral, dispensing, multi-site, 2 lenses × 3 wearing periods crossover study to evaluate visual acuity.
- Trial name
- NCT07174596
- Testing
- B+L Infuse spherical soft contact lenses, J&J ACUVUE OASYS 1-Day spherical soft contact lenses
- Where
- 4 sites in United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract
Assesment of Intermediate Vision After BIL Cataract Surgery
The goal of this observational study is to learn about the intermediate and near vision in patiënts who underwent cataract surgery with a specific technique, called "bag in the lens".
- Trial name
- NCT06364761
- Testing
- Bag in the lens cataract surgery
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Aphakia, Cataract
Registry Study on Intraocular Lenses Manufactured by Teleon Surgical B.V.
This is a retrospective, observational (Registry) study aiming to collect safety and performance data on the use of intraocular lenses (IOLs) manufactured by Teleon Surgical B.V. according to routine practice.
- Conditions
- Aphakia, Cataract, Clear Lens Exchange, Refractive Lens Exchange
- Trial name
- NCT05290870
- Testing
- Posterior-chamber intraocular lens
- Where
- Netherlands
- Volunteers
- 2,183 people
- Sponsor
- Teleon Surgical B.V.
Cataract, Refractive Lens Exchange
Visual Performance of Patients Implanted With a Multifocal IOL
The goal of this clinical trial is to learn about the visual performance of a new multifocal intra-ocular lens in patients presenting for cataract or refractive lens exchange surgery.
- Trial name
- VISUAL (NCT06111222)
- Testing
- AT ELANA
- Where
- 3 sites in Germany, Spain
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Carl Zeiss Meditec AG
Astigmatism
Evaluating and Improving Functional Driving Vision of Patients With Astigmatism: Phase 3
It is a common clinical practice to leave small amounts of astigmatism uncorrected in contact lens wearers. Therefore, some drivers who have astigmatism and wear contact lenses may experience blur while driving.
- Trial name
- NCT02950545
- Testing
- Spherical Lenses, Toric Lenses
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Myopia, Progressive
Choroidal Response to Novel Spectacle Lens to Control Myopia Progression
Diurnal variations in the thickness of the choroid have been reported in the literature, and, more recently, the role of the choroid has been studied with respect to its role in myopia (near-sightedness) progression.
- Trial name
- CHERRY (NCT03818880)
- Testing
- Novel spectacle lens design
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- SightGlass Vision, Inc.
Myopia
A Two-Week Crossover Dispensing Evaluation Of Orion Daily Wear Soft Contact Lens
The primary objective of the study is to evaluate the clinical performance of test lens (Orion) in comparison with control lens (Gemini) over a period of two weeks of wear.
- Trial name
- NCT04585646
- Testing
- Orion daily disposable contact lens, Gemini daily disposable contact lens
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Atropine and Spectacle Combination Treatment (ASPECT): 12-month Results of a Randomized Clinical Trial for Myopia Control
Phase IV clinical trial to evaluate whether there is a significant difference in the control of myopia progression in myopic children treated with 0.025% atropine and DIMS spectacle lenses compared to 0.025% atropine and single…
- Trial name
- ASPECT (NCT06431841)
- Testing
- Atropine 0,025%, DIMS Lenses, Monofocal lenses
- Where
- Spain
- Volunteers
- 111 people
- Sponsor
- Hospital San Carlos, Madrid
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