Clinical trials: Lenses
Cataract Senile, Pseudophakia
Tecnis Eyhance Versus Rayner RayOne Study
Cataract surgery involves replacing milky lens with a plastic intraocular lens. This plastic lens can be either monofocal (fixates for distance or near without glasses), extended depth of focus (EDOF)(fixates for intermediate and…
- Trial name
- NCT04175951
- Testing
- Intraocular lens
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brighton and Sussex University Hospitals NHS Trust
Cataract
Safety and Efficacy of OMS302 in Subjects Undergoing Unilateral Cataract Extraction With Lens Replacement (CELR)
The purpose of this study is to determine whether the use of OMS302 (the study drug) in individuals undergoing Cataract Extraction with Lens Replacement (CELR) surgery is safe and effective at maintaining an adequately dilated…
- Trial name
- NCT01193127
- Testing
- OMS302 Solution, OMS302 Mydriatic Solution, OMS302 Anti-inflammatory Solution
- Where
- 24 sites in United States
- Volunteers
- 223 people
- Sponsor
- Omeros Corporation
Dry Eye Disease (DED), Cataract
Impact of DED on the Accuracy of Preoperative Keratometry Values in the Calculation of IOL Power for Cataract Surgery.
This study looks at how dry eye disease can affect important eye measurements needed before cataract surgery. These measurements guide us in choosing the right artificial lens to implant, which is essential for achieving clear…
- Trial name
- NCT06989827
- Testing
- Preservative free artificial tear
- Where
- Croatia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Sestre Milosrdnice
Cataract Congenital
Multifocal vs Monofocal IOL in Congenital Cataract Surgery
The aim of this study is to evaluate long-term outcome after congenital cataract surgery comparing results achieved with multifocal and monofocal IOLs.
- Trial name
- NCT04872829
- Testing
- cataract surgery
- Volunteers
- 43 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Ocular Hypertension
The Effect of a Scleral Lens on the Anterior Chamber Depth and Minimum Rim Width
The purpose of this study is to evaluate the use of two instruments to measure changes in two ocular structures: 1) the anterior chamber depth (ACD) - measured using low coherence optical biometry, and 2) minimum rim width of the…
- Trial name
- NCT03926975
- Testing
- Scleral Lens, No lens
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Houston
Glaucoma, Cataract
Observational Study to Evaluate Long Term Outcomes for Ocular Hypertension and Glaucoma Patients Treated With the SpyGlass Bimatoprost Implant System / IOL Combination
The goal of this clinical trial is to further observe and learn if the SpyGlass Pharma Bimatoprost Implant System / IOL Combination works to treat cataracts and either ocular hypertension or glaucoma.
- Conditions
- Glaucoma, Cataract, Ocular Hypertension
- Trial name
- NCT07154810
- Where
- Honduras
- Volunteers
- 23 people
- Sponsor
- SpyGlass Pharma, Inc.
Laparoscopic Surgical Procedures
Nano-Ceramic Coating for Laparoscope Lens
The investigator tests the effectiveness of nano-ceramic coating when applied (painted) on laparoscope lens to protect it from fogging or smearing during laparoscopic operations
- Trial name
- NCT03704259
- Testing
- Ceramic coating
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- Zagazig University
Myopia
Overall Performance of a 1-day Silicone Hydrogel Lens When Habitual Soft Lens Wearers Are Refit
The objective of the study is to compare the overall subjective comfort profile over 8 hours of lens wear in two groups of habitual soft contact lens wearers (daily disposable hydrogel lenses and frequent replacement lenses) when…
- Trial name
- NCT02588573
- Testing
- etafilcon A (control), somofilcon A (test)
- Where
- 2 sites in Canada
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataract
Clinical Endpoint Study of Nepafenac 0.3% Opthalmic Suspension
A randomized, multicenter, double masked, placebo controlled, parallel group, bioequivalence study to evaluate the clinical equivalence and safety of Nepafenac 0.3% ophthalmic suspension (manufactured by Indoco remedies Ltd.
- Trial name
- NCT03499873
- Testing
- Nepafenac 0.3% Oph Susp, Nepafenac 0.3% Oph Susp (reference)
- Where
- United States
- Volunteers
- 448 people
- Sponsor
- Actavis Inc.
Small Pupil, Cataract
Efficacy of the Canabrava/s Pupil Expansion Device in Cataract Surgery With Small Pupils: The First 30 Cases
To evaluate the intraoperative stability, safety and overall efficacy of the Canabrava Ring (AJL - SPAIN) when used to expand pupils with less diameter than 5 mm and pupils with sphincter synechiae.
- Trial name
- NCT03206983
- Testing
- Cana's Ring
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Santa Casa de Misericórdia de Belo Horizonte
Aphakia
Intraocular Position of Secondary Iris-Fixated IOLs in Aphakic Eyes
The purpose of this study is to evaluate the intraocular stability and safety of secondary iris-fixated IOLs in aphakic patients.
- Trial name
- NCT00773266
- Where
- Germany
- Volunteers
- 16 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Inflammation, Pain
Efficacy and Safety of XG-102 in Reduction of Post-cataract Surgery Intraocular Inflammation
The purpose of this study is to evaluate the clinical efficacy and safety of XG-102 (900µg) compared to vehicle in the treatment of subjects with inflammation and pain following cataract surgery.
- Conditions
- Inflammation, Pain, Cataract
- Trial name
- NCT02235272
- Testing
- XG-102
- Where
- United States
- Volunteers
- 339 people
- Sponsor
- Xigen SA
Glaucoma Eye, Cataract
Bulbicam Validation on Glaucoma- and Cataract Patients
The aim is to investigate repeatability and stability of the six OTH-related Bulbicam tests in patients suffering from Glaucoma (GLA), b) Cataract (CAT) and matched healthy controls (HC).
- Trial name
- NCT05449041
- Testing
- Bulbicam
- Where
- Norway
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Meddoc
Aphakia, Astigmatism
Clareon TruPlus Study
The purpose of this research study is to generate safety and performance data for Clareon TruPlus Monofocal Intraocular Lenses (IOLs).
- Trial name
- NCT07502456
- Testing
- Clareon TruPlus Monofocal Non-Toric IOL, Clareon TruPlus Monofocal Toric IOL, Phacoemulsification
- Where
- 5 sites in United States
- Volunteers
- 185 people
- Sponsor
- Alcon Research
Glaucoma
Pilocarpine Use After Kahook Goniotomy
The goal of this study is to determine whether using pilocarpine provides added benefit to the success of combined cataract + Kahook Dual Blade (KDB) surgery.
- Trial name
- PAACK (NCT03933631)
- Testing
- Pilocarpine, Prednisolone, Ofloxacin
- Where
- 2 sites in United States
- Volunteers
- 142 people
- Sponsor
- Montefiore Medical Center
Myopic Astigmatism
STAAR Visian Toric ICL Post-Approval Study
The objective of this study is to evaluate the long term (i.e. 24 months) clinical performance of the Visian® Toric Implantable Collamer® Lens (ICL).
- Trial name
- TICL-PAS (NCT04516772)
- Testing
- Visian TICL
- Where
- 8 sites in United States
- Volunteers
- 125 people
- Sponsor
- Staar Surgical Company
Age-related Cataract
Effective Lens Position After Cataract Surgery
Cataract patients were implanted with different types of intraocular lenses for grouping. SSOCT scanning was used to measure ELP and optometry.
- Trial name
- NCT04443101
- Testing
- different types of intracular lens
- Where
- 2 sites in China
- Volunteers
- 300 people
- Sponsor
- Wenzhou Medical University
Cataracts
Comparison of the Effectiveness of Povidone-iodine in Reducing Conjunctival Bacterial Load Prior to Cataract Surgery in Patients Treated With a Lidocaine Gel Dilating Formulation Versus Eye Drops: A Randomized Controlled Trial
The eye contains a lens that focuses light. A clouding of the lens is known as a cataract. Cataracts decrease vision. The treatment for cataracts is cataract surgery.
- Trial name
- NCT01898728
- Testing
- topical povidone-iodine after premedication with topical liquid eye drops, topical povidone-iodine after premedication with topical gel
- Where
- Canada
- Volunteers
- 101 people
- Sponsor
- McMaster University
Absence of Capsule Support, Aphakia
Clinical Observation of the Transscleral Suture Fixation of Posterior Chamber Intraocular Lens in Eyes With Inadequate Capsule Support
To present the follow-up outcomes of transscleral suture fixation of posterior chamber intraocular lens (PCIOL) in eyes with inadequate capsule support.
- Trial name
- NCT03817151
- Testing
- posterior chamber intraocular lens implantation
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Presbyopia
1-Week Dispensing Evaluation of Kalifilcon A Daily Disposable Multifocal Compared to Ultra for Presbyopia
Experienced soft contact lens wearing subjects will be enrolled in this 1-week, confirmatory, randomized, bilateral, 2-way crossover, double masked (subject and investigator), repeated measures, dispensing study.
- Trial name
- NCT05325931
- Testing
- kalifilcon A Daily Disposable Multifocal, samfilcon A for Presbyopia
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
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