Clinical trials: Lenses
Myopia
Non-Dispensing Evaluation of an Investigational Galyfilcon A Soft Contact Lens
The purpose of this investigation is to compare the fit characteristics and vision attributes of an investigational Galyfilcon A contact lens and an approved Galyfilcon A contact lens.
- Trial name
- NCT01054807
- Testing
- Galyfilcon A Habitual Lens, Galyfilcon A 8.7 BC (Investigational), Galyfilcon A 8.3 BC (Investigational)
- Where
- Australia
- Volunteers
- 32 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract
Postoperative Rotational Dynamics of Three Toric Intraocular Lens Designs
This prospective comparative cohort study evaluates and compares postoperative rotational stability and time-course dynamics of three commercially available toric intraocular lenses (TECNIS Toric II [ZCU], AcrySof IQ Toric, and…
- Trial name
- 3 TORIC ROTATE (NCT07453992)
- Testing
- TECNIS Toric II (ZCU), AcrySof IQ Toric, AT TORBI 709M
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Jin Yang
Glaucoma, Cataract
Evaluation of Microinvasive Glaucoma Surgery: MINIject® Versus Hydrus® Microstent in Combination With Cataract Surgery
The study aims to investigate postoperative outcomes after two different MIGS implants (MINIject or Hydrus) in combination with cataract surgery for patients with glaucoma.
- Trial name
- MINHY (NCT06844292)
- Testing
- MINIject with Cataract Surgery, Hydrus Microstent with Cataract Surgery
- Where
- Austria
- Volunteers
- 152 people
- Sponsor
- Medical University of Graz
Vision Correction
A Non-dispensing Fit Evaluation of Investigational Limbal Ring Soft Contact Lenses With Polyvinylpyrrolidone (PVP) in Asian Eyes
The purpose of this clinical trial is to compare the overall lens fit acceptance of two different soft contact lenses in an Asian population.
- Trial name
- NCT02036320
- Testing
- etafilcon A
- Where
- 7 sites in United States, Canada
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Ophthalmic Compatibility During Seven Days of Continuous Wear of Silicone Hydrogel Lenses
The purpose of this study is to assess the ophthalmic compatibility of three different silicone hydrogel lenses worn on an overnight basis for six nights.
- Trial name
- QUINCE (NCT00934102)
- Testing
- Narafilcon A contact lens, Lotrafilcon A contact lens, Galyfilcon A contact lens
- Where
- Canada
- Volunteers
- 57 people
- Sponsor
- CIBA VISION
Myopia, Keratoconus
Assessment of Corneal Biomechanical Properties Using Corvis ST and ECD Following LASIK, PRK, CXL, Veriflex IOL and Implantable Collamer Lens
To evaluate corneal biomechanical changes using the Corvis ST and ECD in patients who have under-gone LASIK, PRK, corneal cross-linking (CXL), Veriflex IOL and ICL.
- Conditions
- Myopia, Keratoconus, Refractive Surgery
- Trial name
- NCT06818461
- Testing
- Corvis St Before and after lasik, PRK, CXL, Veriflex IOL and ICL
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Neck Pain
The Impact of Lenses on Musculoskeletal and Visual Complaints in VDU Workers With Neck Complaints
The aim of this study is to investigate the impact of wearing visual display units (VDU) lenses versus progressive lenses on musculoskeletal and visual complaints in VDU workers with work related neck complaints.
- Trial name
- NCT02656953
- Testing
- VDU lenses (Zeiss® Officelens Plus), Progressive lenses (Zeiss® Multifocal Precision Plus)
- Volunteers
- 40 people
- Sponsor
- University Ghent
Cataract
Revised Capsular Polishing and Its Impact on the Positioning of the Intraocular Lens and Visual Quality Following Femtosecond Laser-assisted Cataract Surgery
This study aims to investigate the impact of improved capsular polishing on the long-term stability of effective lens position (ELP) and visual quality in patients following femtosecond laser-assisted cataract surgery combined…
- Trial name
- ELPVQFLACS (NCT06517095)
- Testing
- improved capsular polishing, the conventional I/A polishing
- Where
- China
- Sponsor
- Xi'an People's Hospital (Xi'an Fourth Hospital)
Refractive Error, Myopia
Silicone Hydrogel Contact Lenses on Low Astigmatism in Japan
This study seeks to evaluate the clinical performance of a recently released contact lens designed to correct astigmatism to an established contact lens that has historically been used in these patients.
- Conditions
- Refractive Error, Myopia, Astigmatism
- Trial name
- NCT00639353
- Testing
- senofilcon A toric soft contact lens, senofilcon A sphere soft contact lens
- Where
- 10 sites in Japan
- Volunteers
- 102 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Visual Acuity
Changes in Inflammatory Biomarkers When Symptomatic Contact Lens Wearers Are Refit in Acuvue Oasys 1-Day Lenses
This is a 5-Visit, single-arm, single-site, subject masked, dispensing trial to evaluate contact lens discomfort and inflammatory biomarker expression.
- Trial name
- NCT05120128
- Testing
- Acuvue® Oasys 1-Day
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract
Guangdong Uptake of Surgery Trial
The purpose of this study is: 1. To determine whether an educational intervention designed based on studies in the area is effective in increasing acceptance of surgery and presentation to the hospital, when adjusting for a…
- Trial name
- GUSTO (NCT01123928)
- Testing
- Video and counseling for cataract patients
- Where
- China
- Volunteers
- 434 people
- Sponsor
- Sun Yat-sen University
Measurement of the Elasticity of the Anterior Eye Segment
A Pilot Study to Test the Safety and Feasibility of a Brillouin Ocular Analyzer
A Brillouin ocular analyzer uses a low-power near infrared laser light to probe the viscoelastic properties of the cornea and crystalline lens in the eye.
- Trial name
- Brillouin I (NCT01775007)
- Testing
- Brillouin Ocular Analyser
- Where
- 2 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Myopia
Daytime Corneal Swelling During Wear of Narafilcon B Lenses
The purpose of this research is to measure daytime open-eye response to wearing of narafilcon B lenses.
- Trial name
- NCT01444287
- Testing
- narafilcon B, Polymacon, Lotrafilcon A
- Where
- Australia
- Volunteers
- 22 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract
Evaluation of Aqueous Humor DEL-1 and IL-17 Levels in Diabetic Cataract Patients
By comparing DEL-1 and IL-17 levels in the aqueous humor of diabetic cataract patients with the aqueous humor of non-diabetic patients, we aim to understand the biochemical effects of diabetes-related inflammatory processes in…
- Trial name
- DEL-1 and IL-1 (NCT06995131)
- Testing
- Observational Study Procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Uşak University
Glaucoma, Diabetic Retinopathy
Providing Financial Incentives to Improve Adherence to Referral Eye Care Visits
Glaucoma is a blinding eye disease increasingly common in older adults, particularly in African Americans, and often diagnosed late in the disease course.
- Conditions
- Glaucoma, Diabetic Retinopathy, Refractive Errors, Cataract
- Trial name
- AL-SIGHT (NCT04328207)
- Testing
- No Financial Incentive, Financial Incentive
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Intraocular Lens
Long-term Comparative Analysis of Visual Outcomes With 3 Intraocular Lenses: Monofocal, Trifocal and Accommodating
To compare visual outcomes, contrast sensitivity, glare occurrence, incidence of posterior capsule opacification (PCO) and subjective satisfaction in patients implanted with trifocal, accommodating and monofocal lens in long term…
- Trial name
- NCT05041881
- Testing
- Trifocal lens AT LISA TRI, Zeiss, Accommodating Tetraflex HD lens, Lenstec inc., Monofocal lens, Softec HD
- Where
- 2 sites in Czechia, Slovakia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Visual Acuity
Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Myopic Population; Part 2
This is a 6-visit, subject-masked, multi-site, 2×3 crossover dispensing trial that will last approximately 2 - 4 months.
- Trial name
- NCT04615507
- Testing
- JJVC Investigational Multifocal Contact Lens, Dailies Total 1® Multifocal Contact Lens
- Where
- 6 sites in United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Aphakia
Evaluation of the FluidVision Accommodating Intraocular Lens (AIOL) With an Improved Injector System
The purpose of this study is to evaluate the clinical outcomes of an investigational IOL in patients undergoing cataract extraction and intraocular lens implantation using an improved injector system.
- Trial name
- NCT02418871
- Testing
- FluidVision AIOL, Cataract surgery
- Where
- 5 sites in Hungary, South Africa
- Volunteers
- 53 people
- Sponsor
- PowerVision
Cataract
Caffeine and Cataract After Pars Plana Vitrectomy
Assessment of cataract development in patients with regular caffeine consumption and those without caffeine consumption after pars plana vitrectomy.
- Trial name
- NCT06358664
- Testing
- Pars plana vitrectomy
- Where
- Austria
- Volunteers
- 74 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Patients Who Have Bilateral NanoFlex Implantation at Least 3 Months Previously
Evaluation of Visual Outcomes of Monovision Patients Bilaterally Implanted With Nanoflex Intraocular Lenses
The purpose of this study is to look at how well you see the Nanoflex Intraocular lens placed in your eye.
- Trial name
- NCT01279122
- Testing
- Nanoflex IOL
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
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