Clinical trials: Lenses
Cataract, Presbyopia
Visual Results of the Acrysof IQ Vivity Toric Extended Vision Intraocular Lens
The main goal of this study is to evaluate real-world visual outcomes, rotational stability, and patient reported visual disturbances with a non-diffractive extended vision presbyopia and astigmatism correcting intraocular lens…
- Conditions
- Cataract, Presbyopia, Corneal Astigmatism
- Trial name
- NCT04652037
- Testing
- Acrysof IQ Vivity Toric Extended Vision Intraocular Lens Implantation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
POCD - Postoperative Cognitive Dysfunction
Cognitive Dysfunction After Cataract Surgery
Cataract surgery is commonly performed in elderly patients who are at high risk for developing postoperative cognitive dysfunction.
- Trial name
- NCT04730596
- Testing
- Ketamine, Dexmedetomidine, Normal saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Cataract
Comparison of a New EDOF-IOL With a Standard-EDOF-IOL
Comparison of the new extended depth of focus (EDOF) intraocular lens (IOL) ARTIS ACTIVE, which is designed as a twinset of IOLs, with the standard EDOF IOL AT Lara .
- Trial name
- NCT03921762
- Testing
- Cataract surgery with Artis Active IOLs, Cataract surgery with AT Lara IOLs
- Where
- Austria
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Glaucoma
Smart Soft Contact Lenses for Monitoring Glaucoma
This study is exploring the effectiveness and safety of soft contact lenses with embedded sensors, called smart contact lenses. Smart contact lenses are used to measure the pressure inside the eye.
- Trial name
- NCT07224542
- Testing
- Bare Contact Lens, Experimental Smart Contact Lens, Commercially available smart contact lens
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Indiana University
Myopia
One Month Performance Comparison Between Two Commercially Available Silicone Hydrogel Lenses
The purpose of this study is to compare the performance of two commercially marketed contact lenses when worn for up to one month in a daily wear modality.
- Trial name
- NCT01300741
- Testing
- Lotrafilcon B contact lens (AIR OPTIX® AQUA), Galyfilcon A contact lens (ACUVUE® ADVANCE® Plus), Contact lens solution (Clear Care®)
- Volunteers
- 75 people
- Sponsor
- CIBA VISION
Contact Lens Solutions
Evaluation of a Multi-Purpose Solution
This study evaluates a multi-purpose solution when used on a daily wear basis by currently adapted soft contact lens wearers.
- Trial name
- NCT00710879
- Testing
- Bausch & Lomb Multi-Purpose Solution
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia
A Product Performance Evaluation of a Novel Contact Lens for Daily Disposable Use
Evaluation of the clinical performance of a novel Bausch \& Lomb daily disposable contact lens when compared to the currently marketed Bausch \& Lomb SofLens® daily disposable contact lenses and the currently marketed Johnson and…
- Trial name
- NCT00784641
- Testing
- Novel Bausch & Lomb daily disposable contact lenses, Bausch & Lomb SofLens daily disposable contact lenses., Johnson and Johnson 1-Day Acuvue Moist contact lenses
- Where
- United States
- Volunteers
- 567 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Refractive Errors
Clinical Evaluation of Two Monthly Contact Lenses
The purpose of this study is to explore overall vision with BIOFINITY® ENERGYS™ contact lenses as compared to BIOFINITY® contact lenses after one week of wear.
- Trial name
- NCT03459131
- Testing
- Comfilcon A with Digital Zone Optics™ contact lenses, Comfilcon A contact lenses
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Alcon Research
Cataract, Dry Eye
Corneal Sensation and Incidence of Dry Eye Post Refractive Cataract Extraction With FemtoSecond Laser
The study objective is to assess changes in corneal sensation and dry eye signs and symptoms following cataract extraction/femtosecond arcuate relaxing incisions.
- Trial name
- NCT01441895
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ophthalmic Consultants of Long Island
Aphakia, Corneal Astigmatism
Clareon Toric Study (T2-T9)
The purpose of this post-market study is to describe the long-term safety and performance of Clareon Toric Intraocular Lenses (IOLs).
- Trial name
- NCT06285695
- Testing
- Clareon Toric IOL, Cataract surgery
- Where
- 6 sites in Canada
- Volunteers
- 129 people
- Sponsor
- Alcon Research
Dry Eye, Contact Lens Complication
Effects of Supplementation With PUFAs and Antioxidants for Contact Lens Discomfort
HydroEye® is a dietary omega 3 fatty acid supplement that contains both EPA and DHA, as well as GLA and ALA in the form of black currant seed oil.
- Trial name
- NCT04163328
- Testing
- HydroEye®
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Alabama at Birmingham
Refractive Error, Cataract
Vision Measured by the Vimetrics CVA Compared With Chart Testing Under Similar Luminance and Contrast Conditions
Purpose of The Study: The purpose of this study is the following: A)To gather age-related normative visual acuity data for the Vimetrics Central Vision Analyzer (CVA, Vimetrics, LLC, Media, Pa) B)To gather visual acuity data for…
- Conditions
- Refractive Error, Cataract, Maculopathy
- Trial name
- NCT02028351
- Where
- 2 sites in United States, Austria
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sinclair Technologies, LLC
Meibomian Gland Dysfunction, Dry Eye Syndromes
Meibomian Gland Dysfunction Management With ZEST Protocol
The purpose of this study is to investigate if cleaning the eyelid margin with the ZEST protocol (Zocular Eyelid System Treatment) in patients intolerant to contact lens wear consequent to Meibomian gland dysfunction (MGD) will…
- Conditions
- Meibomian Gland Dysfunction, Dry Eye Syndromes, Ocular Surface Disease
- Trial name
- NCT03968731
- Testing
- Zocular Eyelid System Treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of the Incarnate Word
Cataract, Uveitis
Safety and Efficacy of a Heparin-Coated Intraocular Lens in Uveitis
To investigate the safety and efficacy of a heparin surface-modified intraocular lens in patients with uveitis undergoing cataract surgery.
- Trial name
- NCT00000119
- Testing
- Heparin Surface-Modified Intraocular Lens
- Where
- United States
- Sponsor
- National Eye Institute (NEI)
Cataract
Satisfaction & Spectacle Independence With ReSTOR 2.5 & ReSTOR 3.0 IOLs
Patients implanted with the ReSTOR 2.5 multifocal IOL in the dominant eye and the ReSTOR 3.0 in the non-dominant eye have overall satisfaction and spectacle independence at least comparable to that with bilateral implantation of…
- Trial name
- NCT03073681
- Testing
- Survey
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- MDbackline, LLC
Visual Acuity
Evaluation of Acuvue Oasys 1-Day Contact Lenses in New Wearers
This is a multi-site, bilateral, dispensing, non-randomized, uncontrolled, unmasked, single arm study to evaluate visual acuity in neophytes.
- Trial name
- NCT06333613
- Testing
- ACUVUE OASYS® 1-DAY with HydraLuxe™ TECHNOLOGY (AO1D)
- Where
- 5 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Diabetes, Cataract
Healing of Corneal Incision After Cataract Surgery in Diabetic Patients
The objective of this observational study was to understand the healing of corneal incision after cataract surgery in diabetic patients and its influencing factors.
- Trial name
- NCT07076420
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Zhongnan Hospital
Myopic Progression
Effects of Different Designs of Orthokeratology Lens on Myopia Control and Visual Quality
This study was aimed to evaluate the effects of different Orthokeratology，including the size of central optical zone and the height of peripheral reverse curve, on myopia control and visual quality.
- Trial name
- NCT05192824
- Testing
- Orthokeratology lens
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Subluxation
A Novel Approach to Lens Subluxation
Evaluating new technique for treating patients with subluxation using specific laser type and new 6-0 proline fixating novel technique for the capsular bag
- Trial name
- NCT06773273
- Testing
- CapsuLaser-Assisted Capsulorhexis and Flanged Prolene Suture
- Where
- Saudi Arabia
- Volunteers
- 15 people
- Sponsor
- Zagazig University
Cataracts
Evaluation of Real-World Data on the Performance of the TECNIS Odyssey™ IOL
Retrospective collection of data from medical records, multicenter, post-market clinical follow-up study.
- Trial name
- NCT05991960
- Testing
- Intervention
- Where
- 12 sites in United States
- Volunteers
- 96 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
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