Clinical trials: Lenses
Visual Acuity
Evaluation of Astigmatic Contact Lenses
Randomized, double-masked, 5-visit, bilateral dispensing, parallel group study to demonstrate that the investigational contact lens meets the design requirements related to corneal staining, lens fit, visual acuity and rotational…
- Trial name
- NCT03086447
- Testing
- Investigational Contact Lens, Marketed Contact Lens
- Where
- 17 sites in United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract
Clinical Evaluation of the Next Generation Phaco System
This study is a prospective, open-label clinical study of the VERITAS Vision System. The study will be conducted at up to three sites, with minimum 55 eyes and up to 150 eyes to be treated.
- Trial name
- ALPINE (NCT04332640)
- Testing
- VERITAS Vision System
- Where
- 2 sites in United States, El Salvador
- Volunteers
- 79 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Myopia
Fitting Evaluation of Hydrogel and Silicone Hydrogel Spherical Contact Lenses
This study aims to compare the short-term clinical performance of the three contact lenses (Methafilcon A IV, Ocufilcon B 1-day and Omafilcon A 1-day daily disposable).
- Trial name
- NCT03235115
- Testing
- Methafilcon A IV, Ocufilcon B, Omafilcon A
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Astigmatism Bilateral
Evaluation of Wear Experience With a Weekly Replacement Soft Contact Lens in Neophyte Lens Wearers With Astigmatism
This open-label study is of adults with astigmatism who have never worn contact lenses. Subjects will be fit into a one week planned-replacement contact lenses and will wear lenses for approximately 3 weeks.
- Trial name
- NCT06751225
- Testing
- One week replacement soft contact lenses
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Fuchs Endothelial Corneal Dystrophy, Cataract (Post-operative Cataract Surgery Follow-up)
Postoperative CCT in FECD vs. Non-FECD
This single-centre, prospective, controlled, non-interventional observational clinical study aims to characterize early postoperative corneal thickness behaviour after routine phacoemulsification cataract surgery in eyes with…
- Trial name
- NCT07731945
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Vienna Hospital Association
Cataract
Randomized Contralateral Clinical Trial With Single-piece (SN60WF) vs. Three Piece (MA60AC) AcrySof Intraocular Lenses (IOLs) on Development of Posterior Chamber Opacification (PCO).
Randomized contralateral clinical trial with single piece (Model SN60WF) vs. three piece (Model MA60AC) AcrySof Intraocular Lenses (IOLs) on development of Posterior Chamber Opacifiation (PCO).
- Trial name
- NCT00758745
- Testing
- Model SN60WF, Model MA60AC
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Alcon Research
Cataract and IOL Surgery
Clareon PanOptix Versus AcrySof PanOptix : Prospective Study Comparing Contrast Sensitivity
Retrospective, comparative, interventional, randomized, single-center study, contralateral (the patient's 2 eyes will be implanted: 1 CPO and the other APO) Patients presenting for cataract surgery with a request for presbyopia…
- Trial name
- CLAYRE (NCT07158177)
- Testing
- Acrysof™ PanOptix™ toric or not, trifocal IOL CE marked, Alcon company., Clareon Panoptix
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Myopia, Refractive Errors
Peripheral Defocus Profile of Multifocal Minus Contact Lenses
Purpose: Numerous studies have proven that emmetropization in young animals including humans is regulated by visual input. It has long been hypothesized that peripheral myopic defocus may act as a stop signal to reduce myopia…
- Conditions
- Myopia, Refractive Errors, Contact Lens
- Trial name
- NCT06335212
- Testing
- Single vision and multifocal contact lenses
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Cataract
Visual Function After Implantation of Bilateral AcrySof ReSTOR Aspheric +3
A prospective evaluation of the visual parameters in a series of patients bilaterally implanted with AcrySof ReSTOR +3 Intraocular Lens (IOL).
- Trial name
- NCT00719732
- Testing
- ReSTOR
- Where
- United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Myopia
A Study to Evaluate a New Silicone Hydrogel Contact Lens
The objective of this study is to determine the clinical feasibility and to evaluate the product performance of investigational contact lenses.
- Trial name
- NCT01309893
- Testing
- Investigational Lens, Air Optix Aqua lens
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Astigmatism
Clinical Evaluation of Two Monthly Replacement Silicone Hydrogel Contact Lenses
The purpose of this study is to evaluate differences in the comfort at the end of the month between Air Optix® lenses versus Biofinity® lenses in habitual daily wear symptomatic soft contact lens wearers.
- Trial name
- NCT01629693
- Testing
- Lotrafilcon B contact lenses, Comfilcon A contact lenses
- Volunteers
- 398 people
- Sponsor
- Alcon Research
Cataract
Comfort Operative Ocular Light Study
Digital 3D microscopes require less light and may be more comfortable for patients requiring cataract surgery under topical anesthesia compared to conventional microscopes.
- Trial name
- COOL (NCT05085314)
- Testing
- Ngenuity digital 3D microscope, Conventional microscope
- Where
- 2 sites in France
- Volunteers
- 134 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Retinal Detachment, Macular Pucker
Zeiss RESIGHT Disposable Lenses Evaluation Study
To evaluate the intra-operative efficacy of a new intra-operative viewing device.
- Conditions
- Retinal Detachment, Macular Pucker, Macular Holes, Vitreomacular Traction
- Trial name
- RESIGHT (NCT05860985)
- Testing
- ZEISS disposable
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Lenses, Intraocular, Glaucoma Filtration Implants
Visual Function and Patient Satisfaction in Glaucoma or Ocular Hypertensive Patients Undergoing Simultaneous Cataract Surgery and i-Stent Implantation
New extended depth of focus intraocular lenses (IOLs) are being used in a broader spectrum of patients than trifocal IOLs. The purpose of this study is to evaluate visual improvement after cataract surgery in patients with…
- Trial name
- NCT05392738
- Testing
- I-Stent implantation
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Clínica Rementería
Visual Acuity
Non-Invasive Assessment of Contact Lens Performance During Use of a Digital Display
This is a two-arm, open-label, bilateral dispensing clinical investigation. Eligible subjects will proceed to either a low-sphere or high-sphere arm based on refraction measurements in the baseline assessment.
- Trial name
- NCT04869189
- Testing
- JJVC Marketed Contact Lens
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract Surgery, Cataract
Evaluation of Head-Mounted Spatial Computing and Three-Dimensional (3D) Visualization in Ocular Microsurgery: A Safety and Workflow Study
The purpose of this research is to evaluate the use of the research study device, the Apple Vision Pro head-mounted spatial computing display, with the Zeiss Artevo 850 digital microscope system, for the visualization during…
- Trial name
- NCT07301385
- Testing
- Apple Vision Pro (Head-Mounted Spatial Computing Display), Zeiss Artevo Digital Surgical Microscope
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Sharp HealthCare
Age-related Cataract
Metabo-lipidomics of the Ocular Surface for Cataract Surgery
Cataract is the world's leading cause of blindness, the treatment of which, exclusively surgical, offers excellent results in terms of visual recovery.
- Trial name
- CATARACTOMIQUE (NCT05802550)
- Testing
- Ocular Surface Disease Index, Interferometry, Oxford score
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Tours
Cataract
Postoperative Discomfort and Ocular Redness Following Phacoemulsification Surgery
Primary objective of the study is the assessment of the patients' discomfort and ocular redness following cataract extraction surgery by means of phacoemulsification and intraocular lens implantation.
- Trial name
- NCT02558218
- Testing
- Systane Ultra, tobradex quid (Standard)
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Democritus University of Thrace
Refractive Error
Initial Performance of a Modified Daily Disposable Contact Lens
The purpose of this study is to evaluate the incidence of ocular discomfort device-related adverse events with DAILIES TOTAL1® with UV Absorber (DT1 UV) contact lenses compared with current DAILIES TOTAL1® (DT1) contact lenses.
- Trial name
- NCT02694835
- Testing
- Delefilcon A contact lenses with UV Absorber, Delefilcon A contact lenses
- Volunteers
- 81 people
- Sponsor
- Alcon Research
Cataract
Evaluation of the Rotational Stability of the Monofocal SISA Implant Following Cataract Surgery
A good efficacy as well as good rotary stability is expected with the ocular implant.
- Trial name
- SISALens (NCT03356847)
- Testing
- Fitting of ocular implant
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
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