Clinical trials: Lenses
Scleral Lens Wearers
Efficacy of Scleral Contact Lenses for Daily Wear for Regular and Irregular Refractive Errors Compared to Habitually Worn Scleral Lenses
This study will be done with subjects who already habitually wear scleral contact lenses. The study lens is made with a material that is already widely available and has a new design.
- Trial name
- NCT02643095
- Testing
- scleral contact lens
- Volunteers
- 22 people
- Sponsor
- Jennifer Fogt
Cerebrotendinous Xanthomatosis (CTX)
Cerebrotendinous Xanthomatosis (CTX) Prevalence Study
Iiopathic bilateral cataracts occur in many children with Cerebrotendinous Xanthomatosis (CTX) so the opportunity to use contact with health care providers in connection with pediatric cataract evaluation and treatment is a…
- Trial name
- NCT02638220
- Where
- 44 sites in United States
- Volunteers
- 442 people
- Sponsor
- Travere Therapeutics, Inc.
Refractive Errors
Clinical Evaluation of a Daily Wear Monthly Replacement Silicone Hydrogel Lens
The purpose of this clinical study is to evaluate the safety and effectiveness of an investigational soft contact lens compared to a commercially available soft contact lens when worn for daily wear and replaced monthly.
- Trial name
- NCT04178720
- Testing
- Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
- Where
- 8 sites in United States
- Volunteers
- 119 people
- Sponsor
- Alcon Research
Eye Diseases, Postcataract Aphakia
Investigation of the Safety and Effectiveness of a Trifocal IOL
This study is a prospective, multicenter, randomized, double masked confirmatory trial comparing an investigational trifocal intraocular lens (IOL) and a commercially available monofocal IOL.
- Conditions
- Eye Diseases, Postcataract Aphakia, Cataract, Lens Opacities
- Trial name
- NCT04176965
- Testing
- FINEVISION HP IOL, Alcon AcrySof SN60AT
- Where
- 20 sites in United States
- Volunteers
- 539 people
- Sponsor
- Beaver-Visitec International, Inc.
Cataracts
Clinical Investigation of Healon EndoCoat Ophthalmic Viscosurgical Device (OVD)
Prospective, multicenter, paired-eye, randomized, subject/evaluator-masked clinical investigation of the experimental EndoCoat OVD versus the control EndoCoat OVD.
- Trial name
- NCT05575063
- Testing
- Investigational Healon Endocoat, Control Healon EndoCoat
- Where
- 8 sites in United States
- Volunteers
- 165 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Myopia, Refractive Error
DAILIES TOTAL1® Lens Centration in a Japanese Population
The purpose of this study is to compare the lens centration of DAILIES TOTAL1® (DT1) contact lenses to 1-DAY ACUVUE® Tru-Eye® (1DAVTE) contact lenses in a Japanese population after 7 ± 2 days of wearing of each product.
- Trial name
- NCT02252133
- Testing
- Delefilcon A contact lenses, Narafilcon A contact lenses
- Where
- Japan
- Volunteers
- 53 people
- Sponsor
- Alcon Research
Visual Acuity
Evaluation of a Daily Disposable Novel Multifocal Contact Lens in a Myopic Population; Part 2
This is a 6-visit, subject-masked, multi-site, 2×3 crossover dispensing trial that will last approximately 2 - 4 months.
- Trial name
- NCT04615507
- Testing
- JJVC Investigational Multifocal Contact Lens, Dailies Total 1® Multifocal Contact Lens
- Where
- 6 sites in United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataracts
A Clinical Outcome Study of Two Multifocal Intraocular Lenses (IOL) in Cataract Patients
The purpose of this study is to compare AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL in both eyes (bilateral implantation) to AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL in the dominant eye with AcrySof® IQ ReSTOR® +3.0 D Multifocal…
- Trial name
- NCT01684007
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0], AcrySof® IQ ReSTOR® +3.0 D Multifocal IOL Model SN6AD1
- Volunteers
- 112 people
- Sponsor
- Alcon Research
Cataract
Clinical Evaluation of the One-Piece Tecnis Multifocal Intraocular Lens (IOL)
The purpose of this study is to evaluate near vision of the One-Piece Tecnis Multifocal lens (ZMB00) vs. the One-piece Tecnis monofocal lens (ZCB00)and additionally evaluate general postoperative outcomes of the One-Piece Tecnis…
- Trial name
- NCT01210807
- Testing
- One-Piece Tecnis Multifocal IOL, One-Piece Tecnis monofocal IOL, Model ZCB00
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Functionality of Experimental Contact Lens
Ocular Adaptation and Visual Performance for Accommodative Contact Lens
Presbyopes (people who might have a significant loss of their ability to accommodate their crystalline lens in the eye) will be recruited to wear a test lens and perform typical clinical tests of visual acuity with different…
- Trial name
- ACL (NCT02923232)
- Testing
- Accommodative contact lens
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Pacific University
Refractive Ametropia
The Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses
The purpose of this study is to assess the clinical performance of two reusable silicone hydrogel contact lenses when worn on a daily wear basis.
- Trial name
- NCT05766787
- Testing
- Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
- Where
- 15 sites in United States
- Volunteers
- 190 people
- Sponsor
- Alcon Research
Refractive Errors
Clinical Performance Assessment of a Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lens
The purpose of this study is to obtain on-eye performance data to inform contact lens product development.
- Trial name
- NCT04055519
- Testing
- Lehfilcon A contact lenses, Comfilcon A contact lenses, Multi-purpose disinfection solution
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Alcon Research
Soft Contact Lenses, Myopia
DAILIES TOTAL1 Versus ACUVUE TruEye - Effects on the Biology of the Ocular Surface and Lid Margin
This is a prospective, single center, randomized, bilateral crossover, dispensing clinical trial to evaluate the effects of the water gradient lens, DAILIES TOTAL1, on the biology of corneal epithelium over two months of daily…
- Trial name
- TruEyeTotal1 (NCT02347631)
- Testing
- Soft Contact Lens - Daily Disposable Alcon Dailies Total 1 and ACUVUE TruEye, Soft Contact Lens - Acuvue TruEye and Alcon DAILIES TOTAL 1.
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Myopic Astigmatism
STAAR Visian Toric ICL Post-Approval Study
The objective of this study is to evaluate the long term (i.e. 24 months) clinical performance of the Visian® Toric Implantable Collamer® Lens (ICL).
- Trial name
- TICL-PAS (NCT04516772)
- Testing
- Visian TICL
- Where
- 8 sites in United States
- Volunteers
- 125 people
- Sponsor
- Staar Surgical Company
Cancer, Cataract
Evaluation of New or Worsening Lens Opacifications in Men With Non-metastatic Prostate Cancer Receiving Denosumab for Bone Loss
This is a phase 3, randomized, double-blind, placebo-controlled study to evaluate new or worsening lens opacifications in men with non-metastatic prostate cancer receiving denosumab for bone loss due to androgen deprivation…
- Conditions
- Cancer, Cataract, Low Bone Mineral Density, Osteopenia
- Trial name
- NCT00925600
- Testing
- Denosumab
- Where
- 172 sites in United States, Australia and 16 more
- Volunteers
- 769 people
- Sponsor
- Amgen
Cataract
Three Intraocular Lenses Designed to Improve Distance, Intermediate and Near Vision Following Lens Extraction
The objective of this study is to compare the contrast sensitivity, high and low contrast visual acuity (VA), glare meter outcomes, and subject satisfaction with three different FDA-approved intraocular lenses (IOLs) designed to…
- Trial name
- NCT01225952
- Testing
- Crystalens AO, ReSTOR 3.0, AMO Tecnis Multifocal
- Where
- Philippines
- Volunteers
- 93 people
- Sponsor
- Bausch & Lomb Incorporated
Astigmatism
Clinical Evaluation of Hydrogel and Silicone Hydrogel Daily Disposable Toric Contact Lenses
This study was to evaluate the patient subjective experiences of two daily disposable toric contact lenses.
- Trial name
- NCT05805085
- Testing
- Lens A, Lens B
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- CooperVision, Inc.
Refractive Errors
Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses
The purpose of this study is to assess the clinical performance of two reusable silicone hydrogel contact lenses when worn on a daily wear basis.
- Trial name
- NCT05431478
- Testing
- Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
- Where
- 5 sites in United States
- Volunteers
- 68 people
- Sponsor
- Alcon Research
Refractive Error
Clinical Comparison of Two Silicone-Hydrogel Contact Lenses
The objective of this study is to evaluate the clinical performance of two silicone-hydrogel contact lenses.
- Trial name
- NCT00762385
- Testing
- galyfilcon A, comfilcon A
- Volunteers
- 97 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract Bilateral, Presbyopia
Tecnis ZLB00 & Symfony Intraocular Lens Combination Outcomes
Current visual outcomes expectations of cataract patients are similar to those of refractive surgery patients. Their desire is to be spectacle independent for far, intermediate and near vision activities.
- Trial name
- NCT03771274
- Testing
- Tecnis ZLB00 & Symfony IOL
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Carolina Eyecare Physicians, LLC