Clinical trials: Lenses
Myopia
Evaluation of Comfilcon A and Senofilcon A Lenses
Evaluation of Comfilcon A and Senofilcon A Lenses
- Trial name
- NCT01695369
- Testing
- Senofilcon A; Comfilcon A, Comfilcon A; Senofilcon A
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- CooperVision, Inc.
Cataract
Bioavailability of Bimatoprost Ophthalmic Solution in Human Aqueous.
The purpose of this study is to assay human aqueous for bimatoprost and the presence of any metabolites, especially prostaglandin analogs.
- Trial name
- NCT00355446
- Testing
- Bimatoprost 0.03%
- Where
- 4 sites in United States
- Volunteers
- 48 people
- Sponsor
- Indiana University
IOL, Cataract
Post-Market Clinical Follow-Up Study on the Rotational Stability of an Intraocular Lens After Cataract Surgery
The goal of this post-market, prospective study at multiple clinics is to evaluate the rotational stability of the RayOne Model RAO800S non-toric monofocal intraocular lens with orientation marks in adult patients undergoing…
- Trial name
- NCT07099079
- Volunteers
- 92 people
- Sponsor
- Rayner Intraocular Lenses Limited
Cataract, Phacoemulsification
Intracameral Mydriasis Versus Topical Mydriasis in Cataract Surgery
The purpose is to determine if an intracameral solution of 0.2% tropicamide and 2% phenylephrine can dilate the pupil for cataract surgery as well as pre-operative topical 1% tropicamide and 5% phenylephrine.
- Conditions
- Cataract, Phacoemulsification, Mydriasis, Pseudoexfoliation Syndrome
- Trial name
- NCT00690222
- Testing
- Intracameral injection of mydriatic agent
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Nova Scotia Health Authority
Other Iris and Ciliary Body Disorders
Evaluation of Topical Anesthesia Alone Versus Combined With Intracameral LIdocaine 1%
General anesthesia may be non preferable in many patients undergoing Phakic IOL surgery, as most of the surgeries take 5-10 minutes at maximum.Traditionally, retrobulbar injections were performed deep into the orbit, but it is…
- Trial name
- NCT02215057
- Testing
- topical anesthesia, topical anesthesia plus intracameral lidocaine 1%
- Where
- Saudi Arabia
- Volunteers
- 45 people
- Sponsor
- Cairo University
Dry Eye, Dry Eye Syndromes
The Effect of a Pre-cataract Surgical Ocular Hygiene Regime on Microbial Load, Tear Osmolarity, Dry Eye, and Inflammatory Markers
This study assesses the impact of two differing ocular hygiene regimens prior to cataract surgery. The first regimen includes an omega-3 supplement and the second without, and both include an at-home lid wipe and cleansing eye…
- Conditions
- Dry Eye, Dry Eye Syndromes, Cataract
- Trial name
- NCT05990712
- Testing
- Omega-3, Trehalose, Zocular Eyelid System Treatment
- Where
- Canada
- Volunteers
- 68 people
- Sponsor
- Uptown Eye Specialists
Presbyopia, Pseudophakia
Pilocarpine and Brimonidine in Patients With Monofocal Lenses
The current study aims to assess the use of pilocarpine and brimonidine to improve near visual acuity in patietns with monofocal intraocular lenses.
- Trial name
- NCT03825081
- Testing
- Brimonidine, pilocarpine
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Myopia
Feasibility of a New Silicone Hydrogel Lens
The objective of this study is to determine the product feasibility of the investigational contact lens (Test) when compared to the currently marketed Acuvue Oasys contact lens (Control) and the Air Optix Aqua contact lens…
- Trial name
- NCT01131130
- Testing
- Investigational contact lens, Acuvue Oasys Contact Lens, Air Optix Aqua
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Bausch & Lomb Incorporated
Cataracts, Astigmatism
Post Approval Study of the AcrySof® IQ Toric Intraocular Lens (IOL) Models SN6AT6-SN6AT9
The purpose of this study is to evaluate the use of toric high cylinder power intraocular lenses in a larger population in clinical practice and assure the continued safety of these approved devices.
- Trial name
- NCT01601665
- Testing
- SN6AT6 Intraocular Lens, SN6AT7 Intraocular Lens, SN6AT8 Intraocular Lens
- Where
- United States
- Volunteers
- 477 people
- Sponsor
- Alcon Research
Cataract
Clinical Evaluation of the One-Piece Tecnis Multifocal Intraocular Lens (IOL)
The purpose of this study is to evaluate near vision of the One-Piece Tecnis Multifocal lens (ZMB00) vs. the One-piece Tecnis monofocal lens (ZCB00)and additionally evaluate general postoperative outcomes of the One-Piece Tecnis…
- Trial name
- NCT01210807
- Testing
- One-Piece Tecnis Multifocal IOL, One-Piece Tecnis monofocal IOL, Model ZCB00
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Refractive Error
On-Eye Evaluation of Contact Lens Rotation Marks
The purpose of this study was to select the size of the molded rotation mark for a new toric contact lens by comparing the visibility of various molded rotation marks.
- Trial name
- NCT02055404
- Testing
- Delefilcon A spherical contact lens with molded marks, Etafilcon A toric contact lens
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Cataract, Age Related Macular Degeneration
Polarization Perception in Health and Disease. Testing a New Sight Test
A study to assess the utility of human polarization pattern perception for the detection, diagnosis and monitoring of eye disease
- Conditions
- Cataract, Age Related Macular Degeneration, Pseudophakia, Macular Disease
- Trial name
- TaNSiT (NCT03823092)
- Testing
- polarization sensitivity
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- South Warwickshire NHS Foundation Trust
Dry Eye
Evaluation of Comfort of Ocular Lubricants in Symptomatic Contact Lens Wearers
The purpose of this study is to evaluate the ocular comfort of 3 ocular lubricants and a comparator.
- Trial name
- NCT05741216
- Testing
- OTF Ocular Lubricant, Ocular Lubricant
- Where
- 3 sites in Australia, Canada
- Volunteers
- 36 people
- Sponsor
- Alcon Research
Contact Lens Lubrication
A Study to Compare a New Eye Drop Formulation With Refresh Contacts®
This study will compare the safety and efficacy of a new carboxymethylcellulose based eye drop formula to Refresh Contacts® for lubricating and rewetting contact lenses.
- Trial name
- NCT01844388
- Testing
- carboxymethylcellulose based eye drop formula, carboxymethylcellulose sodium based eye drop solution
- Where
- United States
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- Allergan
Myopia, Accommodation
Dynamic Change in Accommodation After Wearing Multifocal Soft Contact Lenses for Myopia Control
The purpose of this study is to report the changes in accommodation, aberrations, and myopia in patients wearing multifocal soft contact lens for various durations. The study objectives are to: 1.
- Trial name
- NCT04763694
- Testing
- Multifocal soft contact lenses
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Amplitude of Pseudoaccommodation
Pseudoaccommodation of the Light Adjustable Lens: A Comparitive Study
Cataract surgery involves the removal of a cloudy natural lens, followed by the implantation of an artificial lens. The choice of lens implant helps determine what the vision will be like after surgery.
- Trial name
- NCT07176429
- Testing
- Measurement of refractive error and amplitude of pseudoaccommodation
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Helm Vision Group
Myopia
Clinical Evaluation of the Safety and Efficacy of Yung Sheng 55 % Color Contact Lens
This was a single group, open-label clinical study to assess the safety and efficacy of Yung Sheng 55% Color Contact Lens for vision correction.
- Trial name
- NCT06128486
- Testing
- Soft Contact Lens
- Volunteers
- 62 people
- Sponsor
- Yung Sheng Optical Co., Ltd.
Myopia, Child Myopia Progression
Effect of MiYOSMART iQ Spectacle Lenses on Myopia Progression in Children
This prospective, single-center study aims to evaluate the efficacy and safety of MiYOSMART iQ spectacle lenses with DIMS (Defocus Incorporated Multiple Segments) and Triple Enhanced Design (TED) technology in slowing myopia…
- Trial name
- NCT07387159
- Testing
- MiYOSMART iQ spectacle lenses
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- Hoya Lens Rus LLC
Cataract
Recommendations for Monitoring Clinical Experience Following Implantation of the AcrySof® Toric
To allow surgeons to obtain clinical experience on the postoperative uncorrected and best distance corrected visual acuities (UCVA and BDCVA) and corneal and refractive cylinder of the AcrySof Toric IOL.
- Trial name
- NCT00761488
- Testing
- AcrySof® Toric IOL
- Where
- United States
- Sponsor
- Alcon Research
Myopia
A Study to Evaluate the Product Performance of the PureVision®2 High Definition (HD) Contact Lens
The objective of this study is to evaluate the product performance of PureVision2 HD contact lenses.
- Trial name
- NCT01416142
- Testing
- PureVision2 HD contact lenses, Spectacles
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Bausch & Lomb Incorporated
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