Clinical trials: Lenses
Schlemm's Canal Occlusion
Observing the Morphology of Schlemm's Canal and Crystalline Lens in Different Age
The aim of this study is to quantify and observe the morphology of trabecular meshwork (TM), Schlemm's canal (SC), ciliary body and crystalline lens before and after cycloplegia in patients with different ages using swept-source…
- Trial name
- NCT04360161
- Testing
- swept-source optical coherence tomography
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Refractive Ametropia
Dispensing Evaluation of Subjective Comfort, Vision, and Handling of a New Lens Compared to a Marketed Lens
To evaluate and compare the performance of a new contact lens to a marketed contact lens.
- Trial name
- NCT01484054
- Testing
- etafilcon A with print and PVP for dark eyes (EAPVPDE), etafilcon A control lens (EADE)
- Where
- 6 sites in United States
- Volunteers
- 103 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Ocular Surface Disease
LK Scleral Lens for Patients With Intractable Ocular Surface Diseases
Scleral lenses have emerged as an efficacious treatment option for various types of intractable ocular surface diseases with many advantageous results.
- Trial name
- NCT04535388
- Testing
- LK scleral lens
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Postural Neck Pain, Postural Imbalance
Radiographic Head and Neck Positional Changes in Response to Usage of Low-powered Prismatic Lenses
This study aims to investigate the short-term modifications in head and neck positioning by usage of low-powered prismatic lenses in patients with Postural Deficiency Syndrome (PDS). A matched pair observation study was designed.
- Conditions
- Postural Neck Pain, Postural Imbalance, Postural Disorders
- Trial name
- NCT07532642
- Testing
- Prismatic low-powered lenses
- Where
- Portugal
- Volunteers
- 20 people
- Sponsor
- Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa
Cataract
Evaluation of Efficacy and Long-term Safety for the InFo - Instant Focus © Lens / PMCF
This is a monocentric, longitudinal, prospective, observational post-market follow-up study. 30 patients with a cataract will receive an InFo - Instant Focus © lens implant.
- Trial name
- INFOLO (NCT02841670)
- Testing
- InFo - Instant Focus (c) lens implantation
- Volunteers
- 30 people
- Sponsor
- SAV-IOL SA
Refractive Errors, Ametropia
Clinical Performance of Two Daily Disposable Toric Soft Contact Lenses
The purpose of this study is to compare the clinical performance of PRECISION1™ for Astigmatism (P1fA) contact lenses with 1-DAY ACUVUE MOIST® for ASTIGMATISM (AMfA) contact lenses.
- Conditions
- Refractive Errors, Ametropia, Astigmatism
- Trial name
- NCT04908488
- Testing
- Verofilcon A toric contact lenses, Etafilcon A toric contact lenses
- Where
- 8 sites in United States
- Volunteers
- 115 people
- Sponsor
- Alcon Research
Cataract, Astigmatism
Evaluation of the Accuracy & Safety of the LaserArcs Nomogram
Evaluation of the Accuracy and Safety of the LaserArcs Femtosecond Cataract Surgery Arcuate Incision Nomogram in Patients Undergoing Cataract Surgery and Astigmatism Reduction
- Trial name
- NCT05278442
- Testing
- LaserArc
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Research Insight LLC
Astigmatism
Non-dispensing Study to Check Prescription Equivalence of Two Daily Disposable Toric Contact Lens Types
The purpose of this study is to determine whether the prescription determined for a new daily disposable toric contact lens will be a good match to a prescription determined for an existing brand of lens.
- Trial name
- NCT01120782
- Testing
- etafilcon A toric contact lens with new wetting agent, etafilcon A toric contact lens
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Clinical Performance of Existing Wearers of Enfilcon A Following a Refit With Fanfilcon A Lenses for 4 Weeks
The aim of this dispensing study is to evaluate the clinical performance of habitual wearers of enfilcon A lenses following a refit with fanfilcon A lenses over 4 weeks of daily wear.
- Trial name
- NCT02670473
- Testing
- fanfilcon A (test)
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataract
Efficacy of Lutein, Zeaxanthine and Trypan Blue to Stain the Anterior Lens Capsule
Effectiveness of lutein, zeaxanthin and trypan blue to stain the anterior lens capsule during cataract phacoemulsification.
- Trial name
- NCT01621789
- Testing
- dye of lutein, zeaxanthin, trypan blue
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Federal University of São Paulo
Myopia
Evaluate the Safety and Efficacy of Two Types of Circular Column Modulated Lenses for Delaying the Progression of Myopia
Clinical trial to evaluate the safety and effectiveness of two kinds of ring band cylindrical lens in delaying the progression of myopia
- Trial name
- NCT05288335
- Testing
- Circular cylindrical mirror modulated frame glasses (compact), Circular cylindrical mirror modulated frame glasses (strong defocus), single vision frame glasses
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Posterior Capsule Opacification
LEC Proliferation in Vivo and In-vitro
Investigate the proliferative capacity of individual lens epithelium capsule specimens in vitro and correlate it to the risk of developing PCO
- Trial name
- NCT03857685
- Testing
- In-vitro model
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Myopia, Refractive Error
Effect of Contact Lens Wear on Immune Cell Density and Morphology of the Ocular Surface
The purpose of this study is to utilize in-vivo confocal microscopy to describe differences in corneal epithelial immune status across three lens care regimens in new contact lens wearers.
- Trial name
- NCT01250925
- Testing
- ReNu MultiPlus® MultiPurpose Solution, OPTI-FREE® RepleniSH®, Clear Care®
- Where
- 2 sites in United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Intraocular Lens, Cataract
Predicting Intraocular Lens Tilt Using OCT Measurements and Partial Least Squares Regression Modelling
During cataract surgery an artificial intraocular lens (IOL) is implanted in the eye to replace the lens and to correct the refraction for distance vision. Misalignment of IOLs can cause severe loss of visual quality.
- Trial name
- Tilt (NCT06305338)
- Testing
- Optical Coherence Tomography
- Where
- Austria
- Volunteers
- 110 people
- Sponsor
- Johannes Kepler University of Linz
Myopia
Dual-focus Soft Contact Lenses for Controlling Rapid Progressive Myopia in Young Adults
This study aims to evaluate the effectiveness and acceptability of dual-focus soft contact lenses in controlling rapid myopia progression in adults through a randomized controlled trial.
- Trial name
- NCT06528860
- Testing
- MiSight® 1 day soft contact lenses, Proclear® 1 day soft contact lenses
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Refractive Error, Myopia
Clinical Performance of a New Daily Disposable Contact Lens Worn in an Established Contact Lens Wearing Population
This study seeks to evaluate the clinical and subjective performance of a new daily disposable soft contact lens.
- Trial name
- NCT00708643
- Testing
- Habitual Silicone Hydrogel Contact Lens, narafilcon A
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract
Multi-center Ocular Biological Parameters Study
This study is a multi-center study, which collects data from multiple regions to obtain the general biological characteristics of the Chinese population.
- Trial name
- NCT04340635
- Where
- China
- Volunteers
- 20,000 people
- Sponsor
- Aier School of Ophthalmology, Central South University
Bilateral Cataract
Cost-effectiveness of ISBCS vs. DSBCS
The purpose of this study is to evaluate the effectiveness and costs of immediately sequential bilateral cataract surgery (ISBCS) compared to delayed sequential bilateral cataract surgery (DSBCS) in order to determine whether…
- Trial name
- NCT03400124
- Testing
- ISBCS, DSBCS
- Where
- Netherlands
- Volunteers
- 858 people
- Sponsor
- Maastricht University Medical Center
Cornea
Influence of Silicone Hydrogel Extended Contact Lens Wear on Corneal Sensitivity
Soft contact lens wear reduces the amount of oxygen reaching the eye, which may have an influence on corneal sensitivity. The aim of this study is to measure corneal sensitivity with means of liquid jet esthesiometry at baseline…
- Trial name
- NCT05298917
- Testing
- silicone hydrogel contact lens
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Daniela Nosch
Cataract
ReSTOR Natural +3.0D Study In Japan
The objective of this study is to evaluate safety and effectiveness of ACRYSOF Multifocal Single-piece Intraocular Lens (IOL) Model SN6AD1 when implanted to replace the natural lens following cataract removal.
- Trial name
- NCT00758576
- Testing
- ACRYSOF Multifocal Single-piece Intraocular Lens (IOL) Model SN6AD1
- Where
- Japan
- Volunteers
- 64 people
- Sponsor
- Alcon Research
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.