Clinical trials: Lenses
Lens Diseases
Evaluating Presbyopia-Correcting IOLs in Complex Cataract Cases With Anterior Segment Abnormalities
The goal of cataract surgery has evolved from simply restoring sight to providing clear and comfortable full-range vision. Traditionally, monofocal IOLs remain the routine choice for special cases with anterior segment…
- Trial name
- NCT07321756
- Testing
- Unilateral Posterior Chamber Implantation of Presbyopia-Correcting IOL, Unilateral Posterior Chamber Implantation of Monofocal IOL
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cataracts
Clinical Research of Femtosecond Laser-Assisted Cataract Surgery
Since femtosecond laser was approved for cataract surgery by FDA in 2010, femtosecond laser assisted cataract surgery (FLACS) has demonstrated high precision of capsulotomy, reduced phacoemulsification power and time, and…
- Trial name
- FLACS (NCT02492659)
- Testing
- femtosecond laser-assisted cataract surgery, conventional phacoemulsification
- Where
- China
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Astigmatism
Clinical Performance of Toric Hydrogel Contact Lenses Following One Week of Daily Wear
The aim of this prospective study is to evaluate the clinical performance of filcon IV1 toric and ocufilcon D toric contact lenses after 1 week of wear in each pair.
- Trial name
- NCT02847169
- Testing
- filcon IV1 toric lens, ocufilcon D toric lens
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Ametropia
Endothelial Bleb Response With Toric Lenses
Evaluate the short-term corneal response of oxygen deprivation when using toric contact lenses. The response will be noted by endothelial bleb formation in both open eye and closed eye state.
- Trial name
- NCT00630305
- Testing
- alphafilcon A toric, lotrafilcon B toric, senofilcon A toric
- Where
- Australia
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cystoid Macular Edema
Effect of Nepafenac on Post-operative Macular Swelling Following Uncomplicated Cataract Surgery
Purpose: Study the effect of nepafenac ophthalmic suspension 0.1% to prevent post-operative cystoid macular edema following uncomplicated cataract surgery Participants: Patients having cataract surgery at UNC who meet eligibility…
- Trial name
- NCT00494494
- Testing
- Standard Care, nepafenac
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of North Carolina, Chapel Hill
Myopia
Early Intervention for High Risk Premyopic Children
The purpose of this research project is to add evidence of pharmacological (0.025% atropine) and optical (Defocus Integrated Multiple Segments Triple Enhanced Design spectacle lenses ) approaches for myopia prevention among…
- Trial name
- NCT07863713
- Testing
- 0.025% atropine eye drops, DIMS TED
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University Hospital
Cataract
Evaluation of Quality of Vision and Visual Outcomes With Bilateral Implantation of the Clareon PanOptix Intraocular Lens
To evaluate visual outcomes and quality of vision following bilateral implantation of the Clareon PanOptix intraocular lens (IOL) targeted for emmetropia.
- Trial name
- NCT05518539
- Testing
- The Clareon™ PanOptix™ Trifocal (toric and non-toric models)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Newsom Eye & Laser Center
Intraocular Pressure, Cataracts Senile
Intraocular Pressure Variation by Pneumatic Tonometer Before and After Phacoemulsification
The objective of this study is to evaluate the IOP variation before and 30 days after performing phacoemulsification through pneumatic tonometry, in addition to evaluating the factors possibly related to this variation.
- Trial name
- IPOFACO (NCT03016507)
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- VER Excelência em Oftalmologia
Refractive Error
Clinical Comparison of 4 Daily Disposable Soft Contact Lenses
The purpose of this study is to obtain on-eye performance data to inform contact lens product development and to further evaluate product performance in the intended population.
- Trial name
- NCT03349632
- Testing
- verofilcon A contact lenses, senofilcon A contact lenses, stenfilcon A contact lenses
- Where
- 3 sites in United States
- Volunteers
- 68 people
- Sponsor
- Alcon Research
Cataract, Myopia
Evaluating the Effect of Laser Vision Surgery, Phakic Intraocular Lens Implantation, Cataract Surgery, and Pupil Dilation on the Iris Recognition Scanner Function of Smartphone
This study included patients who visit for refractive surgery (photorefractive keratectomy, photorefractive keratectomy with with corneal collagen cross linking, laser in situ keratomileusis, small incision lenticule extraction)…
- Conditions
- Cataract, Myopia, Myopic Astigmatism
- Trial name
- NCT02939001
- Testing
- iris recognition scanner
- Where
- South Korea
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Cataract
Outcomes of Bilateral Implantation of an Enhanced Monofocal Intraocular Lens
To evaluate and compare the visual outcomes of an enhanced monofocal intraocular lens (IOL) with two different monofocal IOLs in patients scheduled for bilateral cataract surgery.
- Trial name
- RCT_ICB00 (NCT06118944)
- Testing
- ICB00 IOL, ZCB00 IOL, CNA0T0 IOL
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- University of Trieste
Cataract
Intraocular Lens Power Calculation Using Pre- and Intra-operative Measurements
Recently a prototype of a combination of an anterior segment OCT (VISANTE; Carl Zeiss Meditec AG) and an operating microscope (OPMI 200; Carl Zeiss Meditec AG) was introduced that allows measurements of the crystalline lens as…
- Trial name
- NCT02513134
- Where
- Austria
- Volunteers
- 75 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Cataract
Neopterin Dosage in the Eye
The purpose of the study is to determine whether neopterin can be dosed in the fluid of the eye's anterior chamber for patient with non-inflammatory and non-infectious ophthalmic pathology.
- Trial name
- CHA (NCT03497481)
- Testing
- Samples
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Cataract, Artificial Intelligence
Validation of the Utility of Rare Disease Intelligence Platform
The prevention and treatment of diseases via artificial intelligence represents an ultimate goal in computational medicine. The artificial intelligence for systematic clinical application has not yet been successfully validated.
- Trial name
- NCT02748044
- Testing
- CC-Cruiser
- Where
- 4 sites in China
- Volunteers
- 53 people
- Sponsor
- Sun Yat-sen University
Myopia, Hyperopia
Multicenter Dispensing Study of Biofinity Lenses in Extended Range
To obtain subjective and objective feedback on the clinical performance of Biofinity lenses after at least two weeks daily wear in existing contact lens wearers compared with their habitual lenses.
- Trial name
- NCT02060539
- Testing
- Biofinity XR
- Where
- 4 sites in United States, Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Astigmatism, Myopia
Performance of Toric Silicone Hydrogel Contact Lenses
The purpose of this study was to evaluate the clinical performance and subjective lens handling (insertion and removal) of two toric silicone hydrogel contact lenses after one month of daily wear each.
- Trial name
- NCT05097144
- Testing
- Lens A (fanfilcon A), Lens B (asmofilcon A)
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- CooperVision, Inc.
Bilateral Cataract, Presbyopia
Symfony/Synergy IOL Combination Outcomes
Current visual outcomes expectations of cataract patients are similar to those of refractive surgery patients. Their desire is to be spectacle independent for far, intermediate and near vision activities.
- Trial name
- NCT05604781
- Testing
- Symfony & Synergy IOL combination
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Center For Sight
Cataract, Glaucoma, Open-Angle
Phaco-UCP Versus Phaco Alone for OAG and Cataract
This study was carried out to evaluate the safety and efficacy of combined phacoemulsification and Ultrasound ciliary plasty (Phaco-UCP) as a first-line surgical treatment of coexisting cataract and op /en angle glaucoma compared…
- Trial name
- NCT04430647
- Testing
- combined phacoemulsification and ultrasound ciliary plasty (Phaco-UCP), Phacoemulsification alone
- Where
- Egypt
- Volunteers
- 61 people
- Sponsor
- Ameera Gamal Abdelhameed
Cataract
Modified Surgical Techniques for Pediatric Cataract Treatment
Pediatric cataract is totally different from adult cataract. There is traditionally no difference in technique between pediatric and adult cataract surgery.
- Trial name
- NCT01844258
- Testing
- Modified technique, Traditional technique
- Where
- China
- Volunteers
- 37 people
- Sponsor
- Sun Yat-sen University
Myopia, Astigmatism
Use of a Disk of Amniotic Membrane (Visio-AMTRIX) in Postoperative Care After PKR
The purpose of this open controlled multicenter trial is to assess the impact of use of an amniotic membrane on post PKR recovery.
- Conditions
- Myopia, Astigmatism, Hypermetropia
- Trial name
- NCT05247658
- Testing
- Therapeutic lens alone, Therapeutic lens + amniotic membrane (Visio-AMTRIX)
- Where
- 3 sites in France
- Volunteers
- 9 people
- Sponsor
- TBF Genie Tissulaire
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