Clinical trials: Lenses
Cataract
Comparison of Two Non- Diffractive Extended Depth of Focus Intraocular Lenses
Intra-individual comparison of the PureSee EDOF IOL with the Acunex Vario EDOF IOL set for emmetropia.
- Trial name
- NCT06607848
- Testing
- Low-Add EDOF IOL, EDOF IOL
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Cataract
The Cutting Efficiency of Hybrid Tips in Different Grades of Cataract
The objective is to assess the efficiency (as measured by phaco time, aspiration time, and fluid use) of the hybrid tip in removing cataract grade 3 \& 4 in high and low intraocular pressure (IOP) settings.
- Trial name
- NCT05495555
- Testing
- INTREPID® Hybrid tip
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Cataract and Laser Institute of Southern Oregon
Cataract; Surgery; Phacoemulsification; Biometry; Intraocular Lens Power
Comparison of SRK-T With Kane Formula for Prediction of Refractive Outcome After Phacoemulsification
Cataract is a leading cause of blindness in the world. Cataract surgery is one of the most commonly performed ocular procedures.
- Trial name
- NCT05564455
- Testing
- Biometry with Kane formula, Biometry with SRK-T formula
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Hyperalgesia, Cataract Bilateral Nos
Gabapentin Pretreatment for Staged Bilateral Cataract Operations
To evaluate the effect of oral gabapentin premedication on hyperalgesia in elderly patients undergoing staged bilateral cataract operations under monitored anesthesia care
- Trial name
- NCT03826615
- Testing
- Gabapentin
- Where
- South Korea
- Volunteers
- 64 people
- Sponsor
- Seoul National University Hospital
Dry Eye
A Clinical Evaluation Pilot Study of the Efficacy of Blink® Tears Lubricant Eye Drops for the Relief of Dry Eye Symptoms Following Implantation of Tecnis® Multifocal Introcular Lens
To evaluate the safety and efficacy of BLINK™ tears compared with NO topical artificial tear use in improving subject's visual performance and reduce ocular symptoms of discomfort in subjects who have undergone cataract surgery…
- Trial name
- NCT01061268
- Testing
- No topical artificial tear, Blink® Tears Lubricant Eye Drops
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Innovative Medical
Cataract
Safety and Efficacy of Iontophoretic Dexamethasone Phosphate Delivery Prior to Implantation of a Posterior Chamber IOL
The purpose of this study is to evaluate the safety and efficacy of ocular iontophoresis with dexamethasone phosphate ophthalmic solution EGP-437 using the EyeGate® II Drug Delivery System (EGDS) compared to placebo in patients…
- Trial name
- NCT01602068
- Testing
- Dexamethasone Phosphate Ophthalmic, 100 mM Sodium Citrate Buffer
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Cataract, Lens Opacities
PMCF Retrospective Study Outcomes of a Monofocal Toric Intraocular Lens
This is a monocentric retrospective, open-label clinical study in patients after unilateral or bilateral implantation of hydrophobic acrylic monofocal toric intraocular lens PODEYE TORIC and executed only with standard of care…
- Conditions
- Cataract, Lens Opacities, Astigmatism
- Trial name
- NCT05055076
- Testing
- PODEYE TORIC
- Where
- France
- Volunteers
- 105 people
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
A Study Assessing the Safety and Efficacy of Dextenza® for the Treatment of Ocular Pain and Inflammation Following Surgery for Pediatric Cataract
To assess the safety of Dextenza compared to an active control, prednisolone acetate suspension, for the treatment of postoperative pain and inflammation following ocular surgery for pediatric cataract.
- Trial name
- NCT04539548
- Testing
- Dextenza Ophthalmic Insert, Prednisolone acetate ophthalmic suspension USP 1%
- Where
- 14 sites in United States
- Volunteers
- 65 people
- Sponsor
- Ocular Therapeutix, Inc.
Presbyopia
Clinical Evaluation of Two Multifocal Contact Lenses
The aim of this study is to evaluate the patient subjective experiences of the monthly multifocal lens when compared to the daily disposable multifocal lens after 15 minutes of daily wear.
- Trial name
- NCT05457608
- Testing
- Lens A, Lens B
- Where
- Mexico
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Cataract, Presbyopia Correction
Night Driving After Trifocal Versus Monofocal IOL Implantation
This prospective observational cohort study will compare night-driving visual difficulty and visual disturbances after bilateral implantation of an Alcon trifocal intraocular lens or an Alcon monofocal intraocular lens in adults…
- Trial name
- TriIOL (NCT07755189)
- Testing
- AcrySof IQ PanOptix TFNT00 Trifocal Intraocular Lens, Alcon Monofocal Intraocular Lens
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Jin Yang
Myopia
Vistakon Investigational Contact Lenses Worn for Daily Wear
This study compares the performance of an investigational contact lens to a currently marketed lens.
- Trial name
- NCT00717249
- Testing
- galyifilcon A control lens, galyfilcon A with a silver additive
- Where
- 20 sites in United States
- Volunteers
- 529 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Vision Disorders
Pilot Clinical Evaluation of Approved Contact Lenses
This is a pilot evaluation to assess the feasibility of using novel imaging process to characterize lens edge and limbal epithelial thickness profile; lens movement with gaze and blink; and conjunctival microvasculature including…
- Trial name
- NCT02540122
- Testing
- Marketed Contact Lens 1, Marketed Contact Lens 2, Marketed Contact Lens 3
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract, Music Therapy
Anxiety in Cataract Patients Using Preoperative Music Therapy
The researchers designed this study to investigate whether implementing preoperative music intervention in cataract surgery can reduce perioperative anxiety, alleviate postoperative pain, and enhance patient satisfaction with the…
- Trial name
- NCT07296731
- Testing
- Music intervention, No music intervention
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Guangzhou First People's Hospital
Myopia
Controlling Myopia Progression With Soft Contact Lenses
This study is to investigate whether novel soft contact lens optical designs can slow myopia progression.
- Trial name
- NCT00762970
- Testing
- Test Lens 1, Test Lens 2, Control Lens
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Aphakia
Evaluation of the Tecnis™ Multifocal and Crystalens™ Accommodating Intraocular Lenses
The purpose of this study is to compare the visual outcomes with bilateral implantation of Tecnis MF and Crystalens™ AO Aberration-free Accommodating intraocular lens (IOLs) 6 months after post cataract surgery.
- Trial name
- NCT01061281
- Testing
- Tecnis MF IOL, Crystalens AO IOL
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Innovative Medical
Open Angle Glaucoma, Cataract
Safety of Hyaluronan Thiomer i.o. Implant During Combined Phacoemulsification - Non Penetrating Deep Sclerectomy
The study is designed to assess the safety of Hyaluronan Thiomer i.o. implant in patients with primary open angle glaucoma undergoing a combined phacoemulsification - non penetrating deep sclerectomy procedure.
- Trial name
- NCT01887873
- Testing
- Hyaluronan Thiomer i.o. implant
- Where
- Austria
- Volunteers
- 16 people
- Sponsor
- Croma-Pharma GmbH
Contact Lens Related Dry Eye Syndrome
Efficacy Study of a New Eyedrop on Silicone Hydrogel Contact Lens Wearers With Dry Eye Complaints
The objectives of the investigation will be to assess the effect of the repeated usage of a new eye drop on the tear film characteristics of silicone hydrogel contact lens wearers with contact lens related comfort problems and to…
- Trial name
- NCT01543061
- Testing
- OPTIVEtm Plus, No treatment, Blink Contacts® Eye Drops
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- Optometric Technology Group Ltd
Myopia, Progressive
Crossover RCT of TAMER Lenses in Myopia Control
This study is a prospective, randomized, crossover clinical trial with a planned proposed enrollment of 120 Chinese male and female subjects aged 6-12 years without systemic or ocular diseases to follow up their cycloplegic…
- Trial name
- NCT06329986
- Testing
- TAMER Lens Spectacle, SV lenses
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Visual Acuity, Contact Lens Comfort
Assessment of Comfort & Ocular Surface Parameters w Novel Designs of Daily Disposable Silicone Hydrogel Contact Lenses
A comparison of two lens designs manufactured in the same material. The hypothesis is the subjectively rated performance of comfort, vision and lens handling will be better with the modified design compared to the initial design
- Trial name
- BASS (NCT03454542)
- Testing
- Menicon Modified Lens Design
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Refractive Errors, Myopia
Pilot Clinical Performance of a Silicone Hydrogel Lens for Up to Six Nights of Extended Wear
The purpose of this clinical study is to evaluate the on-eye performance of an investigational soft contact lens compared to a commercially available soft contact lens when worn continuously for up to 1 week.
- Conditions
- Refractive Errors, Myopia, Hyperopia
- Trial name
- NCT04403542
- Testing
- Lehfilcon A contact lens, Comfilcon A contact lens
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Alcon Research
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