Clinical trials: Lenses
Cataracts
Clinical Investigation of Visual Function After Bilateral Implantation of Two Presbyopia-Correcting Trifocal Intraocular Lenses (IOL)
The purpose of this study is to clinically evaluate the visual performance of two commercially available presbyopia-correcting Trifocal IOLs.
- Trial name
- NCT02691741
- Testing
- AcrySof® IQ PanOptix™ Presbyopia-Correcting IOL, AT LISA® tri IOL
- Volunteers
- 215 people
- Sponsor
- Alcon Research
Myopia
A Study to Evaluate the Safety and Efficacy of Eye Secret UV Aspheric Silicone Soft (Hydrophilic) 1Day Color Contact Lens
This was a prospective, randomized, open label, parallel, active-controlled clinical study to assess the safety and efficacy of Silicone Color Contact Lens for vision correction.
- Trial name
- NCT06527586
- Testing
- soft contact lens
- Where
- 3 sites in Taiwan
- Volunteers
- 131 people
- Sponsor
- Yung Sheng Optical Co., Ltd.
Myopia
Dispensing Overnight Study in Lenses
The purpose of the study is to evaluate the fit and performance of an investigational soft contact lens in comparison with a currently marketed lens.
- Trial name
- NCT00349856
- Testing
- Biofinity
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Dry Eye Syndromes
Clinical Trial to Evaluate the Symptoms in Symptomatic Contact Lens Wearers Following Application of Intranasal Tear Neurostimulator Versus Control
This study will evaluate the increase in comfort and comfortable contact lens (CL) wear time associated with application of TrueTear (active intranasal neurostimulation) compared with application of TrueTear sham control…
- Trial name
- NCT03325673
- Testing
- TrueTear
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Allergan
Astigmatism
Revive Toric RWE Study
This is a post-market observational clinical investigation. The objective of this observational study is to evaluate the visual performance and HCP satisfaction of REVIVE samfilcon B custom toric contact lenses.
- Trial name
- NCT06785194
- Testing
- REVIVE samfilcon B custom toric contact lenses
- Where
- 3 sites in United States
- Sponsor
- Bausch & Lomb Incorporated
Spinal Cord Injuries
Photovoice for Spinal Cord Injury to Prevent Falls
Falls is a health crisis that costs health care systems billions of dollars each year. This crisis is especially relevant for people living with spinal cord injury (SCI) as most of these people will fall at least once per year.
- Trial name
- NCT04864262
- Testing
- Photovoice
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- University Health Network, Toronto
Pseudoexfoliation Syndrome, Cataract
Influence of Cataract Surgery on Corneal Biomechanical Properties in Patients With Pseudoexfoliation Syndrome
Pseudoexfoliation syndrome is associated with alterations in the biomechanical properties of the cornea. This prospective observational cohort study aims to evaluate changes in corneal biomechanical properties after standard…
- Trial name
- NCT07719101
- Where
- Croatia
- Volunteers
- 70 people
- Sponsor
- Kata Culina
Cataract, Vitrectomy
IRIS Hook Assisted Phacoemulsification in Vitrectomized Eyes
Although phacoemulsification in previously vitrectomized eyes is a relatively safe procedure comparing with extracapsular cataract surgery, it is still more challenging than in eyes without previous vitrectomy because of the…
- Trial name
- NCT03584139
- Testing
- IRIS HOOK, TRADITION
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Presbyopia, Cataract
Feasibility Study of Laser Treatment of the Crystalline Lens to Correct Presbyopia
The study will evaluate whether the LensAR laser system can be used in the lens of the eye to increase the ability to read and/or see near objects
- Trial name
- NCT01062412
- Testing
- LensAR Laser System
- Where
- Philippines
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- LensAR Incorporated
Cataract
Intraocular Lens Calculation Using Artificial Intelligence
The aim of this study is to investigate the lens diameter (LD) as a useful parameter in intraocular lens (IOL) power calculation by using several different non-invasive imaging techniques.
- Trial name
- NCT07202767
- Testing
- Swept-Source Anterior Segment OCT
- Where
- Austria
- Volunteers
- 170 people
- Sponsor
- Johannes Kepler University of Linz
Myopic Progression
Monthly Replacement Orthokeratology for Myopia Control in Existing Lens Wearers
The two-year prospective study aims at investigating the benefits of frequent replacement (monthly) orthokeratology lenses in myopia control in terms of effectiveness in control and prevention of ocular complications.
- Trial name
- MR1 (NCT04295707)
- Testing
- orthokeratology, Menicon Progent A+B
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Cataract, Multifocal Intraocular Lens
Visual Outcomes in Patients Contralaterally Implanted With PanOptix Pro and Clareon Vivity Compared to Bilateral Implantation of PanOptix Pro
Title: Visual Outcomes in Patients Contralaterally Implanted with PanOptix Pro and Clareon Vivity Compared to Bilateral Implantation of PanOptix Pro Sponsor: Brian Shafer, MD, Shafer Vision Institute Objective: To compare visual…
- Trial name
- NCT07076277
- Testing
- Clareon PanOptix Pro and Clareon Vivity Intraocular Lens, Clareon PanOptix Pro Intraocular Lenses
- Where
- 5 sites in United States
- Volunteers
- 346 people
- Sponsor
- Brian Shafer
Cataract
Penetrance of Third Generation Fluoroquinolones in Eyes With Functioning Filtering Blebs
Based on previous results with eyes without filtering blebs, the aqueous concentrations of ofloxacin and levofloxacin will exceed the concentration of ciprofloxacin after either topical or topical plus oral administration.
- Trial name
- NCT00392275
- Testing
- Ofloxacin 0.3%, Ciprofloxacin 0.3%, Levofloxacin 0.5%
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- Indiana University
Unilateral Cataract Extraction, Congenital Cataract
A Randomized Study in Children Ages Birth Through Three Years Undergoing Unilateral Cataract Extraction With or Without Lens Replacement
The purpose of this study is to evaluate the effect of OMS302 compared to phenylephrine when administered in irrigation solution during cataract extraction on intraoperative pupil diameter, acute postoperative pain, and safety in…
- Trial name
- ILR7 (NCT02132312)
- Testing
- OMS302, Phenylephrine HCl
- Where
- 11 sites in United States
- Volunteers
- 78 people
- Sponsor
- Omeros Corporation
Cataract
Effect of the Color of the Intra-eye Implant in the Cataract Surgery on the Sleep
The cataract surgery (550 000 operations per year in France) is to replace the cloudy lens with a refractive implant. Two colors of implants are available: white implants, filtering out ultraviolet and yellow implants, filtering…
- Trial name
- IOL et sommeil (NCT02304900)
- Testing
- white implant, yellow implant
- Where
- 3 sites in France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Tours
Angle Closure Glaucoma, Glaucoma
Anterior Segment Changes by Optical Coherence Tomography (OCT) in Phaco- Trabeculectomy
1. Develop a measurement protocol by OCT imaging and characterization of the anterior chamber change in glaucoma patients before and after surgery. 2. Show the effect of combined surgery in control of intra ocular pressure.
- Conditions
- Angle Closure Glaucoma, Glaucoma, Cataract Secondary
- Trial name
- NCT03626675
- Testing
- phaco- trabeculectomy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Cataract
VisiOn Restoration With FluidVisION Accommodating Intraocular Lens (AIOL)
The objective of this study is to obtain an initial assessment of the safety and performance of an investigational AIOL in patients undergoing cataract extraction and IOL implantation.
- Trial name
- ORION (NCT03925545)
- Testing
- FluidVision AIOL, AcrySof IQ monofocal IOL, Cataract surgery
- Volunteers
- 85 people
- Sponsor
- PowerVision
Cataract
Data Collection After Intensity IOL Implantations
Hanita Lenses new Intensity IOL and Intensity Toric were been designed to have very high efficiency of light leading to a high MTF, wide focal ranges of far, intermediate and near vision and minimal loss of light energy.
- Trial name
- NCT06220331
- Testing
- Intra Ocular Lens
- Where
- Argentina
- Volunteers
- 31 people
- Sponsor
- Hanita Lenses
Cataract
Comparison of Stellaris Standard Infusion With Stellaris Elite
Clinical performance of phacoemulsification platform Stellaris Elite with standard irrigation fluid bottles in myopic eyes. Anterior chamber depth and patients comfort will be compared between the two groups.
- Trial name
- NCT03751254
- Testing
- Stellaris Elite
- Where
- Austria
- Volunteers
- 35 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Cataract Surgery, Intraocular Lens
Reliability and Effectiveness of New Enova Preloaded Intaocular Lens and Cartridge System
Evaluation of the safety and efficacy of the new Enova® preloaded monofocal intraocular lens and cartridge injector system in cataract surgery
- Trial name
- NCT07288086
- Testing
- Preloaded intraocular lens system
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Istanbul University
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