Clinical trials: Lenses
Cataract
PureSee/Odyssey Mix-and-Match IOL
Observational, prospective, bilateral, single-arm investigator-initiated study. Single cohort at one site: TECNIS PureSee intraocular lens in the dominant eye and TECNIS Odyssey intraocular lens in the non-dominant eye.
- Trial name
- NCT07898917
- Testing
- Mix-and-match PureSee/Odyssey cohort
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Gainesville Eye Associates
Myopia, Astigmatism
Subjective Comfort With Multipurpose Care Solutions in Soft Contact Lens Wearers
The purpose of this study was to assess the comfort of OPTI-FREE RepleniSH in soft contact lens wearers.
- Conditions
- Myopia, Astigmatism, Refractive Error
- Trial name
- NCT01211535
- Testing
- OPTI-FREE RepleniSH multipurpose solution, ReNu Biotrue multipurpose solution, Silicone hydrogel contact lenses
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Alcon Research
Dry Eye
OC-01 (Varenicline) Nasal Spray and Dry Eye Signs and Symptoms in Daily Disposable Contact Lens Wearers
This study is a single center, prospective, randomized, controlled, double-masked, two-arm investigator-initiated study to investigate the efficacy of OC-01 (varenicline) nasal spray on the signs and symptoms of dry eye disease…
- Trial name
- NCT05161208
- Testing
- OC-01 (varenicline 0.6mg/ml) Nasal Spray
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Center for Ophthalmic and Vision Research, LLC
Cataracts
Manual Small Incision Cataract Surgery Outcomes in an Educational Setting
The overall objective is to determine the visual outcomes and cost to perform Manual Small Incision Cataract Surgery (MSICS) in a small cohort at an academic medical center in the United States.
- Trial name
- MSICS (NCT02277314)
- Testing
- Manual Small Incision Cataract Surgery
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Arizona
Cataract
Visual Outcomes of Tecnis Symfony Opti-Blue EDOF Intraocular Lens (IOL)
Tecnis Symfony Optiblue EDOF IOL is the latest version of Tecnis Symfony IOL with a violet light filter (VLF), which blocks short-wavelength light and improves the quality of vision while minimizing visual disturbances.
- Trial name
- NCT06500416
- Testing
- Tecnis Symfony OptiBlue/ Tecnis Symfony OptiBlue toric IOL
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Coastal Eye Surgeons PLLC
Cataract
Clinical Evaluation of Modified 2.2mm Microincision Phacoemulsification for Age-related Cataract
This study is a single-center, parallel-group, randomized controlled trial with the following objectives: to compare the incidence of post-operative descemet membrane detachment (DMD) in phacoemulsification surgery between…
- Trial name
- NCT04014699
- Testing
- modified 2.2mm microincision, conventional 2.2mm microincision
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia
Correction of Myopia Evaluation Trial 2
The purpose of the study is to determine if progressive addition lenses (PALs) versus single vision lenses (SVLs) slow the progression of low myopia in children with poor accommodative responses (i.e., large accommodative lags)…
- Trial name
- COMET2 (NCT00320593)
- Testing
- Progressive Addition Lenses (PALs), Single Vision Lenses (SVLs)
- Where
- 8 sites in United States
- Volunteers
- 118 people
- Sponsor
- Jaeb Center for Health Research
Myopia
Evaluation of the Feasibility a New Silicone Hydrogel Contact Lens
The objective of this study is to determine the clinical feasibility and to evaluate the product performance of an investigational contact lens.
- Trial name
- NCT01309906
- Testing
- Investigational lens, Air Optix Aqua lens
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Astigmatism
Multicenter Dispensing Study of Biofinity Toric Made-To-Order Lenses in Extended Power Ranges
The study hypothesis is that the Biofinity Toric XR lenses will perform as well as or better than the participants' habitual contact lenses.
- Trial name
- NCT02193178
- Testing
- comfilcon A Toric
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- CooperVision, Inc.
Myopia
The Immediate Effect of Defocus Spectacles On the Choroid Thickness Using Optical Coherence Tomography on Children
The purpose is to examine temporary changes in the subfoveal choroid thickness after removal and after resumed use of Defocus Incorporated Multiple Segment Spectacle Lenses (DIMS).
- Trial name
- TIDOCT (NCT06234189)
- Testing
- Defocus Incorporated Multiple Segment Spectacle Lenses (DIMS)
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Vejle Hospital
Cataracts
Cataract Surgery in Indian Patients With or Without LenSx® Laser
The purpose of this study is to record and analyze the profile and outcome of cataract patients receiving phacoemulsification (phaco) and artificial intraocular lens (IOL) implantation with or without femtosecond laser-assisted…
- Trial name
- NCT02605408
- Testing
- LenSx® laser system, Phacoemulsification
- Sponsor
- Alcon Research
Ametropia
Performance of Aspheric Hydrogel Lenses After a Refit With Sphere Silicone Hydrogel Lenses for 4 Weeks
The aim of this prospective study is to evaluate the clinical performance of habitual wearers of methafilcon A aspheric lenses after a refit with fanfilcon A sphere lenses for 4 weeks of daily wear.
- Trial name
- NCT03835078
- Testing
- methafilcon A contact lenses, fanfilcon A contact lenses
- Where
- Mexico
- Volunteers
- 42 people
- Sponsor
- CooperVision, Inc.
Cataract, Signs and Symptoms
Spherical Aberration and Contrast Sensitivity in IOLs
Purpose: To determine whether implantation of an intraocular lens (IOL) with a modified anterior aspheric surface results in reduced spherical aberration and improved contrast sensitivity after cataract surgery.
- Conditions
- Cataract, Signs and Symptoms, Pseudophakia, Lens Diseases
- Trial name
- IOLs (NCT00576485)
- Testing
- Cataract surgery and intraocular lens implantation
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Myopia, Hyperopia
Multipurpose Disinfecting Solution Compatibility With a Silicone Hydrogel Contact Lens
The purpose of this study is to verify the compatibility of a silicone hydrogel lens when used with four multipurpose disinfecting solutions (OPTI-FREE® RepleniSH®, ReNu MultiPlus®, Solo-Care Aqua™ and MeniCareTM Soft).
- Trial name
- Amethyst (NCT00520689)
- Testing
- Silicone Hydrogel Contact Lens
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Lens Implantation, Intraocular
Incidence of Glaucoma-related Adverse Events in Pediatric Secondary Intraocular Lens Implantation
To compare the incidence of glaucoma-related adverse events of in-the-bag versus ciliary-sulcus-fixed secondary intraocular lens (IOL) implantation in pediatric aphakia
- Trial name
- NCT05136950
- Testing
- Secondary in-the-bag IOL fixation, Secondary ciliary sulcus IOL fixation
- Where
- China
- Volunteers
- 228 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia, Hyperopia
A Clinical Comparison of Two Soft Contact Lenses
The study objective was to gather short-term clinical performance data for two soft contact lenses.
- Trial name
- NCT05741450
- Testing
- Lens 1 (monthly replacement), Lens 2 (daily disposable)
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- CooperVision, Inc.
Cataract
Evaluation Of Bilateral Tecnis Multifocal Versus ReSTOR 3D Intraocular Lenses
The purpose of this study is to compare the visual outcomes with bilateral implantation of Tecnis MF and ReSTOR intraocular lenses (IOLs) 6 months post cataract surgery.
- Trial name
- NCT01061918
- Testing
- Tecnis MF, ReSTOR
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Innovative Medical
Grass Pollen Ocular Allergy
The Role of Daily Disposable Contact Lenses in Ocular Allergy
Patients with seasonal allergic conjunctivitis are normally advised to avoid contact lens wear when they are having symptoms. However, modern soft contact lenses which are disposed of daily offer the potential to protect and…
- Trial name
- NCT01125540
- Testing
- Acuvue (Standard Daily Disposable Contact Lens), CIBA Dailies Aquacomfort Plus (Contact Lens - enhance lubricating)
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Aston University
Ophthalmology, Photorefractive Keratectomy ("PRK")
Ocular Bandage Gel (OBG) Pivotal Trial in Patients Undergoing Photorefractive Keratectomy ("PRK")
Prospective, randomized, masked (reading center), controlled pivotal study of Ocular Bandage Gel (OBG) vs. a bandage contact lens (BCL) in subjects who have undergone bilateral photorefractive keratectomy (PRK).
- Conditions
- Ophthalmology, Photorefractive Keratectomy ("PRK"), Laser Assisted Surgery, Refractive Surgery
- Trial name
- NCT03938883
- Testing
- Ocular Bandage Gel (OBG), Bandage Contact Lens (BCL)
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Presbyopia
Comparison of Two Multifocal Contact Lenses
The purpose of this study is to compare two multifocal contact lenses in presbyopic wearers.
- Trial name
- NCT01250054
- Testing
- Lotrafilcon B contact lens, Comfilcon A contact lens
- Volunteers
- 17 people
- Sponsor
- CIBA VISION
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