Clinical trials: Lenses
Dry Eye, Visual Acuity
Treating Lid Wiper Epitheliopathy
Lid wiper epitheliopathy (LWE) is a relatively new entry into the abundance of clinical ocular surface health signs. LWE was first reported in 2002 as a potential cause for dry eye disease (DED) (Korb et al., 2002).
- Trial name
- TLWE (NCT06671041)
- Testing
- Preservative Free eye drop
- Where
- 4 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Primary Open Angle Glaucoma, Pseudoexfoliative Glaucoma
Phacotrabeculotomy Versus CCI+Phaco in Patients With Borderline Control of Intraocular Pressure
The purpose of the study is to determine whether combined cataract and glaucoma surgery (phacotrabeculotomy)is more effective in lowering intraocular pressure than cataract surgery alone in patients with borderline control of…
- Trial name
- NCT00346931
- Testing
- Phacoemulsification, implantation of intraocular lens, Phacoemulsification, Implantation of IOL, trabeculotomy
- Volunteers
- 9 people
- Sponsor
- Medical University of Vienna
Cataract, High Myopia
To Evaluate IOL Position, Clinical Outcome of PanOptix in High Myopic Cataract Patients
To evaluate IOL position, clinical outcome of PanOptix in high myopic cataract patients
- Trial name
- NCT05042856
- Testing
- PanOptix IOL implantation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Wenzhou Medical University
Aphakic Eye
Iris Suture Fixation vs Iris Claw for Correction of Aphakia
Evaluate and compare the advantages and disadvantages of iris suture fixation versus iris claw of posterior chamber IOLs
- Trial name
- IOLs (NCT06933654)
- Testing
- IOL implantation surgery for aphkic eye
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Benha University
Cataract, Shallow Anterior Chamber
Assessment Of Anterior Chamber Configuration Changes After Phacoemulsification
To investigate changes in anterior chamber angle configuration after phacoemulsification and intraocular lens (IOL) implantation with Swept-Source Optical Coherence Tomography (SS-OCT).
- Conditions
- Cataract, Shallow Anterior Chamber, Narrow Angle
- Trial name
- AOACCCAP (NCT02238002)
- Testing
- cataract surgery
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Zheng Qian
Myopia
Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression.
This is a mono-centre, prospective, one-arm, unmask clinical trial to evaluate the effectiveness of test lens in slowing myopia progression with respect to axial length elongation compared to a single vision spectacle lens from…
- Trial name
- NCT05534022
- Testing
- Test myopia control lenses (BSL)
- Where
- Singapore
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia
A Contralateral Dispensing Clinical Trial of Study Test Sapphire Lens Against Enfilcon A Silicone Hydrogel Lens
This was be a randomized, contralateral, double-masked, dispensing study comparing the Study test lens against the control lens over one month of lens wear. The study results were not used for design validation of test lens.
- Trial name
- NCT02518490
- Testing
- Sapphire Lens, enfilcon A
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- CooperVision, Inc.
Healthy Young Adults, Accommodation Disorder
Study in Young Adults to Understand How Glasses With a Small Reading Addition Affect Focusing and Eye Coordination During Vision Tasks
This clinical study aims to understand how glasses with a small reading addition affect the way the eyes focus and work together in young adults with normal near vision.
- Trial name
- BIPBIP (NCT07859917)
- Testing
- Eye exam, Questionnaires, Washout lenses
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Essilor International
Cataracts
Endothelial Cell Loss After Cataract Surgery
The purpose of this study is to compare two cataract surgical technique variations for removing the nucleus of the lens (central part of the lens) in terms of damage to the inner layer of the cornea which is called the…
- Trial name
- NCT00932191
- Testing
- Standard phacoemulsification, Reduced ultrasound phacoemulsification
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of California, San Francisco
Cataract, Dexamethasone
Dexamethasone Versus Metoclopramide for Prophylaxis of Nausea and Vomiting After Cataract Surgery
Postoperative nausea and vomiting (PONV) is a common consequence of ambulatory surgery, affecting up to 80% of high-risk patients and 20-30% overall.
- Trial name
- NCT07086118
- Testing
- 0.9% normal saline, Metoclopramide 10mg, Dexamethasone
- Where
- Egypt
- Volunteers
- 210 people
- Sponsor
- Alexandria University
Recruitment of Participants
Study of the Correlation Between Preoperative Precise Biometrics, Spatial Assessment and Postoperative Visual Quality in Cataract Patients
This study summarizes the experience of precision treatment and postoperative management of various types of cataract, and intend to further improve the quality of Clinical Cataract diagnosis and treatment.
- Trial name
- NCT04833491
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Intraocular Lens
Comparison of the Visual Performance After Implantation of Multifocal Lens
This is a prospective, consecutive, nonrandomized,comparative study. Comparison of the Visual Performance After Implantation of a Trifocal Intraocular Lens and Two Bifocal Intraocular Lenses
- Trial name
- NCT03586271
- Testing
- trifocal lens, bifocal lens 1, bifocal lens 2
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Aier School of Ophthalmology, Central South University
Pupillary Disorders
Correlation of Pupillary Diameter Changewith Age and Anterior Chamber Depth After Cataract Surgery
PURPOSE: To assess the correlation between the change in pupil diameter, age and depth of the anterior chamber after 3 months of cataract surgery both in photopic and mesopic conditions.
- Trial name
- NCT04286646
- Where
- Spain
- Volunteers
- 55 people
- Sponsor
- Clinica Oftalmologica TACIR
Marfan Syndrome, Ectopia Lentis
Classifying Ectopia Lentis in Marfan Syndrome Into Five Grades of Increasing Severity
Marfan syndrome is characterized by musculoskeletal manifestations, cardiovascular disease and ocular abnormalities, particularly ectopia lentis.
- Trial name
- NCT04319107
- Testing
- ophthalmological examinations using a slit lamp bio microscopy and a three-mirror lens, standard procedure.
- Where
- France
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Myopia
Evaluation of Two Silicone Hydrogel Lenses Over a One Month Period
The purpose of this trial is to compare two different contact lenses during 4 weeks of wear.
- Trial name
- NCT00810511
- Testing
- Lotrafilcon A contact lens, Comfilcon A contact lens
- Volunteers
- 213 people
- Sponsor
- CIBA VISION
Age-related Cataract
IOL-capsular Complex After Different Intraocular Lenses Implantation in Patients With High Myopia
The IOL-capsular complex is formed after cataract surgery and intraocular lens (IOL) implantation. Early postoperative mechanical wrapping of the anterior and posterior capsules plays a significant role in preventing IOL…
- Trial name
- NCT05255796
- Testing
- one-piece, plate-haptic
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Wenzhou Medical University
Healthy
Mapping the Impact of Gut Microbiota on Brain and Behavior Through the Lens of GABA
Gut microbiota produce different metabolites within the human body, which include neurotransmitters. Animal studies have demonstrated a critical role for the gut microbiota in various aspects of brain and behavioural function…
- Trial name
- GutBrainGABA (NCT05698862)
- Testing
- Probiotic
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Reading
Capsule Opacification, Pseudophakia
Posterior Capsule Opacification and Frequency of Nd:YAG Treatment and of Two Microincision IOLs: Tecnis ZCB00 and Acrysof SA60AT
Age-related cataract is the main cause of impaired vision in the elderly population worldwide. In the UK, more than half of people who are over 65 have some cataract development in one or both eyes.
- Conditions
- Capsule Opacification, Pseudophakia, Cataract
- Trial name
- NCT01742910
- Testing
- intraocular lens implantation
- Where
- Austria
- Volunteers
- 54 people
- Sponsor
- Medical University of Vienna
Retinitis Pigmentosa, Cataract
The Role of Capsular Tension Ring (CTR) in Anterior Capsular Contraction
This is a Randomized Controlled Trial to study the role of Capsular Tension Ring in patients with Retinitis Pigmentosa
- Trial name
- ACO (NCT00717080)
- Testing
- IOL surgery
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Aurolab
Intraocular Lens Rotation, Capsular Tension Ring
Rotational Stability of a Hydrophobic Acrylic Plate Haptic Intraocular Lens Using a Capsular Tension Ring - An Intraindividual Comparative Study
The present study should investigate the influence of a capsular tension ring on postoperative rotational stability of a plate haptic hydrophilic acrylic intraocular lens.
- Trial name
- ConTRol (NCT04226196)
- Testing
- Implantation of an intraocular lens
- Where
- Austria
- Volunteers
- 65 people
- Sponsor
- Medical University of Vienna
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