Clinical trials: Lenses
Presbyopia
Visual and Economic Profits of ReSTOR® Multifocal Intraocular Lenses (IOL) on Public Health Patients in Spain
Surgical correction of presbyopia is possible via the implantation of multifocal intraocular lenses after removal of the crystalline lens.
- Trial name
- NCT01088282
- Testing
- Cataract surgery
- Where
- 2 sites in Spain
- Volunteers
- 120 people
- Sponsor
- University of Barcelona
Refractive Error
Clinical Comparison of Two Silicone-Hydrogel Contact Lenses
The objective of this study is to evaluate the clinical performance of two silicone-hydrogel contact lenses.
- Trial name
- NCT00762385
- Testing
- galyfilcon A, comfilcon A
- Volunteers
- 97 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataract
Effect of Artificial Tears on Biometry
The purpose of this study is to determine if measurements for cataract surgery are improved with use of additional lubrication with artificial tears.
- Trial name
- NCT04230720
- Testing
- Systane Complete
- Where
- United States
- Sponsor
- Weill Medical College of Cornell University
Myopia
A Study to Evaluate the Safety and Efficacy of DSFNC1 Soft Hydrophilic Contact Lenses and SiHy Color Soft Hydrophilic Contact Lenses
This project is an open, parallel, randomly controlled, and non-inferiority clinical trial of DSFNC1 soft hydrophilic contact lenses with SiHy color soft hydrophilic contact lenses.
- Trial name
- NCT06616480
- Testing
- BenQ Materials DSFNC1 soft hydrophilic contact lenses, Visco SiHy Color soft hydrophilic contact lenses
- Where
- China
- Volunteers
- 192 people
- Sponsor
- BenQ Materials Corporation
Cataracts
Comparison of Tetracaine 0.5% and Lidocaine 2% Jelly for Topical Phacoemulsification Cataract Surgery
The purpose of this study is to determine if there is a difference on the penetration of betadine 5% when using lidocaine 2% jelly versus topical tetracaine 0.5% in topical cataract surgery.
- Trial name
- NCT00827073
- Testing
- tetracaine 0.5%, Lidocaine 2% Jelly
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hermann Eye Center
Ptosis, Blepharoptosis
Bandage Contact Lens in Post Operative Ptosis Patients
This study is being conducted to determine whether the use of bandage contact lens after ptosis surgery provides any benefits for the patient or is unnecessary.
- Trial name
- NCT03375879
- Testing
- Bandage contact lens
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
Cataract and IOL Surgery
HUD Surgical Guidance for Toric Alignment
This study aims to assess the accuracy of toric intraocular lens (IOL) alignment axes as calculated and displayed by a novel digital guidance system.
- Trial name
- CG-Toric (NCT07325188)
- Testing
- Cassini Guidance
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Gainesville Eye Associates
Cataract
Proof-of-concept Study for a New Intraocular Lens, MODEL C0001
This study is a 12-month, prospective, 2-arm (1 test \& 1 control), randomized (1 test:1 control), bilateral, subject/evaluator-masked clinical investigation of the EPV IOL versus the standard TECNIS monofocal control IOL.
- Trial name
- NCT05036070
- Testing
- Model C0001, Model ZCB00
- Where
- 2 sites in France
- Volunteers
- 113 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
VR-based Informed Consent, Cataract and Intraocular Lens Surgery
VR for Cataract Anxiety Lowering Management
Cataract is currently the leading cause of blindness globally, and surgery is the only effective treatment. With the advancement of medical technology, cataract surgery is usually performed under topical anesthesia, which means…
- Trial name
- VR-CALM (NCT07586280)
- Testing
- Virtual reality simulation of intraoperative audiovisual experience
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Vitrectomy, Retinal Detachment
Pars Plana Vitrectomy With 25-gauge 20000 Cpm, Bevel-tip Cutter
Report efficiency and clinical outcomes using 25-gauge, bevel-tip, 20000 cut per minute vitrectomy probe among eyes with various vitreo-retinal diseases
- Conditions
- Vitrectomy, Retinal Detachment, Vitreous Hemorrhage, Macular Holes
- Trial name
- HYPE (NCT04404296)
- Testing
- 25-gauge, bevel-tip, 20000 cut per minute pars plana vitrectomy
- Where
- Philippines
- Volunteers
- 50 people
- Sponsor
- Peregrine Eye and Laser Institute
Contact Lens Comfort
Acuvue Oaysis Contact Lens Wearers Being Refit Into P7 Contact Lenses
Determine the likelihood of successfully refitting a satisfied AOA CL wearers into P7A CLs
- Trial name
- NCT06955403
- Testing
- Precision 7 contact lenses
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Myopia, Refractive Errors
DD T2 Daily Disposable Registration Trial
The purpose of this study is to evaluate the performance of the investigational verofilcon A contact lens compared to the commercially available delefilcon A contact lens, by assessing visual acuity as the primary variable.
- Trial name
- NCT03305770
- Testing
- verofilcon A contact lenses, delefilcon A contact lenses
- Where
- 6 sites in United States
- Volunteers
- 107 people
- Sponsor
- Alcon Research
Dry Eye
Safety and Efficacy of Optive in Contact Lens Wearers With Dry Eyes
The purpose of this study is to determine if Optive®eye drops are safe for people who wear contact lenses and have dry eyes. The second goal of the study is to determine if using Optive®eye drops can improve my dry eye scores on…
- Trial name
- NCT00469573
- Testing
- 1. Optive
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Cataract
A Prospective Observational Case Series of a Four-ring-haptic Acrylic One-piece IOL
To describe biocompatibility, postoperative results and complications after implantation of the Corneal Quatrix Evolutive (Corneal, Croma, Austria) intraocular lens, a hydrophilic acrylic intraocular lens (IOL) with 4-haptic…
- Trial name
- Qu01 (NCT01244373)
- Where
- Austria
- Volunteers
- 9 people
- Sponsor
- General Hospital Linz
Contact Lens Solutions
A Range of Contact Lenses and Care System Combinations
The objective of this study is to compare the short-term clinical response to all combinations of two lens types: fanfilcon A and comfilcon A with two care systems: Hy-Care and Lite.
- Trial name
- NCT03632083
- Testing
- Hy-Care Contact Lens Solution, Lite Contact Lens Solution, fanfilcon A soft contact lens
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- CooperVision, Inc.
Myopia
An Evaluation of the Effectiveness of Dual Focus Soft Contact Lenses in Slowing Mypoia Progression
The purpose of this study is to determine whether a new type of soft contact lens with a unique optical design (dual focus) is effective at slowing the progression of myopia (near-sightedness) in children.
- Trial name
- NCT01729208
- Testing
- Dual Focus Soft Contact Lens, Single Vision Soft Contact Lens
- Where
- 4 sites in Canada, Portugal and 2 more
- Volunteers
- 144 people
- Sponsor
- CooperVision, Inc.
Macular Disease, Rhegmatogenous Retinal Detachment
Combined Vitrectomy and Femtosecond Laser-assisted Cataract Surgery
Based on the progress of cataract surgery, intraocular lens development, vitreoretinal surgery and anesthesia technology in recent years, the purpose of this study is to develop a new type of more accurate and minimally invasive…
- Conditions
- Macular Disease, Rhegmatogenous Retinal Detachment, Epiretinal Membrane, Cataract
- Trial name
- NCT05588037
- Testing
- FLACS +PPV+IOL + air, FLACS +PPV+IOL + epiretinal membrane peeling + Ozurdex, FLACS + PPV+IOL + internal limiting membrane peeling + air
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Aier School of Ophthalmology, Central South University
Cataract
Bioequivalence of Eye Drops and Spray Administration of Vigamox
The study compares the amounts of Vigamox absorbed when administered as eye drops or in a spray form. Both administrations will be prior to patients undergoing elective cataract surgery and the aqueous samples will be analyzed by…
- Trial name
- NCT00666042
- Testing
- Vigamox - administration in spray form, Vigamox eye drops
- Where
- Israel
- Volunteers
- 16 people
- Sponsor
- Advanced Ophthalmic Pharma
Cataract
Comparison of Femto-laser and Manually Created Clear Corneal Incisions During Cataract Surgery
The aim of this study is to test the hypothesis, that in terms of Surgically Induced corneal Astigmatism (SIA), Higher-order Aberrations (HOA), and wound geometry the femtosecond clear corneal incisions (CCIs) created during…
- Trial name
- Z8_CCI (NCT04082273)
- Testing
- Femtosecond Laser for Cataract Surgery, Conventional Cataract Surgery
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- Ziemer Ophthalmic Systems AG
Astigmatism
Performance of Fanfilcon A Toric Lenses After at Least One Month Wearing Enfilcon A Toric Lenses
This is a prospective, multi-center, subject-masked, bilateral, daily wear, two-month dispensing study
- Trial name
- NCT02921412
- Testing
- fanfilcon A
- Where
- 4 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
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