Clinical trials: Leptospirosis, open to volunteers
Leishmaniasis, Leptospirosis
Serological Measurement of Montpellier Professionals' Contacts with Infectious Agents Responsible for Animal-borne Diseases
Zoonoses and arboviroses refer to a group of diseases transmitted from animals to humans, either directly or indirectly (via mosquitoes, ticks or contact with contaminated environments).
- Conditions
- Leishmaniasis, Leptospirosis, Brucellosis, Q Fever
- Trial name
- SEZAM (NCT06859619)
- Testing
- Peripheral venous blood sample
- Where
- France
- Volunteers
- 183 people
- Sponsor
- University Hospital, Montpellier
Mild Leptospirosis
Comparing Two Antibiotic Therapy Periods (3 Versus 7 Days) in Patients With Mild Leptospirosis and Seen at the Hospital in 5 French Overseas Departments (Martinique, Guadeloupe, French Guiana, Reunion, Mayotte)
Leptospirosis is a globally distributed neglected tropical disease affecting subtropical and tropical areas, such as the Caribbean and the Indian Ocean, with favorable climatic conditions for disease transmission.
- Trial name
- LEPTO3 (NCT04211649)
- Testing
- 3 days of antibiotherapy
- Where
- 5 sites in French Guiana, Guadeloupe and 3 more
- Volunteers
- 220 people
- Sponsor
- University Hospital Center of Martinique
Q Fever, Leptospirosis
Assessment of the Risk of Zoonotic Infections in Prisons in French Guiana
The prison system in French Guiana is characterized by severe overcrowding, high levels of promiscuity, poor sanitary conditions, and the documented presence of potential reservoirs or vectors of zoonotic diseases, particularly…
- Conditions
- Q Fever, Leptospirosis, Chagas Disease, Histoplasmosis
- Trial name
- CARYANA (NCT07808775)
- Where
- French Guiana
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cayenne
Leptospirosis
Leptospirosis Care Bundle Study
So in management of Leptospirosis patients There really is no another approach to treatment. The importance of the problem was acknowledged by the researchers.
- Trial name
- NCT05425524
- Testing
- Care Bundle
- Where
- Thailand
- Volunteers
- 300 people
- Sponsor
- Chulalongkorn University
Leptospirosis
Leptospirosis Registry - LeptoScope
Leptospirosis is a worldwide zoonotic diseases caused by pathogenic Leptospira spp. Human are accidental hosts, who acquired infections after exposition to animal urine, contaminated water or soil, infected tissue.
- Trial name
- Leptoscope (NCT04288674)
- Testing
- Retrospective data collection of demographics, Retrospective data collection of underlying diseases, Retrospective data collection of duration of hospitalization
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Cologne
Leptospirosis, Chemoprophylaxis
These Studies That Evaluated the Efficacy of Antibiotics for Leptospirosis Treatment.
The goal of this randomized controlled trial is to study antibiotic chemoprophylaxis to prevent leptospirosis of high-risk populations.
- Trial name
- NCT07865156
- Testing
- Doxycycline
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Leptospirosis
Characterizing the Host Response to Leptospirosis for Better Diagnosis and Prognosis - NIHFI
Leptospirosis is a zoonosis found worldwide, but particularly in humid subtropical and tropical zones. It is caused by pathogenic bacteria of the Leptospira species of the spirochete family.
- Trial name
- NIHFI (NCT06945822)
- Testing
- Blood sample, Urine Sample
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Leptospirosis
Preventive Strategies for Early and Late Complications of Leptospirosis
The goal of this clinical trial is to learn if complement factor I (CFI) works to predict development of complications in participants with leptospirosis.
- Trial name
- NCT07127718
- Testing
- Prophylactic Plasma Transfusion, Hemoperfusion, Extracorporeal Membrane Oxygenation
- Where
- 3 sites in Philippines
- Volunteers
- 678 people
- Sponsor
- National Kidney and Transplant Institute, Philippines
Malaria Fever, Zika
Xpert® Tropical Fever Test on GeneXpert® Edge X System
This is a multi-site, observational, cross-sectional clinical study that includes geographically diverse sites within and outside the United States.
- Conditions
- Malaria Fever, Zika, Dengue Fever, Leptospirosis
- Trial name
- NCT07520279
- Testing
- Xpert Tropical Fever test
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- Cepheid
Dengue, Chikungunya
Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective
RACSMEI addresses the high burden of infectious diseases in low- and middle-income countries, including Cambodia, where limited surveillance and laboratory capacity often obscure etiologies and transmission dynamics.
- Conditions
- Dengue, Chikungunya, Zika Virus Infection, Japanese Encephalitis
- Trial name
- RACSMEI (NCT07358910)
- Where
- Cambodia
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur du Cambodge
Leptospirosis, Jarisch Herxheimer Reaction
Ex Vivo Study of Leukocyte Responses in the Blood of Patients With Leptospirosis and ex Vivo Testing of a New Host-targeted Therapeutic Strategy to Restore Phagocytosis of Leptospira
Leptospirosis is a neglected zoonosis caused by pathogenic spirochetes of the genus *Leptospira*, occurring mainly in humid tropical and subtropical regions.
- Trial name
- NEUTROLEPTO-NC (NCT07611591)
- Testing
- 24 ml blood sample at H0, 16 ml blood sample at H3
- Volunteers
- 70 people
- Sponsor
- Institut Pasteur