Clinical trials: Lesion
Anterior Cruciate Ligament Injuries, Meniscus Lesion
The Effect Of Addıtıonal Surgery On Muscle Strength, Proprıoceptıon And Balance In Anterıor Crucıate Lıgament Surgery
Meniscal tears and RAMP lesions are frequently seen together with ACL injuries. The aim of this study was to evaluate the effects of meniscus repair and RAMP lesion repair ACL reconstruction surgery in terms of muscle strength…
- Trial name
- NCT06319040
- Testing
- Muscle strength measurement, Knee joint proprioception, Balance
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medipol University
Atrial Fibrillation New Onset
Diagnostic Validation of Wearable ECG Monitoring Patch, ATP-C120
A new wearable patch-type device, ATP-C120 (ATsens, Seongnam, Korea) is a novel, single-lead ECG monitoring device and can continuously monitor the ECG signal for upto 11 days.
- Trial name
- NCT04857268
- Testing
- wearable continuous ECG monitoring patch, ATP-C120
- Where
- 2 sites in South Korea
- Volunteers
- 320 people
- Sponsor
- Seoul National University Bundang Hospital
Ischemic-type Biliary Lesions
Mesenchymal Stem Cells Transplantation for Ischemic-type Biliary Lesions
Ischemic-type biliary lesions (ITBLs) are a major cause of graft loss and mortality after orthotopic liver transplantation (OLT). For now, there are still lacking effective treatment for ITBLs.
- Trial name
- NCT02223897
- Testing
- huc-MSCs
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Yang Yang
Postdural Puncture Headache
Pregabalin in Treatment of Postdural Puncture Headache
Lumbar puncture (LP), often known as a "spinal tap," is a standard medical technique pioneered in the late 1900s by Heinrich Quincke.
- Trial name
- NCT06271486
- Testing
- Pregabalin 75mg, An epidural blood patch (EBP), conservative treatment.
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Al-Azhar University
Bone Lesion
Interventional Radiology in Bony Lesions
To explore the capability of the interventional radiology techniques in management of the painful bony lesions .
- Trial name
- NCT05738941
- Testing
- radiofrequency ablation, angioembolization
- Volunteers
- 50 people
- Sponsor
- Assiut University
Locally Advanced Non Small Cell Lung Cancer, Metastatic Non Small Cell Lung Cancer
Local Ablative Stereotactic Radiotherapy for Residual Hypermetabolic Lesion in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer Long-term Responders to Immunotherapy
At present, it is recommended to continue immunotherapy until progression or unacceptable toxicity. However, only a minority of patients benefits from a durable response and most see the disease progress despite several months of…
- Trial name
- TRAILOCLORI01 (NCT05111197)
- Testing
- SRT, Immunotherapy
- Where
- 5 sites in France
- Volunteers
- 112 people
- Sponsor
- Institut Cancerologie de l'Ouest
Sweat Analysis
Sweat Patch Validation
To determine the validity of a prototype patch in measuring sweating rate and sweat electrolyte concentration during moderate intensity exercise against well-established reference methods in a controlled laboratory and in field…
- Trial name
- NCT04240951
- Testing
- Sweat patch
- Where
- 2 sites in United States
- Volunteers
- 552 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Duodenal Diseases, White Spot Lesion
İmportance of Scattered White Spots Detected in the Duodenum and Their Relationship wıth Zonulin
With our study, we aimed to determine whether there is a correlation between zonulin, which plays a crucial role in intestinal barrier function and is implicated in the etiopathogenesis of many chronic and autoimmune diseases…
- Trial name
- NCT06200129
- Testing
- sws grade 1, sws grade 2, control
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Uterine Cervical Cancer, High Grade Squamous Intraepithelial Lesions
A Multicenter Real-world Study of Screening of Cervical Cancer Based on Photoelectric Detection
The main purpose of this study is to explore the accuracy and clinical value of fluorescent photoelectric cervical lesion image detector as a screening and shunt tool for cervical lesions through a multi-center, large-sample…
- Conditions
- Uterine Cervical Cancer, High Grade Squamous Intraepithelial Lesions, Low Grade Squamous Intraepithelial Lesions
- Trial name
- NCT06481930
- Testing
- Detection of Cervical Lesions by Fluorescence Photoelectric Image
- Where
- China
- Volunteers
- 20,000 people
- Sponsor
- Lei Li
Pancreatic Cancer
Evaluating the Number of Passes Required for Diagnostic Cell Block During EUS-FNA of Solid Pancreatic Mass Lesions
This study will test the amount of tissue, called "cell block", obtained from your pancreas. Patients who are asked to participate in this study have a growth (mass) in the pancreas that needs a biopsy so a diagnosis can be made.
- Trial name
- NCT01809028
- Testing
- EUS FNA with 2 passes, EUS FNA with 4 passes
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- AdventHealth
Hematochezia
Capsule Endoscopy for Severe Hematochezia
Patients with severe hematochezia (bright red blood per rectum) may have a bleeding source proximal to the colon. Visualization of the entire gastrointestinal tract using a second-generation colon capsule endoscopy system could…
- Trial name
- NCT03616041
- Testing
- Second-generation colon capsule endoscopy system
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- CURE Digestive Diseases Research Center
Healthy
Multiple Dose Trial Comparing the Plasma Levels of Two Different Analgesic Transdermal Patch Formulations
The purpose of this study is to determine whether Transtec(R) PRO 70 µg/h and a new buprenorphine patch formulation lead to same plasma levels of buprenorphine after multiple dose application.
- Trial name
- NCT00387777
- Testing
- Patch with centrally acting analgesic, Transtec(R) PRO (buprenorphine)
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Grünenthal GmbH
Coronary Artery Disease With Myocardial Infarction
Pragmatic Trial Comparing Symptom-Oriented Versus Routine Stress Testing in High-Risk Patients Undergoing Percutaneous Coronary Intervention
The primary objective of the POST-PCI trial is to compare the clinical outcomes of a post-percutaneous coronary intervention(PCI) aggressive management strategy of routine noninvasive functional testing to a usual-care strategy…
- Trial name
- POST PCI (NCT03217877)
- Testing
- routine stress testing, No Routine stress testing
- Where
- 11 sites in South Korea
- Volunteers
- 1,700 people
- Sponsor
- Seung-Jung Park
Human Immunodeficiency Virus, Human Papillomavirus-Related Anal Squamous Cell Carcinoma
Anal High-risk HPV, HSIL, and Microbiome Among Hispanic Peoples Living With HIV (PLWH)
The study evaluates if there is relationship between the kinds of bacteria living in the anus (also known as the anal microbiome) and the risk of human papillomavirus (HPV) infection or HPV-related pre-cancer (high-grade squamous…
- Conditions
- Human Immunodeficiency Virus, Human Papillomavirus-Related Anal Squamous Cell Carcinoma, High-Grade Squamous Intraepithelial Lesions
- Trial name
- ULACNet-104 (NCT06651957)
- Testing
- Biospecimen Collection, Questionnaires
- Where
- 3 sites in United States, Mexico and 1 more
- Volunteers
- 217 people
- Sponsor
- University of California, San Francisco
Hemorrhage, Pelvic Fracture
Pre-hospital Advanced Therapies for Control of Hemorrhage - Pelvis
The purpose of this study is to determine whether the use of pelvic binders in the ambulance setting improves outcomes including mortality in patients with pelvic fractures.
- Trial name
- PATCH (NCT02855060)
- Testing
- Pelvic Binder
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Wake Forest University Health Sciences
Alzheimer's Disease
Compliance and Tolerability of Rivastigmine Transdermal Patch 10 cm² in Patients With Probable Alzheimer's Disease.
This study will evaluate compliance, tolerability, safety, efficacy and caregiver burden of rivastigmine patch 10 cm² treatment in people with Alzheimer's disease (MMSE 10-26) initiating therapy for the first time with a…
- Trial name
- CARE (NCT00731224)
- Testing
- Rivastigmine transdermal patch
- Where
- 40 sites in Australia, Malaysia and 3 more
- Volunteers
- 380 people
- Sponsor
- Novartis Pharmaceuticals
Peripheral Nerve Injuries, Sensory Deficit
The Effect of Pre-operative Electrical Stimulation on Peripheral Nerve Regeneration.
Traumatic injury to the peripheral nerves is most common in the young population with high associated costs to the patient, as well as to society. These range from acute healthcare cost to loss of productivity and rehabilitation.
- Conditions
- Peripheral Nerve Injuries, Sensory Deficit, Digital Nerve Lesion
- Trial name
- NCT03205124
- Testing
- Electrical Stimulation
- Where
- 2 sites in Canada
- Volunteers
- 38 people
- Sponsor
- University of Alberta
Pancreatic Neoplasm
22G FNA Needle vs. 22G ProCore Needle
The aim of this research study is to identify the best needle for performing biopsy during EUS procedures. There are two types of needles for performing biopsy: A FNA needle that provides a small sample of tissue for analysis and…
- Trial name
- NCT01394159
- Testing
- 22G ProCore biopsy needle, 22G standard FNA needle
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- AdventHealth
Vitiligo
Transplantation of Basal Cell Layer Suspension Using Derma-rolling System in Vitiligo
Actually the methods for melanocyte delivery are invasive and often sophisticated. The dermarolling system with needles causing tiny microinjuries in the epidermis could offer a minimally invasive and painless method of…
- Trial name
- NCT02962180
- Testing
- Dermabrasion with dermaroller
- Where
- Morocco
- Volunteers
- 10 people
- Sponsor
- Mohammed V Souissi University
Educational Problems, Melanoma (Skin)
Passive Versus Active Educational Interventions for Melanoma Recognition
This study evaluates the efficacy of a passive versus an active educational intervention in increasing the ability of laypersons at low risk for melanoma development, in recognizing atypical skin melanocytic lesions.
- Trial name
- PAMela (NCT04507048)
- Testing
- Active educational intervention, Passive educational intervention
- Where
- 7 sites in Italy
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
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