Clinical trials: Lesion
Head Lice
Dermal Safety Study to Evaluate Potential Irritation of Abametapir Lotion
The purpose of the study is to determine the irritation potential of repeat applications of abametapir lotion on normal skin.
- Trial name
- NCT02061813
- Testing
- Abametapir Lotion 0.74% w/w, Sodium Lauryl Sulfate, Saline 0.9%
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Central Nervous System (CNS) Lesions, Brain Metastases
Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent
This Phase 2 clinical trial will study RVP-001, a new manganese-based MRI contrast agent, in people who are known to have gadolinium-enhancing central nervous system (CNS) lesions, for example brain tumors or multiple sclerosis.
- Conditions
- Central Nervous System (CNS) Lesions, Brain Metastases, Brain Neoplasms, Brain Neoplasms, Benign
- Trial name
- NCT06322342
- Testing
- RVP-001
- Where
- 5 sites in United States
- Volunteers
- 18 people
- Sponsor
- Reveal Pharmaceuticals Inc.
Dental Caries in Children
SDF Effectiveness on Arresting Caries in Children
Purpose: To assess the clinical effectiveness of silver diamine fluoride (SDF) to control asymptomatic cavitated carious lesions compared to conventional glass ionomer restoration in preschool children.
- Trial name
- NCT05872542
- Testing
- Silver Diamine Fluoride (SDF), Glass Ionomer Restoration (GI), Sodium fluoride varnish with nano-sliver particles (NaF-AgNP)
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Umm Al-Qura University
Universal Adhesive
Clinical Performance of Self-cured Universal Adhesive for Restoring Cervical Lesions in Geriatric Patients
the study is conducted to evaluate the clinical performance of PALFIQUE universal adhesive (Tokuyama self-cure universal adhesive), Versus 3m ESPE™ single bond Universal Adhesive, for restoring cervical lesions in geriatric…
- Trial name
- NCT05054673
- Testing
- universal adhesive
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain
Pharmacokinetic Study of Synera™ in Neonates and Infants
This study will measure the amount of lidocaine and tetracaine in the blood after a 30 minute application of Synera.
- Trial name
- NCT00747669
- Testing
- lidocaine 70mg and tetracaine 70mg topical patch
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- ZARS Pharma Inc.
Skin Irritation
Patch Test Skin Irritation/Sensitization of Cetaphil Daily Facial Moisturizer SPF 50
Determine if Cetaphil Daily Facial Moisturizer SPF 50 proves to be a contact sensitizer or irritant in certain individuals.
- Trial name
- NCT01887860
- Testing
- Cetaphil Daily Facial Moisturizer SPF 50
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Femoral Acetabular Impingement
Arthroscopic Treatment for Femoral Acetabular Impingement Syndrome With Gluteus Medius Lesions.
To evaluate the prognosis of femoral acetabular impingement syndrome (FAIS) patients with gluteus medius lesions after hip arthroscopy.
- Trial name
- NCT04951180
- Testing
- Demographic data and MRI images extraction
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking University Third Hospital
Shoulder Instability
Circumferential Lesions of the Glenoid Labrum
Objective: Symptomatic pan-labral or circumferential (360 degree) tears of the glenohumeral labrum are an uncommon injury. The purpose of this study is to report the prospective surgical results of circumferential lesions of the…
- Trial name
- NCT00849927
- Where
- 2 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Society of Military Orthopedic Surgeons
Carious Lesion, Cervical Caries
Clinical Performance of ARS Containing Universal Adhesives in Carious Cervical Lesions
Evaluation of composite restorations done in carious cervical lesions restored by a conventional universal adhesive in comparison to a universal adhesive that contains and resistant silane coupling agent according to the Modified…
- Trial name
- NCT06572124
- Testing
- universal adhesive without Acid resistant silane coupling agent, universal adhesive with Acid resistant silane coupling agent
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bariatric Surgery
New Imaging Tools to Explore Impact of Bariatric Surgery on Pancreatic Lesions: PACHIBA- Bariatric Surg
The investigators propose an exploratory study aiming at assessing the impact of surgical bariatric treatment on the improvement of pancreatic lesions detected by MRI.
- Trial name
- PACHIBA (NCT04746703)
- Testing
- Magnetic Resonance Imaging
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Heart Disease
A Prospective Evaluation in a Randomized Trial of TAXUS in the Treatment of De Novo Coronary Artey Lesions
This study is to compare the safety and performance of two stents coated with the same drug (the TAXUS Element Paclitaxel-Eluting Coronary Stent System and the TAXUS Express2 Paclitaxel-Eluting Coronary Stent System).
- Trial name
- NCT00693979
- Testing
- TAXUS Element Stent or TAXUS Express Stent
- Sponsor
- National University Hospital, Singapore
Coronary Artery Disease
A Study of the Presillion Stent in de Novo Coronary Lesions
The PRESILLION Study is a non-randomized, multi-center, single-arm study evaluating the safety of an approved Cobalt Chromium bare metal stent system for the treatment of ischemic heart disease attributable to a stenotic de novo…
- Trial name
- PRESILLION (NCT00722579)
- Testing
- PRESILLION cobalt chromium stent
- Where
- Belgium
- Volunteers
- 101 people
- Sponsor
- Cordis US Corp.
Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple
Intravenous Indocyanine Green for Localization of Intra-thoracic Lesions
This is a clinical trial to evaluate the intravenous administration of indocyanine green (ICG) as a method of intra-thoracic lesion localization.
- Trial name
- NCT03097627
- Testing
- ICG Intervention, Near Infrared Camera
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Brigham and Women's Hospital
Colorectal Cancer, Advanced Adenocarcinoma
A Prospective, Multi-center, Observational Study for Signal-C Test Evaluation
To evaluate the performance characteristics of Signal-C™ a plasma circulating free-DNA test, to detect colorectal cancer and advanced precancerous lesions (APL) in an average risk screening population for 45 and over.
- Trial name
- NCT06059963
- Testing
- Signal-C™
- Where
- United States
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Universal Diagnostics
Digital Breast Tomosynthesis
The Added Value of DBT Over Mammography in Local Tumor Staging in Patients With BIRADS 4 or 5 Lesions
Compare the diagnostic accuracy of tomosynthesis with 2D mammography in cases with suspected BI-RADS 4 or 5 to determine its potential benefit for staging
- Trial name
- NCT06854887
- Testing
- digital breast tomosynthesis and mammography
- Volunteers
- 64 people
- Sponsor
- Assiut University
Hemorrhage
The EVARREST® Fibrin Sealant Patch Liver Study
To evaluate the safety and hemostatic effectiveness of EVARREST® Fibrin Sealant Patch (EVARREST) versus standard of care treatment (SoC) in controlling parenchymal bleeding during hepatic surgery.
- Trial name
- NCT01993888
- Testing
- EVARREST® Fibrin Sealant Patch, Standard of Care (SoC)
- Where
- 17 sites in United States, Australia and 2 more
- Volunteers
- 102 people
- Sponsor
- Ethicon, Inc.
Basal Cell Carcinoma of Skin, Squamous Cell Carcinoma
Two-photon Fluorescence Microscopy of Dermatologic Biopsies
The goal of this study is to investigate the ability of two-photon fluorescence microscopy to evaluate dermatologic biopsies. The main questions it aims to answer are: How well do two-photon fluorescence images of biopsies taken…
- Conditions
- Basal Cell Carcinoma of Skin, Squamous Cell Carcinoma, Melanocytic Lesion, Adult
- Trial name
- NCT07773688
- Testing
- Two photon microscopy imaging
- Where
- United States
- Volunteers
- 644 people
- Sponsor
- University of Rochester
Solitary Pulmonary Nodule, Multiple Pulmonary Nodules
Cryobiopsy Versus Forceps Biopsy for Pulmonary Lesions
Purpose: Patients with peripheral lung nodules require evaluation for lung cancer. Our aim is to assess the diagnostic yield of a new technique, transbronchial cryobiopsies, in patients at risk for lung cancer.
- Trial name
- NCT02983903
- Testing
- transbronchial biopsy
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Pennsylvania
Solid Cancer, Metastatic Spinal Lesions
Metastatic Spinal Bone Marrow Response to Radiation Therapy Using T1 Weighted Dynamic Contrast-Enhanced Perfusion
The purpose of this study is to assess imaging methods including Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE-MRI) and perfusion for the cancer that has spread to the spine.
- Trial name
- NCT02376127
- Testing
- Dynamic contrast enhancement MRI
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
To Healthy Volunteer, Virtual Lesions for Aphasia
Effects of Navigated Repetitive Transcranial Magnetic Stimulation According to Post-stroke Aphasia Types
Repetitive transcranial magnetic stimulation induced virtual lesions for aphasia.
- Trial name
- NCT01877161
- Testing
- Repetitive magnetic stimulation to superior temporal gyrus, Repetitive magnetic stimulation to middle temporal gyrus
- Where
- South Korea
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
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