Clinical trials: Lesion
Pulmonary and Mediastinal Lesions
Feasibility of Confocal Laser Microscopy (CLM)in the Computed Tomography-guided Needle Biopsy of Pulmonary and Mediastinal Lesions
The hypothesis of this proposal is that needle confocal laser microscopy (nCLM) may improve the yield of trans thoracic needle biopsy (TTNB) of lung or mediastinal lesions by differentiating between viable and necrotic tissue.
- Trial name
- NCT01979692
- Testing
- confocal laser microscopy CLM at trans thoracic needle biopsy TTNB, CT guided trans thoracic needle biopsy
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Sheba Medical Center
Von Hippel-Lindau Syndrome, Renal Cell Carcinoma
Evaluation of Sunitinib Malate in Patients With Von Hippel-Lindau Syndrome (VHL) Who Have VHL Lesions to Follow
The goal of this clinical research study is to learn if sunitinib malate (SU011248) can help to control VHL. The safety of this drug will also be studied.
- Conditions
- Von Hippel-Lindau Syndrome, Renal Cell Carcinoma, Hemangioblastoma
- Trial name
- NCT00330564
- Testing
- SU011248
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- M.D. Anderson Cancer Center
Alzheimer's Disease
An Open-label Extension to Evaluate the Efficacy and Safety of the Rivastigmine Transdermal Patch in Patients With Probable Alzheimer's Disease
The goal of this research study is to evaluate, in the open-label extension phase, the safety and efficacy of the rivastigmine transdermal patch in patients with probable Alzheimer's Disease
- Trial name
- NCT00219232
- Testing
- Rivastigmine Transdermal Patch
- Volunteers
- 868 people
- Sponsor
- Novartis
Coronary Artery Disease
BIOFLOW-INDIA Safety and Clinical PerFormance of the Drug Eluting ORSIRO Stent in Single de Novo Coronary Artery Lesions
The objective of this clinical investigation is to assess the safety and clinical performance of the Orsiro Limus Eluting Stent System in Indian subjects with single de-novo coronary artery lesions.
- Trial name
- NCT01426139
- Testing
- Percutaneous Coronary Intervention Biotronik Orsiro DES
- Where
- 4 sites in India
- Volunteers
- 120 people
- Sponsor
- Biotronik AG
Ankle Sprain
Proof-of-concept Study of NSAID Hydrogel Patch in Treatment of Acute Pain
The safety and the efficacy of the Esflurbiprofen Hydrogel Patch will be assessed in comparing with placebo in the treatment of acute pain due to ankle sprain
- Trial name
- NCT02729207
- Testing
- Esflurbiprofen Hydrogel Patch
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Teikoku Seiyaku Co., Ltd.
Cesarean Section Complications
Lidocaine Patch Versus Intravenous Lidocaine in Pain Relief After Cesarean Section
To evaluate the efficacy of lidocaine patch applied around wound in reduction of postoperative pain and illus compared to intravenous lidocaine infusion and placebo after cesarean section.
- Trial name
- NCT04505644
- Testing
- lidocaine patch, IV lidocaine
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Aswan University Hospital
Cerebral Palsy, Lower Urinary Tract Symptoms
Incontinence and MRI Results in Children with Cerebral Palsy
More than 50 % of children and adults with cerebral palsy experience lower urinary tract symptoms (LUTS). This can negatively influence quality of life of the child and the total social environment.
- Trial name
- NCT05060211
- Testing
- Vancouver symptom score for dysfunctional elimination syndroms, Magnetic resonance imaging
- Where
- Belgium
- Volunteers
- 125 people
- Sponsor
- University Hospital, Ghent
Adrenal Tumor, Adrenal Incidentaloma
CRISAL Study:Cancer Risk In Secreting Adrenal Lesions
The aim of the present study is to report the cancer risk in secreting adrenal lesions. Secondary aims: to compare the incidence of cancer in secreting versus non-secreting adrenal lesions, in order to evaluate whether adrenal…
- Conditions
- Adrenal Tumor, Adrenal Incidentaloma, Surgery
- Trial name
- CRISAL (NCT06520111)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Roma La Sapienza
Long Head of Biceps Brachii Lesions, Rotator Cuff Tears
Tenotomy Versus no Tenotomy LHB in Rotator Cuff Repair
The function of the long head of the biceps tendon (LHBT) in the glenohumeral joint generates controversy among researchers. For some, the tendon does not have a significant function in the shoulder, while others consider it acts…
- Trial name
- NCT07289334
- Testing
- ROTATOR CUFF REPAIR
- Volunteers
- 60 people
- Sponsor
- Consorci Sanitari de Terrassa
WHYX Lesion, Extremely Well Differentiated Intestinal-type Adenocarcinoma
Clinical Outcomes of Endoscopic Resection for Treating WHYX Lesion
Endoscopically, WHYX cancers demonstrated a vague extent of tumor spread due to pale color changes in both the background atrophic and metaplastic gastric mucosa.
- Trial name
- NCT01451034
- Testing
- WHYX cancer group
- Where
- South Korea
- Volunteers
- 872 people
- Sponsor
- Samsung Medical Center
Pancreatic Neuroendocrine Tumors, Clear Cell Renal Carcinoma
Near Infrared Technology and Laparoscopic Resection of Pancreatic Lesions: the COLPAN Project
The purpose of this study is to determine whether the use of Near-Infrared Technology can guide the laparoscopic resection of hypervascular neoplasms of the pancreas.
- Conditions
- Pancreatic Neuroendocrine Tumors, Clear Cell Renal Carcinoma, Solid Pseudopapillary Tumors of the Pancreas
- Trial name
- NCT02685553
- Testing
- NIR
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Pulp Necrosis, Periapical Lesion
Success Rate of Single Versus Two Visit Regenerative Treatment Protocol in Non Vital Mature Anterior Teeth
This study evaluates success rate of non vital mature anterior teeth with periapical lesion treated by regenerative endodontic protocol in single visit versus two visit technique.
- Conditions
- Pulp Necrosis, Periapical Lesion, Anterior Teeth
- Trial name
- NCT03717337
- Testing
- Single visit pulp regeneration, Two visit pulp regeneration
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy Volunteers
Skin Safety Study to Evaluate the Sensitizing Potential in Healthy Volunteers
This is a single center, randomized, controlled, within subject comparison, multiple dose study to determine the sensitization potential of M518101 on normal skin under occlusive patch condition.
- Trial name
- NCT02256930
- Testing
- M518101, M518101 Vehicle, Sodium lauryl sulfate
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Maruho North America Inc.
Treatment Of Stenotic Lesions In Native Coronary Arteries.
BioFreedom FIM Clinical Trial.
Prospective, multi center, randomized, single blinded study designed to demonstrate the safety and effectiveness of the Biosensors BioFreedom Drug-Eluting Coronary Stent Delivery System at multiple time points compared to the…
- Trial name
- NCT01172119
- Testing
- Biofreedom Drug Eluting Stent, Tuxus Liberte Drug Eluting Stent
- Where
- 4 sites in Germany
- Volunteers
- 182 people
- Sponsor
- Biosensors Europe SA
Leukoplakic Lesions
Comparison Between Two Different High Power Ablative Lasers in the Treatment of Oral Leukoplakia
Oral leukoplakia is a precancerous lesion with relatively high malignant transformation potential. They are often treated by wide surgical excisions or conservative retinoids therapy.
- Trial name
- NCT03233165
- Testing
- Er:YAG laser, Er,Cr:YSGG laser
- Volunteers
- 54 people
- Sponsor
- University of Zagreb
Hamstring Injury, Muscle Rupture
Effect of NMES+ on Hamstring Lesion (3a/3b)
The goal of this clinical trial is to analyze the effect of the electrical stimulation superimposed onto movement in healthy semi-professional athletes who sustained a type 3a/3b hamstring strain injury.
- Conditions
- Hamstring Injury, Muscle Rupture, Hamstring Sprain
- Trial name
- NCT05786300
- Testing
- NMES+, Rehab
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Università degli studi di Roma Foro Italico
Coronary Artery Disease
Study Safety and Performance of the Biomime Stent in Patients With Single, De Novo, Non-Complex Coronary Lesions
1.) Indigenously developed and designed BioMimeTM is a predictably safe \& efficacious 3rd generation drug eluting stent (DES) with a propensity to minimize vascular injury by use of an intelligent mix of ultra-low strut…
- Trial name
- meriT-1 (NCT01507519)
- Testing
- Sirolimus Eluting Coronary Stent System (Biomime)
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Meril Life Sciences Pvt. Ltd.
Iliac Artery Stenosis
EPIC Nitinol Stent System in the Treatment of Atherosclerotic Lesions in Iliac Arteries
The ORION study is being conducted to determine whether the Epic™ Nitinol Stent for primary stenting of iliac atherosclerotic lesions shows acceptable performance at 9 months.
- Trial name
- ORION (NCT00896337)
- Testing
- Epic™ Nitinol Stent System, Anti-platelet therapy, Anti-coagulation therapy
- Where
- 28 sites in United States
- Volunteers
- 125 people
- Sponsor
- Boston Scientific Corporation
Sentinel Lymph Node
Bronchial NIR Image-guided Resection
This is a clinical trial to evaluate the use of peritumoral injection of near-infrared dye indocyanine green to identify lung lesions and sentinel lymph nodes.
- Trial name
- NCT03097575
- Testing
- ICG Intervention, Near Infrared Imaging
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Lung Non-Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Lung
Robotic Bronchoscopy With Cone CT and Indocyanine Green to Aid Removal of Lung Lesions in Patients With Stage I Non-small Cell Lung Cancer or Lung Metastases, REPLACING Study
This phase II trial studies the use of Ion robotic bronchoscope with a mobile computed tomography (CT) scanner to biopsy tumors and inject a fluorescent dye called indocyanine green to mark the tumor during surgery in patients…
- Conditions
- Lung Non-Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Lung, Stage I Lung Cancer AJCC v8
- Trial name
- NCT04987281
- Testing
- Computed Tomography, Indocyanine Green Solution, Therapeutic Bronchoscopy
- Where
- United States
- Sponsor
- M.D. Anderson Cancer Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.