Clinical trials: Lesion
Genital Tumor, Pigmented Lesions
Comparison of Dermatoscopy X400 Interpreted by 6 Non-dermatologists and an Artificial Intelligence Software Skin Artificial Intelligence Versus Dermatoscopy x 20
Pigmented lesions of the genital mucosa are common, affecting between 10% and 20% of the population. The clinical appearance is sometimes confusing.
- Trial name
- NCT06079619
- Testing
- Analysis of photos of pigmented tumours by the three groups
- Where
- France
- Volunteers
- 157 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Eyes Dry Chronic, Chronic Conjunctivitis of Both Eyes
CDL Validation Study
Ocular surface photography is significantly limited in standardization and reproducibility. This reduces its applicability for clinical monitoring of acute or chronic disease.
- Conditions
- Eyes Dry Chronic, Chronic Conjunctivitis of Both Eyes, Limbal Stem-cell Deficiency, Eye Lesion
- Trial name
- NCT05461469
- Where
- Austria
- Volunteers
- 104 people
- Sponsor
- Occyo GmbH
White Spot Lesion
Evaluation of Two Varnishes on the Improvement of White Spot Lesions in Children
A randomized control trial evaluating the effect of the Giomer varnish versus fluoride varnish on the color improvement of the white spot lesion in permanent anterior teeth of children aged between 8-14 years by using a…
- Trial name
- NCT05775250
- Testing
- giomer varnish
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Other Instability, Shoulder, Hill-Sachs Lesion
Arthroscopic Bankart Repair With and Without Remplissage in Anterior Shoulder Instability
The purpose of this prospective, randomized, controlled trial is to compare subjective patient-reported outcomes and objective clinical results between arthroscopic Bankart repair with and without arthroscopic infraspinatus…
- Trial name
- NCT01324531
- Testing
- Bankart repair and remplissage, Bankart repair
- Where
- 2 sites in Canada
- Volunteers
- 150 people
- Sponsor
- Panam Clinic
Coronary Artery Disease, Bifurcation Lesion
Yao Strategy for the Treatment of de Novo Medina 0,1,0 or 0,0,1 Bifurcation Lesion
Percutaneous coronary intervention for coronary bifurcation lesions represents one of the most challenging procedures in interventional cardiology because of lower angiographic success rate and increased risk of procedural…
- Trial name
- NCT06166459
- Testing
- Drug-coated balloon combined with provisional drug-eluting stent implantation
- Volunteers
- 200 people
- Sponsor
- Xuzhou Third People's Hospital
High-Grade Squamous Intraepithelial Lesions
Laser Ablation in the Treatment of High-grade Cervical Lesions
Cervical laser ablation is an effective, minimally invasive treatment with a low incidence of perinatal complications and minimal impact on fertility.
- Trial name
- NCT06333743
- Testing
- laser ablation, LEEP or Conization
- Volunteers
- 308 people
- Sponsor
- Peking Union Medical College Hospital
Plaque, Dental, Dental Plaque Induced Gingivitis
The Effect of Photodynamic Therapy on Plaque in Orthodontic Patients
This randomized controlled trial will be conducted on 40 orthodontic patients at the Department of Orthodontics, University Hospital Centre Zagreb, Croatia. Respondents will be randomly allocated into 4 groups (n=10).
- Conditions
- Plaque, Dental, Dental Plaque Induced Gingivitis, White Spot Lesion
- Trial name
- NCT06331442
- Testing
- Photodynamic therapy, Tricalcium phosphate (TCP) varnish with 5% NaF, Chlorhexidine varnish
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
High-Grade Squamous Intraepithelial Lesions
Association Between Surgical Timing and Route of Total Hysterectomy After LEEP and Perioperative Risk in Patients With Cervical HSIL
This study aimed to analyze perioperative information in patients with high-grade squamous intraepithelial lesion (HSIL) undergoing total hysterectomy (TH), offering insights into optimal surgery timing, selecting the operation…
- Trial name
- NCT06325592
- Testing
- surgical timing and operation path
- Where
- China
- Volunteers
- 826 people
- Sponsor
- Sichuan Cancer Hospital and Research Institute
Trauma, Brain, Mass Lesion
Assess the Clinical Effectiveness in AI Prioritising CT Heads
Non-Contrast Computed Tomography (NCCT) of the head is the most common imaging method used to assess patients attending the Emergency Department (ED) with a wide range of significant neurological presentations including trauma…
- Conditions
- Trauma, Brain, Mass Lesion, Skull Fractures, Hemorrhage, Intracranial
- Trial name
- ACCEPT (NCT06027411)
- Testing
- qER (qER EU 2.0)
- Where
- 4 sites in United Kingdom
- Volunteers
- 16,800 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Acne, Acne Vulgaris
Clinical Workflow Optimization Using Artificial Intelligence for Dermatological Conditions
Artificial intelligence (AI) based on imaging holds tremendous potential to enhance visual diagnostic accuracy in the medical field.
- Conditions
- Acne, Acne Vulgaris, Alopecia, Androgenetic, Pigmented Lesions
- Trial name
- IDEI_2023 (NCT06263413)
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- AI Labs Group S.L
Anterior Cruciate Ligament Injuries, Meniscus Lesion
The Effect Of Addıtıonal Surgery On Muscle Strength, Proprıoceptıon And Balance In Anterıor Crucıate Lıgament Surgery
Meniscal tears and RAMP lesions are frequently seen together with ACL injuries. The aim of this study was to evaluate the effects of meniscus repair and RAMP lesion repair ACL reconstruction surgery in terms of muscle strength…
- Trial name
- NCT06319040
- Testing
- Muscle strength measurement, Knee joint proprioception, Balance
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medipol University
Cervical Dysplasia, Vulvar Dysplasia
OCT-AF Imaging of Pre-cancers of Vulva and Cervix
The multimodal imaging technology, OCT-AFI, will be used to image sites on the cervix, the endocervical canal and vulva. The imaging probe is small enough, it can be inserted into the endocervical canal for imaging.
- Conditions
- Cervical Dysplasia, Vulvar Dysplasia, Precancerous Lesions, Vulvar Cancer
- Trial name
- NCT03285841
- Testing
- OCT-AFI
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- British Columbia Cancer Agency
Squamous Cell Carcinoma in Situ
A Study to Evaluate Safety, Efficacy of Intralesional Injection of STP705 in Patients With isSCC
The purpose of this trial is to evaluate safety, tolerability and efficacy of various doses of STP705 administered as intralesional injection in subjects with cutaneous squamous cell carcinoma (in situ) skin cancer (isSCC).
- Trial name
- NCT04844983
- Testing
- STP705
- Where
- 7 sites in United States
- Volunteers
- 44 people
- Sponsor
- Sirnaomics
Osteochondral Lesion of Talus, Chondral Defect
AMIC vs. MFx in the Ankle
This clinical investigation is a prospective, double blind, single-centre, randomised controlled trial comparing arthroscopic autologous matrix induced chondrogenesis (AMIC®) to microfracture alone in the treatment of…
- Conditions
- Osteochondral Lesion of Talus, Chondral Defect, Microfracture
- Trial name
- AMARTA (NCT05741983)
- Testing
- Microfracture (MFx), Chondro-Gide®
- Where
- United Kingdom
- Sponsor
- Geistlich Pharma AG
Colorectal Sessile Serrated Lesion
Narrow Band Imaging Versus White Light for the Detection and Miss of Sessile Serrated Lesion
Narrow band imaging(NBI) could improve the detection of colorectal lesions, previous investigations demonstrated its potential in detecting not only colorectal adenoma but non-adenomatous polyps, including sessile serrated…
- Trial name
- NCT05684328
- Testing
- WLI Then NBI Withdrawal, NBI Then WLI Withdrawal
- Where
- China
- Volunteers
- 840 people
- Sponsor
- Changhai Hospital
Nonthrombotic Iliac Vein Lesions, Pelvic Congestive Syndrome
Comparative Study Between Isolated Iliac Vein Stenting Versus Concomitant Iliac Vein Stenting With Pelvic Vein Embolization in Patients With Pelvic Venous Insufficiency Secondary to Nonthrombotic Iliac Vein Lesions
The aim of the study is to compare between Isolated Iliac vein stenting vs Concomitant Iliac vein stenting with pelvic vein embolization in patients with Pelvic Venous Insufficiency secondary to Nonthrombotic iliac vein lesions
- Trial name
- NCT06311669
- Testing
- iliac vein stenting, pelvic vein embolization
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Bone Lesion, Cartilage Degeneration
Efficacy of Bioceramic Materials for Bone Defects Repair
The purpose of this study is to demonstrate the effect of bioceramic implants on the repair of human bone defects, and to explore the application of bioceramic materials in bone defects, bone implantation, and bone fusion.
- Conditions
- Bone Lesion, Cartilage Degeneration, Osteo Arthritis Knee, Bone Fracture
- Trial name
- NCT06249906
- Testing
- Commercial bone implant product Group, Mirco-structured Bioceramic Group
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
SLAP Lesion
Biceps Tenodesis Alone Versus Biceps Tenodesis and Labrum Repair in Superior Labrum Anteroposterior (SLAP) Lesion Type IV
Aim of this study is comparing results Biceps Tenodesis Alone Versus Biceps Tenodesis and labrum Repair in Superior Labrum Anteroposterior (SLAP) Lesion Type IV
- Trial name
- NCT06300190
- Testing
- Biceps tenodesis alone, Biceps tenodesis and labrum repair
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Osteoarthritis, Knee, Pain
Using Gait Modification to Treat Knee Osteoarthritis in Saudi Arabia: Possibilities and Acceptability.
A variety of biomechanical gait modification interventions can elevate knee loading and improve knee symptoms in knee osteoarthritis patients.
- Conditions
- Osteoarthritis, Knee, Pain, Biomechanical Lesion
- Trial name
- NCT06306079
- Testing
- Lateral Wedge insole
- Where
- Saudi Arabia
- Volunteers
- 17 people
- Sponsor
- King Khalid University
Coronary Artery Disease, De Novo Stenosis Lesion
Advapro Coronary Stent System in Coronary Artery Diseased Patients.
A Prospective, Multicentre, Pilot Study to Evaluate the Safety and Performance of the AdvaPro Sirolimus Eluting Coronary Stent System in Coronary Artery Stenosis in Indian and European Population.
- Conditions
- Coronary Artery Disease, De Novo Stenosis Lesion, Coronary Stent Implantation
- Trial name
- RESTORE (NCT06300268)
- Testing
- AdvaPro Sirolimus Eluting Coronary Stent System
- Volunteers
- 120 people
- Sponsor
- Advanced MedTech Solutions Pvt. Ltd.