Clinical trials: Lesion of the Lung
Lung Cancer, Stereotactic Body Radiotherapy
Stereotactic Body Radiotherapy for Lung Lesions With Markerless Tracking (MLT) on the VERO® SBRT System
Stereotactic Body Radiotherapy (SBRT) delivers an ablative dose of radiation to tumours, with high precision. This technique offers an alternative to surgery for lung lesions.
- Conditions
- Lung Cancer, Stereotactic Body Radiotherapy, Lung Diseases, Lung Cancer Metastatic
- Trial name
- SBRT_LOV (NCT06722885)
- Testing
- Standard radiotherapy treatment
- Where
- Belgium
- Sponsor
- Universitair Ziekenhuis Brussel
Lung Cancer, Multiple Pulmonary Nodules
Real World Registry for Use of the Ion Endoluminal System
The primary objective of this study is to evaluate the performance of the Ion Endoluminal System with real-world use for pulmonary lesion localization or biopsy.
- Conditions
- Lung Cancer, Multiple Pulmonary Nodules, Lung Neoplasms, Respiratory Tract Neoplasms
- Trial name
- NCT06004440
- Testing
- Ion Endoluminal System
- Where
- 16 sites in United States
- Volunteers
- 1,301 people
- Sponsor
- Intuitive Surgical
Lung Cancer
Cost-effectiveness Evaluation of Robotic Surgery in the Removal of Lung Lesions in the ATS of Milan
The goal of this observational study is to compare cost-effectiveness of robotic surgery with open surgery and video-assisted thoracoscopy surgery (VATS) in adult patients, resident in the ATS of Milan area, operated for lung…
- Trial name
- NCT05674227
- Testing
- Robotic surgery, Video-assisted thoracoscopy, Open surgery
- Volunteers
- 5,400 people
- Sponsor
- Agenzia di Tutela della Salute della Città Metropolitana di Milano
Lung Lesion(s) Requiring Evaluation
Transbronchial Lung Biopsy Guided by ENB
The purpose of this study is to evaluate the performance and safety of electromagnetic navigation bronchoscopy (ENB) system and system kit (iLungTM SuperNavigator) .
- Trial name
- NCT03628222
- Testing
- ENB-TBLB, X-ray-TBLB
- Where
- 8 sites in China
- Volunteers
- 226 people
- Sponsor
- Changzhou LungHealth Medtech Company Limited
Lung Neoplasms, Diagnosis
Benefit of Cone-beam CT and Robotic-Assisted Bronchoscopy During Bronchoscopy
This randomized controlled trial evaluates the integration of cone-beam computed tomography (CBCT) and robotic-assisted bronchoscopy (RAB) for diagnosing pulmonary lesions, hypothesizing improved diagnostic yield compared to…
- Conditions
- Lung Neoplasms, Diagnosis, Lung Cancer
- Trial name
- NCT06489678
- Testing
- Robotic Assisted Bronchoscopy
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- University of Zurich
Solitary Pulmonary Nodule, Coin Lesion, Pulmonary
The Watch the Spot Trial
This study will compare two clinically accepted protocols for surveillance imaging in individuals who are found to have a small pulmonary nodule on chest computed tomography (CT) scans.
- Conditions
- Solitary Pulmonary Nodule, Coin Lesion, Pulmonary, Lung Neoplasms, Carcinoma, Non-small-cell Lung
- Trial name
- WTS (NCT02623712)
- Testing
- More Frequent Surveillance Strategy, Less Frequent Surveillance Strategy
- Where
- United States
- Volunteers
- 34,686 people
- Sponsor
- Kaiser Permanente
Lung Non-Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Lung
Robotic Bronchoscopy With Cone CT and Indocyanine Green to Aid Removal of Lung Lesions in Patients With Stage I Non-small Cell Lung Cancer or Lung Metastases, REPLACING Study
This phase II trial studies the use of Ion robotic bronchoscope with a mobile computed tomography (CT) scanner to biopsy tumors and inject a fluorescent dye called indocyanine green to mark the tumor during surgery in patients…
- Conditions
- Lung Non-Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Lung, Stage I Lung Cancer AJCC v8
- Trial name
- NCT04987281
- Testing
- Computed Tomography, Indocyanine Green Solution, Therapeutic Bronchoscopy
- Where
- United States
- Sponsor
- M.D. Anderson Cancer Center
Peripheral Pulmonary Lesion
Evaluate the Diagnostic Value of BTPNA for PPL: a Real-world Study
The study is designed as a multicenter prospective trial of BTPNA for the diagnosis of peripheral pulmonary lesions in the real world.
- Trial name
- NCT04597346
- Testing
- Bronchoscopic Transparenchymal Nodule Access
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Chest Hospital
Lung Cancer, Pneumothorax
Effectiveness of the Autologous Blood Patch Method in Lung Biopsies
In this retrospective study, investigators aimed to evaluate the effectiveness of the autologous blood patch method in percutaneous transthoracic lung biopsies performed with the coaxial technique.
- Trial name
- NCT05904574
- Testing
- Autologous blood patch, Percutaneous transthoracic biopsy
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Trakya University
Lung Cancer
Transbronchial Catheter Aspiration and Transbronchial Needle Aspiration in the Diagnosis of Lung Cancer
The aim of this study is prospectively to determine the diagnostic sensitivity of Transbronchial Catheter Aspiration (TBCA) in comparison with Transbronchial Needle Aspiration (TBNA) in the diagnosis of peripheral nodules and…
- Trial name
- NCT00807391
- Testing
- TBCA, TBNA
- Where
- 2 sites in Germany
- Volunteers
- 48 people
- Sponsor
- Helios Klinik Ambrock
Lung Neoplasm, Lung Disease
The Value of VOCs Analysis in Exhaled Breath for Pulmonary Benign and Malignant Lesion Diagnosis
The purpose of this study is to analysis the volatile organic gases(VOCs) in exhaled breath of pulmonary lesion patients and healthy controls, in order to find the difference of composition and concentration among groups.
- Trial name
- VOCs (NCT02965300)
- Where
- China
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Lung Cancer, Tuberculosis
A Trial of Radial EBUS Versus VBN for the Peripheral Pulmonary Lesions
Peripheral pulmonary lesions are of growing importance in respiratory field. Early detection of lung cancer, tuberculosis and other diseases often needs a bronchoscopic investigation with different types of navigation.
- Conditions
- Lung Cancer, Tuberculosis, Pneumonia
- Trial name
- NCT05739695
- Testing
- Virtual bronchoscopy navigation, radial EBUS
- Where
- 6 sites in Russia
- Volunteers
- 118 people
- Sponsor
- Ilya Sivokozov
Non Small Cell Lung Cancer
OPTIMISE Lung SABR
This study is a phase II multi-centre, randomised study independently evaluating five fraction Image-Guided Stereotactic Ablative Radiotherapy (IG-SABR) and three fraction IG-SABR for patients with a peripherally located T1-T2…
- Trial name
- NCT07777614
- Testing
- Five fraction Image-guided Stereotactic Ablative Radiotherapy (IG-SABR) treatment, Investigational three fraction image-guided Stereotactic Ablative Radiotherapy (IG-SABR)
- Where
- Ireland
- Volunteers
- 208 people
- Sponsor
- Cancer Trials Ireland
Lung Nodule, Lung Mass
Cone Beam CT Guided Electromagnetic Navigational Bronchoscopy
Electromagnetic navigation bronchoscopy (ENB) is used to access peripheral and central parenchymal lung lesions via endobronchial and transbronchial approach.
- Conditions
- Lung Nodule, Lung Mass, Lesion of the Lung
- Trial name
- CBCTENB (NCT04194333)
- Testing
- Cone Beam CT with Embo Guide to creat 3D Overlay and CT Augmented Fluoroscopy to guide Electromagnetic Navigational Bronchoscopy instead of Standard Fluroscopic guidance using the C-Arm
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Columbus Regional Health
AI (Artificial Intelligence), Mammary Cancer
Experiment on the Use of Innovative Computer Vision Technologies for Analysis of Medical Images in the Moscow Healthcare System
It is planned to integrate various services based on computer vision technologies for analysis of the certain type of x-ray study into Moscow Unified Radiological Information Service (hereinafter referred to as URIS).
- Conditions
- AI (Artificial Intelligence), Mammary Cancer, Lung Cancer, X-Rays; Lesion
- Trial name
- NCT04489992
- Where
- Russia
- Volunteers
- 133,000 people, healthy volunteers welcome
- Sponsor
- Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
Atrial Fibrillation
Randomized Trial of Two Different Strategies to Treat Paroxysmal Atrial Fibrillation
The purpose of this study is to investigate the significance of complete versus incomplete electrical isolation of pulmonary veins by radiofrequency-induced linear lesions in patients with paroxysmal atrial fibrillation.
- Trial name
- NCT00293943
- Testing
- Pulmonary vein ablation
- Where
- 3 sites in Germany
- Volunteers
- 232 people
- Sponsor
- Atrial Fibrillation Network
Transbronchial Biopsies, Peripheral Lung Lesion
Predictive Diagnostic Criteria for Diagnosis of Transbronchial Biopsies, Echo-guided by Mini-probe in Peripheral Lung Lesions
The diagnosis of nodules and peripheral lung masses (lesions not accessible in classical bronchial endoscopy) is a challenge for the pulmonologist especially when these lesions are not accessible to the transparietal aspirate…
- Trial name
- EBUS-R-PTB (NCT03132870)
- Testing
- Define predictive criteria for the diagnostic performance of echo-guide samples by mini-probe in peripheral lung lesions
- Where
- France
- Volunteers
- 66 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Dementia, Parkinson Disease
Data Collection Study for the Spectrum Dynamics Multi-purpose CZT SPECT Camera
This study evaluates SPECT image data acquired from Spectrum Dynamics' multi-purpose CZT SPECT-CT camera. All subjects will undergo routine clinical Anger SPECT imaging and an additional SPECT acquisition on the CZT SPECT camera.
- Conditions
- Dementia, Parkinson Disease, Pulmonary Hypertension, Heart Diseases
- Trial name
- NCT03438123
- Testing
- CZT SPECT imaging
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Spectrum Dynamics
Lung Nodule, Solitary, Lung Nodule
Iriscope for the Diagnosis of Peripheral Pulmonary Lesions: a Multicentre Randomised Controlled Trial
A pulmonary nodule is a small mass detected in your lungs during a scan. When a nodule is suspicious, we need to determine its nature (benign or malignant). To do this, a bronchoscopy is performed.
- Conditions
- Lung Nodule, Solitary, Lung Nodule, Lung Cancer (Diagnosis)
- Trial name
- NCT07798362
- Testing
- Use of Iriscope via guide sheath to guide biopsies, Bronchoscopy
- Volunteers
- 140 people
- Sponsor
- Erasme University Hospital
Lung Cancer
ENB-GS-TBLB for the Diagnosis of PPLs
The purpose of this study is to evaluate the efficacy and safety of electromagnetic navigation bronchoscopy with a Guide Sheath(ENB-GS) for the diagnosis of peripheral pulmonary lesions (PPLs) .
- Trial name
- NCT02207478
- Testing
- ENB, GS-TBLB-X-ray
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Shanghai Chest Hospital