Clinical trials: Levonorgestrel
Contraception
Metabolism Study to Investigate the Impact of a Sequential Oral Contraceptive
The purpose of this study is to confirm the safety of SH T00658ID with regard to plasma lipids, hemostatic variables, and carbohydrate metabolism.
- Trial name
- NCT00185224
- Testing
- EV/DNG (Qlaira, BAY86-5027, SH T00658K), SH D00264A (Triquilar)
- Where
- Germany
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Bayer
Contraception, Libido
Effects of SH T00658ID on Libido
The aim of the study is to investigate whether women on oral contraceptives (OCs) suffering from acquired OC-associated female sexual dysfunction (FSD) for at least 3 months but no longer than one year will express the same level…
- Trial name
- NCT00764881
- Testing
- EV/DNG (Qlaira, BAY86-5027, SH T00658ID), Microgynon
- Where
- 32 sites in Australia, Austria and 5 more
- Volunteers
- 217 people
- Sponsor
- Bayer
Contraception
A Multi-center, Open-label, Randomized, Parallel Group Study to Evaluate Pharmacokinetic Profile, Effects on the Mechanisms of Contraceptive Efficacy and Safety of Two Progestin-only Patches Containing Different Doses of Levonorgestrel (LNG)
WHAT IS THE STUDY PRODUCT? The study product is a contraceptive patch, which has the study drug on the patch. The patch is applied directly to the skin and it contains Levonorgestrel (LNG) in a time-release form.
- Trial name
- CCN009 (NCT01166412)
- Testing
- levonorgestrel patch with BMI 32 kg/m2 to <40 kg/m2, levonorgestrel patch with BMI <32 kg/m2
- Where
- 6 sites in United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Premier Research
Contraception
A Study to Compare the Menstrual Bleeding Profile Among Jaydess® and Copper Intrauterine Device (IUD) Users. COLIBRI STUDY (Copper and Levonorgestrel IUD Barcelona Research Initiative).
The intrauterine device (IUD) is a long-term birth control method that has demonstrated high contraceptive efficacy and effectiveness due to its high compliance, adherence and persistence of use.
- Trial name
- COLIBRI (NCT02957292)
- Testing
- Levonorgestrel (13,5 mg) intrauterine device, Cooper (380mm2) intrauterine device
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Contraception, Menorrhagia
Mirena Observational Program
Mirena is used for long-term in Kazakhstan, and in our observational program we would like to study patients distribution per indications of Mirena, and also patient compliance within a year after Mirena insertion.
- Conditions
- Contraception, Menorrhagia, Endometrial Hyperplasia, Estrogen Replacement Therapy
- Trial name
- NCT00883662
- Testing
- Levonorgestrel (Mirena, BAY86-5028)
- Where
- Kazakhstan
- Volunteers
- 2,725 people
- Sponsor
- Bayer
Endometrial Cancer
Mirena® ± Metformin as Fertility-preserving Treatment for Young Asian Women With Early Endometrial Cancer
Primary objective To discover the efficacies of levonorgestrel-containing intrauterine device (LNG-IUS, Mirena®), with or without metformin, as fertility-preserving treatment for grade 1 endometrioid adenocarcinoma of…
- Trial name
- NCT02990728
- Testing
- Metformin, Mirena®
- Volunteers
- 120 people
- Sponsor
- Chang Gung Memorial Hospital
Contraception
Levonorgestrel Contraceptive Intrauterine Systems (LCS) Pearl Index Study
This is a study on a new low dose levonorgestrel contraceptive intrauterine systems (LCS). The purpose of the study is to investigate which of the 2 administered doses is the lowest effective intrauterine dose of Levonorgestrel…
- Trial name
- NCT00528112
- Testing
- LCS12, LCS16
- Where
- 136 sites in United States, Argentina and 9 more
- Volunteers
- 2,885 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy Participants
A Study of Elenestinib in Healthy Adult Female Participants
The main objectives of this study are to determine the effect of elenestinib on the pharmacokinetic parameters (how the drug is absorbed, distributed, and processed by the body) of midazolam, and to determine the effect of…
- Trial name
- NCT07388511
- Testing
- Elenestinib, Midazolam, Levonorgestrel/Ethinyl Estradiol
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Blueprint Medicines Corporation
HIV
Pharmacokinetic Effect of Evotaz/Microgynon Co-administration
This study will investigate the pharmacokinetic of evotaz (atazanavir/cobicistat) and microgynon (ethinylestradiol/levonorgestrel ) when administered alone and together.
- Trial name
- NCT02697851
- Testing
- Microgynon 30®, Evotaz®
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- St Stephens Aids Trust
Atypical Endometrial Hyperplasia
Megestrol Acetate Plus LNG-IUS in Young Women With Endometrial Atypical Hyperplasia
To see if megestrol acetate plus Levonorgestrel-releasing intrauterine system (LNG-IUS) will not be inferior to returning the endometrial tissue to a normal state than megestrol acetate or LNG-IUS alone in patients with…
- Trial name
- NCT03241888
- Testing
- Megestrol Acetate, Levonorgestrel-releasing Intrauterine System(LNG-IUS)
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Fudan University
Endometrial Hyperplasia
Mirena for the Treatment of Nonatypical Endometrial Hyperplasia for 6 Months
Researchers are looking for a better way to treat women with nonatypical endometrial hyperplasia (NAEH). Endometrial hyperplasia is a condition where the lining of the uterus (called the endometrium) becomes too thick.
- Trial name
- SUNFLOWER (NCT06904274)
- Testing
- BAY865028, Medroxyprogesterone acetate
- Where
- 38 sites in United States, Canada and 1 more
- Sponsor
- Bayer
Healthy
AZD6140 Oral Contraceptive Interaction Study
The purpose of this study is to examine the effect of co-administration of AZD6140 and Nordette® on the blood levels of certain female hormones.
- Trial name
- NCT00685906
- Testing
- AZD6140, Levonorgestrel and Ethinyl Estradiol (Nordette®)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Contraception
Immediate Postpartum Insertion of Contraceptive Intrauterine Devices
In this randomized trial, investigators intend to determine the expulsion and discontinuation rate of immediate postpartum intrauterine devices in the patient population of the University of Oklahoma Women's Healthcare…
- Trial name
- NCT03657602
- Testing
- Kyleena Intrauterine System, Mirena Intrauterine System
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Levonorgestrel Adverse Reaction, Temporomandibular Joint Disorders
Temporomandibular Disorder in Use of Levonorgestrel Intrauterine System
The goal of this clinical trial is to investigate the possible role of levonorgestrel intrauterine system use(LIU) in the pathogenesis of temporomandibular joint disorder (TMD).
- Conditions
- Levonorgestrel Adverse Reaction, Temporomandibular Joint Disorders, Temporomandibular Disorder
- Trial name
- NCT06500390
- Testing
- Examination of temporomandibular joint and masticator muscles
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Contraception
Pearl Index Study With Low Dose Combined Oral Contraceptive
The purpose of this study is to investigate the contraceptive efficacy, bleeding pattern, and safety of SH D00342A. Subjects participating in the study will be treated with an oral contraceptive pill containing 0.03 mg…
- Trial name
- NCT00220324
- Testing
- Minisiston (SH D00342A)
- Where
- 25 sites in Germany
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy Volunteer
A Study of Aleglitazar in Combination With Oral Contraceptive Healthy Volunteers
This randomized, double-blind, placebo-controlled, cross-over study will assess the effect of aleglitazar on the pharmacokinetics and pharmacodynamics on Microgynon® in healthy volunteers.
- Trial name
- NCT01615354
- Testing
- Aleglitazar, Microgynon®
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Endometrial Polyp
The Effect of Levonorgestrel Intrauterine System in Preventing Endometrial Polyps Recurrence
The goal of this clinical trial is to determine whether the LNG-IUS is more effective to that of expectant in preventing endometrial polyp recurrence after hysteroscopic polypectomy.
- Trial name
- NCT06620939
- Testing
- Levonorgestrel Intrauterine System (LNG-IUS)
- Volunteers
- 558 people
- Sponsor
- Zhang Jian
Endometrial Cancer
Treatment With Medroxyprogesterone Acetate Plus LNG-IUS in Young Women With Early Stage Endometrial Cancer
A prospective multicenter trial has been started in Korea to investigate the treatment efficacy of Levonorgestrel-releasing intrauterine system (LNG-IUS) plus Medroxyprogesterone Acetate(MPA) in Young Women with Early Stage…
- Trial name
- NCT01594879
- Testing
- MIrena(LNG-IUS), oral MPA
- Where
- South Korea
- Volunteers
- 39 people
- Sponsor
- Korean Gynecologic Oncology Group
Overweight, Obesity
A Research Study Looking Into How NNC0662-0419 Works With Birth Control Pills and Emptying of the Stomach in Women Not Able to Become Pregnant With Excess Body Weight
The purpose of this clinical study is to find out if NNC0662-0419 is safe and effective to be taken together with other medicines, like birth control pills, and emptying of the stomach in women not able to become pregnant living…
- Trial name
- NCT07525791
- Testing
- NNC0662-0419, Oral contraceptive, Acetaminophen
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Diabetes, Diabetes Mellitus, Type 2
Influence on the Effect of an Oral Contraceptive Drug After Administration of Liraglutide in Postmenopausal Women
This trial is conducted in Europe. The aim of this trial is to investigate if liraglutide changes AUC (area under the curve) of ethinylestradiol and levonorgestrel administered as a combination contraceptive drug (Neovletta®).
- Trial name
- NCT01508858
- Testing
- liraglutide, levonorgestrel / ethinylestradiol
- Where
- Sweden
- Volunteers
- 21 people
- Sponsor
- Novo Nordisk A/S