Clinical trials: Lidocaine
Dermal Fillers, Lidocaine
The Clinical Trial of Difference Between Formaderm Lidocaine and Formaderm Dermal Filler Injection
The goal of this clinical trial is to evaluate the safety and efficacy of Formaderm Lidocaine to the correction of nasolabial folds wrinkle and reduction of pain immediately after treatment.
- Conditions
- Dermal Fillers, Lidocaine, Hyaluronic Acid
- Trial name
- NCT05935449
- Testing
- Formaderm Lidocaine, Formaderm Dermal Filler Injection
- Where
- 2 sites in Taiwan
- Volunteers
- 42 people
- Sponsor
- Maxigen Biotech Inc.
Analgesia
Cocaine, Lidocaine/xylometazoline and Saline for Nasal Analgesia
When performed by trained personnel nasotracheal intubation is a safe and effective technique for attaining a secure airway in preparation for surgery of the head and neck.
- Trial name
- NCT06443255
- Testing
- Cociane hydrochloride 4%, Lidocaine 4%, Xylometazoline 0.1%
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Anesthetics, Local
Split Face Study of the Duration of Local Anesthetics
This is a research study to compare how long injectable pain medications (anesthetics) commonly used in dermatologic surgery are effective for.
- Trial name
- NCT05767749
- Testing
- lidocaine + epinephrine 1:100,000, Ropivacaine 0.5% Injectable Solution, Bupivacaine 0.5% Injectable Solution
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Anesthesia, General Anesthesia
Effect of Multimodal Opioid-free Anesthesia on Return of Bowel Function in Laparoscopic Colorectal Surgery
The objective of this study is to determine if an opioid-free general anesthetic (OFA) technique utilizing lidocaine, ketamine, dexmedetomidine and magnesium reduce postoperative opioid consumption and speed return of bowel…
- Conditions
- Anesthesia, General Anesthesia, Analgesics, Opioid, Opioid Free Anesthesia
- Trial name
- RUMBLE (NCT04144933)
- Testing
- Acetaminophen, Gabapentin, Lidocaine 1% Injectable Solution, Dexmedetomidine, Ketamine, Dexamethasone, Ondansetron
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Saskatchewan
Healthy, Inflammation
Using a Narcotic to Enhance the Numbing Effect of the Local Anesthetic Lidocaine on Inflamed Molar Teeth
The effectiveness of local anesthetics is reduced if inflammation is present, making it difficult to control pain during such procedures as root canals and wisdom teeth removal.
- Conditions
- Healthy, Inflammation, Mouth Disease, Pain
- Trial name
- NCT00001952
- Where
- United States
- Volunteers
- 275 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
FESS Operation
Intratracheal Dexmedetomidine Versus Lidocaine for Smooth Tracheal Extubation
compare the efficacy of intratracheal dexmedetomidine versus intratracheal lidocaine in achieving smooth tracheal extubation in patients undergoing Functional Endoscopic Sinus surgery and reconstructive nasal surgeries under…
- Trial name
- NCT07504497
- Testing
- dexmedetomidine Lidocaine Saline
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Younes Ahmed Younes
Postoperative Pain
Effect of Transversus Abdominis Plane Block With Compound Lidocaine and Esketamine on Pain After Surgery
Purpose: To explore effects of ultrasound-guided transversus abdominis plane block with compound lidocaine and esketamine on postoperative pain after colorectal cancer surgery.
- Trial name
- NCT05122338
- Testing
- Normal saline, Ropivacaine, Compound lidocaine
- Volunteers
- 160 people
- Sponsor
- Tianjin Medical University General Hospital
Pain, Post Operative, Pain, Acute
Opioid-free Anesthesia in Thyroidectomies
The aim of this study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of dexmedetomidine-lidocaine-ketamine in the same syringe versus fentanyl analgesia in elective thyroidectomies.
- Conditions
- Pain, Post Operative, Pain, Acute, Pain, Chronic, Pain, Neuropathic
- Trial name
- NCT05243940
- Testing
- dexmedetomidine-ketamine-lidocaine (DKL), remifentanil infusion
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Aretaieion University Hospital
Dermal Filler, Hyaluronic Acid
The Evaluation of the Safety and Effectiveness of a Novel Gel-type Sodium Hyaluronate for the Correction of Aging Mid-face
This study is to evaluate the safety and effectiveness for the correction of aging mid-face of treatment group compared with the negative control group.
- Conditions
- Dermal Filler, Hyaluronic Acid, Lidocaine, Aging Mid-Face
- Trial name
- NCT04599335
- Testing
- 2% HA
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- SciVision Biotech Inc.
Infraorbital Hollowing
A Study to Evaluate the Safety and Effectiveness of Injectable Gel for Correction of Infraorbital Hollowing in Chinese Population
A Multicenter, Evaluator-blinded, Randomized, No-treatment Controlled Study to Evaluate the Safety and Effectiveness of MAILI PRECISE With Lidocaine Injectable Gel for Correction of Infraorbital Hollowing in Chinese Population
- Trial name
- NCT06394076
- Testing
- Cross-linked sodium hyaluronate gel for injection containing lidocaine
- Where
- China
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Sinclair Pharmaceuticals Limited
Diabetic Nerve Problems, Diabetic Neuropathy
The Efficacy and Safety Profile of Capsaicin 8% Patch Versus 5% Lidocaine Patch in Males With Diabetic Neuropathy
The study aims to compare the effectiveness and tolerability of using lidocaine 5% patch to 8% capsaicin patch in patients with diabetic neuropathy.
- Conditions
- Diabetic Nerve Problems, Diabetic Neuropathy, Diabetic Complications Neurological
- Trial name
- NCT04238208
- Testing
- Lidocaine 5% patch, Capsaicin 8% Patch, Per 10 Square Centimeters
- Where
- Pakistan
- Volunteers
- 290 people
- Sponsor
- Corporacion Parc Tauli
Irreversible Pulpitis (Toothache)
Effect of Buffered Numbing Solution on Patients With Toothaches
The purpose of this study is to determine the effect of buffered lidocaine (a numbing solution) on the ability to numb patients with toothaches.
- Trial name
- NCT01868776
- Testing
- buffered lidocaine, nonbuffered lidocaine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ohio State University
Nasolabial FOLD
To Evaluate the Efficacy and Safety of Injection With HARA as Compared to Restylane® Lidocaine in Temporary Correction of Nasolabial Folds
Investigational Device : HARA (Hyaluronic Acid Filler) Title : A Single center, Randomized, Subject \& Evaluator-blind, Matched pairs, Active-controlled design Pivotal study to Evaluate the Efficacy and Safety of Injection with…
- Trial name
- NCT04224649
- Testing
- HARA Filler(Hyaluronic acid Filler), Restylane® Lidocaine
- Where
- South Korea
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Huons Co., Ltd.
Paracervical Block
Paracervical Block During Office Hysteroscopy
The purpose of this study is to determine the effectiveness of paracervical block for pain relief in office hysteroscopy - particularly with the placement of the Essure device.
- Trial name
- NCT00811187
- Testing
- Lidocaine paracervical block, Normal Saline
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Postoperative Pain Management
Low-Dose Lidocaine Infusion for Acute Pain Management Pilot Study
The purpose of this study is to evaluate the safety and efficacy of lidocaine infusion in acute pain management following open abdominal surgery, including opiate use after surgery and the incidence of postoperative nausea and…
- Trial name
- NCT06725485
- Testing
- Low-Dose Lidocaine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- The Methodist Hospital Research Institute
Lumbar Fusion Surgery
Intravenous Lidocaine Infusion in Lumbar Fusion Surgery
Elective lumbar fusion surgery is associated with moderate to severe postoperative pain and often requires substantial perioperative opioid administration.
- Trial name
- NCT07488832
- Testing
- Lidocaine, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Ankara City Hospital Bilkent
Postoperative Pain
Percutaneous Ketamine Versus Lidocaine or Placebo, for Post-Surgery Analgesia, in Patients Undergoing Laparoscopic Partial Lung Resection
Since VAT bears with it severe postopearive pain, and since ketamine has been shown to be an optimal analgesics adjuvant for postoperative pain, we wish to assess to effects of ketamie vs.
- Trial name
- NCT00822133
- Testing
- lidocaine, ketamine, non-active drug cream
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pain, Surgical Abortion
Paracervical Block in First Trimester Surgical Abortions
The investigators primary objective is to study the analgesic effects of combined ketorolac and lidocaine in a paracervical block compared to preoperative ibuprofen followed by intra-operative paracervical block with lidocaine…
- Trial name
- NCT00617097
- Testing
- lidocaine, ketorolac and lidocaine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Pain
Comparison of Lidocaine-Prilocaine Combination and Vapocoolant for IV Cannulation Pain in the ED
Hypothesis: Lidocaine-Prilocaine Combination is as effective as Vapocoolant in treating IV cannulation pain in the emergency department.
- Trial name
- NCT04473820
- Testing
- Vapocoolant spray, Lidocaine-Prilocaine cream
- Where
- Iran
- Volunteers
- 77 people
- Sponsor
- Tehran University of Medical Sciences
Skin Aging of Dorsal Hands
Comparing Pain, Safety and Effectiveness of Restylane Skinboosters Vital Lido and Vital Without Lido in Dorsal Hand
This is a randomized, multi-center, split-hand, subject-blinded study comparing pain, safety and effectiveness of Restylane Skinboosters Vital Lidocaine and Restylane Vital without lidocaine for improving appearance of the dorsal…
- Trial name
- NCT06372782
- Testing
- Restylane Skinboosters Vital Lidocaine, Restylane Vital
- Where
- 3 sites in China
- Volunteers
- 90 people
- Sponsor
- Galderma R&D