Clinical trials: Lifestyle
Obesity, Overweight
A Study of Tirzepatide (LY3298176) In Participants After A Lifestyle Weight Loss Program
This is a study of tirzepatide in participants with obesity. The purpose of this study is to learn more about how tirzepatide maintains body weight or adds to weight loss after an intensive lifestyle modification program.
- Trial name
- SURMOUNT-3 (NCT04657016)
- Testing
- Tirzepatide
- Where
- 65 sites in United States, Argentina and 2 more
- Volunteers
- 579 people
- Sponsor
- Eli Lilly and Company
PreDiabetes
Efficacy and Safety of Digital Therapeutic in Adults With Prediabetes
The study aims to evaluate the efficacy and safety of a digital therapeutic (TH-001) for adult individuals with prediabetes.
- Trial name
- NCT05668819
- Testing
- TH-001
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Tesu Saglik Teknolojileri A.S.
Sedentary Lifestyle, Physical Activity
Evaluating the Impact of Personalized Move Goals on Physical Activity
The purpose of this study is to evaluate the impact of personalized move goals in the Welltory mobile app on daily step count among adults from 30 to 65 years old.
- Trial name
- NCT05123989
- Testing
- Personalized move goals, Constant move goals
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Welltory Inc.
Type 2 Diabetes Mellitus (T2DM)
Cohort Study Evaluating Glycaemic Control in Individuals with Type 2 Diabetes Mellitus Through Digital Therapeutics (DM DTx)
This study is conducted to evaluate the effectiveness of Digital therapeutics (DTx) in managing patients with Type 2 Diabetes Mellitus (T2DM) by delivering digital lifestyle interventions through a national health application…
- Trial name
- DM DTx (NCT06810986)
- Testing
- 16-week digital intervention
- Where
- Brunei
- Volunteers
- 500 people
- Sponsor
- EVYD Technology
GERD, Quality of Life
The Effect of Lifestyle-Adjustments Prior to Medical Treatment on the Effect of Medical Treatment in Reflux Patients
The purpose of this study is to determine whether the improvement in the quality of life after an initial treatment with esomeprazole 40mg for reflux disease is the same in patients who have already made lifestyle-adjustments as…
- Trial name
- NCT00524251
- Testing
- esomeprazole
- Where
- 54 sites in Netherlands
- Volunteers
- 990 people
- Sponsor
- AstraZeneca
Diabetes Mellitus, Type 2, Metagenome
Study of the Genome, Gut Metagenome and Lifestyle of Patients With Incident Type 2 Diabetes Mellitus
A case-control study to identify microbiome and genetic differences between healthy people and patients with incident type 2 diabetes mellitus.
- Conditions
- Diabetes Mellitus, Type 2, Metagenome, Genetic Predisposition
- Trial name
- NCT04113239
- Testing
- 16S rRNA gene sequencing, DNA-microarray genotyping
- Where
- Russia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Atlas Biomed
Health, Subjective, Gastrointestinal Dysfunction
Personalized Lifestyle Intervention for Improving Functional Health Outcomes Using N-of-1 Tent-Umbrella-Bucket Design
The LIFE-HOUSE research project is designed to evaluate the impact of a personalized lifestyle intervention program on functional capacity as an approach to quantitating health, and its relationship to well understood disease…
- Conditions
- Health, Subjective, Gastrointestinal Dysfunction, Cardiovascular Risk Factor, Autoimmune Diseases
- Trial name
- LIFE-HOUSE (NCT04005456)
- Testing
- Supplements and/or medical foods, Behavioral change support program, Food plan
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Metagenics, Inc.
Nonalcoholic Steatohepatitis, Insulin Resistance
Efficacy and Safety of Diamel in Patients With Nonalcoholic Steatohepatitis
The purpose of the study is to evaluate whether the addition of Diamel, a nutritional supplement, to hypocaloric diet and exercise could improve the histological results (steatosis, necro-inflammatory activity and fibrosis)…
- Trial name
- NCT00820651
- Testing
- Diamel
- Where
- Cuba
- Volunteers
- 158 people
- Sponsor
- Catalysis SL
Hypertension, Obesity
Observational Non-interventional Study (Anwendungsbeobachtung) With Telmisartan in High-risk Hypertensives
This observational non-interventional study will assess (under conditions of clinical practice in daily routine) the antihypertensive efficacy of telmisartan treatment with or without active promotion of lifestyle changes in…
- Trial name
- NCT00539487
- Where
- 2,389 sites in Germany
- Volunteers
- 5,827 people
- Sponsor
- Boehringer Ingelheim
PreDiabetes
Prevention of Microvascular Complications in Prediabetes e-PREDICE Study
Background: A significant proportion of pre-diabetics, show macro and micro vascular complications associated with hyperglycaemia.
- Trial name
- ePREDICE (NCT03222765)
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Evidem Consultores SL
Hypercholesterolemia
Rosuvastatin ORBITAL Germany
The primary objective of the study is to compare the effect of rosuvastatin therapy plus compliance initiatives and rosuvastatin therapy alone for 12 months (52 weeks) on long-term cumulative direct and indirect disease-related…
- Trial name
- NCT00379249
- Testing
- Rosuvastatin
- Volunteers
- 8,000 people
- Sponsor
- AstraZeneca
Obesity
Safety Evaluation of a Lifestyle Modification Program In.Form 1.1
The study evaluated and compared the safety, tolerance and acceptability of a lifestyle modification program with or without nutritional supplementation in generally healthy overweight subjects with cardiometabolic risk factors.
- Trial name
- NCT03097965
- Testing
- PROGRAM, DIET
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Nature's Sunshine Products, Inc.
Non Alcoholic Fatty Liver Disease
A Digital Solution for Individuals With Non Alcoholic Fatty Liver Disease
Sidekick Health has developed a digital behavioral change program (SK-241) specifically designed for people with metabolic derangements and non-alcoholic fatty liver disease (NAFLD).
- Trial name
- NCT05426382
- Testing
- A digital care solution for patients with NAFLD
- Where
- 2 sites in Iceland
- Volunteers
- 38 people
- Sponsor
- Sidekick Health
Obesity &Amp;Amp;Amp; Overweight, Environmental Exposure
Weight Loss and Endocrine Disrupting Chemicals (EDCs): Lifestyle Interventions to Lose Weight and Reduce EDC Exposure in Individuals With Overweight/Obesity
The goal of this study is to examine the relationship in individuals with overweight/obesity and endocrine disrupting chemical (EDC) exposure through a two-armed, randomized clinical trial.
- Conditions
- Obesity &Amp;Amp;Amp; Overweight, Environmental Exposure, Overweight (BMI > 25)
- Trial name
- LiveWell (NCT07560579)
- Testing
- Educational curriculum, Weight loss Application, Urinary EDC metabolite testing
- Where
- United States
- Volunteers
- 226 people
- Sponsor
- Million Marker Wellness, Inc.
Diabetes Mellitus, Type 2
Effects of LY2189265 on Glycemic Control in Participants With Type 2 Diabetes
This is a study to demonstrate that different doses of once-weekly LY2189265 injected subcutaneously will have dose proportional effect on hemoglobin A1c (HbA1c) at 12 weeks in participants with type 2 diabetes mellitus.
- Trial name
- NCT00791479
- Testing
- LY2189265 and Lifestyle Measures
- Where
- 46 sites in United States, Croatia and 7 more
- Volunteers
- 167 people
- Sponsor
- Eli Lilly and Company