Clinical trials: Lifestyle Risk Reduction
Cardiovascular Disease
CVD Risk Reduction Trial
The purpose of this study is to provide lifestyle counselling for protective health behavior (exercise, diet, smoking cessation) to small groups (6-8 subjects) via teleconference.
- Trial name
- COHRT (NCT00473785)
- Testing
- Group-based motivational interviewing, Individual CVD-risk factor feedback, Education for protective health behavior change
- Where
- 3 sites in Canada
- Volunteers
- 827 people
- Sponsor
- University Health Network, Toronto
Lifestyle Risk Reduction, Cholesterol, Elevated
Effect of a Customised Lifestyle Medicine Strategy on Lowering Blood Lipid Levels in Indian Physicians
Lifestyle medicine is a medical specialty that uses evidence-based therapeutic interventions to prevent, treat, and reverse chronic conditions.
- Conditions
- Lifestyle Risk Reduction, Cholesterol, Elevated, LDL Hyperlipoproteinemia, Hypertension
- Trial name
- CLIP (NCT06420817)
- Testing
- Indian version of a 'Portfolio' diet, Physical Activity, Intermittent fasting
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jubilee Mission Medical College and Research Institute
Lifestyle Risk Reduction, Rheumatoid Arthritis
Lifestyle Intervention for Rheumatoid Arthritis
The main purpose of this study is to assess whether adding a multifaceted lifestyle intervention to the standard best practice of care can be more effective than standard best practices alone for treating Rheumatoid Arthritis.
- Trial name
- NCT05554705
- Testing
- Intensive Lifestyle intervention
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Blue Cross Blue Shield of Vermont
Abdominal Obesity
Effects of Weight Reduction on Sleep and Alertness in Long-distance Truck and Bus Drivers
The study is a year-long health-behaviour intervention in obese, male truck-drivers to lose weight moderately by 10%, using monthly individual counseling.
- Trial name
- SF-Truck (NCT00893646)
- Testing
- weight loss counseling
- Where
- 3 sites in Finland
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Weight Loss, Diabetes Mellitus, Type 2
Reducing Weight and Diabetes Risk in an Underserved Population (STRIDE)
The purpose of this study is to examine the effectiveness of a lifestyle intervention designed to reduce weight and diabetes risk in a population of individuals with mental illness who are also taking antipsychotic medications.
- Conditions
- Weight Loss, Diabetes Mellitus, Type 2, Psychotic Disorders
- Trial name
- STRIDE (NCT00790517)
- Testing
- Premier Lifestyle Intervention with DASH Diet
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Kaiser Permanente
Opiate Dependence, HIV Infections
HIV Risk Reduction and Drug Abuse Treatment in Iran
A randomized, double blind clinical trial comparing buprenorphine and naltrexone maintenance treatment when combined with drug abuse and HIV risk reduction counseling (DC-HIV) for heroin and opium addicts in Iran.
- Trial name
- NCT00398008
- Testing
- Buprenorphine/Subutex, Naltrexone, Drug counseling
- Where
- 2 sites in United States, Iran
- Sponsor
- Yale University
Smoking
Combined Treatment for Tobacco and Alcohol Use in Puerto Rico
Objectives: 1. Assess MAPS and MAPS+ effects on alcohol at-risk behaviors and smoking cessation. 2. Assess MAPS and MAPS+ effects on treatment mechanisms (increased self-efficacy, decreased temptations/craving, decreased stress…
- Trial name
- NCT00570804
- Testing
- Telephone Counseling, Telephone Assessments
- Where
- United States
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
High Risk for Breast Cancer, Risk Reduction Behavior
Facilitating Web-based Patient Decision Support: Decision About Medication to Lower Breast Cancer Risk
Background: Chemoprevention is the use of preventive medications to reduce the risk of breast cancer for women who are at a high risk of developing the disease.
- Trial name
- NCT00906321
- Testing
- Web-Based Decision Support
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- National Cancer Institute (NCI)
HIV, HIV Infections
Positive Lifestyles Using Safety
Project PLUS tests an HIV risk reduction/adherence behavioral intervention with HIV-infected individuals in Connecticut prisons.
- Trial name
- Project PLUS (NCT00836290)
- Testing
- Pre-Release (Group 1), Post-release (Group 2)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Yale University
HIV Prevention, Pre-exposure Prophylaxis (PrEP)
A Study Evaluating An Integrated Pharmacy Digital Diary and Delivery Strategy to Increase PrEP Use Among MSM and TGW
The PrEP 3D randomized controlled trial (RCT) will study the effectiveness of the PrEP-3D app compared to standard of care for starting pre-exposure prophylaxis (PrEP), continuing PrEP, and adherence to PrEP.
- Conditions
- HIV Prevention, Pre-exposure Prophylaxis (PrEP), Risk Reduction, Adherence, Medication
- Trial name
- PrEP-3D RCT (NCT05474313)
- Testing
- PrEP-3D package, Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Public Health Foundation Enterprises, Inc.
Opioid-Related Disorders
The OPT-IN Project
Prescription opioid overdose represents a public health crisis. A number of efforts have been implemented to address opioid prescribing and opioid risk mitigation strategies for prescribers, but relatively few efforts have sought…
- Trial name
- NCT03526380
- Testing
- Behavioral: the OPT-IN Intervention
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of Michigan
Life Style, Healthy, Risk Reduction
Digital Engagement for Lifelong Health
The DELPHI project (Digital Engagement for Lifelong Prevention and Health Improvement) aims to develop, implement, and validate an advanced digital platform for promoting well-being and personalized prevention of chronic…
- Conditions
- Life Style, Healthy, Risk Reduction, Health Promotion
- Trial name
- DELPHI (NCT07612852)
- Testing
- DELPHI Personalized Digital Prevention Platform, Passive Digital Monitoring Control
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Life Style, Healthy, Life Style
A Randomized-Controlled Lifestyle Intervention to Increase Physical Activity Levels in Adolescents
Students at the age of 14-16 years will be randomized to one intervention arm or one control arm in a 1:1 ratio. Participants of both groups receive a fitness tracker to count the amount of their steps taken.
- Trial name
- healthy tyrol (NCT04749004)
- Testing
- Promotion of physical activity
- Where
- Austria
- Volunteers
- 373 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
Child Rearing, Adolescent Development
Follow-up of Families in Early Preventive Intervention
This project supports the post-third-grade assessment of 693 children and their families who were enrolled in a randomized trial of a program of prenatal and infancy home visitation by nurses that was epidemiologically and…
- Conditions
- Child Rearing, Adolescent Development, Reproductive Behavior, Risk Reduction Behavior
- Trial name
- MemphisYear9 (NCT00438516)
- Testing
- nurse home visitation
- Where
- United States
- Volunteers
- 627 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Risk Reduction
Salmonella Conjugates CVD 1000: Study of Responses to Vaccination With Trivalent Invasive Salmonella Disease Vaccine
This is a randomized, placebo-controlled dose-escalation study. The main purpose of this research is to test the safety and measure the immune response of the trivalent vaccine against invasive Salmonella disease.
- Trial name
- NCT03981952
- Testing
- Trivalent Invasive Salmonella Disease Vaccine (6.25 µg), Trivalent Invasive Salmonella Disease Vaccine (12 µg), Trivalent Invasive Salmonella Disease Vaccine (25 µg)
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
HIV-1 Infection, Risk Reduction
HIV Internet Sex Study: Internet-based STI/HIV Prevention for HIV+ Internet Users
The goal of this study was to empirically test a newly developed online HIV sexual risk reduction intervention (HINTS) among a representative sample of gay and bisexual men living with HIV who meet sex partners online.
- Trial name
- HINTS (NCT02887508)
- Testing
- HINTS Intervention, Healthy Living Control
- Volunteers
- 170 people
- Sponsor
- University of Connecticut
Cardiovascular Risk Factor, Lifestyle Risk Reduction
The Effect of Lifestyle Intervention on Cardiovascular Disease Risk Among Women
Patient education in lifestyle changes has a positive effect on health in individuals with cardiovascular (CV) risk. Despite current positive evidence about lifestyle and dietary change in the prevention of CVD, the…
- Trial name
- NCT04601558
- Testing
- The letters with the Cochrane abstracts in the form of blog-shots, The letters with remainder on cardiovascular risk factors
- Where
- Croatia
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Risk Reduction Behavior
Self-Affirmation: Construct Validity
Background: People respond differently when asked about their values. They also respond differently when they learn about how their actions affect their lives and health. Researchers want to learn more about these differences.
- Trial name
- NCT02317367
- Where
- United States
- Volunteers
- 3,112 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
HIV Infections, Substance Use
Reducing HIV: Safer Sex Skill Building in Pregnant Drug Abusing Women
This study will examine safer sex skills building (SSB), a targeted behavioral HIV prevention and risk reduction group intervention in two samples of pregnant drug abusing women.
- Trial name
- NCT00619320
- Testing
- Safer Sex Skills Building (SSB)
- Where
- 2 sites in United States
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Type 2 Diabetes, Obesity
Pilot Sugar Reduction Intervention in Kiritimati Teenagers
Kiritimati is an isolated coral atoll in the Pacific Ocean, and is one of 32 islands that comprise the Republic of Kiribati. Obesity and type 2 diabetes rates are high in Kiribati, but the causes and rates of childhood…
- Trial name
- NCT04319003
- Testing
- Sugar-reduction intervention
- Where
- 2 sites in United States, Kiribati
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Southern California