Clinical trials: Lifestyle-Related Condition
Hypertension, Family Relations
Walk Together: A Family-Based Intervention for Hypertension In African Americans
The goal of this study is to determine the feasibility and acceptability of a novel family-based hypertension self-management intervention, Walk Together, adapted from an existing empirically-supported dyadic intervention, for…
- Trial name
- NCT05671302
- Testing
- Walk Together
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Texas Southwestern Medical Center
Attention-deficit/Hyperactivity Disorder
Identify Peripheral Biomarkers of Symptomatology, Neurocognitive Functions, and Medication Response in ADHD
Attention deficit hyperactivity disorder (ADHD), characterized by inattention, hyperactivity and impulsivity, is an early onset, highly heritable, clinically heterogeneous, long-term impairing disorder with tremendous impact on…
- Trial name
- NCT02074228
- Testing
- Methylphenidate (Concerta)
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
Evaluation of the Effect and Safety of Lisdexamfetamine in Children Aged 6-12 With ADHD and Autism
The purpose of this study is to evaluate the effect and safety of Lisdexamfetamine dimesylate (Vyvanse®) in the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents with ADHD and comorbid…
- Trial name
- NCT03337646
- Testing
- Lisdexamfetamine Dimesylate
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- JPM van Stralen Medicine Professional
Conduct Disorder, Oppositional Defiant Disorder
Behavioral Treatment for Children With Conduct Problems and Callous-Unemotional Traits
The purpose of this study is to modify behavior therapy so that it is optimized for children with conduct problems and callous-unemotional traits by emphasizing reward components and de-emphasizing punishment components.
- Trial name
- NCT01362946
- Testing
- Reward-Emphasized Treatment, Standard Treatment
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Florida International University
Attention Deficit Hyperactivity Disorder
Role of Transcranial Direct Current Stimulation (tDCS) in Patients With Attention Deficit Hyperactivity Disorder (ADHD)
The purpose of this study is to determine whether transcranial direct current stimulation (tDCS) is effective in the treatment attention deficit hyperactivity disorder (ADHD).
- Trial name
- NCT02580890
- Testing
- tDCS active
- Where
- Brazil
- Volunteers
- 16 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Child Disruptive Behavior Disorders, Parent Child Relationship
Examining the Feasibility, Acceptability, and Fidelity of Utilizing Parent Training Graduates as Peer Supports
Disruptive behavioral disorders are common in early childhood, affecting up to 15% of preschool-aged children. Behavioral parent training programs are a first-line evidence-based treatment for child disruptive behaviors.
- Conditions
- Child Disruptive Behavior Disorders, Parent Child Relationship, Parent Management Training, Peer Support
- Trial name
- NCT06366620
- Testing
- FAST-B PEERS, FAST-B (First Approach Skills Training - Behavior)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Conduct Disorder, ADHD
Investigation of Psychophysiological Response to Aversive Stimuli Over Time With Omega-3
This study investigates the psychophysiological responses to aversive stimuli in a population of 133 children clinically diagnosed with conduct disorder (CD) and/or attention-deficit/hyperactivity disorder (ADHD).
- Conditions
- Conduct Disorder, ADHD, Oppositional Defiant Disorder
- Trial name
- NCT03749824
- Testing
- Omega-3
- Volunteers
- 133 people
- Sponsor
- Yale-NUS College
Prevention, Well Being
Troubled-Desire & Therapeutic Chat for Reduction of CSAM Use (TD-CHAT)
The goal of this prospective multicentred, stratified, parallel-group superiority study is to prevent and reduce the usage of Child Sexual Abuse Material (CSAM) by a Therapist Chat Service (TCS) and Selfhelp Platform for…
- Conditions
- Prevention, Well Being, Sexual Behavior, Behavior Change
- Trial name
- TD-CHAT (NCT06852443)
- Testing
- Selfhelp modules, Therapist Chat Service
- Where
- 2 sites in Germany, Spain
- Volunteers
- 180 people
- Sponsor
- Charite University, Berlin, Germany
Attention Deficit With Hyperactivity Disorder
Thyroid Profile in Attention Deficit With Hyperactivity Disorder (ADHD)
Rationale: The observational data of University Children's Hospitals of Nice, suggest that about a quarter of children and adolescents with ADHD may present with an abnormal thyroid profile.
- Trial name
- THYRADHD (NCT05080491)
- Testing
- immuno analysis and neuropsychological tests
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Fondation Lenval
Attention Deficit/Hyperactivity Disorder
A Trial of Centanafadine Efficacy and Safety in Children With Attention-deficit/ Hyperactivity Disorder (ADHD)
This trial will be conducted to evaluate the efficacy of centanafadine once daily (QD) extended release (XR) versus placebo in the treatment of child subjects (4 to 12 years, inclusive) with ADHD.
- Trial name
- NCT05428033
- Testing
- centanafadine capsule
- Where
- United States
- Volunteers
- 574 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
ADHD
EEG Biomarkers for ADHD Stimulant Treatment
Pediatric attention deficit hyperactivity disorder (ADHD) affects up to 10% of children in the U.S. and more than 90% are prescribed stimulant medications according to clinical guidelines.
- Trial name
- NCT07650643
- Testing
- methylphenidate HCl, Mixed amphetamine salts extended release
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Boston Children's Hospital
Neurodegenerative Diseases, Parkinson Disease
Molecular Imaging of Inflammation in Parkinson's Disease Using LPS and TSPO-PET/MR
It is not known what causes Parkinson's disease and what makes it worsen over time. Research conducted in the past few years has highlighted the possible role of inflammation on this process but its actual mechanisms are still…
- Conditions
- Neurodegenerative Diseases, Parkinson Disease, REM Sleep Behavior Disorder (iRBD)
- Trial name
- NCT05205291
- Testing
- Lipopolysaccharide, PET/MR with [11C]PBR28
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Attention Deficit Disorder With Hyperactivity
Screening for Attention-deficit/Hyperactivity Disorder (ADHD) in Adolescent and Adult High Risk Populations
This study aims to investigate the prevalence of ADHD and other psychopathology, and current function and life quality among several high risk populations of imprisoned adults and adolescents who receive special resources in…
- Trial name
- NCT00745524
- Where
- 2 sites in Taiwan
- Volunteers
- 1,910 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Attention Deficit Disorder With Hyperactivity
Effectiveness of Relaxation Technique for Behavioral Management of ADHD Children During Dental Treatment.
Evaluation of effect of relaxation technique (Muscle Relaxation) on behavioral management and anxiety control of ADHD children during dental treatment.
- Trial name
- NCT03951155
- Testing
- Muscle Relaxation
- Volunteers
- 40 people
- Sponsor
- Cairo University
Binge Drinking, Alcohol Drinking in College
Balanced Lifestyle for Undergraduate Excellence - Mobile (Project BLUEM)
The purpose of this study is to evaluate a text-message delivered approach for improving college adjustment and experience and reducing risky alcohol use in young adult college students.
- Conditions
- Binge Drinking, Alcohol Drinking in College, Behavior, Drinking, Behavior and Behavior Mechanisms
- Trial name
- BLUEM (NCT04105725)
- Testing
- Brief Motivational Intervention+Substance-Free Activity Session, Alcohol + Nutrition Education Session
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Memphis
Attention Deficit Hyperactivity Disorder, Attention Deficit Disorders With Hyperactivity
A Study to Evaluate Pharmacokinetics, Safety and Tolerability After a Single Dose Administration of of JNJ-31001074 in Children (6-11 Years) With Attention Deficit Hyperactivity Disorder (ADHD)
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (process by which JNJ-31001074 is absorbed, distributed, metabolized, and eliminated by the body) after a single dose of JNJ-31001074.
- Trial name
- NCT00890240
- Testing
- JNJ-31001074
- Volunteers
- 18 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Attention-Deficit / Hyperactivity Disorder, Depression
Prevention of Comorbid Depression and Obesity in Attention-deficit/ Hyperactivity Disorder
Depression and obesity are very common among adolescents and young adults with attention-deficit/ hyperactivity disorder (ADHD). However, intervention programmes to prevent these comorbid disorders rarely exist.
- Conditions
- Attention-Deficit / Hyperactivity Disorder, Depression, Obesity
- Trial name
- PROUD (NCT03371810)
- Testing
- Bright light therapy, Physical exercise
- Where
- 4 sites in Germany, Netherlands and 2 more
- Volunteers
- 207 people
- Sponsor
- Goethe University
Attention Deficit Disorder With Hyperactivity, Cocaine-Related Disorders
Methylphenidate Treatment for Cocaine Abuse and ADHD - 1
Many cocaine dependent individuals are also diagnosed with Attention Deficit Hyperactivity Disorder (ADHD). Methylphenidate (Ritalin) is currently approved to treat individuals diagnosed with ADHD.
- Trial name
- NCT00136734
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- New York State Psychiatric Institute
ADHD
Target ADHD Executive Working Memory Replication Study
The proposed study will replicate target engagement as assessed in the first phase while also determining if it correlates with clinically meaningful improvements in ADHD dysfunction
- Trial name
- NCT06446284
- Testing
- EWM Training
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Attention Deficit Hyperactivity Disorder
Training Executive, Attention and Motor Skills (TEAMS): Preliminary Studies
Training Executive, Attention and Motor Skills (TEAMS) is a new research program for preschool children with Attention-Deficit/Hyperactivity Disorder (ADHD) that attempts to use game-like activities and physical exercise to…
- Trial name
- TEAMS (NCT01073176)
- Testing
- TEAMS (Training Attention Executive and Motor Skills)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Queens College, The City University of New York
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