Clinical trials: Lifestyle-Related Disorder
Attention Deficit Disorder With Hyperactivity
An Efficacy Study of Osmotic Release Oral System (OROS) Methylphenidate in Participants With Attention-Deficit/Hyperactivity Disorder (ADHD)
The purpose of this study is to evaluate the efficacy, tolerability and effects of Osmotic Release Oral System (OROS) methylphenidate hydrochloride (HCl) on learning skill changes in Korean participants with Attention-Deficit…
- Trial name
- NCT01060150
- Testing
- OROS Methylphenidate HCl
- Volunteers
- 115 people
- Sponsor
- Janssen Korea, Ltd., Korea
Autism Spectrum Disorder, Attention Deficit/Hyperactivity Disorder
Evaluating the Validity of a Genetic Risk Assessment Tool in Identifying Autism Spectrum Disorder
There are three purposes to this study. The first purpose is to evaluate the value of a genetic test in determining risk for autism spectrum disorder.
- Conditions
- Autism Spectrum Disorder, Attention Deficit/Hyperactivity Disorder, Developmental Delay
- Trial name
- NCT01452061
- Where
- United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Thomas W. Frazier, Ph.D
Attention-Deficit/Hyperactivity Disorder (ADHD)
Cannabigerol Oil for Adolescents With ADHD (CAN-ADHD)
This study aims to evaluate the potential effects of full-spectrum cannabigerol (CBG) oil on cognitive and behavioral symptoms in adolescents diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD).
- Trial name
- CAN-ADHD (NCT07592390)
- Testing
- Experimental: Full-spectrum CBG oil 30 mg/mL
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Universidade do Sul de Santa Catarina
Depressive Disorder, Major, Adult Attention Deficit Hyperactivity Disorder
Clinical and Suicidal Features of Urban, Turkish Middle Age Depressive Patients With Comorbid ADHD
In the presence of attention deficit hyperactivity disorder (ADHD) together with additional psychiatric diseases, the treatment process and prognosis of both ADHD and psychiatric comorbidity are adversely affected.
- Conditions
- Depressive Disorder, Major, Adult Attention Deficit Hyperactivity Disorder, Suicide
- Trial name
- NCT03721588
- Testing
- Clinical interviews, psychometric scales were applied.
- Volunteers
- 96 people
- Sponsor
- Bozyaka Training and Research Hospital
ADHD
Online Course Teachning Adults With ADHD How to Use a Smartphone
This study is a randomized controlled trial (RCT) to evaluate the effect of an internet-based, guided self-help course for individuals who have recivied an ADHD diagnsis or struggle with organizing daily life and/or easily get…
- Trial name
- VardagsSMART (NCT01663610)
- Testing
- VardagsSMART
- Where
- Sweden
- Volunteers
- 58 people
- Sponsor
- Karolinska Institutet
Dementia With Lewy Bodies, Parkinson Disease
5-HT RBD REM Sleep Behavior Disorder
This project will test the hypotheses that people with 5-HT RBD have systemic alpha- synuclein pathology, prodromal DLB signs, and brainstem lesions in regions that control REM sleep.
- Conditions
- Dementia With Lewy Bodies, Parkinson Disease, REM Sleep Behavior Disorder
- Trial name
- NCT06467461
- Testing
- Skin biopsy, Speech testing, Ultra high field 7T MRI
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
PARKINSON DISEASE (Disorder), Parkinson
The Role of METhanogens in the PROgression Of Parkinson's Disease and Related Neurological Conditions
Gut problems, such as constipation, can have an important impact on quality of life of people who have them, and have been associated with higher risk of developing neurological diseases such as Parkinson's or Alzheimer's…
- Conditions
- PARKINSON DISEASE (Disorder), Parkinson, Parkinson Disease, Parkinson s Disease
- Trial name
- Met-Pro (NCT07786116)
- Testing
- Probiotic Supplementation with L. reuteri
- Where
- United Kingdom
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Attention-Deficit / Hyperactivity Disorder
A Long-Term Study on Safety of JNS001 in Adults With Attention-Deficit Hyperactivity Disorder
The main purpose of this study is to evaluate long-term safety and tolerability of JNS001 at 18 to 72 mg per day in adults with Attention-Deficit/Hyperactivity Disorder (ADHD).
- Trial name
- NCT01357993
- Testing
- JNS001
- Where
- 29 sites in Japan
- Volunteers
- 253 people
- Sponsor
- Janssen Pharmaceutical K.K.
ADHD, Attention Deficit Hyperactivity Disorder
Technology-Enhanced Executive Functioning Intervention for ADHD
This study develops and refines an online platform that will support clinician-directed behavioral and organizational skills intervention for adolescents with Attention-Deficit/Hyperactivity Disorder (ADHD) with input guided from…
- Conditions
- ADHD, Attention Deficit Hyperactivity Disorder, Attention Deficit Disorder, ADD
- Trial name
- NCT04729439
- Testing
- Homework Organization and Planning Skills (HOPS) Intervention, Digital Health Application (Online Platform) for Encouraging Skills Practice
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's National Research Institute
Attention Deficit Hyperactivity Disorder (ADHD)
Efficacy and Safety of Lisdexamfetamine Dimesylate (LDX) in Adolescents With Attention-Deficit/Hyperactivity Disorder (ADHD)
The study will evaluate the efficacy of LDX treatment group compared to placebo on the change from Baseline ADHD-RS-IV score at endpoint.
- Trial name
- NCT00735371
- Testing
- LDX 30 mg, LDX 50 mg, LDX 70 mg
- Where
- 45 sites in United States
- Volunteers
- 314 people
- Sponsor
- Shire
Attention-Deficit Hyperactivity Disorder
Efficacy of Trigeminal Nerve Stimulation for ADHD
This study is a large multisite randomized clinical trial to asses the efficacy of external trigeminal nerve stimulation (TNS), a novel, minimal risk, non-invasive neuromodulation treatment, for ADHD in children ages 7-12 years…
- Trial name
- NCT05374187
- Testing
- Active eTNS
- Where
- 2 sites in United States
- Volunteers
- 218 people
- Sponsor
- University of California, Los Angeles
Attention Deficit Disorder With Hyperactivity, Executive Function Disorder
Neurofeedback-Based Digital Therapeutics for the Diagnosis and Treatment of ADHD in Children.
A multi-center, randomized controlled trial is being conducted to investigate the efficacy of a novel digital therapeutics (DTx) program that utilizes a cross-training approach between neurofeedback training and executive…
- Trial name
- ADHD (NCT06369714)
- Testing
- Concerta, Digital therapeutics
- Where
- 2 sites in China
- Volunteers
- 210 people
- Sponsor
- Lei Lei, MD
Tardive Dyskinesia, Intellectual Disability
Deutetrabenazine Treatment for Tardive Dyskinesia in Intellectual/Developmental Disabilities
The primary goal of this study is to investigate the efficacy of deutetrabenazine treatment of TD in this previously untreated patient population.
- Conditions
- Tardive Dyskinesia, Intellectual Disability, Developmental Disabilities
- Trial name
- TD-AIDD (NCT06997198)
- Testing
- Deutetrabenazine Oral Capsule
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University Hospitals Cleveland Medical Center
Attention Deficit Hyperactivity Disorder
Omega-3 Supplementation and Attention-deficit-hyperactivity Disorder (ADHD)
It is assumed that only 1/5 of children diagnosed with attention-deficit-hyperactivity disorder (ADHD) are treated. New treatment modalities are urgently needed.
- Trial name
- NCT00874536
- Testing
- omega-3 fatty acid alpha-linolenic acid (ALA)
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Hadassah Medical Organization
ADHD, Probiotics
Effect of Probiotics on ADHD
Attention-Deficit/Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder. Gut microbiome dysbiosis may be associated with the pathophysiology of ADHD.
- Conditions
- ADHD, Probiotics, Gut Microbiota, Psychiatry
- Trial name
- NCT04958460
- Testing
- BF688
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Wang Liang-Jen
Attention Deficit Hyperactivity Disorder, Borderline Personality Disorder
Performance and FMRI BOLD Signal Changes in Impulsive Patients
This study is a preceding study conducted to validate the methodology for assessing impulsivity by tasks and task-based fMRI measurements in patients with Attention Deficit Hyperactivity Disorder (ADHD) or Borderline Personality…
- Trial name
- NCT06491160
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Simone Grimm
Attention Deficit Hyperactivity Disorder
Training Attentional Awareness and Control in ADHD
The purpose of this study is to evaluate the effects of different types of cognitive training on attention in adults with Attention Deficit Hyperactivity Disorder (ADHD) using mobile software on personal mobile devices.
- Trial name
- SAC-I (NCT02489279)
- Testing
- Sustained Attention Control (SAC) Method, Scrabble
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Think Now Incorporated
Bipolar Disorder, Mood Swing
Seeing the Light: Early Intervention in People at Risk for Bipolar Disorder
In the current study, the feasibility, acceptability and effectivity of a new add-on early intervention program for individuals at risk for the development of bipolar disorder is evaluated.
- Conditions
- Bipolar Disorder, Mood Swing, Prodromal Symptoms
- Trial name
- NCT06282250
- Testing
- Bright light therapy + Psycho-education + Imagery focused Cognitive Therapy, Blue-light blocking glasses + Psycho-education + Imagery focused Cognitive Therapy, Psycho-education + Imagery focused Cognitive Therapy
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Geestelijke Gezondheidszorg Eindhoven (GGzE)
ADHD, PMS
Prevalence of Lidocaine Ineffectiveness in Adults With and Without ADHD
This work will assess the prevalence in the general population of the ineffectiveness of the anesthetic Lidocaine compared to males with ADHD and females with ADHD with or without PMS.
- Trial name
- NCT03676725
- Testing
- Lidocaine gel
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- PhenoSolve, LLC
Intellectual Disability, Fragile X Syndrome
Sensitivity of the NIH Toolbox to Stimulant Treatment in Intellectual Disabilities
This study is a randomized, double-blind, placebo-controlled, crossover trial of extended-release liquid methylphenidate (XRMPH) to evaluate the sensitivity of the NIH Toolbox Cognition Battery (NIHTB-CB) to changes in cognition…
- Conditions
- Intellectual Disability, Fragile X Syndrome, Down Syndrome, Attention Deficit Hyperactivity Disorder
- Trial name
- NCT05301361
- Testing
- Methylphenidate Oral Solution
- Where
- 3 sites in United States
- Volunteers
- 68 people
- Sponsor
- University of California, Davis
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