Clinical trials: Ligament Tear Knee
Anterior Cruciate Ligament Rupture
Arthroscopic ACL Reconstruction: Quadriceps Tendon vs Hamstring Tendon Autograft - A Prospective RCT
A prospective randomized controlled trial comparing functional outcomes of arthroscopic anterior cruciate ligament reconstruction using quadriceps tendon autograft versus hamstring tendon autograft at SMS Medical College, Jaipur.
- Trial name
- NCT07470944
- Testing
- Arthroscopic ACL Reconstruction
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Sawai Mansingh Medical College
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Extended Post-Operative Oral Tranexamic Acid Dosing After ACL Reconstruction
The goal of this clinical trial is to learn whether taking oral tranexamic acid (TXA) for one week after anterior cruciate ligament (ACL) reconstruction improves recovery in adolescents and young adults aged 14 to 25 years.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Pain, Postoperative
- Trial name
- NCT07880743
- Testing
- Tranexamic Acid
- Where
- 6 sites in United States
- Volunteers
- 100 people
- Sponsor
- Dave Bernholt
Anterior Cruciate Ligament (ACL) Tear
Bone-Patellar Tendon-Bone Versus Quadriceps Tendon Autograft for Anterior Cruciate Ligament Reconstruction: A Non-Inferiority Trial Regarding Anterior Knee Pain
This prospective, randomized, single-center, non-inferiority clinical trial will compare anterior knee pain (AKP) after primary anterior cruciate ligament (ACL) reconstruction using either a bone-patellar tendon-bone autograft…
- Trial name
- BTB vs QT (NCT07846709)
- Testing
- Bone-Patellar Tendon-Bone Autograft ACL Reconstruction, Quadriceps Tendon Autograft ACL Reconstruction
- Volunteers
- 150 people
- Sponsor
- Hospital del Mar
Anterior Cruciate Ligament Tear
Comparison of Early Versus Delay Reconstruction in Anterior Cruciate Ligament Tearing
The purpose of this study is to determine which surgical method is better for anterior cruciate ligament teas in outcomes.
- Trial name
- NCT01580722
- Testing
- early reconstruction, delay reconstruction
- Where
- Iran
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Anterior Cruciate Ligament Rupture
The Effects of Hormonal Contraceptives on Incidence of ACL Injury Within Menstrual Cycle Phases
The aim of this study is to investigate how hormonal contraceptives affect ACL rupture incidence within menstrual cycle phases. It is thought hormones such as estrogen and progesterone (which fluctuate throughout the normal…
- Trial name
- NCT04986267
- Testing
- ACL Rupture
- Where
- Australia
- Volunteers
- 98 people
- Sponsor
- University of South Australia
Hand Injuries, Wrist Injuries
Hand Ligament Reconstructions With Knee Collateral Ligament Allografts
The purpose of this study is to review the clinical outcomes following hand ligament reconstruction surgery using allograft (cadaveric) knee collateral ligaments.
- Conditions
- Hand Injuries, Wrist Injuries, Ligament Injury, Ligament Rupture
- Trial name
- NCT05060900
- Testing
- Ligament Reconstruction with Allograft Ligament
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Cedars-Sinai Medical Center
Knee Injury
Study to Prevent Cartilage Damage Following Acute Knee Injury.
Individuals who have had a severe knee injury have an increased risk of developing arthritis of the knee and at a much earlier age than would otherwise be expected.
- Trial name
- NCT00332254
- Testing
- Anakinra
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Duke University
Orthopedic, Rupture
Clinical Screening of Acute Ruptures of the Anterior Cruciate Ligament of the Knee
This study develops the construction and validation of a reliable functional screening score in LCA ruptures in the immediate post-traumatic period.
- Trial name
- ACL-TS (NCT03113734)
- Testing
- Construction and validation of a functional score
- Where
- France
- Volunteers
- 355 people
- Sponsor
- French Arthroscopic Society
Anterior Cruciate Ligament Rupture, Acute Pain
Femoral Triangle + IPACK Blocks for ACL Reconstruction Analgesia
An adequate balance between analgesia and motor function is an essential requirement to facilitate functional recovery and early discharge after anterior cruciate ligament (ACL) reconstruction surgery. Proximal nerve blocks (i.e.
- Conditions
- Anterior Cruciate Ligament Rupture, Acute Pain, Pain, Postoperative, Knee Injuries
- Trial name
- NCT05068063
- Testing
- Bupivacaine Injection, normal Saline
- Where
- 2 sites in Chile
- Volunteers
- 48 people
- Sponsor
- University of Chile
Ligament Injury, Ligament; Laxity
Methylsulfonylmethane on Knee Laxity
The proposed research will focus on determining the effect of methylsulfonylmethane (MSM) on knee laxity changes through the menstrual cycle in young active females.
- Conditions
- Ligament Injury, Ligament; Laxity, Tendon Rupture, Tendon Injuries
- Trial name
- NCT03747198
- Testing
- methylsulfonylmethane
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Dislocated Patella, Torn Medial Patellofemoral Ligament
Repair of Medial Patellofemoral Ligament Compared to Conservative Treatment for First Time Patella Dislocation
Background: The forces involved in a patella dislocation event can cause significant collateral damage involving the articular cartilage of the patella femoral joint.
- Trial name
- NCT02185001
- Testing
- Direct Medial Patellofemoral Ligament (MPFL) Repair, Physical therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Orthopedic Specialty Institute
Total Knee Arthroplasty, Anterior Cruciate Ligament Reconstruction
Impact of Crutch Type on Gait and Functional Outcomes Post-knee Surgery
Study withdrawn
- Trial name
- NCT04258917
- Testing
- Study withdrawn
- Sponsor
- University of Calgary
Anterior Cruciate Ligament Rupture
Obtain Safety and Effectiveness of CT-ACL001, a Regenerative Ligament Using Biological Tissue, in ACLR
A randomized, multicenter study comparing the safety and efficacy of CT-ACL001, a regenerative ligament, with standard treatment in anterior cruciate ligament reconstruction
- Trial name
- NCT07129694
- Testing
- Anterior cruciate ligament reconstruction
- Where
- 6 sites in Japan
- Volunteers
- 64 people
- Sponsor
- CoreTissue BioEngineering Inc.
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Physical Activity, Knee Joint Loading and Joint Health
The purpose of this study is to investigate the association between time spent in moderate to vigorous physical activity and markers of cartilage metabolism in the years following anterior cruciate ligament reconstruction.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear, Post-traumatic Osteoarthritis
- Trial name
- NCT05306054
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Bath
ACL - Anterior Cruciate Ligament Rupture
Optimizing Graft Selection for ACL Reconstruction
Purpose: To investigate the differences between the three most common methods for reconstruction of the anterior cruciate ligament (ACL), to support the development of the best method for the individual patient.
- Trial name
- GRASE-ACL (NCT05342441)
- Testing
- QT graft, ST/Gr graft, BPTB graft
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Hvidovre University Hospital
Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament (ACL) Tear
Active Noise-Cancelling Headphones With Closed-Loop Communication During Arthroscopic ACL Reconstruction
Operating room noise may interfere with communication, concentration, and surgical workflow. Active noise-cancelling (ANC) headphones can reduce background auditory distractions; however, their potential benefit during surgery…
- Conditions
- Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Injury
- Trial name
- ANC-ACL-2026 (NCT07589582)
- Testing
- Active Noise-Cancelling Headphones With Closed-Loop Communication, Standard Operating Room Communication
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Aseptic Loosening, Infection
Maxx Orthopedics' PCK Revision TKA Study of Component Survivorship
The objectives of this clinical investigation are to evaluate the safety and performance of the Freedom Total Knee® PCK System.
- Conditions
- Aseptic Loosening, Infection, Bone Loss, MCL - Medial Collateral Ligament Rupture of the Knee
- Trial name
- NCT03312088
- Testing
- Freedom Knee PCK Components
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Maxx Orthopedics Inc
Anterior Cruciate Ligament Rupture
Safety and Efficacy of the Knee-T-nol Anterior Cruciate Ligament (ACL) Prosthesis
The study is designed to evaluate the safety and efficacy of implanting the Tavor ACL prosthesis in patients with a ruptured ACL by improvement of healing kinetics as well as major adverse treatment events (AEs).
- Trial name
- NCT01450332
- Testing
- Knee-T-Nol
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Tavor Ltd.
Anterior Cruciate Ligament Reconstruction, Anterior Cruciate Ligament Injuries
Supporting Athletes' Return to Sports After ACL Reconstruction: A Study of a Psychological Readiness Program
The goal of this clinical trial is to learn whether an online mental and emotional support program called ACL Unbroken can help people recovering from ACL reconstruction surgery feel more confident and ready to return to sports…
- Conditions
- Anterior Cruciate Ligament Reconstruction, Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Tear
- Trial name
- UnbrokenACL (NCT07851298)
- Testing
- Unbroken Comeback
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Inova Health Care Services
Rupture of Anterior Cruciate Ligament
Comparison of the Functional Outcome of Site Peroneus Longus Graft Donors With and Without Distal Stump Suturing of Peroneus Tendon Brevis on ACL Reconstruction Case in Cipto Mangunkusumo Hospital in Jakarta With 24 Patient as Subject Who Will Divide Into 2 Group.
Injury of the Anterior Cruciate Ligament (ACL) is one of the most common sports injuries. The incidence rate reaches 68.6 cases per 100,000 people per year.
- Trial name
- NCT04431063
- Testing
- Distal Stump Suturing
- Where
- Indonesia
- Volunteers
- 24 people
- Sponsor
- Universitas Indonesia