Clinical trials: Ligament Tear Knee
ACL, ACL Injury
Acupuncture ACL (Anterior Cruciate Ligament)
Acupuncture research in regards to PONV has been fairly well established, however, studies about perioperative pain control and acupuncture are a little more murky.
- Conditions
- ACL, ACL Injury, Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
- Trial name
- NCT03711734
- Testing
- Acupuncture + Standard of Care
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
ACL Tear
Comparison Effectiveness Analysis Between ACL Reconstruction and Rehabilitation in Peripheral and Main Capital in Indonesia
The study was a prospective observational analysis of cases with complete ACL tears. A study was conducted between February 2021 to December 2024.
- Trial name
- Cetjap-Asin (NCT04748328)
- Testing
- ACL Reconstruction surgery and Rehabilitation Treatment
- Where
- Indonesia
- Volunteers
- 100 people
- Sponsor
- Universitas Riau
Anterior Cruciate Ligament Rupture
Tolerance, Efficacy, revAlidation, Myostim
Evaluation of efficacy and tolerance of a food supplement (MYOSTIM®) versus a placebo in postoperative revalidation of patients after reconstructive surgery of anterior cruciate ligament.
- Trial name
- NCT04684771
- Testing
- MYOSTIM®
- Where
- 2 sites in Belgium
- Volunteers
- 35 people
- Sponsor
- Alternativa International S.A
Anterior Cruciate Ligament Rupture
Number One Overall Graft Pick? Hamstring vs Bone-Patellar-Tendon-Bone vs Quadriceps Tendon
The main purpose of this study is to determine if there is a difference in graft re-injury/failure rates between participants that have had an ACL reconstruction with a STG, BPTB or QT autograft.
- Trial name
- NCT03671421
- Testing
- ACL reconstruction - graft choice
- Where
- Canada
- Volunteers
- 297 people
- Sponsor
- Panam Clinic
Rupture of Anterior Cruciate Ligament
A Pilot Study to Investigate Biomarkers in Anterior Cruciate Ligament (ACL) Patients and Healthy Controls
Incident rates of ACL rupture are greatest in 16-39 year olds at almost 1 in 1,000. Performance Based Investigations (PBIs) can be used to evaluate and select correct approaches to patient treatment, and biochemical…
- Trial name
- NCT02300012
- Testing
- Surgeons knowledge of pre-operative PBIs
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- United Lincolnshire Hospitals NHS Trust
ACL Tear
3D Reconstruction of the Knee Based on MRI
ACL tear is a pathology of the knee quite common in athletes mainly caused by a twisting movement. The diagnosis of ACL tear can be confirmed by MRI (magnetic resonance imaging).
- Trial name
- IMAGENOU3D (NCT05912777)
- Testing
- Scanner
- Where
- France
- Volunteers
- 58 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
ACL - Anterior Cruciate Ligament Rupture
Prospective Evaluation of Osseous Integration in ACL Reconstruction Comparing Tightrope vs Interference Screw Fixation
The purpose of our study was to compare osseous integration of the bone block in Achilles tendon allograft ACL reconstruction using a cortical button versus biocomposite interference screw fixation.
- Trial name
- NCT03841500
- Testing
- Biocomposite intereference screw femoral tunnel fixation, Endobutton (Tightrope) femoral tunnel fixation
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Kelsey-Seybold Clinic
Anterior Cruciate Ligament Tear
Prognosis Analysis of Three Surgical Techniques for Arthroscopic Anterior Cruciate Ligament Reconstruction
This study hypothesizes that the tunnel positioning and drilling direction in two single-bundle reconstruction techniques (Anatomical Single-Bundle Reconstruction, ASBR, and Central Axial Single-Bundle Reconstruction, CASBR)…
- Trial name
- NCT06891430
- Testing
- Procedure: Anatomical Single-Bundle ACL Reconstruction, Procedure: Central Axial Single-Bundle ACL Reconstruction, Procedure: Double-Bundle ACL Reconstruction
- Volunteers
- 180 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Anterior Cruciate Ligament Tear
Comparison of Two ACL Reconstruction Techniques: All-inside Versus Complete Tibial Tunnel Technique
This study intends to perform an all-inside and complete tibial tunnel ACL reconstruction technique in 80 patients, and compare the clinical and radiological outcomes of the two surgical procedures through follow-up.
- Trial name
- NCT05574946
- Testing
- Anterior Cruciate Ligament Reconstruction
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 71 people
- Sponsor
- Samsun University
Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction Rehabilitation
Analysis Of Knee Joint Of Patients With Anterior Cruciate Ligament Injury Undergoing Physiotherapy After Two Different Surgical Techniques: A Randomized Clinical Trial.
The objetive is compare knee joint stability, functional capacity, postural control, activation, and muscle strength of patients undergoing conventional Anterior Cruciate Ligament Reconstruction or the conventional Anterior…
- Trial name
- NCT06809920
- Testing
- Group 1 ACL reconstruction with quadruple flexor tendons and conventional physiotherapy, Group 2 ACL reconstruction with quadruple flexor tendons + ALL reconstruction
- Where
- 2 sites in Brazil
- Volunteers
- 26 people
- Sponsor
- Universidade Estadual de Londrina
Rupture of Anterior Cruciate Ligament, Muscle Degeneration
Can Targeted Exercise Improve Knee Strength Following ACLR (RATE)
Anterior cruciate ligament reconstruction (ACLR) is high volume surgery, carried out in about 2800 patients annually in Denmark per year.
- Conditions
- Rupture of Anterior Cruciate Ligament, Muscle Degeneration, Gait, Unsteady
- Trial name
- RATE (NCT02939677)
- Testing
- Targeted exercise
- Where
- Denmark
- Volunteers
- 51 people
- Sponsor
- University of Southern Denmark
Rupture of Anterior Cruciate Ligament
Evaluation of rGH Therapy to Prevent Muscle Atrophy in Patients With ACL Tears
Anterior cruciate ligament (ACL) tears are among the most frequent traumatic knee injuries that occur in physically active individuals.
- Trial name
- NCT02420353
- Testing
- Somatropin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan
Knee Osteoarthritis, Knee Injuries
Dronabinol After Arthroscopic Surgery
The purpose of the proposed study is to evaluate the efficacy of dronabinol for postoperative pain after arthroscopic surgery of the knee.
- Conditions
- Knee Osteoarthritis, Knee Injuries, Meniscus Tear, Synovitis of Knee
- Trial name
- NCT05335252
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Northwestern University
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
The BEAR III Trial for Bridge-Enhanced ACL (Anterior Cruciate Ligament) Restoration
Bridge-Enhanced ACL Restoration (BEAR) is a new procedure being developed to treat patients with ACL injuries. In the BEAR procedure, an implant is placed between the torn ends of the ACL and the patient's own blood is added to…
- Trial name
- NCT03348995
- Testing
- Bridge-Enhanced ACL Restoration (BEAR)
- Where
- 11 sites in United States
- Volunteers
- 250 people
- Sponsor
- Miach Orthopaedics
ACL Reconstruction
Efficacy and Tolerability of a Nutritional Supplement, Plactive Progen, in ACL Reconstruction
This was a prospective, multicenter, randomized, open-label, phase IV trial to compare the efficacy of supplementation with plasma proteins, hydrolyzed collagen (CH), a complex of HA-CS (HC-15), and vitamin C combined with a…
- Trial name
- NCT03355651
- Testing
- PROGEN
- Volunteers
- 80 people
- Sponsor
- OPKO Health, Inc.
Anterior Cruciate Ligament Rupture
Single Bundle Anterior Cruciate Ligament Reconstruction in Active Young Men
The clinical outcomes of anterior cruciate ligament reconstruction using free tendon Achilles allograft are comparable to those using Achilles allograft with bone block on its end.
- Trial name
- NCT01533025
- Testing
- anterior cruciate ligament reconstruction
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- National Police Hospital
Ligament; Laxity, Knee, Anterior Cruciate Ligament Injury
Treatment of Anterior Ligament Rupture With Internal Brace Repair - A Prospective Randomised Controlled Study.
The purpose of this study is to determine whether anterior cruciate ligament injury in patients wishing to return to sports activities may be treated with repair supplemented with internal brace compared with a standard operation…
- Trial name
- NCT03800225
- Testing
- Repair
- Where
- Denmark
- Volunteers
- 4 people
- Sponsor
- Aarhus University Hospital
ACL Tears
BioBrace® Augmentation in Anterior Cruciate Ligament Reconstruction Procedures
This research study will evaluate mid-term clinical safety and performance outcomes of the BioBrace® Reinforced Implant when used to augment a tissue graft during anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NCT06948591
- Testing
- Anterior cruciate ligament reconstruction with BioBrace® augmentation, Arthroscopic anterior cruciate ligament reconstruction
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- CONMED Corporation
Anterior Cruciate Ligament Injuries
How to Best Treat Anterior Cruciate Ligament Injuries
The project is a pragmatic registry-based RCT aiming to investigate ACL injury treatment. Study results will help fill knowledge gaps, facilitate shared decision making and strengthen patient treatment.
- Trial name
- NCT04770233
- Testing
- Early ACL reconstruction, Active rehabilitation
- Where
- 2 sites in Norway
- Volunteers
- 328 people
- Sponsor
- University Hospital, Akershus
Anterior Cruciate Ligament Tear
Anterior Cruciate Ligament (ACL) Reconstruction: Single Bundle Versus Double Bundle
ACL tear is a common injury among athletes. The recommended treatment includes reconstruction of the ligament. The common reconstruction technique is single bundle reconstruction.
- Trial name
- NCT01025895
- Testing
- acl reconstruction - double bundle technique, acle reconstruction - single bundle technique
- Volunteers
- 60 people
- Sponsor
- Assaf-Harofeh Medical Center