Clinical trials: Light
Arthroplasty, Replacement, Hip
Effects of Photobiomodulation Therapy (PBMT) in Total Hip Arthroplasty
Osteoarthritis (OA), a chronic degenerative muscle disease characterized by cartilage wear, causes progressive joint deformity and loss of function leading to the indication of total hip arthroplasty (THA), when conservative…
- Trial name
- NCT02970890
- Testing
- Portable Pain Away™
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Adriane Aver Vanin
Vascular Access
Comparison of Different Techniques on First Attempt Success in Difficult Vascular Access Patients
The aim of this study is to investigate whether there is any difference between the use of standard techniques, ultrasonography and infra-red light for the success of the first attempt in difficult peripheral vascular access…
- Trial name
- NCT04821362
- Testing
- Ultrasound group, Near Infrared Device Group
- Where
- Turkey (Türkiye)
- Volunteers
- 270 people
- Sponsor
- Ege University
Vitamin D Deficiency, Vitamin D Insufficiency
Evaluating the Effect of SOLIUS UV Light Source in Improving Vitamin D Status
The aim of this study is to evaluate the safety and effectiveness of the SOLIUS System in improving serum levels of 25-hydroxyvitamin D in vitamin D deficient/ insufficient adults of various skin types.
- Trial name
- NCT04780776
- Testing
- UVB treatment
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Boston University
Actinic Keratoses
Efficacy And Safety Of Illumination Dose Reduction In Red Light Photodynamic Therapy For Actinic Keratoses
The goal of this clinical trial is to compare the tolerance and efficacy of conventional photodynamic therapy (PDT) with red light versus PDT with red light at half dose of illumination, as well as the changes produced by both…
- Trial name
- NCT06545396
- Testing
- Half-dose illumination protocol, Full-dose illumination protocol
- Volunteers
- 20 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Light Chain Deposition Disease, Primary Systemic Amyloidosis
First-line Pomalidomide, Bortezomib, and Dexamethasone For AL Amyloidosis or LCDD
This phase I trial studies the side effects and best dose of pomalidomide and bortezomib when given together with dexamethasone in treating patients with amyloid light-chain amyloidosis or light chain deposition disease.
- Trial name
- NCT01728259
- Testing
- pomalidomide, bortezomib, dexamethasone
- Where
- 5 sites in United States, Canada
- Volunteers
- 18 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Healthy
Study To Assess The Effect Of PF-04531083 On Heat Pain In Healthy Volunteers With Ultraviolet Light Sensitized Skin
PF-04531083 has been shown to reduce the amount of heat pain experienced by rats with skin that has been sensitized to heat by ultraviolet light. This study is designed to see if this is also true in man.
- Trial name
- NCT01127906
- Testing
- PF-04531083 100mg, PF-04531083 2000mg, Oxycodone 20mg
- Where
- Belgium
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pfizer
Multiple Myeloma and Plasma Cell Neoplasm
Lenalidomide, Cyclophosphamide, and Dexamethasone in Treating Patients With Primary Systemic Amyloidosis
RATIONALE: Biological therapies, such as lenalidomide, may stimulate the immune system in different ways and stop plasma cells from growing.
- Trial name
- NCT00564889
- Testing
- cyclophosphamide, dexamethasone, lenalidomide
- Where
- 3 sites in United States
- Volunteers
- 35 people
- Sponsor
- Mayo Clinic
Skin Aging
Evaluation of the Efficacy and Tolerance of a Light Therapy Mask on Mild to Moderate Brown Spots and Moderate to Severe Facial Wrinkles
This research study will test how well a light therapy mask works for women with mild to moderate hyperpigmentation (brown spots) and moderate to severe facial wrinkles, as compared to a "sham" or inactive investigational light…
- Trial name
- NCT03312543
- Testing
- Active Mask
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
AL Amyloidosis, Amyloidosis
Quality of Life (QOL) Registry for Patients With AL Amyloidosis
This is an online registry to document the psychometric properties of SF-36v2 among patients with AL Amyloidosis, to document patients' burden of disease, to better understand the patient's experience and to follow quality of…
- Trial name
- NCT02574676
- Testing
- non-interventional
- Where
- United States
- Volunteers
- 343 people
- Sponsor
- Prothena Biosciences Ltd.
Infertility
Improving IVF Embryo Quality Grading Using Polarized Light
Selecting one or two IVF embryos with the highest potential to implant is extremely important for the success of the treatment- obtaining pregnancies and avoiding multi-fetal gestations.
- Trial name
- NCT01601249
- Testing
- Embryo selection based on polscope grading or morphology
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Vitamin D Deficiency
Impact of Work Environment Absent of Natural Light on Vitamin D Levels
Three types of workers exposed to different levels of natural sunlight will be tested for Vitamin D blood level, PTH, Ca, P, albumin and alkaline phosphatase.
- Trial name
- NCT01385085
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Delayed Sleep Phase Disorder
Light Flashes to Treat Delayed Sleep Phase Disorder (DSPD)
Delayed Sleep Phase Disorder (DSPD) is a sleep disruption that commonly occurs in teens and manifests as a difficulty in waking up in the morning, going to sleep early enough at night, and daytime disturbances such as depression…
- Trial name
- NCT01406691
- Testing
- Flashes
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stanford University
Ultraviolet Rays
Proof-of-concept Study on Disinfection and Healing Acceleration Capabilities of 222nm Wave Length Narrow Band Ultraviolet Lighting Device
The threat of MRSA and multi-drug resistant pathogens have been growing in recent years. A new means of countering the infectious threat is required and one such modality is the use of UV light for disinfection.
- Trial name
- NCT03526068
- Testing
- SafeZoneUVC
- Where
- Singapore
- Volunteers
- 16 people
- Sponsor
- National University Hospital, Singapore
Delirium
Prevention of Delirium With Light in the Intensive Care Unit
The purpose of this multicenter randomised controlled trial is to investigate if circadian light at the patients bedside (using Philips HealWell system, CE marked)significantly reduces prevalence of delirium in mechanically…
- Trial name
- PreDeLight-ICU (NCT01727375)
- Testing
- Circadian light
- Where
- Germany
- Sponsor
- Charite University, Berlin, Germany
Hirsutism
Facial Hair Reduction Using Intense Pulsed Light (IPL) & Alexandrite Laser
The purpose of this study is to compare the efficacy of the IPL system 650advance handpiece with the alexandrite laser for the purposes of female facial hair reduction
- Trial name
- NCT01461694
- Testing
- Intense Pulsed Light (IPL), Alexandrite Laser
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Psoriasis Vulgaris
Investigation of Antipsoriatic Effects of UVB-induced Synthesis of 1alpha, 25-Dihydroxyvitamin D3 (1alpha, 25(OH)2D3, Calcitriol)in Keratinocytes of Psoriatic Skin, Using Cytochrom-P(CYP)Inhibitor Ketokonazol
Exploration of antipsoriatic effects of UVB-therapy +/- CYP-inhibitor Ketokonazol on affected psoriatic skin
- Trial name
- VITAKET (NCT00678756)
- Testing
- Ketokonazol 2% cream, UVB-radiation 311nm
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- Technische Universität Dresden
Hyperbilirubinemia, Neonatal
Effectiveness of Phototherapy With and Without Probiotics
Raised serum bilirubin levels can cause kernicterus and premature infants are at increased risk due to metabolic immaturity. The standard treatment for neonatal jaundice is phototherapy but probiotics along with it can reduce the…
- Trial name
- NCT06173856
- Testing
- LED phototherapy
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- Fatima Jinnah Medical University
Alzheimer's Disease
Effect of Therapeutic Light on Sleep, Circadian Rhythm, and Global Function in Women With Alzheimer's
Determine effect and duration of effect of timed therapeutic light compared to control light on parameters of circadian rhythmicity, physiologic plasticity, sleep, and global function in women with Alzheimer's Disease.
- Trial name
- NCT02502045
- Testing
- Morning Simulated Sunlight, Non-therapeutic Red Light
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Yale University
Ocular Conditions Resulting in Visual Impairment
Low Vision Patients' Preference for Colored Filters and Illumination for Near Reading Determined by the LuxIQ/2
The effect of tinted filters and illumination on the visual performance of patients with low vision (i.e., individuals with reduced vision that is uncorrectable with glasses, surgery or treatments) has been a topic of research…
- Trial name
- NCT03192722
- Testing
- Colored near reading glasses, Lighting as determined by LuxIQ/2 or OttLite Cobra
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Nova Southeastern University
Migraine Headache, Sleep
Light Exposure, Migraine Outcomes, and Sleep Quality
The purpose of this study is to examine the relationship between daily light exposure patterns, sleep quality, and migraine characteristics in adults with migraine, with and without photophobia, across an 8-week study period.
- Conditions
- Migraine Headache, Sleep, Photophobia
- Trial name
- NCT07476053
- Testing
- Ambient Lighting Condition
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Arizona State University