Clinical trials: Light Therapy
Chronic Myeloproliferative Disorders, Leukemia
506U78 in Treating Patients With Hematologic Cancer and Kidney or Liver Impairment
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of 506U78 in treating patients who have hematologic cancer…
- Conditions
- Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00004239
- Testing
- Compound 506U78
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Hair Removal
Hair Removal: Intense Pulsed Light Versus Diode Laser
The goal of this clinical trial is to compare the effectiveness of two hair removal techniques: Intense Pulsed Light (IPL) and Diode Laser in woman underarm. .
- Trial name
- NCT06179186
- Testing
- Intense Pulsed Light, Diode Laser
- Where
- 2 sites in Brazil
- Volunteers
- 48 people
- Sponsor
- University of Nove de Julho
High-Grade Glioma (WHO III-IV), Cerebral Vascular Conditions Requiring Surgical Intervention
Evaluation of Image Quality and Safety of the MyVeo Surgical Visualization Headset During Standard Neurosurgical and Reconstructive Procedures Using Compatible Microscopes.
This study looks at how well the MyVeo surgical visualization headset works during routine surgeries. MyVeo is a wearable device that helps surgeons see the surgical area in high detail, including blood flow and tissue…
- Conditions
- High-Grade Glioma (WHO III-IV), Cerebral Vascular Conditions Requiring Surgical Intervention, Conditions Requiring Plastic and Reconstructive Surgery
- Trial name
- IMED-MYVEO (NCT07164053)
- Testing
- MyVeo is an all-in-one surgical visualization headset used with compatible surgical microscopes and other medical imaging systems in the area of neurosurgery, ENT, spine, plastic and reconstructive su
- Where
- 2 sites in Spain, Switzerland
- Volunteers
- 32 people
- Sponsor
- Leica Microsystems (Schweiz) AG
Multiple Sclerosis
CSF Free Kappa Light Chain for The Diagnosis of Demyelinating Disorders
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) which commonly leads to disability. The current preferred clinical laboratory test for the diagnosis is the detection of oligoclonal bands…
- Trial name
- NCT05347277
- Testing
- Kappa Free Light Chain (K-FLC)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Aga Khan University
Age-related Macular Degeneration, Aging
Functionally Validated Structural Endpoints for Early AMD
Delayed rod-mediated dark adaptation (RMDA), or delayed recovery of vision in a dark environment, is a functional biomarker (i.e., risk factor) for early age-related macular degeneration (AMD).
- Trial name
- ALSTAR2 (NCT04112667)
- Testing
- Normal Macular Health, Early Macular Degeneration, Young Normals
- Where
- United States
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- Cynthia Owsley
Visible Light Exposure on Healthy Back Skin
Photoprotection Efficacy of Different Topical Agents Under Visible Light Exposure
To evaluate the protective effect of seven sunscreens on the pigmentation induced by visible light in comparison to an untreated control zone in healthy volunteers
- Trial name
- NCT06796153
- Testing
- Visible Light Exposure - Treated zones, Visible Light Exposure - Untreated zone
- Where
- Romania
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Raynaud's Phenomenon, Skin Necrosis
Prognostic Influence of Light Rheography Measurement of Patients With Secondary Raynaud Syndrome With Ulcers on Hands
The purpose of this study is to evaluate the prognostic influence of light rheography measurement at the fingertips from subjects with secundary Raynaud syndrome.
- Trial name
- Anti-Vasospasm (NCT01378845)
- Testing
- Tracleer, Prostavasin
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Christoph Hehrlein
Vitiligo
Tyrosine Vs Tacrolimus With NB-UVB in Vitiligo
The goal of this clinical trial is to learn if adding topical tacrolimus or topical tyrosine to narrowband UVB phototherapy works to treat vitiligo in adults. It will also learn about the safety of both combinations.
- Trial name
- NCT07532330
- Testing
- Narrowband UVB Phototherapy, Topical Tacrolimus 0.1% ointment, Topical Tyrosine 2% cream
- Where
- Egypt
- Volunteers
- 67 people
- Sponsor
- Minia University
Breast Cancer, Radio Dermatitis
Photobiomodulation in Radiodermatitis in People With Breast Cancer
Most breast cancer patients undergoing radiotherapy develop radiodermatitis, making it one of the most prevalent adverse events during cancer treatment.
- Trial name
- NCT06990165
- Testing
- Photobiomodulation
- Where
- 2 sites in Brazil
- Volunteers
- 148 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Gynecologic Cancer Survivors, Sleep Quality
Effects of Bright Light on Sleep Quality, Fatigue , and Mood Symptoms in Survivors With Gynecologic Cancer
Objective: This study aimed to examine the efficacy of light therapy in improving sleep quality, reducing fatigue, and alleviating emotional symptoms among patients diagnosed with gynecologic cancer.
- Conditions
- Gynecologic Cancer Survivors, Sleep Quality, Fatigue, Mood Symptoms
- Trial name
- NCT07132580
- Testing
- Re-Timer® light therapy glasses, Usual Care
- Where
- Taiwan
- Volunteers
- 94 people
- Sponsor
- Chang Gung Memorial Hospital
Relapse Remitting Multiple Sclerosis
Early Versus Delayed Start of Ocrevus Zunovo for Relapsing Multiple Sclerosis
This study will compare starting Ocrevus Zunovo soon after an active episode of relapsing multiple sclerosis (MS) with starting it later.
- Trial name
- STAT (NCT07878923)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Oklahoma Medical Research Foundation
Hypotension, Spinal Anesthesia
Pupillary Light Reflex to Predict Post-Spinal Hypotension in Elective Cesarean Delivery
This prospective observational cohort study investigates whether pre-anesthetic pupillary light reflex (PLR) parameters can predict the risk of hypotension following spinal anesthesia in women undergoing elective cesarean…
- Conditions
- Hypotension, Spinal Anesthesia, Cesarean Delivery
- Trial name
- NCT07678723
- Testing
- Not applicable- observational study
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Treatment of Depressive Symptoms in Cancer Patients
Treatment of Depressive Symptoms in Breast Cancer Patients: Comparison of Cognitive Therapy and Bright Light Therapy
Depressive symptoms are highly frequent among cancer patients. These symptoms significantly impair quality of life (e.g., hopelessness, greater risk of suicidal behaviours) and may even affect patients' prognosis (e.g., through…
- Trial name
- NCT01637103
- Testing
- Cognitive therapy of depression, Bright light therapy
- Where
- Canada
- Volunteers
- 62 people
- Sponsor
- CHU de Quebec-Universite Laval
Effects of Blue-light Blocking Lens on Visual Functions
Effects of Blue-light Blocking Lens on Visual Functions
Working Hypothesis: The blue-light blocking lens has no effect on the contrast sensitivity, accommodative response, color vision, and subjective grading of the quality of life and vision.
- Trial name
- NCT02821403
- Testing
- clear lens with regular coating, regular coating lens with yellow tint, clear lens with blue-light blocking coating
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Androgenetic Alopecia, Hair Loss
Low Level Light Device as a Primary Therapy for Androgenetic Alopecia
The purpose of this research is to study the safety and effectiveness of a light therapy device for human hair growth. This device, called the GENIX, is a type of cold, or non-heat producing light emitting diode (LED) that will…
- Conditions
- Androgenetic Alopecia, Hair Loss, Thinning Hair, Balding
- Trial name
- NCT04558242
- Testing
- Genix
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kiierr International, LLC
Alopecia
"iRestore" Light Therapy Apparatus
Current effective therapies of pattern hiar loss are topical minoxidil and oral finasteride. Finasteride is an inhibitor of type 2 5α-reductase and will cause hypospadias in male infant if taken or touched by pregnant woman.
- Trial name
- NCT03331003
- Testing
- low level light therapy, non-LLLT wavelength group
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders
Pemetrexed Disodium in the Cerebrospinal Fluid of Patients With Leptomeningeal Metastases
RATIONALE: Pemetrexed disodium may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Studying samples of cerebrospinal fluid and blood from patients with cancer in the laboratory may help…
- Conditions
- Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma
- Trial name
- NCT00424242
- Testing
- Pemetrexed
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Northwestern University
Traumatic Brain Injury, Fatigue
Treatment of Post-Traumatic Brain Injury (Post-TBI) Fatigue With Light Therapy
This study aims to evaluate the efficacy of 4 weeks of daily light exposure in reducing Post-Traumatic Brain Injury (TBI) Fatigue immediately post-treatment and at a one-month follow up.
- Trial name
- NCT01725750
- Testing
- Bright White Light (BWL), Dim Red Light (DRL)
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pupil Diameter, Pupil Contraction Rate
The Guiding Significance of Pupil Monitoring in the Perioperative Period
The pupil diameter is affected by both sympathetic and parasympathetic nerves, and its latency and response amplitude mainly reflect the functional status of the parasympathetic nerve.
- Conditions
- Pupil Diameter, Pupil Contraction Rate, Pupil Light Reflection
- Trial name
- NCT04820374
- Testing
- pupil's light and pupil diameter
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Yangzhou University
Migraine, Headache
Narrow Band Green Light and Migraine
Study volunteers are asked to use the Allay Lamp routinely during the 6-week study period. A web based survey is provided when the Lamp is purchased for study volunteers to complete.
- Trial name
- NCT04841083
- Testing
- Allay Lamp
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- Vedanta Research