Clinical trials: Limb Fracture
Bone Fractures, Traditional Chinese Medicine
Therapeutic Effects of Traditional Chinese Medicine in Topical Use on Upper Extremities Fracture
There is no study evaluating the clinical effect of traditional chinese medicine(TCM) in topical use on musculotendinous injury, nor is that investigating the effectiveness on bone fracture healing.
- Conditions
- Bone Fractures, Traditional Chinese Medicine, Chinese Herbal Medicine
- Trial name
- NCT04593849
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- YUAN-CHIEH YEH
Exostosis of Elbow, Upper Extremity Fracture
Virtual Reality Distraction From Procedural Pain in Children
This study explored the feasibility, acceptability and perceived the effectiveness of an Immersive Virtual Reality (IVR) 'game' in the rehabilitation of children with upper limb injuries.
- Conditions
- Exostosis of Elbow, Upper Extremity Fracture, Burn; Arm, Burn Scald
- Trial name
- NCT03998995
- Testing
- Immersive Virtual Reality
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Sheffield Hallam University
Radius Fractures
Comparison 1 Plane-2 Injection and 2 Plane-2 Injection Ultrasound-guided Supraclavicular Brachial Plexus Block
The supraclavicular block can provide effective surgical anesthesia of the forearm and hand. There have been many different approaches to ultrasound-guided supraclavicular brachial plexus block (US-SCBPB) according to the needle…
- Trial name
- US-SCBPB (NCT02533557)
- Testing
- stimuplex insulated needle, lidocaine mixed with epinephrine
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gachon University Gil Medical Center
Open Tibia Fracture, Open Dislocation of Ankle
Accelerated Flap Coverage Versus Standard Timing in the Treatment of Severe Lower Extremity Musculoskeletal Injuries
The goal of this randomized controlled trial is to determine if accelerated flap coverage compared to standard flap coverage timing leads to improved infection-related complications in patients with open fractures and/or…
- Conditions
- Open Tibia Fracture, Open Dislocation of Ankle, Extremity Fracture Lower, Extremity Injuries Lower
- Trial name
- FLAP ATTACK (NCT07828613)
- Testing
- Accelerated Flap Coverage Surgery, Standard of Care Flap Timing
- Where
- 31 sites in United States
- Volunteers
- 356 people
- Sponsor
- Johns Hopkins University
Trauma Injury of Upper Extremity Forearm Multiple, Fracture of Distal End of Radius
Uses of Titanium Nail in Pediatric Fractures
The aim of this study is to investigate the short term functional and radiological outcomes of using double short titanium elastic nails as treatment of pediatric distal radius fractures.
- Trial name
- NCT06276062
- Testing
- Distal radius fracture fixation in pediatrics.
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Sohag University
Infections, Infected Wound
PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation
This is a Phase III clinical randomized control trial to investigate differences between patient with an infected nonunion treated by PO vs. IV antibiotics.
- Conditions
- Infections, Infected Wound, Nonunion of Fracture, Injury Leg
- Trial name
- POvIV2 (NCT05699174)
- Testing
- Standard of Care PO (oral) antibiotics, Standard of Care Intravenous (IV) antibiotics
- Where
- 13 sites in United States
- Volunteers
- 250 people
- Sponsor
- Major Extremity Trauma Research Consortium
Femoral Fractures, Tibial Fractures
Depuy Synthes Lower Extremity Shaft Nail Registry
The purpose of this post-market registry is to monitor the clinical safety and performance (union rates and time to union) of two DePuy Synthes lower extremity shaft nails: RFN-Advanced Retrograde Femoral Nailing System (RFNA)…
- Trial name
- NCT05272631
- Testing
- Retrograde Femoral Nail Advanced, Tibial Nail Advanced
- Where
- 8 sites in United States
- Volunteers
- 241 people
- Sponsor
- DePuy Synthes Products, Inc.
Mallet Fracture, Metacarpal Fracture
Optional Follow-up Visits for Common, Low-risk Arm Fractures
Many common arm fractures have an excellent prognosis with little more than symptomatic treatment. When studying these fractures, investigators find that a substantial number of patients do not attend follow-up appointments.
- Conditions
- Mallet Fracture, Metacarpal Fracture, Metacarpal Neck Fracture, Distal Radius Fracture
- Trial name
- NCT01583556
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Massachusetts General Hospital
Lower Extremity Fractures.
A Study of Postsurgical Pain Control for Lower Extremity Fractures
Postsurgical pain may effectively be treated with a multimodal approach that incorporates the use of local anesthetics. Bupivacaine is a local anesthetic that has been proven to be effective at reducing postsurgical pain.
- Trial name
- NCT02214810
- Testing
- Bupivacaine/Exparel
- Where
- United States
- Sponsor
- Broward Health
Open Fracture Tibia
Evaluate Clinical and Radiological Outcomes After Limb Reconstruction Using Monorail Fixator Over Intramedullary Nailing in Tibial Open Fractures With Bone Loss
Road traffic accidents (RTA) is the most common cause of open fractures of long bones, increase in RTA leading to increase of complex non-unions incidence.
- Trial name
- NCT05296785
- Testing
- intramedullary nail with Limb Reconstruction System
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Tibia Fracture
Splinting Versus Not Splinting of the Distal Lower Extremity After Intramedullary Nailing for Tibial Fractures
Two standards of care exist with regards to posterior splinting post-operatively. The proponents of splinting feel the additional immobilization decreases the stress on the soft tissue, subsequently preventing or limiting pain…
- Trial name
- NCT00888550
- Testing
- Post-Op Splinting, No Splinting
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Denver Health and Hospital Authority
Femoral Shaft Fracture, Tibial Shaft Fractures
Rehabilitation After Lower Extremity Nailing Trial
The goal of this clinical trial is to learn if outpatient physical therapy (PT) results in differing functional outcomes compared to a self-guided home exercise program (HEP) in tibial or femoral nail patients.
- Trial name
- ReLENT (NCT07783568)
- Testing
- Formal Physical Therapy (PT), Home Exercise Program (HEP)
- Volunteers
- 80 people
- Sponsor
- University of Chicago
Bone Fracture
A Comparative Study Between Intrathecal Dexmedetomidine VS Ketamine With Intrathecal Bupivacaine in Orthopedic Lower Limb Surgeries.
Orthopedic anaesthesia and acute postoperative pain management, two anesthesiology subspecialties,are getting more credit for reducing hospital stays, promoting functional recovery and improving patient satisfaction.
- Trial name
- NCT05751304
- Testing
- Dexmedetomidine, Ketamine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Pain
Brachial Plexus Block in Post-Op Pain Control After Distal Upper Extremity Fracture: A Prospective Randomized Study
Despite the plethora of literature suggesting that regional blockade provides adequate andimproved postoperative pain control, function and improved intraoperative and postoperative safety in proximal upper extremity surgery…
- Trial name
- NCT01968824
- Testing
- Brachial Plexus Nerve Block
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Fractures, Bone
Assessment of the Contribution of an Artificial Intelligence Tool to Help the Diagnosis of Limb Fractures in Pediatric Emergencies
Limb fracture is a common pathology in children. It represents the first complaint in traumatology among children in developed countries.
- Trial name
- FRACPED (NCT05187585)
- Testing
- radiograph interpretation without the support of the RAYVOLVE app, radiograph interpretation with the support of the RAYVOLVE app
- Where
- France
- Volunteers
- 1,200 people
- Sponsor
- Fondation Lenval
Upper Extremity Fractures, Analgesia Post Fracture
Oral Morphine Versus Ibuprofen
Children 5-17 years of age who have sustained a non-operative distal forearm (radius and/or ulna) or clavicular fracture will be randomized to receive either ibuprofen or oral morphine as needed for pain relief for the first 24…
- Trial name
- NCT01690780
- Testing
- Oral morphine, Ibuprofen
- Where
- Canada
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Naveen Poonai
Hip Fractures (ICD-10 72.01-72.2), Osteoarthritis, Knee and Hip
Population Pharmacokinetics and Pharmacodynamics of Ciprofol
The goal of this observational study is to learn how the anesthetic drug ciprofol works in older adults who are having limb surgery under general anesthesia at Shanghai Geriatric Medical Center.
- Conditions
- Hip Fractures (ICD-10 72.01-72.2), Osteoarthritis, Knee and Hip, Femoral Neck Fractures
- Trial name
- NCT07301242
- Testing
- Ciprofol
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Geriatric Medical Center
Hip Fracture
Training of Patients With Hip Fracture
The primary purpose of this study is to illustrate whether there is a difference in the 6 minutes walking test in patients with hip fractures who have received 6 vs. 12 weeks of physical training after discharge from hospital.
- Trial name
- NCT01174589
- Testing
- Strength training
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Lolland Community, Denmark
Initial Systolic Blood Pressure (mmHg), Arterial Occlusion Pressure (mmHg)
Does Anesthetic Technique Affect Pneumatic Tourniquet Pressures in Upper Limb Fracture Surgery?
In pneumatic tourniquet applications, the use of an individualized, lowest-effective tourniquet pressure (TP) has been recommended, in order to avoid pressure related complications.
- Conditions
- Initial Systolic Blood Pressure (mmHg), Arterial Occlusion Pressure (mmHg), Tourniquet Time (Minutes), Quality of Bloodless Surgical Field (4 Point Scale)
- Trial name
- NCT04710225
- Testing
- Upper limb fracture surgery and arterial occlusion pressure (AOP) estimation based tourniquet pressure (TP) setting
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Baskent University Ankara Hospital
Fractures, Bone
Cast Art for Kids With Extremity Fractures
The goal of this clinical trial is to compare casts with cast art versus those without art in children who sustain a fracture of the extremity.
- Trial name
- CAKE POP (NCT06990555)
- Testing
- Neutral White Cast, Color Wrapped Cast, Cast with Cast Art
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth