Clinical trials: Limb Injury
Tibial Fractures
Safety Study of Treatment of Leg Fractures
This study evaluates the safety of the EVOS SMALL Plating system in patients who have a fracture of the tibia requiring surgery.
- Trial name
- EVOS SMALL (NCT03881241)
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- Smith & Nephew, Inc.
Knee Injuries, Athletic Injuries
Risk Factors for Anterior Cruciate Ligament (ACL) Injury
The anterior cruciate ligament (ACL) is located inside the knee joint and provides stability to the knee. ACL injuries occur more frequently in women than men; the reason for this is unknown.
- Trial name
- NCT00124319
- Where
- 3 sites in United States
- Volunteers
- 4,800 people, healthy volunteers welcome
- Sponsor
- Steve Marshall
Ulnar Nerve Entrapment, Cubital Tunnel Syndrome
Comparison of Kinesio Taping Techniques in Ulnar Nerve Entrapment
The purpose of this study is to investigate and compare the efficacy of space-correction kinesio taping and neural technique kinesio taping-when added to a home exercise program-versus placebo taping with exercise in individuals…
- Conditions
- Ulnar Nerve Entrapment, Cubital Tunnel Syndrome, Ulnar Neuropathy at Elbow
- Trial name
- NCT07863830
- Testing
- Kinesio Taping with Space-Correction Technique, Kinesio Taping with Neural Technique, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Antalya Training and Research Hospital
Amputation, Traumatic
Feasibility of Implantable Myoelectric Sensors to Control Upper Limb Prostheses
This study will evaluate the feasibility of using implanted myoelectric sensors (IMES) to control an electromechanical prosthetic wrist and hand.
- Trial name
- IMES (NCT01901081)
- Testing
- IMES
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- The Alfred E. Mann Foundation for Scientific Research
Neonatal Brachial Plexus Palsy
Forced Lefthandedness in Neonatal Brachial Plexus Palsy (NBPP) Children
The aim of the project is to assess the neurophysiological and functional consequences of forced lefthandedness in a population with right neonatal brachial plexus palsy (NBPP).
- Trial name
- NBPP (NCT04376372)
- Testing
- Functional testing, Magnetic resonance imaging, Electromyography
- Where
- Belgium
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Distal Limbs Bones Fractures
Assessment of Distal Limbs Fractures With Cone-Beam CT Newtom 5G
ConeBeam scanner (CBCT) is a widely technique used for dental and maxillofacial imaging. Patients can be set up in a sitting or a laying position in the, Newtom 5G CBCT allowing for an analysis of the distal appendicular…
- Trial name
- FRADICOBE (NCT01796600)
- Testing
- The patients will have a conventional scanner, a reference examination, and a cone-beam scanner Newtom 5G just after the conventional scanner
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Hospices Civils de Lyon
Phantom Limb Pain
Study of Phantom Limb Pain Suppression Using Neuromodulation Methods
This study assesses the effectiveness of neuromodulation in alleviating pain through the stimulation of peripheral nerves. The research involves implanting electrodes for test stimulation of peripheral nerves (PNS - Peripheral…
- Trial name
- NCT06644807
- Testing
- Motor Cortex Stimulation, Spinal cord stimulation, Peripheral Nerve Stimulation
- Where
- 2 sites in Russia
- Volunteers
- 50 people
- Sponsor
- Skolkovo Institute of Science and Technology
Chronic Spinal Cord Injury
LIFT Home Study of Non-Invasive ARC Therapy for Spinal Cord Injury
The LIFT Home Study is an observational, single-arm study designed to assess the safety of non-invasive electrical spinal stimulation (ARC Therapy) administered by the LIFT System to treat upper extremity functional deficits in…
- Trial name
- NCT05284201
- Testing
- LIFT System
- Where
- 5 sites in United States
- Volunteers
- 17 people
- Sponsor
- ONWARD Medical, Inc.
Critical Lower Limb Ischemia, Critical Limb Ischemia
Evaluation of Carbothera in the Treatment of Foot Ulcers
Foot ulceration usually precedes more serious foot complications such as infection, gangrene or amputation. The risk of developing foot ulcers has been estimated to be higher in individuals with kidney disease.
- Conditions
- Critical Lower Limb Ischemia, Critical Limb Ischemia, Foot Ulcer, Skin Ulceration
- Trial name
- NCT02239419
- Testing
- CO2-Enriched Tap Water (Carbothera), Non-CO2-Enriched Tap Water
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Infections, Infected Wound
PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation
This is a Phase III clinical randomized control trial to investigate differences between patient with an infected nonunion treated by PO vs. IV antibiotics.
- Conditions
- Infections, Infected Wound, Nonunion of Fracture, Injury Leg
- Trial name
- POvIV2 (NCT05699174)
- Testing
- Standard of Care PO (oral) antibiotics, Standard of Care Intravenous (IV) antibiotics
- Where
- 13 sites in United States
- Volunteers
- 250 people
- Sponsor
- Major Extremity Trauma Research Consortium
Spinal Cord Injury, Spinal Cord Injury at C5-C7 Level
Nerve Transfer Surgery to Restore Upper-limb Function After Cervical Spinal Cord Injury
The goal of this prospective, open-label cohort study is to assess functional outcomes in individuals with cervical spinal cord injury who have undergone nerve transfer surgery to restore upper limb function.
- Conditions
- Spinal Cord Injury, Spinal Cord Injury at C5-C7 Level, SCI - Spinal Cord Injury, Upper Extremity Paralysis
- Trial name
- NCT05638191
- Testing
- Nerve transfer surgery
- Where
- 4 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Stroke, Quality of Life
EMG Analysis in ABI: Motor Imagery and Action
This study focuses on electromyographic analysis of upper limb muscle activation in stroke survivors during Motor Imagery (MI) and Action Observation (AO) rehabilitation techniques.
- Conditions
- Stroke, Quality of Life, Mirror Movement
- Trial name
- NCT06230718
- Testing
- Motor Imagery (MI), Action Observation (AO)
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- University of Salamanca
Acute Pain Due to Trauma
Sublingual Versus Endovenous Fentanyl for the Prehospital Analgesia in Patients With Limb Trauma on the Slope
The purpose of this study is to determine the non-inferiority of the efficacy for prehospital analgesia of sublingual administered fentanyl versus endovenous administered fentanyl for patients with limb trauma on the slope
- Trial name
- NCT03080350
- Testing
- Fentanyl sublingual, Fentanyl ev
- Where
- Italy
- Volunteers
- 108 people
- Sponsor
- Azienda Sanitaria dell'Alto Adige
Diabetic Foot Ulcer
Safety Study of Topical Doxycycline Gel for Adult Diabetic Lower Extremity Ulcers
This study is a double-blind, one center, two-arm study with a two (2) week Run-In, evaluating the efficacy of a once-daily administration of NanoDOX™ Hydrogel topically applied to diabetic ulcers in concert with professionally…
- Trial name
- NCT00764361
- Testing
- doxycycline
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- NanoSHIFT LLC
Distal Radius Fracture
Surgical Field Quality Assessment and Complications in Distal Radius Fractures Using the Minimum Inflation Tourniquet Pressure.
Analyse surgical field bleeding, surgical time, and intraoperative pain in patients undergoing osteosynthesis of distal radius fractures using ischaemia pressure calculated based on Limb Occlusion Pressure, compared with Arterial…
- Trial name
- NCT07318194
- Testing
- PNEUMATIC TOURNIQUET INFLATION PRESSURE
- Where
- Spain
- Volunteers
- 140 people
- Sponsor
- Consorci Sanitari de Terrassa
Somatic Dysfunction of Sacral Region, Somatic Dysfunction of Both Sacroiliac Joints
An Osteopathic Assessment of Lower Extremity Somatic Dysfunction in Runners
Runners often experience acute/chronic pain due to pre-existing structural somatic dysfunction and/or acquired various overuse injuries of the lower extremity, specifically affecting the ligaments, tendons, muscles and bones.
- Conditions
- Somatic Dysfunction of Sacral Region, Somatic Dysfunction of Both Sacroiliac Joints, Somatic Dysfunction of Bilateral Lower Extremities
- Trial name
- NCT05132894
- Testing
- Osteopathic Assessment
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- The Touro College and University System
Trauma Injury
Bioimpedance for Ortho Trauma
Patients with high-energy extremity trauma will undergo imaging with an EIT device in the Emergency Department, Operating Room, Orthopaedic Clinic, and In-patient hospital rooms.
- Trial name
- NCT06858488
- Testing
- Extremity Surgery
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Diabetic Foot Ulcer (DFU)
Evaluating the Efficacy of FoundationDRS Solo in Addition to Standard of Care for the Treatment of Non-healing Diabetic Foot Ulcers
The goal of this clinical trial is to learn if using FoundationDRS Solo improves healing of chronic, non-healing foot ulcers in diabetic patients.
- Trial name
- NCT07290673
- Testing
- FoundationDRS Solo, Standard of Care
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Samaritan Biologics
Spinal Cord Injuries
Technology Development for Physical Rehabilitation of Patients With Upper Extremity Motor Deficits (RePlay)
Injuries and disease processes that produce upper extremity deficits are devastating to patients and their families. One potential avenue to treat these neurological disorders is through the enhancement of neural plasticity…
- Trial name
- RePlay (NCT03621969)
- Testing
- Physical exam and medical history, Assessments, Patient Instruction and use of Device (RePlay)
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Peripheral Arterial Disease, Myocardial Injury
Cardiovascular Risk in Peripheral Artery Disease Patients Undergoing Endovascular Revascularisation
This study will investigate heart-related complications in patients with peripheral arterial disease (PAD) undergoing endovascular revascularization procedures to improve blood flow in the legs.
- Conditions
- Peripheral Arterial Disease, Myocardial Injury, Troponin, NT-proBNP
- Trial name
- RISK (NCT07599540)
- Where
- Slovenia
- Volunteers
- 500 people
- Sponsor
- University Medical Centre Ljubljana