Clinical trials: Limb Pain, Phantom
Post-Amputation Pain, Phantom Limb Pain
Electrical Nerve Block for Amputation Pain
The purpose of the clinical trial is to learn whether electrical nerve block via the Altius System is a safe and effective treatment for patients with post-amputation pain.
- Conditions
- Post-Amputation Pain, Phantom Limb Pain, Residual Limb Pain, Stump Pain
- Trial name
- NCT02221934
- Testing
- Altius
- Where
- 22 sites in United States
- Volunteers
- 607 people
- Sponsor
- Neuros Medical, Inc.
Pain, Neuropathic, Amputation Neuroma
Surgical Treatments for Neuroma Pain in Amputees
Amputees often suffer from relentless pain and disability resulting from symptomatic neuromas within the amputation stumps. When conservative measures fail to address these symptoms, two contemporary surgical approaches to treat…
- Conditions
- Pain, Neuropathic, Amputation Neuroma, Phantom Limb Pain
- Trial name
- STOCAP (NCT04204668)
- Testing
- TMR, RPNI, VDMT
- Where
- 2 sites in United States
- Sponsor
- Johns Hopkins University
Phantom Limb Syndrome With Pain
The Impact of a Virtual Reality Environment on Phantom Limb Pain
Phantom limb pain occurs in the majority of people who lose a limb. It significantly affects quality of life and is hard to manage.
- Trial name
- NCT03934528
- Testing
- Virtual environment activity
- Where
- United Kingdom
- Sponsor
- University of Manchester
Phantom Limb Pain
Treatment of Phantom Limb Pain by Intensive Visual Simulation Therapy
Phantom limb pain (PLP) is reported by as much as 80 % of patients following an amputation. There is increasing knowledge of the relation between PLP and maladaptive changes in brain cortical regions.
- Trial name
- NCT06483035
- Testing
- Intensive Visual Simulation (IVS), Usual Care (UC)
- Where
- Norway
- Volunteers
- 38 people
- Sponsor
- Oslo Metropolitan University
Pain Management
A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 2)
The purpose of this study is to compare the effectiveness of innovative intervention of breathing controlled electrical stimulation (BreEStim) and conventional electrical stimulation (EStim) in management of neuropathic phantom…
- Trial name
- NCT04750538
- Testing
- BreEStim 120, BreEStim 240
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pain Management
A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 3)
The purpose of this study is to compare the effectiveness of innovative intervention of breathing controlled electrical stimulation (BreEStim) and conventional electrical stimulation (EStim) in management of neuropathic phantom…
- Trial name
- NCT04751526
- Testing
- BreEStim 240, EStim 240
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- The University of Texas Health Science Center, Houston
Phantom Limb Pain, Phantom Pain
VR to Evaluate Phantom Limb Pain
The objective of this study is to develop a virtual rehabilitation system that can be used to effectively treat Phantom Limb Pain (PLP) within the research setting and for at-home use by individuals with upper and lower extremity…
- Conditions
- Phantom Limb Pain, Phantom Pain, Phantom Sensation, Phantom Limb Syndrome With Pain
- Trial name
- NCT05915065
- Testing
- Coapt Phantom Limb Pain Management System
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Shirley Ryan AbilityLab
Pain Management
A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 1)
The purpose of this study is to compare the effectiveness of innovative intervention of breathing controlled electrical stimulation (BreEStim) and conventional electrical stimulation (EStim) in management of neuropathic phantom…
- Trial name
- NCT04750525
- Testing
- BreEStim, EStim
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pain, Amputation
Sciatic Block in Contralateral Limb Phantom and Residual Limb Pain
Participants with chronic, refractory phantom limb pain (PLP) or residual limb pain (RLP) for more than 6 months will be enrolled in this clinical trial.
- Trial name
- NCT05046639
- Testing
- 10 mL 2% lidocaine, 10 mL preservative free saline
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Northwestern University
Phantom Limb Pain
Peripheral Magnetic Stimulation (PMS) Effects on Somatosensory Perception in Patients with Upper Limb Amputation
The study investigates the capabilities of peripheral magnetic stimulation (PMS) as a tool for creating somatosensory sensations of various submodalities and analyzing the dynamics of bioelectric signals of the brain (using…
- Trial name
- NCT06813937
- Testing
- Procedure: Peripheral Magnetic Stimulation (PMS), Electroencephalography (EEG)
- Where
- Russia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Skolkovo Institute of Science and Technology
Residual Limb Pain, Amputation Neuroma
Surgical Treatments for Postamputation Pain
This is a double-blind randomised controlled trial (RCT) which compares the effectiveness of three surgical techniques for alleviating residual limb pain (RLP), neuroma pain and phantom limb pain (PLP).
- Conditions
- Residual Limb Pain, Amputation Neuroma, Phantom Limb Pain, Pain, Neuropathic
- Trial name
- NCT05009394
- Testing
- Targeted Muscle Reinnervation (TMR), Regenerative Peripheral Nerve Interface (RPNI), Standard neuroma treatment, neuroma excision, and muscle burying
- Where
- 9 sites in United States, Australia and 5 more
- Volunteers
- 110 people
- Sponsor
- Prometei Pain Rehabilitation Center
Phantom Limb Pain, Neuroma Amputation
C-RFA of Residual Limb Neuroma
To assess changes in pain, physical function, and health-related quality of life in patients with post-amputation neuroma-associated residual limb pain after cooled radiofrequency ablation.
- Trial name
- NCT04538417
- Testing
- Cooled Radiofrequency Ablation
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Utah
Phantom Limb Pain, Amputation
TITAN Trial: Reducing Phantom Limb Pain in People with Amputations
The goal of this clinical trial is to investigate the effectiveness of two rehabilitation programs for individuals who have undergone amputations and are experiencing phantom limb pain.
- Trial name
- TITAN (NCT06167330)
- Testing
- Progressive rehabilitation program, Stimulation devices
- Where
- Australia
- Volunteers
- 208 people
- Sponsor
- Neuroscience Research Australia
Phantom Limb Pain
Evaluation of Neuroprosthesis with Sensory Feedback for Modulation of Phantom Limb Pain and Enhancing Quality of Life
This clinical trial is designed to assess the effectiveness of advanced neuromodulation techniques in reducing phantom limb pain by improving sensory feedback in bionic prostheses.
- Trial name
- NCT06702904
- Testing
- Peripheral Nerve Stimulation, Spinal cord stimulation, Dorsal Root Ganglion Stimulation
- Where
- 2 sites in Russia
- Volunteers
- 50 people
- Sponsor
- Skolkovo Institute of Science and Technology
Phantom Limb Pain, Amputation
Effect of Femoral and Sciatic Nerve Blocks, Combined with General Anesthesia, in Postoperative Pain Levels and Phantom Limb Pain Development in Patients Undergoing Lower Limb Amputation
The goal of this observational study is to determine the effect of femoral and sciatic nerve blocks, combined with general anesthesia, in postoperative pain levels and phantom limb pain development in patients undergoing lower…
- Conditions
- Phantom Limb Pain, Amputation, Anesthesia, Local
- Trial name
- NCT06693427
- Testing
- Peripheral Nerve Block
- Where
- Greece
- Volunteers
- 72 people
- Sponsor
- DIMITRIOS KATSAROS
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Phantom Limb Pain
Study of Phantom Limb Pain Suppression Using Neuromodulation Methods
This study assesses the effectiveness of neuromodulation in alleviating pain through the stimulation of peripheral nerves. The research involves implanting electrodes for test stimulation of peripheral nerves (PNS - Peripheral…
- Trial name
- NCT06644807
- Testing
- Motor Cortex Stimulation, Spinal cord stimulation, Peripheral Nerve Stimulation
- Where
- 2 sites in Russia
- Volunteers
- 50 people
- Sponsor
- Skolkovo Institute of Science and Technology
Phantom Limb Pain, Amputation
Phantom Limb Pain in Amputees After the 2023 Türkiye Earthquake
The goal of this observational study is to investigate the prevalence and persistence of phantom limb pain (PLP) among amputees who experienced limb loss due to injuries sustained during the 2023 Türkiye earthquake.
- Conditions
- Phantom Limb Pain, Amputation, Pain Management, Earthquake
- Trial name
- NCT06617728
- Testing
- Intervention 1: Regional Analgesia, Intervention 2: Intravenous (IV) Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Mesut Bakır
Phantom Limb Pain, Residual Limb Pain
Pulsed Electromagnetic Fields for Post-Amputation Pain
Pulsed electromagnetic field therapy is a possible method of pain control involving the application of electromagnetic energy (also termed nonthermal, pulsed, shortwave radiofrequency therapy).
- Trial name
- NCT05392803
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of California, San Diego
Amputation, Traumatic, Pain, Phantom
Feasibility of Using an App for Managing Phantom Limb Pain Associated with Combat Injury in Ukraine (PAMELA)
In Ukraine, since the beginning of the full-scale war on February 24, 2022, a large number of individuals have lost a limb(s). Many of these amputees cannot access appropriate care in terms of pain management and rehabilitation.
- Conditions
- Amputation, Traumatic, Pain, Phantom, Pain, Acute, Pain, Chronic
- Trial name
- PAMELA (NCT06604507)
- Testing
- non-pharmacological app
- Where
- 5 sites in Ukraine
- Volunteers
- 200 people
- Sponsor
- Winfried Meißner