Clinical trials: Limb Pain, Phantom
Phantom Limb Pain, Phantom Pain
VR to Evaluate Phantom Limb Pain
The objective of this study is to develop a virtual rehabilitation system that can be used to effectively treat Phantom Limb Pain (PLP) within the research setting and for at-home use by individuals with upper and lower extremity…
- Conditions
- Phantom Limb Pain, Phantom Pain, Phantom Sensation, Phantom Limb Syndrome With Pain
- Trial name
- NCT05915065
- Testing
- Coapt Phantom Limb Pain Management System
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Shirley Ryan AbilityLab
Phantom Limb, Leg Amputation
Leg Amputation and Continuous Sciatic Nerve Block
Analgesia following leg amputation is based on morphine administration. For elderly patients of ASA physical status 2 or 3, morphine sparing is possible when perinervous block techniques are used.
- Trial name
- CAPDAF (NCT00427947)
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Bordeaux
Postoperative Pain
Preoperative (Pre-amputation) Cryoanalgesia to Improve Post-amputation Phantom Limb Pain
Investigators will evaluate preamputation cryoanalgesia on pain, mobility, opioid use and general physical and emotional disability using a pilot randomized trial design, to explore the amount and variability of improvement on…
- Trial name
- NCT06284109
- Testing
- Cryoanalgesia
- Where
- United States
- Sponsor
- The Cleveland Clinic
Phantom Limb Pain
Short Term Effect of Post Surgical Treatment of Mirror Therapy of Phantom Limb Pain
The aim of the study is the measurement of the short term effect of post surgical mirror therapy concerning pain intensity and frequency of patients with upper or lower amputation in comparison to standard occupational or…
- Trial name
- PPSS (NCT01913899)
- Testing
- Occupational/ physical therapy, Mirror therapy
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Ruhr University of Bochum
Phantom Limb Pain (PLP)
Immersive Healing: The Therapeutic Potential of Virtual Reality
Phantom limb pain (PLP) is a significant and pervasive issue among upper limb amputees, severely impacting their quality of life.
- Trial name
- NCT06077227
- Testing
- virtual reality therapy, matched control group
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wake Forest University Health Sciences
Phantom Limb Pain
Assessing the Feasibility of a Virtual Reality Intervention for Phantom Pain Immediately Following Lower Limb Amputation
The goal of this observational study is to see whether a new virtual reality (VR) program meant to treat phantom limb pain (PLP) is feasible to people immediately following lower limb amputation.
- Trial name
- NCT06638918
- Testing
- Virtual Reality
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Phantom Limb Pain
Sensory Retraining for Phantom Limb Pain
86-87% of people who have had an amputation still feel pain in the limb that has been amputated - Phantom limb pain (PLP). Sensory retraining is a form of treatment for PLP where a special form of electrical stimulation is…
- Trial name
- PHANTOM RELIEF (NCT04103983)
- Testing
- Sensory retraining device
- Where
- United Kingdom
- Volunteers
- 109 people
- Sponsor
- Teesside University
Pain, Pain Syndrome
Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Central Neuropathy of Any Genesis
Over the last years a rising medical need for treatment of chronic pain was identified. Based on previous findings indicating the pain modulating effects of cannabinoids in chronic pain disorders, this clinical trial investigates…
- Conditions
- Pain, Pain Syndrome, Pain, Chronic, Chronic Pain
- Trial name
- NCT06072001
- Testing
- Adezunap (AP707)
- Where
- Germany
- Volunteers
- 558 people
- Sponsor
- Apurano Pharmaceuticals GmbH
Phantom Limb Pain After Amputation, Chronic Pain Due to Injury
Negative Pressure Wound Therapy as a Predictor of Persistent Pain After War-Related Trauma
War-related trauma frequently causes complex soft tissue injuries that require repeated surgical treatment and advanced wound management techniques such as Negative Pressure Wound Therapy (NPWT).
- Conditions
- Phantom Limb Pain After Amputation, Chronic Pain Due to Injury, Postoperative Pain, Trauma (Including Fractures)
- Trial name
- NPWT-Pain Stud (NCT07475897)
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Charitable Organisation Charitable Fund Superhumans (Co Cf Superhumans)
Amputation of Lower Limb
Gabapentin in Phantom and Stump Pain
To investigate whether gabapentin can prevent phantom and stump pain after amputation.
- Trial name
- NCT00169013
- Testing
- Gabapentin
- Where
- Denmark
- Sponsor
- Danish Pain Research Center
Phantom Limb Pain
Acupuncture for Phantom Limb Pain
Phantom pain is a common complication following limb amputation, and is thought to result from a system of pathophysiological mechanisms - peripheral, spinal, central and psychological.
- Trial name
- NCT00460161
- Testing
- acupuncture
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Shaare Zedek Medical Center
Lower Limb Amputation
Phantom Exercise for Lower Limb Amputees
In this research, the aim is to find out the effects of phantom exercises in terms of pain, mobility and quality of life among lower-limb amputees having phantom limb pain.
- Trial name
- NCT04285138
- Testing
- phantom limb exercise, conventional treatment
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Lower Limb Amputation Below Knee (Injury)
Descriptive Study of Receptive Fields in Lower Limb Amputees
It has been observed that patients subjected to amputations develop so called receptive fields, which time of occurrence and localization over time are yet not examined systematically.
- Trial name
- NCT03348605
- Testing
- Phantom Stimulator, Cort X Sensorics, Spaichingen, Germany
- Where
- Switzerland
- Volunteers
- 35 people
- Sponsor
- Rehaklinik Bellikon
Phantom Limb Pain, Neuropathic Pain
Nabilone for the Treatment of Phantom Limb Pain
The purpose of this proposed study is to conduct a randomized double-blind placebo controlled trial assessing the benefit of nabilone in pain management and improvement of quality of life in patients with phantom limb pain.
- Trial name
- NCT00699634
- Testing
- Nabilone
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Neuralgia
P4 (Pregabalin for Peripheral Posttraumatic Pain)
To evaluate the efficacy of pregabalin compared to placebo in the treatment of posttraumatic peripheral neuropathic pain
- Trial name
- P4 (NCT00292188)
- Testing
- pregabalin
- Where
- 44 sites in Belgium, Canada and 9 more
- Volunteers
- 255 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Phantom Limb Pain, Amputation
Effect of Femoral and Sciatic Nerve Blocks, Combined with General Anesthesia, in Postoperative Pain Levels and Phantom Limb Pain Development in Patients Undergoing Lower Limb Amputation
The goal of this observational study is to determine the effect of femoral and sciatic nerve blocks, combined with general anesthesia, in postoperative pain levels and phantom limb pain development in patients undergoing lower…
- Conditions
- Phantom Limb Pain, Amputation, Anesthesia, Local
- Trial name
- NCT06693427
- Testing
- Peripheral Nerve Block
- Where
- Greece
- Volunteers
- 72 people
- Sponsor
- DIMITRIOS KATSAROS
Targeted Sensory Reinervation, Amputation
Targeted Sensory Reinnervation (TSR) in Hand Amputation
If a person has to have a part of their body amputated, in this case their hand, the patient then lacks information about the missing limb, which in many cases leads to pain that severely restricts their quality of life and…
- Conditions
- Targeted Sensory Reinervation, Amputation, Phantom Pain
- Trial name
- NCT06249594
- Testing
- targeted sensory reinervation
- Where
- 2 sites in Austria, Italy
- Volunteers
- 3 people
- Sponsor
- Brixsana Private Clinic - Centro di Chirurgia Plastica, Estetica ed Ricostruttiva con Chirurgia dell
Pain, Amputation
Sciatic Block in Contralateral Limb Phantom and Residual Limb Pain
Participants with chronic, refractory phantom limb pain (PLP) or residual limb pain (RLP) for more than 6 months will be enrolled in this clinical trial.
- Trial name
- NCT05046639
- Testing
- 10 mL 2% lidocaine, 10 mL preservative free saline
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Northwestern University
Phantom Limb Pain After Amputation, Lower Limb Amputation
Operant Conditioning of Sensory Brain Responses to Reduce Phantom Limb Pain in People With Limb Amputation
The study will investigate the application of a non-pharmacological operant conditioning approach to reduce phantom limb pain (PLP). PLP afflicts 60-90% people who have lost a limb.
- Conditions
- Phantom Limb Pain After Amputation, Lower Limb Amputation, Upper Limb Amputation, Phantom Pain
- Trial name
- OCS-PLP (NCT05880251)
- Testing
- Operant Conditioning with Peripheral Stimulation, Control Group with Peripheral Stimulation Only
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Phantom Limb Pain
Examining Brain Changes Using Functional Magnetic Resonance Imaging (fMRI) in Amputees With Phantom Limb Pain Following Mirror Therapy
Almost everyone who has a traumatic limb amputated will experience a phantom limb - the vivid impression that the limb not only still is present, but also in many cases, painful.
- Trial name
- NCT00662415
- Testing
- mirror-box treatment, observation
- Where
- 2 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- United States Department of Defense