Clinical trials: Limitation, Mobility
Mobility Limitation, Motor Activity
Cognitive Remediation to Improve Mobility in Sedentary Seniors
The investigators propose to conduct a single-blind randomized clinical trial to test the efficacy of a computerized cognitive remediation intervention program on improving locomotion in sedentary seniors, a group at an…
- Conditions
- Mobility Limitation, Motor Activity, Difficulty Walking, Cognitive Ability General
- Trial name
- CREM (NCT02567227)
- Testing
- Cognitive Remediation, Active Control
- Where
- United States
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Multiple Sclerosis, Ambulation Difficulty
Effects of a Home Based Walking Program Using Rhythmic Auditory Stimulation in Patients With Multiple Sclerosis
Rhythmic Auditory Stimulation (RAS) is a music therapy technique that provides rhythmic auditory cues (like a beat) to help improve patients' movements, especially when walking.
- Trial name
- NCT02065284
- Testing
- Rhythmic Auditory Stimulation (RAS)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- The Cleveland Clinic
Stroke Syndrome, Balance; Distorted
Validity Reliability of The Dubousset Functional Test in Stroke Patients
Increased muscle tone, decreased normal range of motion, and functional impairments may result in decreased load on the affected limb, deviations in gait patterns, balance and coordination disorders in individuals with stroke.
- Conditions
- Stroke Syndrome, Balance; Distorted, Walking, Difficulty
- Trial name
- NCT04627558
- Testing
- stroke patients, balance assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Mobility Limitation, Aging
HOMEStudy: Development of a Home-based Self-delivered Prehabilitation Intervention to Proactively Reduce Fall Risk in Older Adults
Older adults often have difficulty performing complex walking tasks leading to increased fall incidence and subsequent injury. Even in the best clinical settings, it may not be possible for patients or clinicians to dedicate the…
- Trial name
- NCT05583578
- Testing
- Home-based mobility testing and active tDCS
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Florida
Spinal Cord Injuries, Walking, Difficulty
First Report of a New Exoskeleton in Incomplete Spinal Cord Injury
The goal of this clinical trial is to compare the effects of exoskeletal robotic therapy and conventional exercise therapy in incomplete spinal cord injury (SCI).
- Trial name
- NCT06137456
- Testing
- Exoskeletal robotic therapy for walking., Conventional exercise therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people
- Sponsor
- Ankara City Hospital Bilkent
Stroke, Ischemic
Effects of PNF Patterns Training on Trunk Balance, and Gait in Chronic Stroke Patients
To determine the effects of PNF patterns Training on trunk balance and gait in chronic stroke patients.
- Trial name
- NCT05221112
- Testing
- diagonal pattern training, single plane training
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Parkinson Disease (PD), Gait Disorders
Effects of Transcranial Direct Current Stimulation Combined With Nordic Walking on Gait and Balance in Parkinson's Disease
Parkinson's disease can cause slow or unsteady walking and balance problems that raise the risk of falls. This study will test whether adding a gentle, non-invasive brain stimulation called transcranial direct current stimulation…
- Conditions
- Parkinson Disease (PD), Gait Disorders, Postural Balance
- Trial name
- tDCS+NW-PD (NCT07381907)
- Testing
- Transcranial Direct Current Stimulation (tDCS), active, Standardized Nordic Walking program
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Metodista de Piracicaba
Parkinson Disease
The Effects of 24-Weeks Community-based Brisk Walking in People With Parkinson's Disease
The goal of this clinical trial is to investigate if brisk walking can improve walking function in people with Parkinson's disease and what kind of brisk walking intervention that is most effective.
- Trial name
- We-Walk-PD (NCT06707402)
- Testing
- WALK, ACTIVE, CON
- Where
- Denmark
- Volunteers
- 129 people
- Sponsor
- University of Aarhus
Aging, Mobility Limitation
Development and Evaluation of TRIVEL Smart Bike Training Prescription Programs.
This pilot A-B study aims to develop and validate personalized training programs for older adults with decreased mobility on a Semi-Reclining Intelligent Stationary Bike prototype.
- Trial name
- NCT06386536
- Testing
- Intelligent stationary bike, Conventional stationary bilke
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sylvie Nadeau
PHYSIOLOGICAL PHENOMENA, Homeostasis
Truway Whole-Body Digital Twin and Physiologic Resilience Study (TRU-OMNIBODY)
TRU-OMNIBODY is a prospective observational study designed to develop and independently validate a research-only whole-body digital twin.
- Conditions
- PHYSIOLOGICAL PHENOMENA, Homeostasis, Physical Functional Performance, Cardiorespiratory Fitness
- Trial name
- TRU-OMNIBODY (NCT07805044)
- Testing
- Standardized Physiologic Resilience Challenge, Multimodal Whole-Body Physiologic Monitoring, Research-Only Whole-Body Digital Twin Analysis
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Mobility Limitation
Enhancing Independence Using Group-based Community Interventions for Healthy AGing in Elders: the ENGAGE Pilot Study
This study will be conducted to determine the safety and feasibility of translating a physical activity intervention (LIFE Study) into a community setting.
- Trial name
- ENGAGE (NCT03430271)
- Testing
- Physical Activity Intervention, Healthy Aging Intervention
- Where
- 2 sites in United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Tufts University
Parkinson Disease, Walking, Difficulty
Model-based Cueing-as-needed for Walking in Parkinson's Disease
Correcting of the lack of regularity in steps is a key component of gait rehabilitation in Parkinson's disease. The proposal is to introduce adaptive spatial auditory cueing (ASAC) based on verbal instruction "lengthen the step"…
- Conditions
- Parkinson Disease, Walking, Difficulty, Gait, Festinating
- Trial name
- GAITPARK (NCT06073028)
- Testing
- 20-minute gait training
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Henri Mondor University Hospital
Hip Fracture Surgery, Mobility Limitation
Feasibility of a Co-designed Mobility Intervention After Hip Fracture Surgery
This clinical study examines whether a co-designed mobility intervention can be delivered in routine hospital care after hip fracture surgery.
- Conditions
- Hip Fracture Surgery, Mobility Limitation, Postoperative Rehabilitation
- Trial name
- HIP-ME-UP (NCT07561164)
- Testing
- HIP-ME-UP mobility intervention
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Hvidovre University Hospital
Cerebrovascular Stroke, Cerebral Stroke
The Effects of Body Weight Supported Treadmill Training On Balance In Stroke Patients
Stroke is one of the most common causes of acquired adult disability. The majority of stroke survivors have mobility difficulties such as poor standing, decreased walking speed, balance disturbances, and increased risk for falls.
- Conditions
- Cerebrovascular Stroke, Cerebral Stroke, Cerebrovascular Accident
- Trial name
- NCT02735148
- Testing
- Body Weight Supported Treadmill Training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul University
Peripheral Artery Disease, Intermittent Claudication
Improving Mobility After Revascularization in Peripheral Artery Disease
Lower extremity revascularization combined with supervised exercise significantly improves walking performance compared to revascularization alone in people who have PAD without limb threatening ischemia.
- Conditions
- Peripheral Artery Disease, Intermittent Claudication, Peripheral Vascular Disease, Mobility Limitation
- Trial name
- IMPACT PAD (NCT06686121)
- Testing
- Home Based Exercise, Nitrate Rich Beetroot Juice, Attention Control
- Where
- 8 sites in United States
- Volunteers
- 386 people
- Sponsor
- Northwestern University
Total Knee Arthroplasty Recovery
Effects of Progressive Restricted Blood Flow Exercises in Post Total Knee Arthroplasty
Total knee arthroplasty (TKA) is a commonly performed procedure for advanced knee osteoarthritis. Despite successful surgery, many patients experience postoperative impairments including pain, reduced range of motion (ROM)…
- Trial name
- TKA PBFR (NCT07601906)
- Testing
- Blood Flow Restriction Exercises and Conventional Physical Therapy, Conventional Physical Therapy alone
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Mobility Limitation
Mobility Impairment in the Northern Region of Malawi
The purpose of this study is to investigate whether Lofstrand or axillary crutches are better suited to treat mobility impairments and improve physical activity levels in rural, resource-limited, settings like the Northern Region…
- Trial name
- NCT04074252
- Testing
- Lofstrand Crutches, Axillary Crutches
- Where
- United States
- Sponsor
- University of California, Los Angeles
Parkinson Disease, Walking, Difficulty
BeatPark: Self-rehabilitation in Walking With Parkinson's Disease
Physical activity has beneficial effects on the quality of walking for persons with Parkinson's disease (PD). However, regular physical activity is still limited in most patients' daily lives.
- Trial name
- BeatPark (NCT04543058)
- Testing
- BeatPark Application, BeatPark Application without synchronized music, BeatPark Application without music
- Where
- France
- Volunteers
- 396 people
- Sponsor
- Clinique Beau Soleil
Aging, Mobility Limitation
Evaluating Implementation and Impact of Provincial Scale-up of the Adapted Choose to Move (CTM) Program
Choose to Move (CTM) is a 3-month, choice-based health-promoting program for low active older adults being scaled-up across British Columbia (BC), Canada.
- Conditions
- Aging, Mobility Limitation, Physical Inactivity, Loneliness
- Trial name
- NCT06446414
- Testing
- Choose to Move
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Dementia, Memory Loss
Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia
This project aims to examine the efficacy of remote, caregiver-led tES/brain stimulation intervention targeted to improve memory, mobility, and executive functioning among older adults with mild cognitive impairment or mild…
- Conditions
- Dementia, Memory Loss, Alzheimer Disease, Executive Dysfunction
- Trial name
- ACDCStim (NCT05661084)
- Testing
- Transcranial alternating current stimulation (tACS) (active); Transcranial direct current stimulation (tDCS) (active)
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Hebrew SeniorLife