Clinical trials: Limitation, Mobility
Mobility Limitation, Cognitive Impairment
Combining tDCS and Neurorehabilitation to Treat Age-related Deficits of Mobility and Cognition: UPfront Walking Study
Loss of mobility and cognitive ability are serious conditions that threaten the independence of older adults. The objective of this study is to initiate a line of research to develop a novel therapeutic intervention to enhance…
- Trial name
- NCT03122236
- Testing
- Neurorehabilitation of Standard Walking, Neurorehabilitation of Complex Walking, Active Transcranial Direct Current Stimulation (Active tDCS)
- Where
- 3 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Florida
Stroke, Chronic Stroke
Reflex Excitability in Post-stroke Stiff-Knee Gait
The purpose of this study is to examine the reflex excitability of the rectus femoris in individuals with and without post-stroke Stiff-Knee gait.
- Conditions
- Stroke, Chronic Stroke, Gait, Hemiplegic, Gait, Spastic
- Trial name
- NCT04947865
- Testing
- Peripheral nerve stimulation, Commercial knee brace
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Old Adults, Sleep Quality
Kava Aging and Mobility Study
The goal of this clinical trial is to learn if AB-free kava works to improve mobility and physical function in older adults with sleep difficulties. It will also learn about the safety of AB-free kava.
- Conditions
- Old Adults, Sleep Quality, Kava, Mobility Impairment
- Trial name
- NCT07219186
- Testing
- AB-free kava
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Florida
Hereditary Multiple Osteochondromas
Functional and Morphological Characterization of Multiple Osteochondromas Disorder
The main purpose of the study is the characterization of functional and morphological alterations due to multiple osteochondromas in a pediatric and adult population through the identification of relevant anthropometric and…
- Trial name
- MAMBO (NCT06703736)
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Gait Disorder, Postural Balance
Effects of Tai Chi on Postural Balance and Quality of Life in the Elderly With Gait Disorder
The goal of this intervention study was to test balance ability and quality of life in older adults with gait problems. The main questions it aims to answer are: 1.
- Trial name
- NCT06046911
- Testing
- Tai Chi, Daily activity group
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Neck Pain, Posterior, Headache
Dry Needling of the M. Obliquus Capitis Inferior on Rotational Mobility and Headache Related Outcome Measures in CH.
An experimental study will be conducted to evaluate the effect of dry needling on the M. Obliquus capitis inferior on rotational mobility and headache realted outcome measures in patients with cervicogenic headache.
- Conditions
- Neck Pain, Posterior, Headache, Mobility Limitation
- Trial name
- NCT05074381
- Testing
- Dry Needling
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- University Ghent
Mobility Limitation
Does Dosage Matter: Ride-on Cars to Enhance Social-mobility Function and Motivation in Toddlers With Motor Disabilities
Modified ride-on toy cars (ROCs) have been viewed as one Maker Movement and become an innovative, alternative option to enhance independent mobility and socialization in young children with disabilities in the recent years.
- Trial name
- NCT04468451
- Testing
- A 48-hour ROC training program with a standing posture, A 24-hour ROC training program with a standing posture, A regular therapy program without receiving any ROC training
- Where
- Taiwan
- Volunteers
- 13 people
- Sponsor
- Chang Gung Memorial Hospital
Mobility Limitation, Motor Activity
Cognitive Remediation to Improve Mobility in Sedentary Seniors
The investigators propose to conduct a single-blind randomized clinical trial to test the efficacy of a computerized cognitive remediation intervention program on improving locomotion in sedentary seniors, a group at an…
- Conditions
- Mobility Limitation, Motor Activity, Difficulty Walking, Cognitive Ability General
- Trial name
- CREM (NCT02567227)
- Testing
- Cognitive Remediation, Active Control
- Where
- United States
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Pressure Ulcer, Ankle, Prosthesis User
Limb Health and Socket Pressure in Response to Powered Ankle Protheses
this project seeks to understand and quantify the effects of powered transtibial prostheses on socket loading and direct measures of residual limb health so as to inform the optimization of prosthesis fit.
- Conditions
- Pressure Ulcer, Ankle, Prosthesis User, Prosthesis Durability, Mobility Limitation
- Trial name
- OPORP (NCT05112679)
- Testing
- PROPRIO FOOT® by Ossur & Empower ankle by Ottobock
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Indiana University
Cerebral Palsy
ImGTS for Patients With Cerebral Palsy and With Mobility Limitations (Phase 2)
The proposed research project aims to answer the question "Are immersive technology systems effective in the rehabilitation management of pediatric patients with cerebral palsy and with mobility limitations?".
- Trial name
- NCT06100341
- Testing
- Virtual reality
- Where
- Philippines
- Volunteers
- 30 people
- Sponsor
- Augmented eXperience E-health Laboratory
Prostate Cancer, Ambulation Difficulty
Use of Pedometer Following Radical Prostatectomy
This is a study to evaluate whether use of a pedometer following radical prostatectomy decreases post-operative narcotic use and time to return of bowel function.
- Trial name
- NCT04206280
- Testing
- Use of a pedometer following surgery, Standard of care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Benaroya Research Institute
Aging, Mobility Limitations
Life 2: Improving Fitness and Function in Elders
The purpose of this study is to determine whether a 12-month physical activity counseling program, compared to usual care, improves physical performance in a sample of older veterans.
- Trial name
- Project LIFE (NCT00435188)
- Testing
- Multi-component physical activity counseling program
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Ambulatory Difficulty
Efficacy and Safety of Sugammadex in High-Risk Ambulatory Surgeries
In this randomized controlled study, the investigators hypothesize that sugammadex is superior to neostigmine in higher risk patients undergoing laparoscopic outpatient surgery in an urban, stand-alone ambulatory surgery center.
- Trial name
- Sugammadex (NCT03944473)
- Testing
- Sugammadex, Neostigmine
- Sponsor
- Montefiore Medical Center
Mobility Limitation
A Study to Assess the Anti-fatigability Effect of CK-2127107 in Elderly Male and Female Subjects With Limitations in Mobility
The purpose of this study is to investigate the effect of CK-2127107 versus placebo on skeletal muscle fatigue assessed as change from baseline versus 14 days of treatment in sum of peak torque during isokinetic knee extensions.
- Trial name
- NCT03065959
- Testing
- reldesemtiv
- Where
- 5 sites in United States
- Volunteers
- 42 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Loneliness, Social Isolation
The Emotional, Physical and Cognitive Benefits of Purposeful Green Space Activities on Seniors
This project explores if various nature based activities can lead to acute improvements in emotional, physical and cognitive health outcomes and encouraging senior center (JABA) service users to return to a safe environment.
- Conditions
- Loneliness, Social Isolation, Mood, Well Aging
- Trial name
- NCT04913363
- Testing
- Green space
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Hemophilia
Blood Flow Restriction in Improving Muscle Strength of Patients With Hemophilic Knee Arthropathy
Background. The main physical sequela of patients with hemophilia is the development of a progressive, degenerative intra-articular lesion, known as hemophilic arthropathy).
- Trial name
- NCT06261632
- Testing
- Blood flow restriction
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Stroke, Spinal Cord Injuries
ZEPU-AI3 Lower Limb Feedback Robot Training Study
Lower limb motor dysfunction resulting from stroke, spinal cord injury, or other neurological disorders substantially limits mobility, independence, and quality of life.
- Conditions
- Stroke, Spinal Cord Injuries, Gait Disorders
- Trial name
- ZEPUAI3RCT (NCT07705906)
- Testing
- ZEPU-AI3 Lower Limb Feedback Training and Evaluation Robot, Conventional Rehabilitation
- Where
- Bangladesh
- Volunteers
- 32 people
- Sponsor
- Bangladesh Medical University
Multiple Sclerosis, Mobility Limitation
Innovative Approaches to Enhance Balance and Neuroplasticity in Multiple Sclerosis
This study will evaluate the effects of combining balance training with electrical stimulation techniques in individuals with Multiple Sclerosis (MS).
- Conditions
- Multiple Sclerosis, Mobility Limitation, Balance; Distorted, Gait
- Trial name
- NCT07174973
- Testing
- Balance training with FES, Balance training wiith combined neuromodulation (TSCS+FES), Balance training only
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University Health Network, Toronto
Mobility Limitation
Testing the Dose-response of Coordination Training for Older Adults.
There is an urgent need for interventions to reduce mobility limitations that affect over 15 million older adults and contribute to falls, disability, hospitalization and death. This training will give Dr.
- Trial name
- NCT03629730
- Testing
- Coordination training
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Multiple Sclerosis
Effects of Targeted Lower Extremity Joint Training on Multiple Sclerosis (MS) Gait Abnormalities
This study is being done to test the possible benefits of task-specific focused ankle training using the Ankle-Bot on subjects with Multiple Sclerosis who have "foot-drop." The study also compares the effectiveness of…
- Trial name
- NCT00906737
- Testing
- Ankle-bot, Conventional focused ankle therapy
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Mount Sinai Rehabilitation Hospital