Clinical trials: Limitation, Mobility
Pelvic Fracture, Insufficiency Fractures
Titanium Fusion Implant in Combination With Trans-iliac Screws for Insufficiency Fractures of the Pelvis
Many approaches to the surgical treatment of OF-P have been tried, but no one method has stood out as particularly successful. The placement of three implants, including implants that could minimise motion in the sacroiliac joint…
- Conditions
- Pelvic Fracture, Insufficiency Fractures, Mobility Limitation
- Trial name
- TIKTIS (NCT05367505)
- Testing
- iFuse-3D implant
- Where
- 3 sites in Germany
- Volunteers
- 50 people
- Sponsor
- University of Witten/Herdecke
Frailty, Sarcopenia
Resistance-Based Multicomponent Training Plus Nutrition Supplementation for Intrinsic Capacity and Disability Risk in Chinese Rural Older Adults
This study is a five-arm, parallel-group, assessor-blinded randomized controlled trial designed to evaluate the effects of resistance-dominant multicomponent training combined with nutritional supplementation on intrinsic…
- Conditions
- Frailty, Sarcopenia, Mobility Limitation, Nutritional Risk
- Trial name
- NCT07660653
- Testing
- Routine Health Education, Leucine-Enriched Whey Protein and Vitamin D Supplementation, Progressive Resistance Training
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Capital University of Physical Education and Sports, China
Mobility Limitation, Wheelchairs
Observational Study on Changing the Quality of Life in Daily Life Activities After Clinical Approach Positioning the Wheelchair
Stemming from the common practice of attribution of the technical helps in the posture in Canada, the multidisciplinary approach of positioning develops in France for more than 10 years old.
- Trial name
- NCT02901444
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Sarcoma, Bone, Sarcoma, Soft Tissue
Deep Phenotyping Gait Deficits in Orthopedic Manifestations of Pediatric Cancer Patients
The goal of DEEPGAIT study is to determine how serious walking problems are for pediatric cancer patients who have had orthopedic surgery, how they change over time, and what can be done to help.
- Conditions
- Sarcoma, Bone, Sarcoma, Soft Tissue, Gait Disorder
- Trial name
- NCT07502885
- Testing
- Lab based 3D Gait Assessment, Wearable Inertial Sensors (In Lab and Remote), Functional Testing & Patient Reported Outcomes
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Accidental Falls, Gait Disorders
Virtual Reality for Walking and Balance in Older Adults
Falls are common in older adults due to aging-related problems with walking (gait) and balance. Virtual Reality (VR) is a new technology that creates interactive video game-like exercises.
- Conditions
- Accidental Falls, Gait Disorders, Neurologic Injury
- Trial name
- VR-GAIT (NCT07655882)
- Testing
- Virtual Reality Headset, Conventional Gait and Balance Training
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- University of Faisalabad
Mobility Limitation
Stepping-Up: Partnering With the Community to Prevent Early Mobility Decline
Preclinical mobility limitations (PCML) manifest early in the process of declining mobility, and are not typically identified or acted upon by clinicians.
- Trial name
- Stepping-Up (NCT04368949)
- Testing
- Stepping-Up, Telephone-Based Coaching Walking Program, Chair-Based Yoga Program
- Where
- Canada
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- McMaster University
Ictus, Gait Disorders, Neurologic
Percutaneous Ultrasound-guided Neuromodulation to Improve Gait Rehabilitation in Patients Who Have Suffered a Stroke.
The goal of this clinical trial is to learn if percutaneous ultrasound-guided neuromodulation (NMP-e) can improve gait rehabilitation in adults who have suffered a stroke.
- Trial name
- NCT07196878
- Testing
- Ultrasound-Guided Percutaneous Neuromodulation
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Alejandro Martín García
Mobility Limitation, Frailty
Assisted Ambulation to Improve Health Outcomes for Older Medical Inpatients
The investigator proposes to conduct a randomized trial of supervised ambulation delivered by mobility technician (MT) up to three times daily, including weekends, to hospitalized medical patients.
- Conditions
- Mobility Limitation, Frailty, Hospital Acquired Condition, Weakness, Muscle
- Trial name
- NCT05725928
- Testing
- Mobility technician
- Where
- 5 sites in United States
- Volunteers
- 3,000 people
- Sponsor
- The Cleveland Clinic
Aging Well, Walking, Difficulty
Heat Therapy, Functional Capacity, and Vascular Health in Older Adults
To test the hypothesis that home-based leg heat therapy improves functional capacity, vascular function, and exercise hyperemia in older adults.
- Conditions
- Aging Well, Walking, Difficulty, Hyperemia
- Trial name
- NCT05706181
- Testing
- Home-based leg heat therapy
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of North Texas Health Science Center
Peripheral Artery Disease, Peripheral Vascular Disease
Far Red Light to Improve Functioning in PAD
The LIGHT PAD Trial is a Phase II multi-centered randomized clinical trial to collect preliminary data to test whether daily far red light treatment of the lower extremities in people with PAD improves six-minute walk distance…
- Conditions
- Peripheral Artery Disease, Peripheral Vascular Disease, Aging, Walking, Difficulty
- Trial name
- LIGHT PAD (NCT06165016)
- Testing
- Far red light therapy
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Northwestern University
Cognitive Dysfunction, Mobility Limitation
Up-2 Study: Cognitively Engaging Walking Exercise and Neuromodulation to Enhance Brain Function in Older Adults
Declines in cognitive function and walking function are highly intertwined in older adults. A therapeutic approach that combines complex (cognitively engaging) aerobic walking exercise with non-invasive electrical brain…
- Conditions
- Cognitive Dysfunction, Mobility Limitation, Frail Elderly
- Trial name
- NCT05830942
- Testing
- Walking Exercise, Prefrontal Active tDCS
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Florida
Hiv, Fatigue
High-Intensity Exercise to Attenuate Limitations and Train Habits in Older Adults With HIV
This is a multi-site, randomized, single-blind (researchers), active treatment concurrent control trial with individuals aged 50-80 living with HIV who experience fatigue and live a sedentary lifestyle.
- Conditions
- Hiv, Fatigue, Mobility Limitation
- Trial name
- HEALTH (NCT04550676)
- Testing
- HIIT (intervention), CME (active control), Coaching
- Where
- 3 sites in United States
- Volunteers
- 118 people
- Sponsor
- University of Colorado, Denver
Parkinson Disease, Freezing of Gait
Use of CereGate Therapy for Freezing of Gait in PD
A Multi-Center, Controlled Study to Evaluate Use of CereGate Therapy to Reduce Freezing of Gait in Participants Diagnosed with Parkinson's Disease.
- Conditions
- Parkinson Disease, Freezing of Gait, Deep Brain Stimulation
- Trial name
- NCT05292794
- Testing
- CereGate Software; BSN cDBS Programmer; BSN Burst Programmer
- Where
- 7 sites in United States
- Volunteers
- 41 people
- Sponsor
- CereGate Inc.
Charcot-Marie-Tooth Disease, Type IA, Peripheral Neuropathy Hereditary
Physical Activity Level at Home in CMT1A Patients: Wearable Sensor Assessment
Charcot-Marie-Tooth disease type 1A (CMT1A) is the most common hereditary peripheral neuropathy, affecting approximately 26,000 patients in France.
- Conditions
- Charcot-Marie-Tooth Disease, Type IA, Peripheral Neuropathy Hereditary, Motor Activity, Walking, Difficulty
- Trial name
- CMT1A-HOME (NCT07591779)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Limoges
Joint Discomfort, Musculoskeletal Pain
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of resO™ Bone and Joint Support Postbiotic on Physical Function, Pain Interference, and Mobility in Adults With Joint Discomfort
This randomized, double-blind, placebo-controlled study evaluates the effects of resO™ Bone and Joint Support Postbiotic on physical function, pain interference, mobility, and recovery in adults aged 18-75 years experiencing…
- Conditions
- Joint Discomfort, Musculoskeletal Pain, Mobility Limitation
- Trial name
- RESO101 (NCT07602426)
- Testing
- Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Able Biolabs, LLC
Mobility Limitation, Overweight or Obesity
Functional Fitness for Overweight or Obese Adults With Mobility Disabilities
Over 64 million people in the U.S. have a permanent disability, with mobility-related disability (MRD) representing the most prevalent disability type (13.7%).
- Conditions
- Mobility Limitation, Overweight or Obesity, Physical Disability
- Trial name
- COBRE Pilot (NCT05880966)
- Testing
- Functional Fitness
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Kansas
Stroke, Spasticity
Effects of Low-level Laser Therapy on Spasticity and Gait Parameters in Chronic Stroke Patients With Spastic Plantar Flexors
Stroke is one of the leading causes of long-term disability worldwide. Many patients who survive a stroke experience muscle stiffness (called spasticity), especially in the ankle and foot muscles, which makes walking difficult…
- Conditions
- Stroke, Spasticity, Plantar Flexors
- Trial name
- LLLT-STROKE (NCT07273591)
- Testing
- Low Level Laser Therapy, conventional physical therapy
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Montiha Azeem
Stroke, Sarcopenia
Effects of Overground Robot-Assisted Gait Training on Stroke-Related Sarcopenia
This single-center randomized controlled trial evaluates the effects of combining overground robot-assisted gait training (o-RAGT) with recumbent cycling (RC) compared with RC alone in patients with subacute stroke at risk of…
- Conditions
- Stroke, Sarcopenia, Muscle Atrophy, Mobility Limitation
- Trial name
- oRAGT-PSS (NCT06910254)
- Testing
- Overground Robot-Assisted Gait Training (o-RAGT), Recumbent Bicycle Training
- Where
- South Korea
- Volunteers
- 53 people
- Sponsor
- Sahmyook University
Vision, Low, Mobility Limitation
Evaluating Stairway Designs for Individuals With Vision Impairment
The goal of this study is to learn if contrast frequency on step tread-edges influences foot clearance measures, a marker of fall risk, in older adults with and without visual impairments.
- Trial name
- NCT07337317
- Testing
- Frequency of contrast marking on stair steps
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The University of Alabama in Huntsville
Falls Prevention
Walk On! National Council on Aging Innovation Lab
This is a multi-site, one-arm type-2 hybrid-effectiveness implementation trial. The goal of this clinical trial is to learn if the Walk On! program helps prevent falls in older adults who have trouble moving around or feel…
- Trial name
- Walk On! NCOA (NCT07368907)
- Testing
- Walk On! Program
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Wake Forest University Health Sciences