Clinical trials: Limitation, Mobility
Aging
Oxidative Stress Links Aging, Activity, and Mobility Limitation
The purpose of this study is to understand why and how oxidative stress negatively impacts mobility in the elderly, and to determine whether antioxidant supplements can increase vascular health and mobility.
- Trial name
- NCT01177189
- Testing
- Vitamins C, E, and alpha lipoic acid
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Obesity
Increasing Physical Activity Among Overweight Women With Mobility Disabilities.
This study aims to increase physical activity among overweight African-American women with mobility limitations.
- Trial name
- PEP (NCT00164515)
- Testing
- Personalized exercise programme (PEP)
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Centers for Disease Control and Prevention
Children, Urologic Diseases
Emergence Agitation Between Sevoflurane and Desflurane in Pediatric
Sevoflurane is the volatile anesthetic agent of choice in pediatric surgery. Nevertheless, sevoflurane anesthesia had the high incidence of emergence delirium compared to halothane and isoflurane.Bortone L et al.reported…
- Conditions
- Children, Urologic Diseases, Ambulation Difficulty
- Trial name
- NCT01235143
- Testing
- Desflurane, Sevoflurane
- Where
- Thailand
- Volunteers
- 136 people
- Sponsor
- Prince of Songkla University
Interstitial Lung Disease
The Impact of Pulmonary Rehabilitation in Interstitial Lung Disease
The purpose of this study is to determine if pulmonary rehabilitation has any effect on breathlessness, quality of life, physical function and depression in persons with interstitial lung disease.
- Trial name
- PR-ILD (NCT01055730)
- Testing
- Pulmonary rehabilitation
- Where
- 6 sites in United States, Canada
- Volunteers
- 54 people
- Sponsor
- University of California, San Francisco
Vestibular Diseases, Gait Disorders
Safety and Efficacy Study of BrainPort® Balance Device in Peripheral Vestibular Dysfunction.
The purpose of this study is to assess the safety and efficacy of the BrainPort balance device in improving balance and gait as measured by clinically accepted standardized balance assessments in subjects with peripheral…
- Trial name
- NCT00768378
- Testing
- Training with the BrainPort balance device
- Where
- 17 sites in United States
- Volunteers
- 147 people
- Sponsor
- Wicab
Peripheral Artery Disease, Peripheral Vascular Disease
ENhancing Exercise With LIGHT to Improve Functioning in PAD
The ENLIGHTEN PAD Trial will collect preliminary data to test whether daily 660 nm light treatment of the lower extremities immediately before home-based walking exercise sessions improves six-minute walk distance at 4-month…
- Conditions
- Peripheral Artery Disease, Peripheral Vascular Disease, Aging, Walking, Difficulty
- Trial name
- ENLIGHTEN PAD (NCT06399900)
- Testing
- Far red light therapy, Home-based walking exercise
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Northwestern University
Mobility Limitation, Fall Injury
Home-based HIFST for Older Adults to Prevent Functional Decline
After an injury, an older adult may experience changes to how they complete their daily activities and participate in physical activity.
- Conditions
- Mobility Limitation, Fall Injury, Slip and Fall
- Trial name
- NCT05266911
- Testing
- high-intensity functional strength training, Lower extremity stretching
- Where
- 2 sites in Canada
- Volunteers
- 24 people
- Sponsor
- McMaster University
Niemann-Pick Disease, Type C
VTS-270 to Treat Niemann-Pick Type C1 (NPC1) Disease
Due to different study designs, the sponsor separated Part C into a separate registration (NCT04958642), leaving Parts A/B here in NCT02534844.
- Trial name
- NCT02534844
- Testing
- Parts A/B: Adrabetadex
- Where
- 29 sites in United States, Australia and 7 more
- Volunteers
- 56 people
- Sponsor
- Mandos LLC
Frailty, Sarcopenia
Resistance-Based Multicomponent Training Plus Nutrition Supplementation for Intrinsic Capacity and Disability Risk in Chinese Rural Older Adults
This study is a five-arm, parallel-group, assessor-blinded randomized controlled trial designed to evaluate the effects of resistance-dominant multicomponent training combined with nutritional supplementation on intrinsic…
- Conditions
- Frailty, Sarcopenia, Mobility Limitation, Nutritional Risk
- Trial name
- NCT07660653
- Testing
- Routine Health Education, Leucine-Enriched Whey Protein and Vitamin D Supplementation, Progressive Resistance Training
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Capital University of Physical Education and Sports, China
Multiple Sclerosis
Effects of Targeted Lower Extremity Joint Training on Multiple Sclerosis (MS) Gait Abnormalities
This study is being done to test the possible benefits of task-specific focused ankle training using the Ankle-Bot on subjects with Multiple Sclerosis who have "foot-drop." The study also compares the effectiveness of…
- Trial name
- NCT00906737
- Testing
- Ankle-bot, Conventional focused ankle therapy
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Mount Sinai Rehabilitation Hospital
Rehabilitation, Aging Problems
Plantar Fasciitis Management on Postural Control
Foot pain is common in the general population. Plantar fasciopathy may affect 7% of the population at some time in their lives, but the incidence increases with age.
- Conditions
- Rehabilitation, Aging Problems, Foot Diseases, Mobility Limitation
- Trial name
- NCT06172517
- Testing
- Orthosis intervention
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Université du Québec à Chicoutimi
Mobility Limitation, Sleep Quality
Use Modular Medical Equipment Vehicle in Mobilization of Patient With Chest Tube
in this study, it was aimed to examine the effect of the modular carrying system on the outcomes of care in the mobilization of patients with a chest tube.
- Conditions
- Mobility Limitation, Sleep Quality, Pain, Comfort
- Trial name
- NCT05081856
- Testing
- mobilization with moduler medical equipment carring vehicle
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people
- Sponsor
- Istanbul Medipol University Hospital
Chronic Obstructive Pulmonary Disease (COPD)
Effects of Blood Flow Restriction Rehabilitation on Functional Mobility and Balance Among Chronic Obstructive Pulmonary Disease Patients.
Background: Chronic obstructive pulmonary disease (COPD) is a common lung disease causing restricted airflow and breathing problems. It is sometimes called emphysema or chronic bronchitis.
- Trial name
- NCT07805330
- Testing
- Resistance Exercise without tourniquet, Blood flow restriction resistance exercise
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Rashid Latif Medical College
Idiopathic Normal Pressure Hydrocephalus (INPH)
Change in Cognition and Frailty After Shunt Surgery in Idiopathic Normal Pressure Hydrocephalus (iNPH)
The goal of this observational study is to describe changes in cognitive profile and frailty from pre shunt to one year after the shunt surgery and to identify clinical predictors of an improvement in terms of cognition and…
- Trial name
- NCT07642726
- Testing
- Ventriculoperitoneal shunt
- Where
- Norway
- Volunteers
- 276 people
- Sponsor
- Oslo University Hospital
Hemiparesis/Hemiplegia (One Sided Weakness/Paralysis), Gait Disorder
Isokinetic Strength Training in Hemiparetic Patient With Knee Extension Thrust
The purpose of this study is to assess the impact of an isokinetic strength training of knee flexor and extensor muscles on walking performance in hemiparetic patients with knee extension thrust.
- Trial name
- ISOWALK (NCT05887440)
- Testing
- isokinetic strength training of knee extensor and flexor muscles
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Rennes University Hospital
Joint Discomfort, Musculoskeletal Pain
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of resO™ Bone and Joint Support Postbiotic on Physical Function, Pain Interference, and Mobility in Adults With Joint Discomfort
This randomized, double-blind, placebo-controlled study evaluates the effects of resO™ Bone and Joint Support Postbiotic on physical function, pain interference, mobility, and recovery in adults aged 18-75 years experiencing…
- Conditions
- Joint Discomfort, Musculoskeletal Pain, Mobility Limitation
- Trial name
- RESO101 (NCT07602426)
- Testing
- Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Able Biolabs, LLC
Low Vision, Orientation
SmartHMD for Improved Mobility
The National Eye Institute estimated about 3 million people over age 40 in the US had low vision in 2010 and projects an increase to nearly 5 million in 2030 and 9 million in 2050.
- Conditions
- Low Vision, Orientation, Mobility Limitation, Navigation, Spatial
- Trial name
- NCT03781583
- Testing
- SmartHMD version 1, SmartHMD version 2, SmartHMD version 3
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- James Weiland
Stroke, Difficulty Walking
Body Weight Supported Treadmill Training vs. Overground Walking Training in Persons With Chronic Stroke
The purpose of this study is to compare two different walking training programs for persons with chronic stroke.
- Trial name
- NCT01180738
- Testing
- Body weight supported treadmill training, Overground walking training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stephanie Miller
Menopause, Gait, Unsteady
Effects of Strength Training on the Gait and Pelvic Floor in Menopausal Women
The overall objective will be to observe whether a strength and balance training intervention produces significant changes in the analysis of double stance phase movement during gait, the analysis of coxofemoral, tibial and…
- Conditions
- Menopause, Gait, Unsteady, Pelvic Floor Disorders
- Trial name
- NCT07824947
- Testing
- Strength training
- Where
- Spain
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Hiv, Fatigue
High-Intensity Exercise to Attenuate Limitations and Train Habits in Older Adults With HIV
This is a multi-site, randomized, single-blind (researchers), active treatment concurrent control trial with individuals aged 50-80 living with HIV who experience fatigue and live a sedentary lifestyle.
- Conditions
- Hiv, Fatigue, Mobility Limitation
- Trial name
- HEALTH (NCT04550676)
- Testing
- HIIT (intervention), CME (active control), Coaching
- Where
- 3 sites in United States
- Volunteers
- 118 people
- Sponsor
- University of Colorado, Denver