Clinical trials: Lip
Lip Augmentation
Postmarket Study of JUVÉDERM VOLBELLA™ With Lidocaine in the Lips
A prospective, multicenter postmarket study of the use of JUVÉDERM VOLBELLA™ with Lidocaine in the lips.
- Trial name
- NCT01629134
- Testing
- Crosslinked hyaluronic acid gel
- Where
- Germany
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Allergan Medical
Lip Augmentation
Clinical Investigation of YVOIRE Y-Solution 360 for Lip Augmentation in China
To evaluate the effectiveness and safety of the investigational medical device, injected into the lips.
- Trial name
- NCT05314504
- Testing
- YVOIRE Y-Solution 360
- Where
- China
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- LG Chem
Lip Volume Enhancement, Lip Augmentation
A Post-Marketing Study of Alexa Medium for Сorrection of the Lips Volume Loss
This post-marketing, prospective, multicentre, single-arm, open-label clinical investigation aimed to evaluate the safety, tolerability, and effectiveness of the injectable medical device Alexa Medium (based on cross-linked…
- Conditions
- Lip Volume Enhancement, Lip Augmentation, Aesthetic
- Trial name
- AL-MED (NCT06961305)
- Testing
- Cross-linked Hyaluronic Acid Gel
- Where
- 4 sites in Poland, Ukraine
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Institute Hyalual GmbH
Skin Quality, Lips Quality
Evaluation of the Effects of an Oral Supplementation Containing Hyaluronic Acid
This is a single center, double-blind, randomized, placebo-controlled study, performed on two parallel groups. A total of 130 adult female subjects meeting specific inclusion/exclusion criteria will be included in order to have…
- Conditions
- Skin Quality, Lips Quality, Persistence of the Effect
- Trial name
- NCT06774742
- Testing
- HAFS Supplementation
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- TS Biotech - Shandong Tiansheng Biotechnology Co., Ltd
Dermal Filler
Safety and Efficacy of the HA-based Dermal Fillers HYAcorp Lips and Face
Purpose of this study is the demonstration of safety and efficacy of the dermal fillers HYAcorp Lips and HYAcorp Face for restoration of the facial volume and contour.
- Trial name
- PMCF_HYAcorp (NCT04546516)
- Testing
- HYAcorp Lips and HYAcorp Face
- Where
- 2 sites in Germany
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- BioSCIENCE GmbH
Lip Augmentation
A Multicenter, Open-Label Retreatment Study of the Safety and Effectiveness of PN40082 for Lip Augmentation
To evaluate the safety and efficacy of retreatment with PN40082 for lip augmentation.
- Trial name
- NCT04029519
- Testing
- PN40082
- Where
- 6 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Prollenium Medical Technologies Inc.
Sunscreening Agents
Clinical Study to Evaluate the Efficacy of an Over-the-counter (OTC) Sunscreen Lip Balm
The purpose of this study is to evaluate the 8-hour moisturization efficacy of OTC sunscreen lip balm after a single treatment application.
- Trial name
- NCT05082376
- Testing
- CLM Original
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- HALEON
Lip Augmentation
A Study to Evaluate the Safety and Performance of Dr Korman Laboratories' Hyaluronic Acid Filler 20 mg/mL With Lidocaine for Lip Augmentation
This study will assess the safety and effectiveness of a dermal filler called DKL crosslinked hyaluronic acid 20 mg/mL with lidocaine 0.3% when injected into the lips of healthy men and women who want to have fuller lips.
- Trial name
- NCT07204691
- Testing
- DKL crosslinked sodium hyaluronate 20 mg/mL + Lidocaine 0.3% dermal filler
- Where
- 2 sites in Sweden
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Dr. Korman Laboratories Ltd.
Correction of Nasolabial Folds and Lip Augmentation
PREVELLE Shape (CX002) Dermal Filler Protocol
The purpose of this study was to assess PREVELLE Shape (CX002), with respect to safety and efficacy for one year following treatment, for correction of facial nasolabial folds and when applied as an intradermal implant for lip…
- Trial name
- NCT00764257
- Testing
- PREVELLE Shape, Restylane
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mentor Worldwide, LLC
Lip Augmentation
Safety and Effectiveness of PN40082 for Lip Augmentation
To compare the safety and efficacy profile of PN40082 versus Restylane Silk Injectable Gel with 0.3% lidocaine (Restylane Silk) for lip augmentation in approximately 158 subjects.
- Trial name
- NCT04032977
- Testing
- PN40082, Restylane Silk
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Prollenium Medical Technologies Inc.
Lips Enhancement, Nasolabial Fold Correction
Evaluation of the Safety and Performance of an Injectable Hyaluronic Acid Filler
Evaluation of the safety and performance of the investigational device in its three concentrations for cheek and lips augmentation and correction of the nasolabial folds, assuming that the performance of the product will be…
- Conditions
- Lips Enhancement, Nasolabial Fold Correction, Midface Volume Deficit
- Trial name
- NCT04971876
- Testing
- HLR-1, HLR-2, HLR-3
- Where
- 3 sites in Germany, Poland
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Hallura Ltd.
Abnormal Lip
Study to Evaluate the Effectiveness, Safety and Long Term Safety of Saypha® FILLER Lidocaine for Lip Augmentation
This is a prospective, open-label, multicentre, randomized study conducted to evaluate the effectiveness, safety and long-term safety of Saypha® FILLER Lidocaine for lip augmentation.
- Trial name
- SayLip (NCT04917588)
- Testing
- Saypha® FILLER Lidocaine (HQ), Saypha® FILLER Lidocaine (C1)
- Where
- 3 sites in Austria
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Croma-Pharma GmbH
Herpes Labialis
Bioequivalence Study of Aciclovir 5% Cream in Japanese Healthy Volunteers
This study is designed to show bioequivalence between Current and New formulation of Aciclovir cream 5% in keratin layer of the epidermis in Japanese Subjects
- Trial name
- NCT00711776
- Testing
- New formulation, Current formulation
- Where
- Japan
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Lip Augmentation
Study to Evaluate Satisfaction After Treatment With Kysse
Open-label, phase IV, post-marketing study to evaluate aesthetic improvement and satisfaction after treatment with Kysse.
- Trial name
- NCT03967444
- Testing
- Hyaluronic acid
- Where
- 2 sites in Canada
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Recurrent Herpes Simplex Labialis
A Multicenter Study of NB-001 in the Treatment of Recurrent Herpes Labialis
Demonstrate the safety and efficacy of NB-001 in subjects with recurrent herpes labialis (RHL).
- Trial name
- SHaRCS (NCT01321359)
- Testing
- Vehicle versus NB-001
- Where
- 35 sites in United States
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- NanoBio Corporation
Esthetics
Effectiveness and Safety of STYLAGE® M Lidocaïne for Lips' Volume Augmentation and/or Redefinition of the Outline of the Lips (SMILE)
STYLAGE® M Lidocaine is a hyaluronic acid injectable gel CE (conformité européenne)-marketed since 2009 . It is indicated for the outline of the lips and/or for lips augmentation in lips mucosa.
- Trial name
- SMILE (NCT04813614)
- Testing
- STYLAGE M Lidocaine, Active control group
- Where
- 2 sites in France, Poland
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Laboratoires Vivacy
Relationship Between the Exposure of Glucocorticoids During Pregnancy and Orofacial Cleft Development
A Study to Learn More About the Relationship Between the Development of a Gap in the Upper Lip (Cleft Lip) or in the Roof of the Mouth (Cleft Palate) in Newborns and the Use of Glucocorticoids by the Mother During Pregnancy: a Meta-analysis
Glucocorticoids are drugs that have many effects on body metabolism, raise sugar level in the blood, and reduce inflammation. By applying a statistical technique for combining the findings from a systematic literature review…
- Trial name
- NCT03788863
- Testing
- Diflucortolone valerate (BAY866146)
- Where
- Germany
- Volunteers
- 99,999 people, healthy volunteers welcome
- Sponsor
- LEO Pharma
Recurrent Herpes Labialis
A Multicenter Study of NB-001 in the Treatment of Recurrent Herpes Labialis (SHaRCS)
The purpose of this study is to demonstrate the safety and efficacy of NB-001 in subjects with recurrent herpes labialis (RHL).
- Trial name
- SHaRCS (NCT01324466)
- Testing
- NB-001, Vehicle
- Where
- 35 sites in United States
- Volunteers
- 847 people, healthy volunteers welcome
- Sponsor
- NanoBio Corporation
COPD
The Effect of Volitional Pursed-lips Breathing
Simulation of pursed-lips breathing by defined stenoses in pulmonary function diagnostics to quantify the effect of the pursed-lips breathing
- Trial name
- PLB (NCT04663698)
- Testing
- Baseline, MESH-Resistor 5, MESH-Resistor 10
- Where
- Germany
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Karl Josef Franke, PD DR med
Lip Enhancement
Safety and Effectiveness of JUVÉDERM® VOLBELLA® With Lidocaine for Lip Enhancement in Chinese Adults
This study will evaluate the safety and effectiveness of VOLBELLA with Lidocaine injectable gel in Chinese adults seeking lip enhancement.
- Trial name
- NCT03519204
- Testing
- JUVÉDERM® VOLBELLA® XC with Lidocaine, No-treatment Control
- Where
- 5 sites in China
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Allergan