Clinical trials: Lipemia
Cardiovascular Diseases, Lipid Testing
Promoting Cholesterol Screening
Cholesterol screening is an important prerequisite for cardiovascular disease (CVD) risk assessment. Cholesterol screening is recommended by the United States Preventive Services Task Force (USPSTF).
- Conditions
- Cardiovascular Diseases, Lipid Testing, Primary Prevention of Cardiovascular Disease
- Trial name
- NCT01930149
- Testing
- Mailed patient outreach intervention
- Where
- 3 sites in United States
- Volunteers
- 480 people
- Sponsor
- Northwestern University
Hypercholesterolemia, Dyslipidaemias
An Exploratory Study To Look At The Effect Of Two Investigational Drugs On Body Fat And Inflammation
The investigational drugs administered in this study activate proteins called PPARs. Data in the scientific literature on PPARs, as well as animal data and early clinical data generated by GSK with these drugs, suggest that…
- Conditions
- Hypercholesterolemia, Dyslipidaemias, Obesity
- Trial name
- NCT00388180
- Testing
- GW501516, GW590735
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Hypercholesterolemia, Familial
Screening Protocol for a Gene Therapy Trial in Subjects With Homozygous Familial Hypercholesterolemia
The purpose of this protocol is to identify and screen potential candidates for future enrollment in a gene therapy clinical trial for HoFH.
- Trial name
- NCT03018678
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Pennsylvania
Spinal Cord Injury
Coronary Artery Calcification Score and Risk Factors for Coronary Artery Disease in Persons With Spinal Cord Injury
Although conventional risk factors for coronary heart disease (CHD) have been identified and routinely used to determine risk for CHD in the general population, a systematic approach to determine population-specific risk for CHD…
- Trial name
- CAC (NCT02007226)
- Where
- 2 sites in United States
- Volunteers
- 83 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Primary Dyslipidemia, Mixed Dyslipidemia
Prevail-Us: A Study Of Pitavastatin 4 mg Vs. Pravastatin 40 mg In Patients With Primary Hyperlipidemia Or Mixed Dyslipidemia
Randomized, double-blind, double-dummy, 12-week, active-controlled study of pitavastatin 4 mg daily(QD) vs. pravastatin 40 mg daily(QD) in subjects with primary hyperlipidemia or mixed dyslipidemia.
- Trial name
- PREVAIL-US (NCT01256476)
- Testing
- pitavastatin, pravastatin
- Where
- 44 sites in United States
- Volunteers
- 328 people
- Sponsor
- Kowa Research Institute, Inc.
Metabolic Syndrome
To Compare the Effects of Herbal Medicines With Traditional Allopathic Medicines in Cases of Patients With Metabolic Syndrome
Metabolic syndrome is an important global public health problem and comprises a group of complex risk factors, including obesity, dyslipidemia, hyperglycemia, and hypertension.
- Trial name
- NCT06515652
- Testing
- rosuvastatin, METFORMIN, Sitagliptin, Telmisartan, Cinnamon. garlic, Ginger, Methi dana, Arjun
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Hamdard University
Heterozygous Familial Hypercholesterolemia, Premature Coronary Heart Disease
A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease
VT-10201 is an Open-label, Phase 1b, Single-ascending Dose Study That Will Evaluate the Safety of VERVE-102 Administered to Patients With Heterozygous Familial Hypercholesterolemia (HeFH) or Premature Coronary Artery Disease…
- Trial name
- NCT06164730
- Testing
- VERVE-102
- Where
- 27 sites in United States, Australia and 4 more
- Volunteers
- 85 people
- Sponsor
- Verve Therapeutics, Inc.
Mammography, Estrogen
Zoladex Plus Tamoxifen in Breast Cancer
The purpose of this study is to compare Zoladex plus tamoxifen with tamoxifen alone as adjuvant hormonal therapy in pre- or perimenopausal women with early-stage breast cancer in terms of breast density, estrogen levels…
- Conditions
- Mammography, Estrogen, Lipemia, Endometrium
- Trial name
- NCT00827307
- Testing
- tamoxifen, Goserelin
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhejiang Cancer Hospital
Hypercholesterolemia
Effect of LDL-apheresis on PTX3 Plasma Levels in Hypercholesterolemic Patients
Inflammation plays a major role in atherosclerosis. Pentraxin 3 (PTX3) a multifunctional pattern-recognition protein, is expressed in many tissues/cells, including innate immunity cells, endothelium and atherosclerotic plaques.
- Trial name
- NCT01678521
- Testing
- LDL-apheresis
- Where
- Italy
- Volunteers
- 12 people
- Sponsor
- Universita di Verona
Hyperlipidemia, Cardiovascular Diseases
Lipoprotein Turnover on Low- and High-MUFA Portfolio Diets
Low and very low carbohydrate diets, such as the Atkins' Diet, have recently gained attention for their potential health benefits from weight loss and have gained some scientific support from a growing number of studies.
- Conditions
- Hyperlipidemia, Cardiovascular Diseases, Diet Therapy
- Trial name
- NCT00430430
- Testing
- High MUFA dietary portfolio, Low MUFA dietary portfolio
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Type 2 Diabetes, Hyperlipidemia
The Effect of Green Tea Extract on Type 2 Diabetes With Hyperlipidemia
The aim of the study is to examine whether the extract of green tea is effective on type 2 diabetes and hyperlipidemia.
- Trial name
- NCT01360567
- Testing
- Green tea extract
- Where
- 2 sites in Taiwan
- Volunteers
- 102 people
- Sponsor
- Taipei City Hospital
Hyperlipemia, Coronary Heart Disease
Effect of Rosuvastatin Therapy on HDL2 Level
In many large trials, reducing low density lipoprotein (LDL) levels with rosuvastatin decreased the incidence of major cardiovascular events,but little attention to the effects of rosuvastatin on HDL level,especially on HDL…
- Trial name
- NCT02593487
- Testing
- Rosuvastatin 10mg/d group, Rosuvastatin 20mg/d group
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Post Coronary Artery Bypass Grafting, Hypertension
"Smart Family Doctor" Assisted Comprehensive Management of Secondary Prevention Among Post Coronary Artery Bypass Graft Patients or Post Percutaneous Coronary Intervention Patients
This study aims to evaluate the effect of an AI-assisted "Smart family doctor" digital health management tool on improving the control rates of hypertension, diabetes, and dyslipidemia in post-CABG (coronary artery bypass…
- Conditions
- Post Coronary Artery Bypass Grafting, Hypertension, Diabetes Mellitus, Hyperlipidemia
- Trial name
- SMART (NCT06615609)
- Testing
- Smart family doctor, Health manager
- Where
- China
- Volunteers
- 536 people
- Sponsor
- China National Center for Cardiovascular Diseases
Hypertension With Hyperlipidemia
Study to Evaluate the Safety and Efficacy of CJ-30060 in Hypertensive Patients With Hyperlipidemia
To evaluate the safety and efficacy of CJ-30060 compared with amlodipine/valsartan combination therapy and valsartan/rosuvastatin combination therapy in hypertensive patients with hyperlipidemia
- Trial name
- NCT03536598
- Testing
- Amlodipine 10 mg + Valsartan 160 mg + Rosuvastatin 20 mg, Amlodipine 10 mg + Valsartan 160 mg, Valsartan 160 mg + Rosuvastatin 20 mg
- Volunteers
- 203 people
- Sponsor
- HK inno.N Corporation
Hypertension With Hyperlipidemia
Efficacy/Safety of Telmisartan/Amlodipine/Rosuvastatin in Hypertensive Patients With Hyperlipidemia
A Randomized, Double-blind, Multi-center Phase III Clinical Trial to Evaluate the Efficacy and Safety of Telmisartan/Amlodipine and Rosuvastatin Co-administration in Hypertensive Patients with Hyperlipidemia
- Trial name
- NCT03566316
- Testing
- Telmisartan/Amlodipine, Rosuvastatin, Telmisartan
- Where
- South Korea
- Volunteers
- 134 people
- Sponsor
- IlDong Pharmaceutical Co Ltd
Diabetes Mellitus Type 2, Hypercholesterolemia
Effect of Ezetimibe or Simvastatin or Both on Low Densitiy Lipoprotein -Subfractions in Patients With Type 2 Diabetes
It is of interest how ezetimibe alone or in combination with statin may influence atherogenic dense Low Density Lipoprotein (dLDL) in patients with type 2 diabetes mellitus.
- Trial name
- EZE (NCT01384058)
- Testing
- ezetimibe, simvastatin, Ezetimibe 10/Simvastatin 20
- Where
- 2 sites in Germany
- Volunteers
- 41 people
- Sponsor
- University Hospital Freiburg
Hypercholesterolemia
Probiotic BIO-25 as a Supplement to Statins for the Treatment of Hypercholesterolemia
The primary objective is to examine whether probiotics given to hypercholesterolemic patients treated with statins, would further decrease LDL-Cholesterol levels.
- Trial name
- NCT01849185
- Testing
- Food supplement
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Meir Medical Center
Stress, Hypercholesterolemia
Effects of Romantic Affection on Blood Chemistry and Immune Parameters
This trial tests the hypothesis that increasing nonverbal affection in romantic relationships will improve blood lipid parameters (total cholesterol, high and low density lipoproteins, triglycerides), blood glucose, and immune…
- Trial name
- NCT00482404
- Testing
- Romantic kissing
- Volunteers
- healthy volunteers welcome
- Sponsor
- Arizona State University
Hyperlipidemia, Glucose Metabolism Disorders
The Effect of Hypocol® on Lipids in Subjects With Mild Hypercholesterolemia and Mildly Elevated Blood Glucose
The purpose of this study is to determine to what degree Hypocol® (Red Yeast Rice) may lower low density lipoprotein (LDL)-cholesterol in a European population.
- Trial name
- NCT00114855
- Testing
- HYPOCOL®
- Where
- Norway
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Hypercholesterolemia
Study to Evaluate the Safety, PK, and Pharmacodynamics of LIB003
Randomized, double-blind, placebo-controlled, single ascending dose study in nine (9) separate and sequential dose cohorts (7 SC and 2 IV cohorts) to assess the safety and tolerability, pharmacokinetics and pharmacodynamics of…
- Trial name
- LIB003SAD (NCT03545438)
- Testing
- LIB003
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- LIB Therapeutics LLC
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