Clinical trials: Lipemia
Hypertension, Hyperlipidemias
DP-R212 Pharmacokinetic Study
An open-label, multiple-dose study to evaluate the pharmacokinetic drug-drug interaction of amlodipine and rosuvastatin in healthy adult male subjects.
- Trial name
- NCT02789475
- Testing
- Amlodipine, Rosuvastatin
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Alvogen Korea
Hypertriglyceridemia
Fat Tolerance From Lipid Emulsion Infusion Packaged in Glass or Plastic
This will be a prospective, randomized trial to determine if differences exist in the tolerance of lipid injectable emulsions in the neonatal intensive care unit (NICU).
- Trial name
- NCT00278928
- Testing
- Liposyn III 20% (lipid infusion), Intralipid 20% (lipid infusion)
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Beth Israel Deaconess Medical Center
Hypertriglyceridemia
Evaluation of the Efficacy of Phospholipid-Bound Omega-3 Versus Omega-3 Alone in Patients With Hypertriglyceridemia: A Randomized Clinical Trial
Hypertriglyceridemia is a significant risk factor for cardiovascular diseases. Omega-3 fatty acids have been shown to reduce triglyceride levels, and their combination with phospholipids could offer additional benefits in…
- Trial name
- OMEGA-PHYT (NCT06749028)
- Testing
- Intervention Arm: Omega-3 + Phospholipids., Comparator Arm: Omega-3 alone.
- Where
- Colombia
- Volunteers
- 44 people
- Sponsor
- Fundación del Caribe para la Investigación Biomédica
Hyperlipidemia, Coronary Artery Disease
Rosuvastatin Effect on Reducing Coronary Atherosclerosis Plaques Volume
This multicentre, open-label, single-arm Study is to evaluate the effect of Rosuvastatin 20 mg 76 weeks on coronary atherosclerosis plaque versus baseline in Chinese coronary heart disease (CHD) patients with hyperlipidemia by…
- Trial name
- REDUCT (NCT01382277)
- Testing
- Rosuvastatin
- Where
- 2 sites in China
- Volunteers
- 600 people
- Sponsor
- Peking University First Hospital
Hypertension, Metabolic Syndrome
Regulation of Inflammatory Parameters by Telmisartan in Hypertensive Patients
A number of studies have shown that certain blood-pressure medications such as ACE-inhibitors and angiotensin-II-receptor blockers (ARB) can reduce the incidence of diabetes mellitus type 2.
- Conditions
- Hypertension, Metabolic Syndrome, Hypertriglyceridemia
- Trial name
- METATEL (NCT00560430)
- Testing
- telmisartan
- Where
- 2 sites in Germany
- Volunteers
- 56 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Hypercholesterolemia
To Evaluate the Lipid-Lowering Efficacy and Safety of Simvastatin 40 Mg Tablet In Patients With Hypercholesterolemia (0733-264)
To collect lipid-lowering response data with the use of simvastatin 40 mg tablet in patients with hypercholesterolemia.
- Trial name
- NCT00398294
- Testing
- MK0733, simvastatin / Duration of Treatment: 12 Weeks
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Organon and Co
Dyslipidemias, Hypertriglyceridemia
Effects of Phytoestrogen From Pueraria Mirifica in Improvement of Serum Lipid Parameters in Postmenopausal Women
The goal of this clinical trial is to learn about the effects of phytoestrogen from Pueraria Mirifica in improvement of serum lipid parameters.
- Conditions
- Dyslipidemias, Hypertriglyceridemia, Hypercholesterolemia, Hyper-LDL-cholesterolemia
- Trial name
- NCT06220266
- Testing
- Phytoestrogen, Diet control & life style modification
- Where
- Thailand
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Dhurakij Pundit University
Hyperlipidemia
Study on the Sex-specific, Lipid- and Lipoprotein-lowering Effects of Berberine
The goal of this clinical trial is to learn if berberine works to affect lipids and lipoproteins in Chinese females aged 20 to 65 years with hyperlipidaemia.
- Trial name
- NCT06782646
- Testing
- Berberine
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Adverse Effects
Method of Fish Oil Administration on Patient Compliance
Many patients complain of fishy breath, upset stomach, or heartburn when taking the recommended amount of fish oil. A common recommendation made by pharmacists is to freeze the fish oil capsules to help decrease adverse…
- Trial name
- NCT01471366
- Testing
- Frozen capsule, Capsule with food, Capsule without food
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Mississippi, Oxford
Hyperlipidemia, Cardiovascular Diseases
Lipoprotein Turnover on Low- and High-MUFA Portfolio Diets
Low and very low carbohydrate diets, such as the Atkins' Diet, have recently gained attention for their potential health benefits from weight loss and have gained some scientific support from a growing number of studies.
- Conditions
- Hyperlipidemia, Cardiovascular Diseases, Diet Therapy
- Trial name
- NCT00430430
- Testing
- High MUFA dietary portfolio, Low MUFA dietary portfolio
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Cardiovascular Diseases, Atherosclerosis
Lipid Research Clinics Population Studies
To conduct epidemiologic surveys of the distribution, causes, and consequences of the dyslipoproteinemias. The Population Studies include the Prevalence Study, the Family Study, and the Mortality Follow-up Study and shared the…
- Conditions
- Cardiovascular Diseases, Atherosclerosis, Coronary Disease, Heart Diseases
- Trial name
- NCT00005128
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Obesity
A Study on Efficacy and Safety of Topiramate in Maintaining Weight Loss in Obese Patients Following an Intensive, Non-Pharmacologic Weight Loss Program
The purpose of this study is to compare the efficacy and safety of topiramate 96mg and 192mg daily) with placebo in the treatment of obesity following an intensive non-pharmacologic weight loss program.
- Trial name
- NCT00236600
- Testing
- topiramate
- Volunteers
- 561 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Hypercholesterolemia
Bioequivalence Study Comparing A New 10 Mg Atorvastatin Tablet To A 10 Mg Atorvastatin Commercial Tablet
To determine whether new 10 mg atorvastatin tablets are bioequivalent to 10 mg commercial atorvastatin tablets (Lipitor®).
- Trial name
- NCT00917579
- Testing
- Atorvastatin
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Hypercholesterolemia
A Non-interventional Implementation Study to Evaluate Treatment With Inclisiran (Leqvio®) and Other Lipid Lowering Treatments in a Real-world Setting
This was a multicenter, non-randomized, non-interventional three-cohort study with prospective collection of primary data of treatment with newly initiated oral lipid lowering treatment on top of a statin (Oral LLT cohort), newly…
- Trial name
- NCT05362903
- Testing
- Inclisiran
- Where
- 121 sites in Germany
- Volunteers
- 1,868 people
- Sponsor
- Novartis Pharmaceuticals
Hyperlipidemia, Healthy
Effects of Omega-3 Fatty Acids on the Human Gene Expression
The aim of this study is to investigate the effects of short- and long-term intervention with EPA and DHA-rich fish oil on gene expression profiles in healthy and hyperlipidemic males.
- Trial name
- NCT01089231
- Testing
- Fish oil
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gottfried Wilhelm Leibniz Universität Hannover
Hyperlipidemia, Atrial Fibrillation
Impact of MayoExpertAdvisor on Provider Adherence
This study evaluates the efficacy of MayoExpertAdvisor (MEA), a knowledge delivery tool, to improve adherence to best practices for patients with hyperlipidemia, atrial fibrillation and heart failure.
- Conditions
- Hyperlipidemia, Atrial Fibrillation, Heart Failure
- Trial name
- MEA Research (NCT02742545)
- Testing
- MayoExpertAdvisor
- Where
- United States
- Volunteers
- 2,248 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Overweight; Hyperlipidemia
Efficacy and Safety of Fermented Barley on Decrement of Body Fat in Obese Subjects
Barley, like oats, is a rich source of the soluble fibre β-glucan, which has been shown to significantly lower LDL-cholesterol (LDL-C). However, barley foods have been less widely studied.
- Trial name
- NCT01402128
- Testing
- Barley beta-glucan(3.0g)
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Hyperlipidemia
Studies of Apolipoprotein Genotyping on the Drug Treatment of Hyperlipidemic Patients
Cardiovascular-related diseases have been the majorities of the leading ten causes of death in Taiwan. Atherosclerotic cardiovascular diseases are multifactorial. Some non-modifiable risk factors (e.g.
- Trial name
- NCT00451464
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Familial Hypercholesterolemia - Heterozygous
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
This is a pivotal phase III study designed to evaluate safety, tolerability, and efficacy of inclisiran in children (aged 6 to <12 years) with heterozygous familial hypercholesterolemia (HeFH) and elevated low density lipoprotein…
- Trial name
- ORION-20 (NCT06597019)
- Testing
- Inclisiran
- Where
- 66 sites in United States, Argentina and 21 more
- Volunteers
- 60 people
- Sponsor
- Novartis Pharmaceuticals
Otherwise Healthy Individuals With Systolic Blood Pressure (SBP) From 110 to 139 mmHg and Low-density Lipoprotein Cholesterol (LDL-C) ≥ 100 mg/dL
A Study to Evaluate COR-2003 as Monotherapy and Co-Administered With COR-1004 in Adult Volunteers
This clinical trial has two parts. In Part A, the goal is to learn about the safety and tolerability of COR-2003 when it is given alone.
- Trial name
- NCT07858019
- Testing
- COR-2003, COR-1004 + COR-2003
- Where
- 2 sites in Australia, New Zealand
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Corsera Health
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