Clinical trials: Lipemia
Hyperlipidemia
Standard Process 21 Day Purification Program Project
To determine the effects of a commercially available dietary modification plus nutritional supplement regimen, the Standard Process 21 day Purification Program (SPPP), on serum lipids, C-reactive protein (CRP), homocysteine, body…
- Trial name
- SPPP (NCT00724217)
- Testing
- Standard Process 21 Day Purification Program (SPPP)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Logan College of Chiropractic
Cardiovascular Diseases, Coronary Disease
Genetic Epidemiology of Hypertriglyceridemia
To determine prospectively the role of elevated plasma triglyceride (TG) as a risk factor for 20-year coronary heart disease (CHD) mortality in familial combined hyperlipidemia (FCHL) and familial hypertriglyceridemia (FHTG), the…
- Conditions
- Cardiovascular Diseases, Coronary Disease, Hyperlipidemia, Familial Combined, Hyperlipoproteinemia Type iv
- Trial name
- NCT00005368
- Sponsor
- University of Washington
Primary Hyperlipidemia
Zhibitai Capsules for the Treatment of Primary Hyperlipidemia
Exploring the benefit risk ratio of increase in dosage of Zhibitai capsules (2 capsules at a time, 2 times a day) compared to the original dosage (1 capsule at a time, 1 day)
- Trial name
- NCT06822946
- Testing
- zhibitai capsule
- Where
- 12 sites in China
- Volunteers
- 201 people
- Sponsor
- Chengdu Diao Jiuhong Pharmaceutical Factory
Dyslipidemia
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD0780 in Healthy Subjects
This study will assess the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of AZD0780 following single and multiple dose administration to healthy subjects with or without elevated Low-Density…
- Trial name
- NCT05384262
- Testing
- AZD0780, Rosuvastatin
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Sleep Apnea, Hypertension
Tri Staple Technology Stapler Used in Gastric Bypass
The objectives of this clinical trial are to assess in a pilot setting the overall performance and safety of the Endo GIA™ Stapler with Endo GIA™ SULU with Tri-Staple™ Technology when used in a gastric bypass procedure.
- Conditions
- Sleep Apnea, Hypertension, Hyperlipidemia, Coronary Artery Disease
- Trial name
- NCT01026103
- Testing
- Tri Staple Technology stapler
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Hypertriglyceridemia
Efficacy of Ethyl Icosapentate in Patients With Severe Hypertriglyceridemia
The purpose of this study is to evaluate the efficacy and safety of ethyl icosapentate in Chinese patients with severe hypertriglyceridemia.
- Trial name
- NCT04239950
- Testing
- Ethyl Icosapentate
- Where
- China
- Volunteers
- 316 people
- Sponsor
- Mochida Pharmaceutical Company, Ltd.
Hypercholesterolemia
Vytorin (10/20 Or 10/40) Compared to Atorvastatin (10 mg or 20 mg) in Patients With Coronary Artery Disease (0653A-126)(COMPLETED)
Evaluate the proportion of hyperlipaemic persons with known coronary heart disease achieving ldl-c goal as defined by the national cholesterol education program (NCEP) adult treatment panel (ATP) III guidelines
- Trial name
- NCT00442897
- Testing
- simvastatin (+) ezetimibe, Comparator: atorvastatin
- Volunteers
- 229 people
- Sponsor
- Organon and Co
Hypercholesterolemia, Coronary Heart Disease
Evaluation of the Efficacy of Rosuvastatin in Daily Practice in Untreated High Risk Patients (CHALLENGE)
In an observational multi-centre study (CHALLENGE), the effects were assessed of starting treatment with low doses of rosuvastatin in statin naive patients with a history of coronary heart disease (CHD), peripheral vascular…
- Conditions
- Hypercholesterolemia, Coronary Heart Disease, Peripheral Vascular Disease, CVA
- Trial name
- CHALLENGE (NCT00574782)
- Volunteers
- 2,660 people
- Sponsor
- AstraZeneca
Hypercholesterolemia
Centralized Pan-Middle East Survey on the Undertreatment of Hypercholesterolemia
The purpose of the study is to establish the proportion of patients on lipid-lowering pharmacological treatment reaching the LDL-C goals according to the NCEP ATP III/updated 2004 NCEP ATP III guidelines, overall and by country…
- Trial name
- CEPHEUS (NCT01025388)
- Where
- 5 sites in Saudi Arabia
- Volunteers
- 4,053 people
- Sponsor
- AstraZeneca
Obesity, Overweight
Pediatric Preventative Health Screenings - Obesity and Family-Centered Outcomes
In 2012, an Expert Panel of the National Heart Lung and Blood Institute published guidelines on cardiovascular health and risk reduction in children; among these guidelines were screening recommendations for obesity and…
- Conditions
- Obesity, Overweight, Blood Pressure, Hypercholesteremia
- Trial name
- NCT02850224
- Testing
- Motivational interviewing to elicit PCO in pediatrics
- Where
- United States
- Volunteers
- 703 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Familial Chylomicronemia, High Risk Severe Hypertriglyceridemia (SHTG)
Treatment Protocol of Plozasiran in Adults With High-Risk Severe Hypertriglyceridemia (SHTG) and in Adults and Adolescents With FCS
This is a treatment program for the use of plozasiran in adults (AROAPOC3-EAP-002) and adolescents (AROAPOC3-EAP-003) with familial chylomicronemia syndrome (FCS) as well as in adults (AROAPOC3-EAP-004) with high risk severe…
- Trial name
- NCT06796426
- Testing
- Plozasiran
- Where
- United States
- Sponsor
- Arrowhead Pharmaceuticals
Insulin Resistance, Hypertriglyceridemia
Metabolic Heterogeneity Underlying Hypertriglyceridemia: Hepatic Triglyceride Biosynthesis in Humans With Different Insulin Resistance Phenotypes
The focus of this cross-sectional study is to determine the effects of tissue-specific (adipose tissue or muscle) vs global (combined) insulin resistance (IR) on hepatic triglyceride biosynthesis in humans, and to determine…
- Trial name
- NCT05743868
- Testing
- Standardized Dinner, Premeal exercise
- Where
- Netherlands
- Volunteers
- 8 people
- Sponsor
- Yale University
Hyperlipidemia; Mixed
Investigate the Effect of Ezetimibe, Simvastatin, and Omega 3- Fatty Acids on Dyslipidemia Patients: a Pharmacokinetics Based Study
This randomized controlled pharmacokinetic based study will be carried out on patients with both sexes and various ages, plasma triglycerides levels, clinical health disorders and using different agents for treatment of their…
- Trial name
- NCT05080140
- Testing
- Ezetimibe 10mg
- Where
- Egypt
- Volunteers
- 3 people
- Sponsor
- Misr University for Science and Technology
Symptomatic Carotid Stenosis, Hypercholesterolemia
The Multicenter Atorvastatin Plaque Stabilization (MAPS) Study
The impact on cardiovascular events achieved by statin therapy seems to be mostly attributable to the cholesterol-lowering effect with a highly debated contribution of the lipid-independent pleiotropic effects.
- Conditions
- Symptomatic Carotid Stenosis, Hypercholesterolemia, Indication for Carotid Endarterectomy
- Trial name
- MAPS (NCT01053065)
- Testing
- Atorvastatin - Cholestyramine - Sitosterol
- Where
- 3 sites in Italy
- Volunteers
- 60 people
- Sponsor
- University of Padova
Hyperlipidemia
Effect of Nigella Sativa in Atorvastatin Treated Hyperlipidaemia
This study will be 8 weeks randomized, double-blind, placebo-controlled trail to assess the effect of Nigella Sativa in 84 Hyperlipidaemic patients. Participants will be assessed at baseline and after 8 weeks of intervention.
- Trial name
- NCT06422650
- Testing
- Nigella Sativa capsule 500mg
- Where
- Bangladesh
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Hypercholesterolemia, Postmenopause
Vascular and Metabolic Effects of Hormone Therapy Combined With L-Arginine in Postmenopausal Women
Estrogen therapy has been associated with reduced risk of coronary heart disease events in observational studies of postmenopausal women.
- Trial name
- NCT00001752
- Testing
- L-arginine, Estrogen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Hyperlipidemia
Efficacy and Safety of Morning Versus Evening Intake of Simvast Controlled Release (CR) Tablet in Patients With Hyperlipidemia
The purpose of this study is to evaluate the efficacy and safety of morning versus evening intake of Simvastatin Controlled Release tablet 20mg for 8 weeks in patients with hyperlipidemia.
- Trial name
- NCT00973115
- Testing
- Simvastatin CR
- Where
- South Korea
- Volunteers
- 132 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Primary Prevention
ProSALUTE: Community Program for Cardiovascular Health
The purpose of this study is to determine the efficacy and cost/effectiveness (change in CV risk factors and lifestyle vs costs) of ProSALUTE as a new organizational model of primary CV prevention.
- Trial name
- ProSALUTE (NCT03129165)
- Testing
- Screening and prevention of CVD
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Centro Cardiologico Monzino
Coronary Artery Disease, Hypertension
Acute Probiotic Supplementation and Endothelial Function
One in every two deaths in the United States is caused by cardiovascular disease. Despite strong mechanistic links established between a diet rich in lipids and the pathogenesis of cardiovascular disease, therapeutic advances…
- Conditions
- Coronary Artery Disease, Hypertension, Hyperlipidemias, Peripheral Vascular Diseases
- Trial name
- NCT04364074
- Testing
- Goodbelly
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Medical College of Wisconsin
Hyperlipoproteinemia
Safety, Tolerability,Pharmacokinetics(PK)and Pharmacodynamics(PD)Assessment of LCQ908 in Patients With Severe Hypertriglyceridemia
This study will assess safety, tolerability, and effect of LCQ908 on blood lipids in patients with severe hypertriglyceridemia.
- Trial name
- NCT01146522
- Testing
- LCQ908
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Novartis Pharmaceuticals
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