Clinical trials: Lipemia
Type 2 Diabetes
Efficacy of Lapaquistat Acetate in Subjects Currently Treated With Lipid-Lowering Therapy.
The purpose of the study is to determine the efficacy of lapaquistat acetate, once daily (QD), taken with established lipid-lowering therapy in subjects with type 2 diabetes mellitus.
- Trial name
- NCT00251680
- Testing
- Lapaquistat acetate and lipid-lowering therapy, Lipid-lowering therapy
- Where
- 77 sites in United States, Czechia and 7 more
- Volunteers
- 400 people
- Sponsor
- Takeda
Hyperlipidemias
Acupuncture and Moxibustion for Hyperlipemia
The purpose of this study is to evaluate the effect of 12 weeks of acupuncture and moxibustion compared with active control, on absolute and percent change from baseline in low-density lipoprotein cholesterol (LDL-C) among those…
- Trial name
- AMH-RCT (NCT02269046)
- Testing
- acupuncture and moxibustion, Simvastatin, Therapeutic Lifestyle Change
- Where
- 3 sites in China
- Volunteers
- 210 people
- Sponsor
- The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
Hypercholesterolemia, Heterozygous Familial Hypercholesterolemia
A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653C in Japanese Participants With Hypercholesterolemia (MK-0653C-384)
This study will assess the safety and tolerability of Ezetimibe (EZ) 10 mg/Atorvastatin (Atora) 10 mg and EZ 10mg/Atora 20 mg fixed-dose combination (FDC) in Japanese participants with hypercholesterolemia uncontrolled with…
- Trial name
- NCT02460159
- Testing
- EZ 10 mg/Atorva 20 mg FDC, EZ 10 mg/Atorva 10 mg FDC
- Volunteers
- 135 people
- Sponsor
- Organon and Co
Homozygous Familial Hypercholesterolemia
Trial Evaluating PCSK9 Antibody in Subjects With LDL Receptor Abnormalities
A study to determine the safety, tolerability, and efficacy of evolocumab (AMG 145) in patients with homozygous familial hypercholesterolemia (HoFH).
- Trial name
- TESLA (NCT01588496)
- Testing
- Evolocumab
- Where
- 21 sites in United States, Belgium and 10 more
- Volunteers
- 58 people
- Sponsor
- Amgen
Primary Hypercholesterolemia, Mixed Dyslipidemia
Study to Assess In-home Use of Evolocumab (AMG 145) Using a Prefilled Syringe or a Prefilled Autoinjector/Pen
The primary objective of this study was to assess users' ability to administer a full dose of evolocumab in home-use using either a pre-filled syringe or autoinjector/pen.
- Trial name
- NCT01849497
- Testing
- Evolocumab Pre-filled Syringe, Evolocumab AI/pen
- Where
- 26 sites in United States, Canada
- Volunteers
- 149 people
- Sponsor
- Amgen
Hyperlipidemia, Diet Therapy
Almond Dose Response Study.
To assess the effects of almonds on coronary heart disease (CHD) risk factors (serum lipids, measurements of oxidative stress and nitric oxide production) when added to the diets of subjects with high cholesterol.
- Conditions
- Hyperlipidemia, Diet Therapy, Cardiovascular Disease
- Trial name
- NCT00507520
- Testing
- Full dose almonds, Half dose almonds+half dose muffin, Full dose whole wheat muffin
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- University of Toronto
Lipid Disorders
Lipoprotein Interactions and Platelet Function in Healthy Individuals and Those With Lipid Disorders
This study looks at how lipoproteins, which are particles in the blood that transport cholesterol, influence heart and blood vessel health.
- Trial name
- NCT06747000
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Severe Hypertriglyceridemia
Study to Evaluate ARO-APOC3 in Adults With Severe Hypertriglyceridemia
The purpose of AROAPOC3-2001 is to evaluate the efficacy and safety of ARO-APOC3 in participants with severe hypertriglyceridemia. Participants will receive 2 subcutaneous injections of ARO-APOC3.
- Trial name
- SHASTA-2 (NCT04720534)
- Testing
- ARO-APOC3
- Where
- 74 sites in United States, Australia and 6 more
- Volunteers
- 229 people
- Sponsor
- Arrowhead Pharmaceuticals
High Cholesterol
Effect of Policosanol as Monotherapy and Adjunctive to Statin Therapy
To determine the effects of policosanol on the cholesterol profile.
- Trial name
- NCT00510809
- Testing
- Policosanol, Policosanol Plus Already In Use Statin Therapy
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- James Backes, PharmD
Hypercholesterolemia
Artichoke and Bergamot Phytosome
According to WHO data, about 50% of deaths each year are caused by cardiovascular disease. One of the strategies for prevention of cardiovascular diseases, in addition to a correct lifestyle, is to implement therapies that reduce…
- Trial name
- NCT04697121
- Testing
- Combined Bergamot phytosome and Artichoke leaf dry extract
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Hypercholesterolemia; ASCVD; Pregnancy
Evolocumab Pregnancy Exposure Registry
This is a prospective observational registry study to evaluate fetal, infant and childhood outcomes in women exposed to evolocumab during pregnancy
- Trial name
- NCT02957604
- Testing
- evolocumab
- Volunteers
- 140 people
- Sponsor
- Amgen
Elevated Cholesterol
Impact of Alpine Dairy Products on Blood Lipid Levels
Elevated blood lipid levels are one of the main risk factors for cardiovascular disease. To manage elevated blood lipid levels in otherwise healthy people at low risk of cardiovascular disease, lifestyle changes are recommended…
- Trial name
- NCT06693947
- Testing
- Alpine dairy products
- Where
- Switzerland
- Volunteers
- 29 people
- Sponsor
- University of Fribourg
Hyperlipidemias
Hypolipidemic Effect of Adansonia Digitata
Adansonia digitata L. (AD) also known as Baobab is a huge tree that grows in many countries in sub-Saharan Africa. Many studies talking about AD biological activity including hypolipidemic, antioxidant and antimicrobials in…
- Trial name
- AD (NCT04564352)
- Testing
- Adansonia digitata
- Where
- Saudi Arabia
- Volunteers
- 70 people
- Sponsor
- Taibah University
Chronic Kidney Disease, High Cholesterol
The Effect of Atorvastatin on Endothelial Cell Dysfunction in Chronic Kidney Disease
The purpose of this study is to see if patients with chronic kidney disease have endothelial cells that don't function properly, which is thought to be a marker for cardiovascular risk.
- Trial name
- NCT02133534
- Testing
- Atorvastatin
- Volunteers
- 1 people
- Sponsor
- Duke University
Hypercholesterolemia, Atherosclerosis
Ezetimibe Plus Simvastatin Versus Simvastatin in Patients With Hypercholesterolemia and Coronary Risk Factors (P03405)
The study was designed to assess whether 6 weeks of co-administration of ezetimibe and simvastatin is more effective than simvastatin monotherapy in allowing patients in the CHD risk strata of the NCEP III guidelines to achieve…
- Trial name
- NCT00651014
- Testing
- Ezetimibe
- Volunteers
- 82 people
- Sponsor
- Organon and Co
Hypertension, Hypercholesterolemia
Effects of Atorvastatin on Blood Pressure and Urinary Albumin Excretion
To evaluate the possible effects of atorvastatin on ambulatory blood pressure, urinary albumin excretion, insulin resistance and arterial stiffness in hypertensive patients, beyond those on lipid profile.
- Trial name
- NCT01126684
- Testing
- Atorvastatin
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Aristotle University Of Thessaloniki
Hyperlipidemia
Effect of InnoSlim® on Blood Sugar and Blood Lipids Regulation in Humans
InnoSlim® has been studied for enhancing metabolic functions whereas many lab studies have demonstrated the potential efficacy of InnoSlim® for the blood sugar and blood lipids regulation.
- Trial name
- NCT04201314
- Testing
- InnoSlim®
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Mixed Dyslipidemia, Hypercholesterolemia
Efficacy and Safety of Fluvastatin in Different Doses in Adults With Mixed Dyslipidemia or Primary Hypercholesterolemia
The purpose of the study is to evaluate the safety and tolerability of fluvastatin 80 mg in a Chinese population. This study is not recruiting patients in the US.
- Trial name
- NCT00136799
- Testing
- Fluvastatin
- Where
- China
- Volunteers
- 325 people
- Sponsor
- Novartis
Insulin Resistance, Obesity
Pilot Study of GLY-LOW Supplementation in Postmenopausal Women With Obesity
A combination of generally regarded as safe (GRAS) compounds named GLY-LOW, which included: alpha lipoic acid, pyridoxamine, nicotinamide, piperine and thiamine, were examined in pre-clinical experiments.
- Conditions
- Insulin Resistance, Obesity, Cardiovascular Diseases, Cognitive Impairment
- Trial name
- NCT06242535
- Testing
- GLY-LOW
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Hoskinson Health and Wellness Clinic
Familial Hypercholesterolemia
Coronary and Heart Effects of Early Treatment in Familial Hypercholesterolemia
This study evaluates plaque burden and characteristics in early-treated FH patients compared to late-treated FH patients and healthy individuals.
- Trial name
- CHEETAH (NCT05352386)
- Testing
- Coronary computed tomography angiography (CCTA)
- Where
- Netherlands
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
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