Clinical trials: Lipemia
Cardiovascular Risk Factor
Virtual Lifestyle Intervention for Weight Management and Cardiovascular Heal
This is a 90-day, single-arm, open-label, fully virtual community lifestyle intervention study evaluating the effects of a multicomponent lifestyle intervention on weight management and cardiovascular health.
- Trial name
- NCT07572721
- Testing
- Multicomponent Virtual Lifestyle Intervention
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Truemedicine Inc
Hypercholesterolemia
A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia
This study is researching an experimental drug called alirocumab, referred to as "study drug". In the United States, alirocumab is approved for the treatment of hypercholesterolemia (high blood cholesterol levels).
- Trial name
- ASCEND-QW (NCT07477704)
- Testing
- Alirocumab
- Where
- 34 sites in United States
- Volunteers
- 438 people
- Sponsor
- Regeneron Pharmaceuticals
Cardiovascular Diseases, Circadian Rhythm Sleep Disorder, Shift Work Type
Effect of a Grape Seed Proanthocyanidin Extract (GSPE) on LDL Cholesterol Levels in Rotating Night Shift Workers
The physiological processes of the body present daily oscillations called circadian rhythm. The circadian rhythm is essential for maintaining the vital functions of organisms, intervening directly and indirectly in a multitude of…
- Conditions
- Cardiovascular Diseases, Circadian Rhythm Sleep Disorder, Shift Work Type, Cholesterol Level, High
- Trial name
- CIRCAFENOL (NCT06422741)
- Testing
- grape seed proanthocyanidin extract
- Where
- 2 sites in Spain
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Fundació Eurecat
Hypertriglyceridemia
Evaluation of Safety and Effects of SLx-4090 After Dosing for 14 Days in Subjects With High Triglycerides
The purpose is to investigate the effect of oral doses of SLx-4090 over 14 days on subjects with high triglycerides.
- Trial name
- NCT00562575
- Testing
- SLx-4090
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Response Pharmaceuticals
Hyperlipidemia
Single Radiolabeled Dose Study to Investigate the Absorption, Metabolism and Excretion of [14C]-ETC-1002
This Phase 1 study will assess the mass balance recover of carbon-14 (14C) labelled ETC-1002 and the routes and rates of excretion of [14C]-ETC-1002
- Trial name
- NCT02044627
- Testing
- [14C-ETC-1002]
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Esperion Therapeutics, Inc.
Familial Hypercholesterolemia
Developing and Implementing Familial Hypercholesterolemia Registry
Familial hypercholesterolemia (FH) is a most prevalent genetic disorder define as high cholesterol level and premature death. The prevalence of FH reported in few countries however unknown in Iran.
- Trial name
- NCT02865694
- Testing
- Cascade
- Where
- Iran
- Volunteers
- 500 people
- Sponsor
- Isfahan University of Medical Sciences
Diabetes Mellitus, Type 2, Obesity
Culturally-Adapted Diet for Puerto Rican Adults
This pilot project will determine whether a diet culturally-adapted to Puerto Ricans can effectively decrease cardiometabolic risk for diabetes.
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Hypertension, Dyslipidemias
- Trial name
- NCT03975556
- Testing
- Culturally tailored food and diet advice, Standard healthy eating advice
- Where
- Puerto Rico
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Hypercholesterolemia
Intervention With Lupin Kernel Fibre in Hypercholesterolemic Subjects
The objective of the conducted study was to determine the efficacy of lupin kernel fibre-enriched food (Lupinus angustifolius Boregine) on prevention of risk factors for gastrointestinal or cardiovascular diseases.
- Trial name
- NCT01035086
- Testing
- fabricated food
- Where
- Germany
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Jena
High Cholesterol, Cardiovascular Disease
The RISAP-study: a Complex Intervention in Risk Communication and Shared Decision-making in General Practice
General practitioners (GPs) and patients find it difficult to talk about risk of future disease, especially when patients have asymptomatic conditions, and treatment options are unlikely to cause immediate perceptible…
- Trial name
- RISAP (NCT01187056)
- Testing
- Training programme
- Volunteers
- 179 people
- Sponsor
- University of Aarhus
Lipid Metabolism Disorders, Sterols
Effect of Different Fat Enriched Meats on the Hepatic Cholesterol Synthesis
The objective of the study is to assess the effect of two diets with different fat composition on cholesterol metabolism. The study was a randomized cross-over trial where volunteers follow two study periods with different types…
- Conditions
- Lipid Metabolism Disorders, Sterols, Diet, High-Fat, Cholesterol
- Trial name
- NCT02259153
- Testing
- Changes in cholesterol metabolism, Lean red meat diet, Fat red meat diet
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Instituto Aragones de Ciencias de la Salud
Hypertriglyceridemia
A Phase 3 STudy of CaPRe In LOwering Very hiGh TriglYcerides (TRILOGY 1)
The primary objective of this study is to determine the efficacy of CaPre 4 g daily, compared to placebo, in lowering fasting triglyceride (TG) levels in patients with fasting TG levels ≥500 mg/dL and ≤1500 mg/dL (≥5.7 mmol/L and…
- Trial name
- TRILOGY 1 (NCT03398005)
- Testing
- CaPre
- Where
- 69 sites in United States
- Volunteers
- 256 people
- Sponsor
- Grace Therapeutics Inc.
Hypercholesterolemia, Hyperlipidemias
Lipid-lowering Effect of a Plant Stanol Ester Supplement Product
Purpose of the study is to determine the effect of the investigational products as consumed with a meal on serum lipids, primarily on LDL cholesterol.
- Conditions
- Hypercholesterolemia, Hyperlipidemias, Dyslipidemias
- Trial name
- NCT02221297
- Testing
- Supplement product with plant stanol ester
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Raisio Group
Familial Hypercholesterolemia, Cardiac Event
Familial Hypercholesterolemia Amongst Patients With Acute Coronary Syndrome
Familial hypercholesterolemia (FH) is a most prevalent genetic disorder, defines as high cholesterol level and premature death. The prevalence of FH has been reported in few countries however unknown in Iran.
- Conditions
- Familial Hypercholesterolemia, Cardiac Event, Acute Coronary Syndrome
- Trial name
- NCT02870660
- Testing
- Registry
- Where
- Iran
- Volunteers
- 500 people
- Sponsor
- Isfahan University of Medical Sciences
Hypercholesterolemia, Familial
Carotid IMT (Intima Media Thickening) Study (0524A-041)(TERMINATED)
This is a 105-week clinical study in patients with heterozygous familial hypercholesterolemia on intensive Low Density Lipoprotein-cholesterol (LDL-C) lowering therapy intended to assess the affects of MK0524A on carotid intima…
- Trial name
- ACHIEVE (NCT00384293)
- Testing
- Comparator: niacin (+) laropiprant (MK0524A)
- Volunteers
- 937 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Healthy, Hypercholesterolemia
Health Effects of Consuming Olive Pomace Oil
Healthy and at risk (hypercholesterolemic) subjects consumed during 4 weeks 45 g/d of either olive pomace oil (OPO) or sunflower oil (SO) as the only dietary fat in a randomized, crossover trial.
- Trial name
- ORUJOSALUD-2 (NCT04998695)
- Testing
- Olive pomace oil, Sunflower oil
- Where
- Spain
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Instituto de Ciencia y Tecnología de Alimentos y Nutrición
Severe Hypertriglyceridemia
Safety and Efficacy of MAT9001(Omega-3-pentaenoic Acid) in Subjects With Triglycerides ≥500 mg/dL and <2000 mg/dL
To determine the efficacy of MAT9001 compared to placebo in lowering fasting triglyceride levels in subjects with very high fasting triglyceride levels ≥ 500 and < 2000 mg/dL.
- Trial name
- AMPLIFY (NCT04662528)
- Testing
- MAT9001 (omega-3 pentaenoic acid)
- Sponsor
- Matinas Biopharma, Inc
Hypercholesterolemia
A Multicenter, Randomized, Open Label Study to Evaluate the Lipid Lowering Efficacy and Safety of Vytorin® 10/20 vs. Atorvastatin 10mg in Hypercholesterolemia Patients With Metabolic Syndrome in Korea (0653A-129)(COMPLETED)
Prevalence of metabolic syndrome in korea is increasing. There is no clinical trial targeting on such increasing populations like metabolic syndrome patients with Vytorin® in korea.
- Trial name
- NCT00496730
- Testing
- simvastatin (+) ezetimibe, Comparator: atorvastatin
- Volunteers
- 256 people
- Sponsor
- Organon and Co
Hypercholesterolemia, Mixed Dyslipidemia
Niacin (+) Laropiprant (TREDAPTIVE) Re-examination Study (MK-0524A-119)
This survey is being conducted to assess the safety and efficacy of niacin (+) laropiprant (TREDAPTIVE) in usual practice in Korea according to the new product re-examination regulations of the Korean Food and Drug Administration.
- Trial name
- NCT01228019
- Testing
- Niacin (+) laropiprant
- Volunteers
- 1,166 people
- Sponsor
- Merck Sharp & Dohme LLC
Hypercholesteremia
Pattern of Statins Use in Catalonia
To describe the new statins prescription pattern in Catalonia (getting their first prescription for any statin, or receiving a change in their statin treatment including switching, changing in doses or adding ezetimibe/fibrates)…
- Trial name
- NCT01477944
- Volunteers
- 180,723 people
- Sponsor
- AstraZeneca
Spinal Cord Injuries
Energetic Response to Feeding and Exercise in SCI
This study investigates the effect of various forms of upper extremity exercise on postprandial glycemia and lipemia in persons with spinal cord injury (SCI).
- Trial name
- CRIT (NCT03545867)
- Testing
- Seated control (CON), Moderate intensity continuous (MICT), High intensity interval training (HIIT)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Miami
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