Clinical trials: Lipemia
Hypercholesterolemia, Hypertension
Evaluating "Health at Every Size"(HAES) as an Alternative Obesity Treatment Model
Increasingly more individuals are trying to lose weight. Indeed, many women, regardless of their size, experience a life-long battle and preoccupation with their weight.
- Conditions
- Hypercholesterolemia, Hypertension, Depression, Diabetes Mellitus, Type 2
- Trial name
- NCT00074633
- Testing
- Health at Every Size (HAES), Diet (Traditional, moderate energy restriction)
- Where
- 2 sites in United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Hyperlipidemia
The Safety, Tolerability and Efficacy of Multiple Subcutaneous Injections of SHR-1209 in Subjects With Hyperlipidemia
This is a randomized, double-blind, placebo- controlled phaseⅠb/Ⅱclinical study. Totally 108 subjects are planned to enrolled with 36 subjects in three low-dose groups (group 1, group 2 and group 3) and 72 subjects in three…
- Trial name
- NCT03944109
- Testing
- SHR-1209
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Lysosomal Acid Lipase Deficiency
A Study to Identify and Characterize LAL-D Patients in High-risk Populations
The objective of this study is to determine the frequency of Lysosomal Acid Lipase Deficiency (LAL D) by lysosomal acid lipase (LAL) enzyme activity assay in patients who are considered to be at risk.
- Trial name
- NCT02345421
- Where
- 15 sites in United States
- Volunteers
- 640 people
- Sponsor
- Alexion Pharmaceuticals, Inc.
Hypertriglyceridemia
A Study to Evaluate the Lipid Regulating Effects of 1-Methylnicotinamide (1-MNA)
A randomized, double-blind, placebo-controlled, dose-ranging, multi-center study. Following a 6-8 week placebo and dietary-controlled baseline period, approximately 195 men and women with either hypertriglyceridemia or mixed…
- Trial name
- NCT00519714
- Testing
- 1-Methylnicotinamide (1-MNA)
- Where
- Canada
- Volunteers
- 195 people
- Sponsor
- Montreal Heart Institute
Hypercholesterolemia
Korean Rosuvastatin Effectiveness Study in Nondiabetic Metabolic Syndrome
The primary objective of this study is to compare the effect of rosuvastatin 10mg with atorvastatin 10mg in the percentage reduction of LDL-C in Subjects with metabolic syndrome after 6 weeks of treatment.
- Trial name
- NCT00335699
- Testing
- Rosuvastatin
- Where
- 7 sites in South Korea
- Volunteers
- 370 people
- Sponsor
- AstraZeneca
Hypercholesterolemia
Study of 3,5-Diiodothyropropionic Acid (DITPA) in Hypercholesterolemic Patients
The natural thyroid hormones, thyroxine (T4) and triiodothyronine (T3), are known to have a cholesterol-lowering effect. Their pharmacologic use for this purpose is limited, however, by their actions on other organs, including…
- Trial name
- NCT00311987
- Testing
- 3,5-Diiodothyropropionic acid (DITPA) therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins University
Diabetes, Hypercholesterolaemia
The Effect of Providing Genetic Risk Information on Lifestyle Behaviors in African Americans
Cardiovascular disease (CVD) is a major and persistent health disparity for African Americans. Linking GAINS is a randomized pilot and feasibility study designed to evaluate whether receiving genetic risk information early in a…
- Conditions
- Diabetes, Hypercholesterolaemia, Hypertension, Obesity Type 2 Diabetes Mellitus
- Trial name
- LINKING GAINS (NCT07833384)
- Testing
- Color Genomics Genetic Testing Panels
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Atherosclerosis, LDL-hypercholesterolemia
Effect of Mipomersen on LDL-Cholesterol Levels in Patients Treated by Regular Apheresis
Elevated LDL-cholesterol is a major risk factor for heart disease. In patients with heart disease LDL-cholesterol should be lowered to levels below 70 mg/dl to prevent progression of disease.
- Trial name
- MICA (NCT01598948)
- Testing
- mipomersen
- Where
- Germany
- Volunteers
- 17 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Patients With Metabolic Syndrome
A Randomized, Double-Blind Trial Comparing the Efficacy and Safety of Fenofibrate, Metformin, Their Combination and Placebo in Patients With Metabolic Syndrome.
The purpose of this study was to study the effect of different combinations of fenofibrate and metformin on the cluster of metabolic syndrome (MetS) biochemical abnormalities, and to determine the dose combination allowing…
- Trial name
- NCT00703755
- Testing
- Fenofibrate /Metformin
- Where
- 101 sites in Canada, Finland and 7 more
- Volunteers
- 2,288 people
- Sponsor
- Solvay Pharmaceuticals
Type 2 Diabetes Mellitus, Hypertriglyceridemia
The Effect of Omega-3 FA on Hypertriglyceridemia in Patients With T2DM(OCEAN)
The purpose of this study is to conduct a multicenter randomized, double-blind, placebo-controlled clinical trial, evaluating the effects and change of lipid metabolism, especially of triglyceride after omega-3 administration in…
- Trial name
- NCT03120299
- Testing
- Omega-3 fatty acid
- Where
- China
- Volunteers
- 309 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Hypertriglyceridemia
Trial of Lovaza in Adolescents With Mild to Moderately Elevated Triglycerides
The investigators will conduct a randomized clinical trial to evaluate the efficacy of Lovaza (formerly known as Omacor) in reducing triglyceride levels in youth ages 10-19 years old whose baseline triglycerides range from 150…
- Trial name
- NCT00672633
- Testing
- Lovaza
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Boston Children's Hospital
Coronary Artery Disease, Atherosclerosis
The CHORAL Flow Study
CHORAL Flow is a randomised, double blinded, placebo-controlled trial of the effects of evolocumab on coronary flow at 12 weeks.
- Conditions
- Coronary Artery Disease, Atherosclerosis, Hyperlipidemias
- Trial name
- CHORAL (NCT04073134)
- Testing
- Evolocumab
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Imperial College London
Hyperlipidemias
A Study to Evaluate SGB-3403 in Healthy Volunteers and Subjects With Elevated Low-Density Lipoprotein Cholesterol (LDL-C)
This study is a randomized, double-blind, placebo-controlled, single ascending dose (SAD) and multiple ascending doses (MAD) of SGB-3403 when single administered subcutaneously to healthy volunteers and multiple administered…
- Trial name
- NCT06239714
- Testing
- SGB-3403, Atorvastatin
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Suzhou Sanegene Bio Inc.
Hyperlipidemias, Metabolic Syndrome X
Effect of Dietary Amino Acid Profile on Lipoprotein Metabolism, Vascular Reactivity and Inflammatory Markers
The aim of this study is to explore the significance of the Lys:Arg ratio on responses of lipids and lipoprotein concentrations to dietary proteins and to evaluate the effects of dietary Lys:Arg on cardiovascular disease risk…
- Conditions
- Hyperlipidemias, Metabolic Syndrome X, Cardiovascular Diseases
- Trial name
- NCT00175084
- Testing
- Comparison of dietary protein amino acid profile
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tufts University
Drug Induced Hyperglycemia, Secondary Hyperlipidemia
Long Term Antihypertensive Exposure and Adverse Metabolic Effects: PEAR Follow-Up Study
This is a research study of the long term effects on blood sugar and cholesterol of blood pressure lowering medications. People are invited to participate in this research study if they participated in the Pharmacogenomic…
- Trial name
- NCT01409434
- Testing
- Oral Glucose Tolerance Test
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Florida
Hypercholesterolemia
Effect of the Consumption of a Fermented Milk Enriched With Plant Sterols
The purpose of this study is to investigate the cholesterol lowering effect of a drinkable low fat fermented milk enriched with plant sterol after 3 and 6 weeks of daily consumption in midly hypercholesterolemic people not…
- Trial name
- NCT01340287
- Testing
- 1- plain low-fat dairy fermented product (drinkable) enriched with plant sterols-esters (1,6g /day equivalent as free sterols)., 2- plain low-fat dairy fermented product (drinkable) without plant sterols-esters
- Where
- United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Hyperlipidemia, Pregnancy
Lipid Profile as Predictor of Adverse Maternal and Neonatal Outcomes: A Pilot Study
The purpose of this study is to ascertain lipid profiles during pregnancy, specifically during the 24-28 week gestation and again near term at 36 weeks gestation.
- Trial name
- NCT05535660
- Testing
- Lipid panel
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Familial Hypercholesterolaemia, Hypercholesterolaemia
Specified Drug-use Survey of Leqvio for s.c. Injection.
The objective of this study is to evaluate the long-term safety of Leqvio in patients with familial hypercholesterolaemia or hypercholesterolaemia in post-marketing clinical practice
- Trial name
- NCT06275724
- Testing
- inclisiran
- Where
- 107 sites in Japan
- Volunteers
- 585 people
- Sponsor
- Novartis Pharmaceuticals
Hyperlipidemias
To Explore the Treatment Effect of Various Commercially Available Statins on Patients With Hyperlipidemia
The primary objective is to survey the efficacy of various commercially available statins (a class of lipid-lowering agents, for example, rosuvastatin, atorvastatin, simvastatin, lovastatin, pravastatin and fluvastatin) under…
- Trial name
- NCT00726362
- Where
- 8 sites in Taiwan
- Volunteers
- 3,270 people
- Sponsor
- AstraZeneca
Cholesterol Level, High
Effects of a Single Dose of Brazil Nuts on Blood Lipids
Several studies have shown that regular intake of nuts may improve blood lipids. However, few studies have investigated the effects on blood lipids after a single intake of nuts.
- Trial name
- NCT05537324
- Testing
- Brazil nut, Coconut
- Where
- Norway
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Skogli Health and Rehabilitation Center
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