Clinical trials: Lipemia
Hypercholesterolemia
Study Assessing Safety, Immunogenicity and LDLc -Lowering Activity of 2 PCSK9 Targeting AFFITOPE Vaccines in Healthy Subjects
Study AFF012 is a single blind, single-center, randomized, placebo-controlled, parallel group, phase I clinical trial of repeated administration by subcutaneous injection of a single dose of one of two different proprotein…
- Trial name
- AFF012 (NCT02508896)
- Testing
- AFFITOPE® AT04A+adjuvant, AFFITOPE® AT06A+adjuvant, Adjuvant without active component
- Where
- Austria
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Affiris AG
Hypertension, Diabetes
Arts & Health Education to Improve Health, Resilience, and Well-Being
This is an 8-week randomized controlled trial to help address health, resilience, and well-being. Participants are randomized into either a health education group or an arts-based health education group.
- Conditions
- Hypertension, Diabetes, Obesity, COPD
- Trial name
- NCT04154579
- Testing
- HeRe We Arts, HeRe We Ed
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Lisa Gallagher
Hypertriglyceridemia
Bioavailability of EPA and DHA From Two Dietary Supplements
The primary objective of this study is to test the effects of two different fish oil products containing DHA and EPA by comparing the omega-3 fatty acid levels in the blood.
- Trial name
- NCT01908374
- Testing
- DHA-rich fish oil versus Phospholipid-rich fish oil
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Arctic Nutrition AS
Hypercholesterolemia
Validating the "Foods for Health" Portfolio of Functional Food Products
The objective of this research project is to investigate the ability to affect cardiovascular disease (CVD) risk factors through a novel, easily implemented functional food-based approach.
- Trial name
- NCT02341924
- Testing
- Portfolio of functional foods, Control foods
- Where
- 2 sites in United States, Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Hypertriglyceridemia
Postprandial Lipid Metabolism in Patients With Hypertriglyceridemia and Normo-lipidemic Controls: Medium Chain Fatty Acids (MCT) in Comparison to Long-chain, Saturated Fatty Acids (SFA) and Mono-unsaturated Fatty Acids (MUFA)
Postprandial lipid metabolism will be evaluated in patients with hypertriglyceridemia and normo-lipidemic controls; different fats will be used (saturated fatty acids, mon-unsaturated fatty acids and medium chain fatty acids) for…
- Trial name
- NCT03846908
- Testing
- MCT, SFA, MUFA
- Where
- Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Hyperlipidemia in Children
Virtual Reality Intervention in Children With Hyperlipidemia
Children with hyperlipidemia have elevated blood lipid levels, which increase the risk of developing cardiovascular diseases later in life.
- Trial name
- NCT07344389
- Testing
- Virtual Reality Training, Conventional Physiotherapy
- Volunteers
- 32 people
- Sponsor
- Hacettepe University
Hypercholesterolemia, Hypertension
Evaluating the Efficacy and Safety of Co-administrated Rosuvastatin/Ezetimibe and Telmisartan/Amlodipine
The purpose of this study is to evaluate the efficacy and safety of co-administrated Rosuvastatin/Ezetimibe and Telmisartan/Amlodipine in patients with primary hypercholesterolemia and essential hypertension.
- Trial name
- NCT04158076
- Testing
- Ezetimibe/Rosuvastatin, Telmisartan, Telmisartan/Amlodipine 80 Mg-5 Mg ORAL TABLET
- Where
- South Korea
- Volunteers
- 131 people
- Sponsor
- Addpharma Inc.
Mixed Hyperlipidemia
Comparison of the Efficacy and Safety of AtorVastatin mOnotherapy vs. Combination Atorvastatin/Fenofibric Acid
The purpose of this study is to compare combination atorvastatin/fenofibric acid 10/135mg with atorvastatin 20mg monotherapy in the mixed hyperlipidemia who were not at lipid goals with atorvastatin 10mg monotherapy.
- Trial name
- AVOCADO (NCT01974297)
- Testing
- Atorvastatin 10mg, fenofibric acid 135mg, atorvastatin 20mg
- Where
- South Korea
- Volunteers
- 194 people
- Sponsor
- Sang Hak Lee
Hypercholesterolaemia, Atherosclerosis
Ezetimibe Plus Simvastatin Versus Simvastatin in Untreated Subjects With High Cholesterol (P03435)
This study will assess whether co-administration of ezetimibe 10 mg with simvastatin 20 mg will be more effective than treatment with simvastatin 20 mg alone in reducing LDL-C concentrations when administered for 6 weeks.
- Trial name
- NCT00653835
- Testing
- Ezetimibe + Simvastatin, Simvastatin
- Volunteers
- 153 people
- Sponsor
- Organon and Co
Coronary Artery Disease, Hypercholesterolemia
The Role of Atorvastatin on Monocyte Function in Patients With Coronary Artery Disease and Hypercholesterolemia
The aim of this study is to determine, whether an intensified atorvastatin therapy can improve monocyte function in patients with coronary artery disease and hypercholesterolemia.
- Conditions
- Coronary Artery Disease, Hypercholesterolemia, Monocyte Function
- Trial name
- NCT00329069
- Testing
- atorvastatin (drug)
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Type 2 Diabetes, Hyperlipidemias
The Medicines Advice Service Evaluation
The purpose of this study is to find out whether talking to a pharmacist on the telephone can help to support people taking medicine for a long-term condition.
- Trial name
- NCT01864239
- Testing
- Medicines Advice Service
- Where
- United Kingdom
- Volunteers
- 677 people
- Sponsor
- University College, London
Hypercholesterolemia
EZETROL® Re-examination Study (MK0653-175)(COMPLETED)
This survey is conducted for preparing application materials for re-examination under the Pharmaceutical Affairs Laws and its Enforcement Regulation, its aim is to reconfirm the clinical usefulness of EZETROL® through collecting…
- Trial name
- NCT01070953
- Volunteers
- 4,467 people
- Sponsor
- Organon and Co
Hyperlipidemia
Study of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Inclisiran in Chinese Participants With Elevated Serum LDL-C
Study to evaluate the pharmacokinetics and pharmacodynamics of inclisiran treatment given as single subcutaneous injection in Chinese participants with elevated low-density lipoprotein cholesterol (LDL-C) despite treatment with…
- Trial name
- ORION-14 (NCT04774003)
- Testing
- 100 mg inclisiran sodium (equivalent to 94.5 mg inclisiran), 300 mg inclisiran sodium (equivalent to 284 mg inclisiran)
- Where
- 3 sites in China
- Volunteers
- 40 people
- Sponsor
- Novartis Pharmaceuticals
Familial Hypercholesterolemia, Cardiac Event
Detection of Familial Hypercholesterolaemia in Cardiovascular Disease Registry
Familial hypercholesterolaemia (FH) is an autosomal dominant somatic mutation commonly located on the LDL-receptor, APOB, and PCKS9 gene.
- Conditions
- Familial Hypercholesterolemia, Cardiac Event, Percutaneous Coronary Intervention
- Trial name
- NCT02778646
- Volunteers
- 1,622,948 people
- Sponsor
- University College, London
Hyperlipidemias
Efficacy and Safety of Red Ginseng Concentrated Powder on Improvement of Blood Triglyceride Level
This study was conducted to investigate the effects of daily supplementation of Red Ginseng Concentrated Powder on Improvement of Blood Triglyceride Level.
- Trial name
- NCT03828188
- Testing
- Red Ginseng Concentrated Powder
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Insulin Resistance, Hypertriglyceridemia
Comparing Tricor, Avandia, or Weight Loss to Lower Cardiovascular Risk Factors in People With High Triglycerides.
Approximately 1/4 of the US population has insulin resistance and the associated risk factors such as elevated lipid levels -triglycerides (type of fat from what we eat and what the liver produces and low HDL cholesterol which is…
- Trial name
- NCT00186537
- Testing
- Rosiglitazone, Fenofibrate, Weight Loss
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Stanford University
Lp(A), Hypercholesterolemia
Argentine Registry of Lp(a)
The Argentine Registry on Lipoprotein(a) (LP(a)), orchestrated by the Argentine Group for LP(a) Study, stands as a pioneering and extensive prospective initiative.
- Conditions
- Lp(A), Hypercholesterolemia, Cardiovascular Diseases, Diabete Type 2
- Trial name
- GAELpa (NCT06297239)
- Where
- Argentina
- Volunteers
- 1,000 people
- Sponsor
- School of Medicine. National University of Cuyo
Cardiovascular Diseases, Heart Diseases
Evaluation of Childhood Blood Pressure and Lipid Screening
To help clarify the validity, reliability, and utility of blood pressure (BP) and lipid screening in childhood.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypercholesterolemia, Hypertension
- Trial name
- NCT00005439
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Microalbuminuria, Microalbuminuria /Creatinine Ratios ACR
New Taipei City 888 Digital Medical AI Platform for Prevention and Care of the Three Highs and Cardio-Renal-Vascular Diseases
Non-communicable diseases (NCDs), or chronic diseases, are a major public health burden globally and in Taiwan, and control of the "three highs" (hypertension, dyslipidemia, and hyperglycemia) is a national priority.
- Conditions
- Microalbuminuria, Microalbuminuria /Creatinine Ratios ACR, Cardiovascular Disease Risk Factor, Cardiovascular Disease Prevention
- Trial name
- DIGICARE-DREAM (NCT07588256)
- Testing
- Interactive digital modules, Antihypertensive Medication Management
- Where
- Taiwan
- Volunteers
- 4,162 people
- Sponsor
- New Taipei City Medical Association
Hypertriglyceridemia
RBD5044 in Chinese Participants With Hypertriglyceridemia
The goal of this clinical trial is to learn if drug RBD5044 works to treat hypertriglyceridemia in adults. It will also learn about the safety of drug RBD5044.
- Trial name
- NCT07587788
- Testing
- RBD5044
- Where
- 7 sites in China
- Volunteers
- 40 people
- Sponsor
- Ribotek Biopharmaceuticals (Shandong) Co., Ltd
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